TW201733587A - 1,3,4-噻二唑化合物及其在治療癌症中之用途 - Google Patents
1,3,4-噻二唑化合物及其在治療癌症中之用途 Download PDFInfo
- Publication number
- TW201733587A TW201733587A TW105139337A TW105139337A TW201733587A TW 201733587 A TW201733587 A TW 201733587A TW 105139337 A TW105139337 A TW 105139337A TW 105139337 A TW105139337 A TW 105139337A TW 201733587 A TW201733587 A TW 201733587A
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- Prior art keywords
- methoxy
- phenyl
- thiadiazol
- amino
- compound
- Prior art date
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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| TW201731511A (zh) * | 2015-11-30 | 2017-09-16 | 阿斯特捷利康公司 | １，３，４-噻二唑化合物及其在治療癌症中之用途 |
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| CN105960405B (zh) | 2014-01-06 | 2021-02-19 | 理森制药股份公司 | 谷氨酰胺酶抑制剂 |
| EP3116872A4 (en) * | 2014-03-14 | 2017-08-30 | Calithera Biosciences, Inc. | Combination therapy with glutaminase inhibitors |
| GB201409624D0 (en) * | 2014-05-30 | 2014-07-16 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| GB201520959D0 (en) | 2015-11-27 | 2016-01-13 | Astrazeneca Ab And Cancer Res Technology Ltd | Bis-pyridazine compounds and their use in treating cancer |
| TW201730188A (zh) * | 2015-11-30 | 2017-09-01 | 阿斯特捷利康公司 | 1,3,4-噻二唑化合物及其在治療癌症中之用途 |
| US10323028B2 (en) | 2015-11-30 | 2019-06-18 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| TW201731511A (zh) | 2015-11-30 | 2017-09-16 | 阿斯特捷利康公司 | １，３，４-噻二唑化合物及其在治療癌症中之用途 |
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| BR112018010806A2 (pt) | 2018-11-27 |
| PH12018501131A1 (en) | 2019-01-21 |
| CA3005495A1 (en) | 2017-06-08 |
| AR106874A1 (es) | 2018-02-28 |
| EP3383873B1 (en) | 2022-03-09 |
| US20190389853A1 (en) | 2019-12-26 |
| EA201891241A1 (ru) | 2019-01-31 |
| US11753405B2 (en) | 2023-09-12 |
| WO2017093299A1 (en) | 2017-06-08 |
| SV2018005702A (es) | 2018-11-27 |
| MX2018006532A (es) | 2019-05-15 |
| US20170152255A1 (en) | 2017-06-01 |
| CN108349966B (zh) | 2022-02-15 |
| CL2018001407A1 (es) | 2018-10-12 |
| US10981904B2 (en) | 2021-04-20 |
| NI201800064A (es) | 2018-10-18 |
| KR20180083942A (ko) | 2018-07-23 |
| IL259510A (en) | 2018-07-31 |
| US10323028B2 (en) | 2019-06-18 |
| CA3005495C (en) | 2023-12-12 |
| SG11201803810XA (en) | 2018-06-28 |
| JP2018535986A (ja) | 2018-12-06 |
| US20210246131A1 (en) | 2021-08-12 |
| EP3383873A1 (en) | 2018-10-10 |
| AU2016363718B2 (en) | 2019-11-14 |
| AU2016363718A1 (en) | 2018-07-12 |
| RU2018123714A (ru) | 2020-01-09 |
| JP6999550B2 (ja) | 2022-02-10 |
| ES2914333T3 (es) | 2022-06-09 |
| CN108349966A (zh) | 2018-07-31 |
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