TW202003577A - 用於在未曾接受過治療之個體治療癌症的標靶性TGF-β抑制之給藥方案 - Google Patents

用於在未曾接受過治療之個體治療癌症的標靶性TGF-β抑制之給藥方案 Download PDF

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TW202003577A
TW202003577A TW108116801A TW108116801A TW202003577A TW 202003577 A TW202003577 A TW 202003577A TW 108116801 A TW108116801 A TW 108116801A TW 108116801 A TW108116801 A TW 108116801A TW 202003577 A TW202003577 A TW 202003577A
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seq
protein
polypeptide
sequence
drug delivery
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TW108116801A
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勞利 歐傑佛
巴瓦伯 沙曼 艾爾
伊莎貝爾 杜沙特
優利亞 維格美斯特
阿卡許 坎德瓦
歐雷夫 克里史坦森
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德商馬克專利公司
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TW108116801A 2018-05-15 2019-05-15 用於在未曾接受過治療之個體治療癌症的標靶性TGF-β抑制之給藥方案 TW202003577A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862671963P 2018-05-15 2018-05-15
US62/671,963 2018-05-15
US201962804931P 2019-02-13 2019-02-13
US62/804,931 2019-02-13

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TW202003577A true TW202003577A (zh) 2020-01-16

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TW108116801A TW202003577A (zh) 2018-05-15 2019-05-15 用於在未曾接受過治療之個體治療癌症的標靶性TGF-β抑制之給藥方案

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US (1) US20210061899A1 (https=)
EP (1) EP3813868A4 (https=)
JP (1) JP2021523096A (https=)
KR (1) KR20210009339A (https=)
CN (1) CN112118858A (https=)
AU (1) AU2019271065A1 (https=)
BR (1) BR112020021082A2 (https=)
CA (1) CA3096844A1 (https=)
MX (1) MX2020011638A (https=)
SG (1) SG11202011148VA (https=)
TW (1) TW202003577A (https=)
WO (1) WO2019222252A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020402496A1 (en) * 2019-12-11 2022-06-16 WuXi Biologics Ireland Limited Bi-functional antibody against PD-L1 and TGFβ
PH12022552826A1 (en) * 2020-04-28 2024-03-11 Sinocelltech Ltd TgfãŸr2 extracellular domain truncated molecule, fusion protein of tgfãŸr2 extracellular domain truncated molecule and anti-egfr antibody, and anti-tumor use of fusion protein
US20230365653A1 (en) * 2020-07-24 2023-11-16 Mabwell (shanghai) Bioscience Co., Ltd. Tgf-beta rii mutant and fusion protein thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201216649D0 (en) * 2012-09-18 2012-10-31 Univ Birmingham Agents and methods
CA3081073C (en) * 2013-03-12 2023-09-12 Biocon Ltd. Fusion immunomodulatory proteins and methods for making same
US9676863B2 (en) * 2014-02-10 2017-06-13 Merck Patent Gmbh Targeted TGFβ inhibitors
US20170145103A1 (en) * 2015-11-23 2017-05-25 Five Prime Therapeutics, Inc. Predicting response to cancer treatment with fgfr2 inhibitors
EP3497130B1 (en) * 2016-08-12 2021-10-27 Merck Patent GmbH Combination therapy for cancer

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CA3096844A1 (en) 2019-11-21
MX2020011638A (es) 2022-02-10
JP2021523096A (ja) 2021-09-02
EP3813868A4 (en) 2022-03-02
EP3813868A1 (en) 2021-05-05
WO2019222252A1 (en) 2019-11-21
US20210061899A1 (en) 2021-03-04
SG11202011148VA (en) 2020-12-30
AU2019271065A1 (en) 2020-11-05
KR20210009339A (ko) 2021-01-26
CN112118858A (zh) 2020-12-22
BR112020021082A2 (pt) 2021-02-17

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