TW201703758A - Cosmetic for protection against ultraviolet radiation - Google Patents

Abstract

Provided is a cosmetic for protection against ultraviolet radiation, wherein the cosmetic has excellent storage stability, provides highly effective protection against ultraviolet radiation, feels good and does not leave a sticky feeling when used, and does not cause skin irritation. The cosmetic for protection against ultraviolet radiation contains components (A), (B), (C), (D) and (E), where (A) is 0.18-2 mass% of an ionic surfactant, (B) is 1-10 mass% of a hydrophobic amphiphilic material, (C) is 1-40 mass% of a liquid oil containing an oil-soluble ultraviolet absorbent, (D) is 0.01-6 mass% of a solid oil, and (E) is water. The cosmetic is obtained by means of a method comprising an emulsification step for mixing a composition containing components (A)-(D) with water (E) under heating to form an emulsion, and a cooling step for cooling the emulsion formed in the emulsification step at a cooling rate of 0.5-5 DEG C/s.

Description

UV protection cosmetics

The present invention relates to ultraviolet defense cosmetics.

The sun exposure by ultraviolet rays promotes browning of the skin, reduction of skin elasticity, wrinkles, and the like. Therefore, in order to prevent such phenomena, a cosmetic material blended with an ultraviolet absorber is used.

Among the ultraviolet absorbers, the oil-soluble ultraviolet absorber is excellent in the effect of absorbing ultraviolet rays. However, if it is directly blended in a cosmetic, there is a feeling of irritation or stickiness, and there is a problem in terms of feeling of use and the like.

Therefore, the cosmetics which are blended after the ultraviolet absorber is formed into a fine emulsion or blended after being encapsulated have been examined (for example, Patent Documents 1 to 3).

(Patent Document 1) Japanese Patent Laid-Open Publication No. 2012-31125

(Patent Document 2) Japanese Patent Laid-Open Publication No. 2005-504750

(Patent Document 3) Japanese Patent Laid-Open Publication No. 2009-167168

The ultraviolet-defense cosmetic material according to the present invention contains the components (A) and (B) shown below. (C), (D) and (E): (A) ionic surfactant 0.18-2% by mass, (B) hydrophobic amphiphilic substance 1 to 10% by mass, (C) oil-soluble ultraviolet absorber The liquid-based oil agent is 1 to 40% by mass, (D) the solid oil agent is 0.01 to 6% by mass, and the (E) water ultraviolet-ray-protecting cosmetic material is obtained by a method comprising the following steps: The composition of A)~(D) is emulsified by mixing with (E) water under heating to form an emulsion; and the emulsion formed by the emulsification step is cooled at a cooling rate of 0.5 to 5 ° C / sec. The cooling step.

20‧‧‧Emulsifying Department

21‧‧‧1st Emulsifying Department

22‧‧‧2nd Emulsifying Department

30‧‧‧ Cooling Department

31‧‧‧Inlet

32‧‧‧Exporting

33‧‧‧Spit tube

34, 35, 36, 37‧‧ ‧ jacket

40‧‧‧Vibrating mixing and mixing device

41‧‧‧Shell

42‧‧‧ drive shaft

43‧‧‧Agitating blades

44‧‧‧ stirring body

45a‧‧‧ vibrator

45b‧‧‧Connector

46‧‧‧ Compartment

47‧‧‧Mixed room

48‧‧‧Opening

49‧‧‧ gap

100‧‧‧ manufacturing equipment

211‧‧‧ mixing tank

212‧‧‧ Jacket

213‧‧‧Agitating blades

214‧‧‧Axis

215‧‧‧ motor

216‧‧‧ tube

221‧‧‧High Energy Processing Department

222‧‧‧ tube

Fig. 1 is a schematic view showing a vibrating stirring and mixing device suitable for producing the cosmetic of the present invention.

Fig. 2 is a schematic view showing a longitudinal section of the vibrating stirring and mixing device shown in Fig. 1.

Fig. 3 is an enlarged view of an essential part of a stirring body of the vibrating stirring and mixing device shown in Fig. 1.

The conventional cosmetic material blended with the ultraviolet absorber is poor in storage stability and is not sufficiently satisfied in terms of use.

Further, when the cosmetic containing the ultraviolet absorber is applied to the skin, since the ultraviolet absorber is not uniformly attached to the skin, sufficient ultraviolet defense effect cannot be obtained. fruit. Even when a large amount of the ultraviolet absorber is blended for the purpose of improving the ultraviolet protection effect, there is still a problem in terms of storage stability, feeling of use, and the like.

The present invention relates to an ultraviolet-ray protective cosmetic which uniformly disperses an oil agent containing an ultraviolet absorber, has excellent storage stability, has a high ultraviolet-ray defense effect, has a good feeling of use, and has no skin irritation.

The present inventors have found that an ionic surfactant, a hydrophobic amphiphilic substance, a liquid oil containing an oil-soluble ultraviolet absorber, and a solid oil agent are combined in a specific ratio and obtained in accordance with a specific method. The material is obtained by dispersing α-gel particles containing an oil-soluble ultraviolet absorber, and has excellent storage stability, high ultraviolet protection effect, good feeling of use, and no skin irritation.

The ultraviolet-ray-protecting cosmetic of the present invention is obtained by dispersing α-gel particles containing an oil-soluble ultraviolet absorber, and is also excellent in storage stability. Moreover, when applied to the skin, the oil-soluble ultraviolet absorber uniformly adheres to the skin, and can obtain a high ultraviolet ray-defense effect, is non-sticky, and has a good feeling of use, and the ultraviolet absorbing agent has low transdermal absorbability and does not have Skin irritation.

The ionic surfactant of the component (A) used in the present invention is a user of a general cosmetic, and an anionic surfactant, a cationic surfactant, an amphoteric surfactant, a neuroamine alcohol, and a salt thereof can be used.

The anionic surfactant may, for example, be a fatty acid salt having a carbon number of 12 to 24 such as sodium laurate, potassium palmitate or stearic acid; an alkyl sulfate salt such as sodium lauryl sulfate or potassium lauryl sulfate; An alkyl ether sulfate salt such as ethylene lauryl sulfate triethanolamine; N-mercapto sarcosinate such as sodium citrate sodium; fatty acid decyl sulfonate such as N-myristyl-N-methyl taurate; alkylphosphoric acid such as sodium monostearyl phosphate a salt; a polyoxyethylene alkyl ether phosphate such as polyoxyethylene oleyl ether phosphate, sodium polyoxyethylene stearyl ether phosphate; a long chain sulfosuccinate such as sodium di-2-ethylhexyl sulfosuccinate; Sodium lauryl glutamate, sodium N-lauric acid glutamate, sodium N-stearyl sulfonyl-L-glutamate, N-stearyl sulfhydryl-L-glutamic acid arginine, Long-chain N-mercapto glutamate such as N-stearyl glutamate, N-myristyl-L-glutamate, and the like.

Among these, long-chain N-mercapto glutamate is preferred from the viewpoint of enhancing the preservation stability of the ultraviolet-ray-defending cosmetic material, and from the viewpoint of improving the feeling of use and particularly reducing the stickiness.

The cationic surfactant is preferably a quaternary ammonium salt, for example, an alkyltrimethylammonium chloride such as stearyltrimethylammonium chloride or lauryltrimethylammonium chloride; or a dialkyldimethylammonium salt; Trialkylmethylammonium chloride, alkylamine salt, and the like.

The amphoteric surfactant may, for example, be an alkyl dimethyl amine oxide or an alkyl carboxyl beet. Alkyl sulfo beet , amidinoamine, alkyl amidoxib Alkyl-propylaminoglycan .

Examples of the neuroamine alcohol and its salt include natural neuroamine alcohol, dihydroneuraminol, phytorepositin, sphingolipid diol, dehydrosphingosine, dehydrogenated plant ceramide, And such N-alkyl groups (for example, N-methyl groups) and the like.

These may be from any of the natural extracts and compositions, and are commercially available. Things. Commercially available natural neuroamine alcohols include, for example, D-neuraminol (SIGMA-ALDRICH), DS-phytosphingosine (DOOSAN), and phytosphingosine (COSMO FARM).

Further, examples of the salts of the neuroamine alcohols include acidic amino acid salts such as glutamic acid and aspartic acid; basic amino acid salts such as arginine; inorganic acid salts such as phosphoric acid and hydrochloric acid; and acetic acid and the like. A monocarboxylic acid salt; a dicarboxylic acid salt such as succinic acid; an oxycarboxylic acid salt such as citric acid, lactic acid or malic acid; and the like, preferably one or more selected from the above.

The ionic surfactant of the component (A) is preferably an anionic surfactant and a neurolitol from the viewpoint of improving the storage stability of the ultraviolet-ray-protected cosmetic material, and improving the feeling of use and particularly reducing the stickiness. Among them, at least one, more preferably an anionic surfactant is selected.

Among the anionic surfactants, it is preferred to contain long-chain N-mercapto glutamate; and among the long-chain N-mercapto glutamate, it is preferred to use sodium glutamate, N, - Lauryl glutamate monosodium, N-stearyl sulfhydryl-L-glutamate, N-stearyl sulfhydryl-L-glutamic acid arginine, N-stearyl glutamate And at least one selected from the group consisting of N-myristyl-L-glutamate, more preferably from N-stearyl glutamate, N-stearyl-L-glutamic acid At least one of the acids is selected, and N-stearyl sulfhydryl-L-glutamic acid arginine is particularly preferred.

The component (A) may be used singly or in combination of two or more kinds, and the content is based on the viewpoint of improving the storage stability of the ultraviolet ray-protecting cosmetic material, and improving the feeling of use and particularly reducing the stickiness. The composition is 0.18% by mass or more, preferably 0.2. 5% by mass or more, more preferably 0.3% by mass or more, more preferably 0.4% by mass or more, still more preferably 0.45 mass% or more, and 2% by mass or less, preferably 1.5% by mass or less, more preferably 1.1% by mass or less, and still more It is preferably 0.9% by mass or less, and more preferably 0.7% by mass or less. Further, the content of the component (A) is 0.18 to 2% by mass, preferably 0.2 to 1.5% by mass, more preferably 0.3 to 1.1% by mass, still more preferably 0.4 to 0.9% by mass, and more preferably the total composition. Good system 0.45 ~ 0.7% by mass.

Further, in the present invention, the component (A) is contained in an amount based on an acid.

In addition, it is possible to contain a nonionic surfactant in the range which does not impair the effect of the present invention, and it is improved from the viewpoint of improving the storage stability of the ultraviolet-ray-protected cosmetic material, and the feeling of use is improved, and in particular, the viscosity is lowered. The content of the nonionic surfactant is preferably 1% by mass or less, more preferably 0.5% by mass or less, still more preferably 0.1% by mass or less, and still more preferably 0% by mass in the total composition.

The hydrophobic amphiphilic substance of the component (B) used in the present invention may, for example, be a ceramide, an alcohol having 10 to 24 carbon atoms, a linear saturated fatty acid having 10 to 24 carbon atoms, or a carbon number of 10~. 24 monoglyceride, 10 to 24 monoalkyl glyceryl ether, 10 to 24 mono-fatty sorbitan ester, and 10 to 24 mono-fatty sorbitan ester.

The ceramide may be one or more selected from the group consisting of natural ceramide and pseudo ceramide. The ceramide compound described in JP-A-2013-53146 is particularly preferable from the viewpoint of improving the preservation stability of the ultraviolet-ray-defending cosmetic.

Specific examples of the natural ceramide may be, for example, a brain which is amidated by a neuroamine alcohol, a dihydroneuraminol, a phytohormone or a sphingadienine. Indole type 1~7 (eg, Figure 2 of J. Lipid Res., 24:759 (1983), and pigs and humans as described in Figure 4 of J. Lipid. Res., 35:2069 (1994) Ceramide).

Further, these N-alkyl groups (for example, N-methyl groups) are also included.

These ceramides may be optically active (D(-)), or optically active (L(+)), or both natural and non-natural. mixture. The relative three-dimensional arrangement of the above compounds may be a natural stereo configuration, or a non-natural stereo configuration other than the above, or a mixture of the above. Tejia is the compound of CERAMIDE1, CERAMIDE2, CERAMIDE3, CERAMIDE5, CERAMIDE6II (all of which are INCI, 8th Edition) and the following formula:

These may be used from any of natural extracts and compositions, and commercially available products may also be used. Such commercially available natural ceramides include, for example, Ceramide I, Ceramide III, Ceramide IIIA, Ceramide IIIB, Ceramide IIIC, Ceramide VI (all of which are COSMO FARM); Ceramide TIC-001 (High Sand Perfume) ; CERAMIDE II (Quest International); DS-Ceramide VI, DS-CLA-Phytoceramide, C6-Phytoceramide, DS-ceramide Y3S (DOOSAN); CERAMIDE 2 (Sederma).

The pseudo-cerebral amine is preferably a pseudo-cerebral amine represented by the following general formula (1) from the viewpoint of improving the preservation stability of the ultraviolet-defense cosmetic: (wherein R ¹ represents a linear, branched, or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom having 10 to 22 carbon atoms which may be substituted by a hydroxyl group; and X ¹ represents a hydrogen atom or an ethylene group; Or a glyceryl group; R ² represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted by a hydroxyl group or an amine group, or an ester bond at the ω end of the hydrocarbon group. a saturated or unsaturated fatty acid having a linear or branched chain of 8 to 22 carbon atoms which may be substituted by a hydroxyl group; R ³ represents a hydrogen atom or may be a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an ethoxylated group. Substituted alkyl with a total carbon number of 1 to 30.)

Among these, from the viewpoint of improving the preservation stability of the ultraviolet-defense cosmetic, it is more preferable to be a pseudo-cerebral amine represented by the following formula: [Chemical 4]

The general formula (1) is preferably wherein R ¹ is hexadecyl, X ¹ is a hydrogen atom, R ² is a pentadecyl group, R ³ is a hydroxyethyl group, or R ¹ is a hexadecyl group, and X ¹ is A pseudo-cerebral amine having a hydrogen atom, R ² is a fluorenyl group, and R ³ is a hydroxyethyl group, more preferably R ¹ of the general formula (1) is a hexadecyl group, X ¹ is a hydrogen atom, and R ² is ten. Pentaalkyl, R ³ is hydroxyethyl [N-(hexadecyloxyhydroxypropyl)-N-hydroxyethylhexadecaneamine]. Further, preferred are pseudo-cerebral amines (i) and (ii) represented by the following formula.

Further, examples of the alcohol having 10 to 24 carbon atoms include myristyl alcohol, cetyl alcohol, stearyl alcohol, decanediol, and oleyl alcohol. Among these, it is preferred to have a linear alkyl group, more preferably a carbon number of 16 to 18 alcohols, and particularly preferably at least one or two or more selected from the group consisting of cetyl alcohol and stearyl alcohol. Contains cetyl alcohol and stearyl alcohol.

Examples of the linear saturated fatty acid having 10 to 24 carbon atoms include lauric acid, myristic acid, palmitic acid, stearic acid, and eucalyptus acid. Among these, from the viewpoint of preservation stability of the ultraviolet-ray-defending cosmetic material and the effect of enhancing the ultraviolet-ray defense effect, a linear saturated fatty acid having a carbon number of 14 to 22 is preferred, and a carbon number of 16 to 22 is preferred. The linear saturated fatty acid preferably contains at least one selected from the group consisting of palmitic acid and stearic acid.

Examples of the mono-fatty acid glyceride having 10 to 24 carbon atoms include glycerol monolaurate, glycerin monomyristate, glyceryl monopalmitate, glyceryl monostearate, glycerol monophthalate, and glycerin monooleate. Acid ester, glycerol monoisostearate, and the like. Among these, it is preferred to select at least one or two or more selected from the group consisting of glycerol monophthalate, glycerin monostearate, and glycerol monopalmitate, and more preferably glycerol monophthalate.

Examples of the monoalkyl glyceryl ether having 10 to 24 carbon atoms include monodecyl glyceryl ether, monolauryl glyceryl ether, monomyristyl glyceryl ether, monocetyl glyceryl ether, monostearyl glyceryl ether, and monoterpenes. Dialkyl glyceryl ether and the like.

Examples of the mono-fatty acid sorbitan ester having 10 to 24 carbon atoms include sorbitan monolaurate, sorbitan monosuccinate, sorbitan monopalmitate, and sorbitan monostearate. , eucalyptus sorbitan, etc.

The component (B) is preferably an alcohol having a carbon number of 14 to 22 and a monoglyceride having a carbon number of 14 to 22, from the viewpoint of the preservation stability of the ultraviolet-ray-defending cosmetic material and the effect of enhancing the ultraviolet protection effect. At least one or two or more selected from the group consisting of a monoalkyl glyceryl ether having 14 to 22 carbon atoms and a sorbitan ester having a carbon number of 14 to 22, more preferably a carbon number At least one or two or more selected from the group consisting of 16 to 22 alcohols and 16 to 22 carbon fatty acid glycerides, and at least 1 selected from the group consisting of cetyl alcohol, stearyl alcohol, and lipophilic monoglyceride. Kind or more than two.

Further, from the same viewpoint, the component (B) preferably contains an alcohol having 14 to 22 carbon atoms, a monoglyceride having 14 to 22 carbon atoms, a monoalkyl glyceryl ether having 14 to 22 carbon atoms, At least one of the mono-fatty sorbitan esters having a carbon number of 14 to 22 is selected, and more preferably, it has an alcohol having 14 to 22 carbon atoms and a monoglyceride having a carbon number of 14 to 22, and particularly preferably contains carbon atoms. The alcohol of 16-22, and the monoglyceride of carbon number 16-22, preferably contains cetyl alcohol, stearyl alcohol, and a monoglyceride having a carbon number of 16-22.

The component (B) may be used singly or in combination of two or more kinds, and the content thereof is based on the viewpoint of improving the storage stability of the ultraviolet-ray-protecting cosmetic material, improving the ultraviolet-ray defense effect, and improving the feeling of use, in particular, The total composition is 1% by mass or more, preferably 1.5% by mass or more, more preferably 2% by mass or more, still more preferably 2.5% by mass or more, and 10% by mass or less, and more preferably 10% by mass or less. 8 mass% or less, more preferably 5% by mass or less, still more preferably 3.8 mass% or less. Further, the content of the component (B) is 1 to 10% by mass, preferably 1.5 to 8% by mass, more preferably 2 to 5% by mass, still more preferably 2.5 to 3.8% by mass in the total composition.

The component (C) used in the present invention is a liquid oil containing an oil-soluble ultraviolet absorber.

As the oil-soluble ultraviolet absorber, a user of a general cosmetic can be used. The oil-soluble ultraviolet absorber can be, for example, high salicylic acid Salicylic acid such as ester, octyl salicylate, triethanolamine salicylate; p-aminobenzoic acid, ethyldihydroxypropyl-p-aminobenzoic acid, glycerol-aminobenzoic acid, octyldimethylammonium Benzoic acid, amyl p-dimethylaminobenzoate, 2-ethylhexyl p-dimethylaminobenzoate, etc., p-aminobenzoic acid; p-methoxycinnamate-2-ethylhexyl ( For example, Uvinul® MC80; manufactured by BASF), di-p-methoxycinnamic acid mono-2-ethylhexanoic acid glyceride, 2,5-diisopropyl cinnamic acid methyl ester, trimethoxy cinnamic acid methyl ester bis ( Trimethyl decyloxy) decyl isoamyl ester, p-methoxy cinnamic acid isopropyl ester. Citrate acid such as diisopropyl cinnamate mixture, p-methoxy hydrogenated cinnamic acid diethanolamine salt; octocrylene (for example, PARSOL® 340; manufactured by DSM Nutrition Japan), 1-(3,4- Dimethoxyphenyl)-4,4-dimethyl-1,3-pentanedione, cinoxate, methyl-O-aminobenzoate, 3-(4-methylbenzene Methylene) camphor; 4-(2-β-glucopyranosyloxy)propoxy-2-hydroxydiphenyl ketone, dihydroxydimethoxydiphenyl ketone, dihydroxydimethoxy hydride Sodium phenyl ketone disulphonate, 2-hydroxy-4-methoxydiphenyl ketone, 2-hydroxy-4-methoxydiphenyl ketone-5-sulfate, 2,2'-dihydroxy-4- Methoxydiphenyl ketone, 2,4-dihydroxydiphenyl ketone, 2,2'4,4'-tetrahydroxydiphenyl ketone, 2,2'-dihydroxy-4,4'-dimethyl a diphenyl ketone such as oxydiphenyl ketone or 2-hydroxy-4-N-octyloxydiphenyl ketone; 2,4,6-gin[4-(2-ethylhexyloxycarbonyl)anilinyl ]-1,3,5-three (eg Uvinul® T150; manufactured by BASF), bisethylhexyloxyphenol methoxyphenyl three (eg TINOSORB S; BASF system), etc. 2-phenyl-benzimidazole-5-sulfate, 4-isopropyldibenylmethane, 4-tert-butyl-4'-methoxybenzhydrylmethane (eg PARSOL® 1789; DSM Nutrition Japan Co., Ltd.), such as benzhydrylmethane; dimethoxybenzylidene dioxyimidazolium propionate-2-ethylhexyl ester (for example, SOFT SHADE DH; manufactured by Ajinomoto Co., Ltd.) Ethyl hydroxybenzhydrylbenzoate (for example, Uvinul® Aplus; manufactured by BASF), methylenebisbenzotriazolyl tetramethylbutylphenol (for example, TINOSORB M; manufactured by BASF), and the like.

Further, in the ultraviolet absorber, the agent itself is solid at normal temperature. but, Since each component of the ultraviolet-ray protective cosmetic of the present invention is mixed with the component (E) under heating, it is considered that the oil-soluble ultraviolet absorber of the component (C) is present in a liquid state in the obtained ultraviolet-defense cosmetic.

Among these, from the viewpoint of enhancing the ultraviolet protection effect, it is preferably from p-methoxycinnamic acid-2-ethylhexyl ester (for example, Uvinul® MC80; manufactured by BASF Corporation), orocrylin (for example, PARSOL). ® 340; DSM Nutrition Japan, 2,4,6-gin[4-(2-ethylhexyloxycarbonyl)anilino]-1,3,5-three (eg Uvinul® T150; manufactured by BASF), 4-tert-butyl-4'-methoxybenzhydrylmethane (eg PARSOL® 1789; manufactured by DSM Nutrition Japan), dimethoxybenzamide 2-diethylimidazolium propionate-2-ethylhexyl ester (for example, SOFT SHADE DH; manufactured by Ajinomoto Co., Ltd.), diethylaminohydroxybenzhydrylbenzoate (for example, Uvinul® Aplus; manufactured by BASF Corporation), Diethylhexyloxyphenol methoxyphenyl three One type or two or more types are selected, for example, from TINOSORB S; manufactured by BASF Corporation. Further, from the same viewpoint, it is more preferable to use 2-methoxyhexyl methoxycinnamate (for example, Uvinul® MC80; manufactured by BASF Corporation), diethylhexyl hydroxybenzimidyl benzoate. (eg Uvinul® Aplus; manufactured by BASF), bisethylhexyloxyphenol methoxyphenyl three One type or two or more types are selected, for example, from TINOSORB S; manufactured by BASF Corporation.

Further, from the same viewpoint, the oil-soluble ultraviolet absorber is more preferably derived from the above-mentioned cinnamic acid-based oil-soluble ultraviolet absorber, diethylaminohydroxybenzoylbenzoic acid hexyl ester, and the above three One or two or more kinds of the oil-soluble ultraviolet absorbers are selected, and the three oil-soluble ultraviolet absorbers are particularly preferably contained, and the most preferred ones are: p-methoxycinnamic acid-2-ethylhexyl ester (for example, Uvinul® MC80; manufactured by BASF Corporation, hexyl diethyl hydroxybenzhydrylbenzoate (for example, Uvinul® Aplus; manufactured by BASF Corporation), and bis-hexyloxyphenol methoxyphenyl trisole (eg, TINOSORB S; manufactured by BASF Corporation).

Further, the liquid oil other than the oil-soluble ultraviolet absorber is fluid at 25 ° C. There is no limitation as long as it is a user of a general cosmetic material, and examples thereof include a linear or branched hydrocarbon oil such as a liquid paraffin, a light isoparaffin, a squalane or a squalene; a neopentyl glycol dicaprate; Fatty acid esters such as isopropyl palmitate and alkyl benzoate; ester oils such as polyol fatty acid esters such as pentaerythritol tetra-2-ethylhexanoate; dimethyl polyoxane, dimethylcyclopolyfluorene Polyoxyphthalic acid such as oxyalkylene, methylphenyl polyoxyalkylene, methyl hydrogen polyoxyalkylene, higher alcohol modified polyoxyxene oil; fluoropolyether, perfluoroalkyl ether, polyfluorene, etc. Wait. These may also be natural oils such as jojoba oil, vegetable oils such as olive oil, and animal oils such as liquid lanolin.

Among these, the liquid oil agent other than the oil-soluble ultraviolet absorber is preferably a linear or branched hydrocarbon from the viewpoint of reducing the viscosity and improving the compatibility with the oil-soluble ultraviolet absorber. At least one of oil, ester oil, and polyoxylized oil is selected.

In the total liquid oil, the content of the oil-soluble ultraviolet absorber is preferably 60% by mass or more, more preferably 65% by mass or more, from the viewpoint of improving the ultraviolet ray-protecting effect and reducing the skin irritation. Further, it is more preferably 70% by mass or more, and is preferably 100% by mass or less, more preferably 95% by mass or less, still more preferably 85% by mass or less. Further, the component (C) is preferably contained in the total liquid oil, and the content of the oil-soluble ultraviolet absorber is 60 to 100% by mass, more preferably 65 to 90% by mass, still more preferably 70 to 85% by mass.

In the oil-soluble ultraviolet absorber, the content of the cinnamic acid-based oil-soluble ultraviolet absorber is preferably from 60 to 100% by mass, more preferably from 70 to 90% by mass, from the viewpoint of enhancing the protective effect and reducing the skin irritation. From the same point of view, in the oil-soluble UV absorber, three The total content of the oil-soluble ultraviolet absorber and diethylhexyl hydroxybenzimidyl benzoate is preferably 0 to 40% by mass, more preferably 10 to 30% by mass.

Further, among the oil-soluble ultraviolet absorbers, the cinnamic acid-based oil-soluble ultraviolet absorber is relatively three The ratio of the amount of the oil-soluble ultraviolet absorber to the diethylhexyl hydroxybenzoylbenzoic acid hexyl ester (cinnamic acid-based oil-soluble ultraviolet absorber / [three It is an oil-soluble ultraviolet absorber + diethylhexyl hydroxybenzhydryl benzoate], preferably from 9/1 to 5/5, from the viewpoint of enhancing the ultraviolet protection effect and reducing skin irritation. Good 8.5/1.5~6/4, and even better 8/2~6.5/3.5.

In the ultraviolet-ray-protecting cosmetic, the content of the oil-soluble ultraviolet absorber is preferably 6% by mass or more, more preferably 8% by mass or more, from the viewpoint of enhancing the ultraviolet ray-protecting effect and reducing the skin irritation. Further, it is more preferably 10% by mass or more, and is preferably 20% by mass or less, more preferably 18% by mass or less, still more preferably 15% by mass or less. Further, in the ultraviolet-ray protective cosmetic, the content of the oil-soluble ultraviolet absorber is preferably 6 to 20% by mass, more preferably 8 to 18% by mass, still more preferably 10 to 15% by mass, based on the total composition.

The component (C) may be used singly or in combination of two or more kinds, and the content thereof is based on the viewpoint of improving the ultraviolet ray-protecting effect, reducing the skin irritation, and feeling good, and particularly reducing the stickiness. The composition is 1% by mass or more, preferably 3% by mass or more, more preferably 10% by mass or more, still more preferably 12% by mass or more, and 40% by mass or less, preferably 35% by mass or less, and more preferably 25% by mass or less. More preferably, it is 17% by mass or less. Further, the content of the component (C) is from 1 to 40% by mass, preferably from 3 to 35% by mass, more preferably from 10 to 25% by mass, still more preferably from 12 to 17% by mass, based on the total composition.

In the present invention, the mass ratio [(A)/(C)] of the component (A) to the component (C) is preferably 0.01 or more, more preferably from the viewpoint of improvement in storage stability of the ultraviolet-ray-protected cosmetic. 0.015 or more, more preferably 0.025 or more, still more preferably 0.034 or more, and more preferably 0.2 or less, more preferably 0.12 or less, still more preferably 0.06 or less, still more preferably 0.05 or less. Further, the mass ratio [(A)/(C)] of the component (A) to the component (C) is preferably 0.01 to 0.2, more preferably 0.015 to 0.12, still more preferably 0.025 to 0.06, still more preferably 0.034. 0.05.

In the present invention, the mass ratio [(B)/(C)] of the component (B) to the component (C) is based on the viewpoint of improving the preservation stability of the ultraviolet-ray-protected cosmetic material and the feeling of use, and particularly From the viewpoint of reducing the stickiness, it is preferably 0.01 or more, more preferably 0.12 or more, still more preferably 0.18 or more, still more preferably 0.19 or more, and more preferably 0.5 or less, more preferably 0.39 or less, still more preferably 0.27 or less, and further More preferably, it is 0.24 or less. Further, the mass ratio [(B)/(C)] of the component (B) to the component (C) is preferably 0.01 to 0.5, more preferably 0.12 to 0.39, still more preferably 0.18 to 0.27, and more preferably 0.19. ~0.24.

The solid oil of the component (D) is solid at 25 ° C.

The solid oil agent is not limited as long as it is a user of a general cosmetic, and may, for example, be candelilla wax (melting point: 66-71 ° C), rice wax (melting point: 77-86 ° C), sunflower Plant wax (melting point: 65-80 ° C), palm wax (melting point: 80-86 ° C), wood wax (melting point: 50-56 ° C) and other vegetable wax; beeswax (melting point: 62/65 ° C), whale wax (Methane: 42-52 ° C) and other animal waxes; montan wax (82-95 ° C), ground wax (melting point: 66-78 ° C) and other mineral wax; microcrystalline wax (melting point: 60-90 ° C), paraffin (40-70 ° C), petroleum wax such as ceresin (60-80 ° C); hardened castor oil (melting point: 85 ° C), hydrogenated jojoba oil (melting point: 66-70 ° C), 12-hydroxystearic acid (M.p.: 75-78 ° C), decylamine stearate (melting point: 101 ° C), polyoxyxylene wax (melting point 28-80 °C), synthetic wax such as polyethylene wax (melting point: 94-152 ° C), and the like.

In the present invention, the melting point of the solid oil agent is measured in accordance with the specifications of the external raw materials of the Ministry of Medicine, General Test Method 70. Melting point measurement method.

The component (D) is preferably a solid oil having a melting point of 60° C. or more and 80° C. or less, from the viewpoint of performing accurate temperature control in the cooling step described later and improving the storage stability of the cosmetic material. A wax of 60 ° C or more and 80 ° C or less. For example, candelilla wax MK-2 (manufactured by Hengguan Oil & Fats Co., Ltd., melting point: 71 ° C), refined rice wax S-100 (manufactured by Hengguan Oil & Fats Industry Co., Ltd., melting point: 78 ° C), and refined Sunflower seed wax (manufactured by Hengguan Oil & Fats Co., Ltd., melting point: 76 ° C), BEES WAX SP (manufactured by Strahl & Pitsch, melting point: 62-65 ° C), WHITE OZOKERITE WAX 1025 (manufactured by Strahl & Pitsch, melting point: 68.3- 71.1°C), MULTIWAX (manufactured by SONNEBORN, melting point 75°C), HNP-3 (made by Nippon Seiko Co., Ltd., melting point 64°C), HNP-9 (made by Nippon Seiko Co., Ltd., melting point 75°C), HNP-11 (Japan) Commercially available products such as Seiko Co., Ltd., melting point 68 ° C), ozoke #810 (manufactured by Nikko Rica Co., melting point 74 ° C).

In addition, the component (D) is preferably one or more selected from the group consisting of ceresin and paraffin, and has a melting point of 60° C. or more, from the viewpoint of improving the storage stability of the skin cosmetic and reducing the stickiness. A solid oil below 80 °C.

The component (D) may be used singly or in combination of two or more kinds, and the content is improved from the viewpoint of improving the storage stability of the skin cosmetic material and the feeling of use, and particularly reducing the stickiness. From the viewpoint of the effect, the total composition is 0.01% by mass or more, preferably 0.08% by mass or more, and more preferably 0.1% by mass or more. Further, it is more preferably 0.5% by mass or more, and is 6% by mass or less, preferably 4.5% by mass or less, more preferably 2.5% by mass or less, still more preferably 1.5% by mass or less. Further, the content of the component (D) is 0.01 to 6% by mass, preferably 0.08 to 4.5% by mass, more preferably 0.1 to 2.5% by mass, still more preferably 0.5 to 1.5% by mass, based on the total composition.

In the present invention, the mass ratio [(D)/(C)] of the component (D) to the component (C) is improved from the viewpoint of improving the storage stability of the ultraviolet-ray-protected cosmetic material, and the use feeling, the special system. From the viewpoint of reducing the stickiness, it is preferably 0.01 or more, more preferably 0.02 or more, still more preferably 0.04 or more, and is preferably 0.5 or less, more preferably 0.3 or less, still more preferably 0.1 or less. Further, the mass ratio [(D)/(C)] of the component (D) to the component (C) is preferably 0.01 to 0.5, more preferably 0.02 to 0.3, still more preferably 0.04 to 0.1.

The component (E) used in the present invention is water, and the remaining amount of each component is considered to be a stable α-gel structure in the cosmetic by the combination of the components (A) to (C) and (E). Emulsified particles. By having an alpha gel structure, a liquid oil containing an oil-soluble ultraviolet absorber can be contained in the alpha gel structure. A cosmetic material containing an emulsified particle having an α-gel structure is known to have a space for improvement in terms of higher requirements for ultraviolet rays, a feeling of use, and a feeling of skin irritation in recent years.

In addition to the components (A) to (C) and (E), the cosmetic of the present invention contains the component (D), and the oil agent containing the ultraviolet absorber can be uniformly dispersed and stored by being produced by the method described later. Excellent stability, high UV protection, good feeling of use, and no skin irritation.

The content of the component (E) is preferably from 35% by mass or more, more preferably from the viewpoint of improving the storage stability of the ultraviolet-ray-protecting cosmetic material and improving the moisture sensation. 45 mass% or more, more preferably 65 mass% or less, still more preferably 55 mass% or less. Further, the content of the component (E) is preferably from 35 to 65 mass%, more preferably from 45 to 55 mass%, based on the total composition.

The ultraviolet-defense cosmetic of the present invention can further contain (F) a water-soluble polymer, which can enhance the preservation stability of the ultraviolet-defense cosmetic and enhance the ultraviolet protection effect.

The water-soluble polymer is not limited as long as it is a user of a general cosmetic, and any of a natural polymer, a semi-synthetic polymer, and a synthetic polymer can be used.

Examples of the natural polymer include, for example, Sanxian gum, carrageenan, and alginic acid. Examples of the semisynthetic polysaccharide-based polymer include modified polysaccharides such as hydroxycellulose, hydroxypropylcellulose, sodium carboxymethylcellulose, methylcellulose, hydroxymethylcellulose, and cationized cellulose. Examples of the synthetic polymer include carbomer (crosslinked polyacrylic acid), polyacrylic acid, sodium polyacrylate, acrylic acid/alkyl methacrylate copolymer, polypropylene decylamine, (Na/acrylic acid acrylate). Alkyl dimethyl taurate Na) copolymer, (hydroxyethyl acrylate / propylene dimethyl dimethyl taurate) copolymer, (acrylamide / ammonium acrylate) copolymer, acrylic acid -13 and other acrylic An acrylic polymer such as a polymer; polyvinylpyrrolidone, polyvinyl alcohol, or cationized polyvinylpyrrolidone. Among these, acrylic polymers are preferred, and more preferred are carbomer, acrylic acid/alkyl methacrylate copolymer, polypropylene decylamine, (Na/acryloyldimethyltauryl acrylate) At least one of Na) copolymer, (hydroxyethyl acrylate/propylene decyldimethyltaurine Na) copolymer, (acrylamide/ammonium acrylate) copolymer, and polyacrylate-13 is selected. From (Na/acryl dimethyldimethyltaurate Na) copolymer, (hydroxyethyl acrylate/propylene dimethyldimethyltaurate) copolymer, (acrylamide/ammonium acrylate) copolymer Polypropylene At least one of the acid esters -13 is selected.

Commercial products of carbomer may, for example, be Carbopol® 910, Carbopol® 934, Carbopol® 940, Carbopol® 941, Carbopol® 980, Carbopol® 981 (all of which are manufactured by Lubrizol Advanced Materials, Inc.), etc.; Commercially available products of the alkyl methacrylate copolymer include, for example, Carbopol® 1382, Carbopol® ETD2020, PEMULEN TR-1, and PEMULEN TR-2 (all of which are manufactured by Lubrizol Advanced Materials, Inc.); The commercially available product of the amine may, for example, be SEPIGEL 305 (manufactured by SEPPIC Co., Ltd.) or the like; and a commercially available product of (Na/acryl dimethyl dimethyl taurate Na) copolymer may, for example, be SIMULGEL EG (manufactured by SEPPIC). For example, commercially available products of (hydroxyethyl acrylate/propylene decyldimethyltaurine Na) copolymer include, for example, SIMULGEL FL, SIMULGEL NS, SEPIPLUS S, and SEPINOV EMT 10 (all of which are manufactured by SEPPIC). .

The component (F) may be used singly or in combination of two or more kinds, and the content is preferably 0.3% by mass or more, more preferably 0.5% by mass, based on the total composition of the emulsified particles. The above is preferably 1.5% by mass or less, more preferably 1.0% by mass or less. Further, the content of the component (F) is preferably from 0.3 to 1.5% by mass, more preferably from 0.5 to 1.0% by mass, based on the total composition.

The ultraviolet-defense cosmetic of the present invention can further contain an ultraviolet scattering agent, which can further enhance the ultraviolet protection effect. The ultraviolet ray scattering agent is not limited as long as it is a user of a general cosmetic material, and examples thereof include metal oxides such as titanium oxide, zinc oxide, and cerium oxide; metals such as cerium and aluminum.

These ultraviolet scattering agents may have a spherical shape or a spinning shape. Further, the average particle diameter is preferably from 0.005 to 0.5 μm, more preferably from 0.007 to 0.2 μm, particularly preferably from 0.01 to 0.07 μm.

Here, the average particle diameter is obtained by measuring the maximum short diameter of the particle diameter of 300 particles in the image by a transmission electron microscope (TEM) at a condition of 100,000 times, and calculating the average value. In the present invention, the "maximum short diameter" means a short diameter having a largest diameter among short diameters orthogonal to the long diameter.

These ultraviolet light scattering agents are preferably subjected to conventionally known surface treatments from the viewpoints of enhancing the ultraviolet protection effect, as well as improving the preservation stability and reducing the stickiness, for example, fluorine compound treatment (preferably Fluoroalkyl phosphate treatment, perfluoroalkyl decane treatment, perfluoropolyether treatment, fluoropolyoxygen treatment, fluorinated polyoxyl resin treatment), polyoxane treatment (preferably methyl hydrogen polyoxymethane) Treatment, treatment with dimethyl polyoxane, gas phase tetramethyltetrahydrocyclotetraoxane treatment, polyoxygen resin treatment (preferably trimethyl decyloxy decanoic acid treatment), suspension treatment ( Method for addition of alkyl chain by gas phase polymerization, decane coupling agent, titanium coupling agent treatment, decane treatment (preferably alkyl decane, alkyl decazane treatment), oil treatment , N-thiolated lysine treatment, polyacrylic acid treatment, metal soap treatment (preferably stearic acid, myristate), acrylic resin treatment, metal oxide treatment, etc., more preferably combined with multiple These treatments.

For example, after coating the surface of the titanium oxide with a metal oxide such as decane or alumina, surface treatment with an alkyl decane or a fatty acid is carried out. It is preferred to treat the surface of the titanium oxide with alumina and then perform surface treatment with the fatty acid. Moreover, the surface treatment of the ultraviolet scattering agents is preferably carried out by surface treatment with a carboxyl compound, and is preferably utilized. The fatty acid having a carbon number of 12 to 22 is subjected to a surface treatment, and the special product is subjected to a surface treatment using a fatty acid having a carbon number of 14 to 20.

The ultraviolet ray scattering agent may be used alone or in combination of two or more kinds, and the content is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, and still more preferably 1% by mass, based on the total composition. The above is preferably 10% by mass or less, more preferably 8% by mass or less, still more preferably 5% by mass or less. Further, the content of the ultraviolet ray scattering agent is preferably from 0.1 to 10% by mass, more preferably from 0.5 to 8% by mass, still more preferably from 1 to 5% by mass, based on the total composition.

The ultraviolet-deficient cosmetic of the present invention may further suitably contain components other than the components (A) to (F), such as tackifiers, bactericides, humectants, humectants, colorants, and preservatives. , touch enhancer, powder, spices, anti-inflammatory agents, whitening agents, sweating agents, antioxidants, etc.

The ultraviolet ray-protecting cosmetic of the present invention is produced by a method comprising the steps of: emulsification step of mixing the composition containing the components (A) to (D) with (E) water under heating to form an emulsion And a cooling step of cooling the emulsion formed according to the above emulsification step at a cooling rate of 0.5 to 5 ° C / sec.

Further, when the ultraviolet-ray protective cosmetic of the present invention contains the component (F), the method for producing the ultraviolet-defining cosmetic preferably includes mixing a part of the component (E) with the component (F) in advance. The liquid and the step of mixing the emulsion obtained by the above cooling step.

In the emulsification step, a homomixer, an ultrasonic emulsifier, a high-pressure emulsifier, etc., which are usually used in the manufacture of a cosmetic, are used, and the compound is blended under heating, preferably 60 to 120 ° C, more preferably 80 to 100 ° C. Mixing is carried out to obtain an emulsion.

Furthermore, in the cooling step, the obtained emulsion can be used, using a vibrating stirring and mixing device, a scraper type heat exchanger (Onlator Sakura Manufacturing Co., Ltd.), a static mixer (Noritake Co., Ltd.), a general plate type heat exchanger, Double tube heat exchanger, etc., continuous rapid cooling method; or a method of stirring and cooling in a general blending tank, and the cooling rate is from the viewpoint of forming an α-gel structure, and curing the solid oil agent The viewpoint is 0.5 ° C / sec or more, more preferably 0.8 ° C / sec or more, and 5 ° C / sec or less, preferably 1.5 ° C / sec or less. Further, the cooling rate of the emulsion is 0.5 to 5 ° C / sec, preferably 0.8 to 1.5 ° C / sec.

It is preferred to cool to below the curing temperature of the oil component by such a cooling step.

In the above emulsification step and cooling step, the emulsification step uses a high-pressure emulsifier or an ultrasonic emulsifier, and the cooling step is performed by using a stirring shaft composed of a drive shaft and a stirring blade mounted on the drive shaft in the tubular casing. a vibrating stirring and mixing device that vibrates the drive shaft in the axial direction, wherein the agitating blade is provided with one or more openings and/or one or more notches; and the emulsion obtained by the emulsification step is preferably utilized The cooling step is continuously cooled by passing through the inside of the vibrating stirring and mixing device, whereby a cosmetic (fine particle dispersion) in which fine emulsified particles are dispersed can be obtained.

More specifically, Fig. 1 shows a schematic view of a manufacturing apparatus which is more suitably used in the present invention. The manufacturing apparatus 100 shown in FIG. 1 is equipped with the emulsification part 20 and the cooling part 30. The emulsification unit 20 is a composition containing components (A) to (D) and is mixed with (E) water under heating. Into an emulsion. The cooling unit 30 cools the formed emulsion. Further, the emulsification unit 20 includes the first emulsification unit 21 and the second emulsification unit 22. The first emulsification unit 21 fills all or a part of the components constituting the fine particle dispersion, and mixes the filled components with water under heating to obtain a pre-emulsified product. The second emulsification unit 22 is located on the downstream side of the first emulsification unit 21, and applies high energy to the pre-emulsified product obtained by the first emulsification unit 21 to obtain a fine emulsion. The cooling unit 30 is located on the downstream side of the emulsification unit 20, and cools the emulsion which is heated and mixed to a curing temperature of the solid oil component at 25° C. to obtain a target fine particle dispersion.

The first emulsification unit 21 of the emulsification unit 20 is provided with a mixing tank 211 as shown in FIG. 1 . The mixing tank 211 is heated by the jacket 212 covering the side of the mixing tank 211, and is adjusted to a predetermined temperature. A stirring blade 213 is provided in the mixing tank 211. The agitating blade 213 is coupled to a motor 215 provided outside the mixing tank 211 via a shaft 214, and is rotatable. At the bottom of the mixing tank 211, a tube 216 for taking out the pre-emulsion mixed in the tank 211 is connected. The tube 216 is connected to the second emulsification portion 22 via a valve. Further, for the purpose of quantitatively supplying the pre-emulsified product obtained by the first emulsification unit 21, a pump (not shown) may be provided in the middle of the tube 216 as needed.

For the first emulsification unit 21 having the above configuration, TK COMBIMIX (trade name) manufactured by PRIMIX Co., Ltd., TK AGI HOMO MIXER (trade name) manufactured by PRIMIX Co., Ltd., or the like can be used. These agitating devices are mainly used alone, but may be used in combination of two or more kinds as appropriate.

The second emulsification unit 22 of the emulsification unit 20 is provided with high energy treatment as shown in FIG. 1 . Department 221. The high-energy treatment unit 221 is configured to apply high energy to the pre-emulsified product obtained by the first emulsification unit 21 by using a high-pressure emulsifier or an ultrasonic emulsifier.

A tube 222 for taking out an emulsion in which high energy is applied to the high-energy processing unit 221 is connected to a downstream portion of the high-energy processing unit 221. The emulsion obtained by the second emulsification unit 22 is passed through the tube 222 and supplied to the cooling unit 30. Further, for the purpose of quantitatively supplying the emulsion obtained by the second emulsification unit 22, a pump (not shown) may be provided in the middle of the tube 222 as needed.

When the second emulsification unit 22 having the above-described configuration is a high-pressure emulsifier, for example, a Star Burst minimo (product model: HJP-25001) (manufactured by Sugino Machine Co., Ltd.) or ULTIMAIZER (manufactured by Sugino Machine Co., Ltd.) belonging to a high-pressure emulsifier can be used. Gaulin (manufactured by APV Rannie Co., Ltd.), a microfluidizer (manufactured by Microfluidics Co., Ltd.), a high-pressure jet emulsifier (manufactured by BEE Co., Ltd.), and the like.

In addition, when the second emulsification unit 22 is an ultrasonic emulsifier, for example, IKASONIC (product model: U200S) (manufactured by IKA) and ultrasonic homogenizer (including manufactured by Nippon Seiki Co., Ltd.) equipped with an ultrasonic generation amplifier can be used. ), ultrasonic homogenizer (made by Ultrasonic Industries, Inc.). The above-mentioned high-pressure emulsifier or ultrasonic emulsifier is mainly used alone, but may be used in combination of two or more kinds as appropriate.

The cooling unit 30 is provided with a vibrating stirring and mixing device 40. The vibrating stirring and mixing device 40 has a slightly cylindrical structure, and has an inflow port 31 connected to the tube 222 at one end side and a discharge port 32 at the other end side. The discharge port 32 is connected to the discharge pipe 33. The emulsion supplied from the emulsification section 20 is supplied to the vibratory stirring mixture through the inflow port 31. Inside the apparatus 40, the inside of the apparatus 40 is discharged through the discharge port 32 from the end of the discharge pipe 33. The supplied emulsion is further mixed by passing through the vibrating stirring and mixing device 40, and continuously cooled to a curing temperature of the solid oil component at 25 ° C or lower. In order to perform continuous cooling, it is preferable to provide a cooling jacket for circulating a cooling water on the outer side of the casing 41 to be described later in the vibrating stirring and mixing device, and from the side of the inflow port 31 on the vibrating stirring and mixing device 40. Four jackets 34, 35, 36, and 37 are sequentially mounted toward the discharge port 32 side. Cooling water is circulated in each jacket. The temperature of the cooling water can be appropriately set, and the supplied emulsion can be continuously or stepwise cooled from the side of the inflow port 31 toward the side of the discharge port 32 by the jacket.

2 is a schematic longitudinal cross-sectional view showing the vibratory stirring and mixing device 40. The device 40 is provided with a stirring body 44 composed of a drive shaft 42 and a stirring blade 43 attached to the drive shaft 42 in the tubular casing 41. The drive shaft 42 is connected to the vibrator 45a, and is configured to be vertically vibrated in the axial direction by the vibrator 45a.

The casing 41 is a tubular body having a circular cross section, and an inflow port 31 is provided near the lower portion thereof. A discharge port 32 is provided in the vicinity of the upper portion of the casing 41. The emulsified product that has flowed in from the inflow port 31 is mixed while being passed through the inside of the casing 41, is continuously cooled, and is discharged from the discharge port 32.

The agitating body 44 is disposed in the casing 41. The drive shaft 42 of the agitating body 44 extends in the longitudinal direction (longitudinal direction) of the casing 41. The upper end of the drive shaft 42 is coupled to the vibrator 45a via a joint 45b. The vibrator 45a is provided with a motor (not shown) and a known cam mechanism (not shown) connected to the output shaft. The cam mechanism is rotated by the The display is composed of a swinging portion (not shown). The rotating portion is eccentrically mounted to the output shaft of the motor. The swinging portion is swung by the eccentric rotation of the rotating portion. Then, the swing of the swinging portion is transmitted to the drive shaft 42 in the form of up and down vibration.

A ring-shaped partition portion 46 is provided in plural numbers on the inner wall of the casing 41. The compartments 46 have the same shape and protrude from the inner wall of the casing 41 in the horizontal direction. A drive shaft 42 is inserted into a circular hole formed in the center of the compartment portion 46. The diameter of the circular hole is larger than the diameter of the drive shaft 42. The inside of the casing 41 is divided into a plurality of mixing chambers 47 by the adjacent two compartments. The mixing chambers 47 are arranged in series along the longitudinal direction (longitudinal direction) of the casing 41.

3(a) and 3(b) are enlarged views of essential parts of the stirring body 44. The agitating body 44 is provided with a drive shaft 42 and a stirring blade 43 that is spirally attached to the circumferential surface thereof. In the same figure, the stirring blade 43 is attached in a spiral shape of 3 weeks. The agitating body 44 in this state is set as one set, and the stirring body 44 is arrange|positioned in each mixing chamber 47 in the housing. Therefore, the number of sets of the agitating body 44 is the same as the number of the mixing chambers 47. In the stirring body 44 of each group, the spiral direction of the stirring blade 43 is the same.

The agitating blades 43 of the respective agitating bodies 44 are provided with one or more openings 48 and/or one or more notches 49. The opening 48 and the notch 49 are designed such that when the agitating body 44 is viewed from the axial direction of the drive shaft 42 (see FIG. 3( a )), the positions at which the agitating blades adjacent to each other are not aligned with each other. The reason for this is to prevent short-circuit flow in the axial direction and to improve the stirring and mixing effect.

The vibrating stirring and mixing device 40 having the above configuration can be used, for example, in Japan. Patent Document No. 4-235729 or the like. Further, a commercially available product can also be used for the vibrating stirring and mixing device 40. Such a commercially available product is, for example, a device in which a cooling jacket is provided in a vibrating mixer (registered trademark) manufactured by Cold Chemical Industries, Ltd.

In the method of producing the fine particle dispersion using the production apparatus 100 having the above configuration, first, all the components constituting the target fine particle dispersion are filled in the mixing tank 211 of the first emulsification unit 21 of the emulsification unit 20 . Or a part thereof (the component filled in the mixing tank 211 contains water belonging to a dispersion medium). When a part of the components constituting the fine particle dispersion is filled, other components may be supplied from, for example, the high energy treatment unit 221 of the second emulsification unit 22 or the vibratory stirring and mixing device 40. In addition, when the first emulsification unit 21 is provided in two or more types, the first emulsification unit 21 on the upstream side may be filled with all of the components constituting the target fine particle dispersion, or may be successively performed in each of the first emulsification units 21. A part of the components constituting the target fine particle dispersion is filled. By filling a part of them one by one, it is possible to appropriately adjust the mixing conditions of the respective components and the like.

The component filled in the mixing tank 211 contains at least one or more oily components which are solid at 25 ° C. After the filling of the target component into the mixing tank 211 is completed, the mixing tank 211 is heated by the jacket 212 to make the oily component which is solid at 25 ° C into a molten state. Then, each component is mixed and dispersed by the stirring blade 213 in the mixing tank 211 to obtain a pre-emulsified product. The heating temperature can be appropriately set in accordance with the melting point of the solid fat. Generally, it is preferably set to be about 10 ° C higher than the melting point of the solid fat having the highest melting point.

After the ingredients filled in the mixing tank 211 are stirred and thoroughly mixed, they are turned on. The valve installed at the bottom of the mixing tank 211 is taken out, and the pre-emulsion in the mixing tank 211 is taken out. The pre-emulsion is supplied to the high-energy processing unit 221 of the second emulsification unit 22 via the tube 216.

In the high-energy treatment unit 221, a high-pressure emulsifier or an ultrasonic emulsifier is used to apply high energy to the pre-emulsified product obtained by the first emulsification unit 21 to obtain an emulsified product. The dropping energy applied by the high-pressure emulsifier or the ultrasonic emulsifier is preferably 5 × 10 ⁴ J/kg or more, more preferably 2 × 10 ⁵ J/kg or more from the viewpoint of reducing the particle diameter. The upper limit of the amount of energy dropped is not particularly limited, but the higher the energy to be dropped, the better. Here, "casting energy" means a value which can be calculated by the following formulas (1) to (3) in each emulsifier.

V=81.6d. Πd ² /4

In the formula, Q: volume flow rate, ΔP: operating pressure, ρ: density, V: micro-injection space volume, t: time, d: inner diameter.

Where p: density, W: output, A: amplifier area, V: mixing volume, t: time.

Where p: density, Np: number of powers, n: number of revolutions, d: blade diameter, V: volume of the mixture, t: time.

Further, the number of passes of the high-energy processing unit 221 is preferably one or more. When the high-energy processing unit 221 is passed through a plurality of times, it means the total total energy of the applied energy when the high-energy processing unit 221 passes.

After the target energy is dropped, the valve attached to the high-energy treatment unit 221 is opened, and the emulsion in the high-energy treatment unit 221 is taken out. The emulsion is supplied to the vibratory agitating and mixing device 40 via the tube 222. The migration time from the emulsification step (emulsion portion 20) to the cooling step (cooling portion 30) is preferably 60 seconds or less, more preferably 10 minutes from the viewpoint of preventing aggregation of the emulsion obtained in the emulsification portion 20. Within seconds. The lower limit of the migration time is not particularly limited, and the shorter the time, the better. The migration time from the emulsification unit 20 to the cooling unit 30 means that the emulsified product obtained by the second emulsification unit 22 passes through the tube 222 from the second emulsification unit 22 of the emulsification unit 20 and reaches the cooling unit 30 of the cooling unit 30. Time. The migration time is adjustable, for example, by the length of the tube 222.

In the vibrating stirring and mixing device 40, four jackets 34, 35, 36, and 37 for cooling jackets are attached as described above. The cooling jacket is covered with the cylindrical casing 41 shown in FIG. In a manner of being disposed outside the casing 41, cooling water of a predetermined temperature is circulated in each jacket, and heat exchange for cooling the fluid is performed by passing the emulsion obtained by the emulsification portion 20 through the casing 41. .

The total flow rate of the cooling water circulating in the cooling jacket is not particularly limited as long as the emulsion obtained by the emulsification portion 20 is efficiently cooled without being agglomerated, and the more preferable, the more preferable. Specifically, the total flow rate of the cooling water is preferably 10 times or more, more preferably 30 times or more, relative to the flow rate of the emulsion. Here, the "flow rate of the emulsion" means the flow rate when the emulsion obtained by the emulsification unit 20 passes through the inside of the casing 41. In addition, the "total flow rate of the cooling water" is a total flow rate of the flow rate of the cooling water circulating in each jacket when the four jackets 34, 35, 36, and 37 are provided as in the vibrating stirring and mixing device 40.

The temperature of the cooling water can be appropriately set, and the jacket can be used to cool the emulsion from the inflow port 31 side toward the discharge port 32 side continuously or in stages. In this case, the temperature of the cooling water flowing through the four jackets 34, 35, 36, 37 may gradually decrease from the inlet side to the outlet side of the agitating and mixing device 31, or may all be the same temperature.

In addition, the cooling water of the four jackets 34, 35, 36, and 37 is, for example, an emulsion flowing from the inflow port 31 side (upstream side) of the vibrating stirring and mixing device 40 toward the discharge port 32 side (downstream side). The emulsion is circulated from the upstream side toward the downstream side in accordance with the flow order of the emulsion, and may be circulated from the downstream side toward the upstream side in opposition to the flow of the emulsion.

In the vibrating stirring and mixing device 40, the agitating body 44 vibrates up and down in the axial direction thereof, and the emulsion in the casing 41 flows along the agitating body 44, and the passage through the stirring blade 43 is utilized. The flow of the opening 48 and the notch 49 is disordered so that it does not agglomerate and is further mixed. Therefore, the fine particles of the solid fat can be highly dispersed.

Then, if the emulsion is cooled by heat exchange with the cooling water, the fluidity is lowered. Since the emulsion is cooled by the flow along the agitating body 44 and by the flow of the opening 48 and the notch 49 provided in the agitating blade 43, the cooling is difficult to occur due to mixing and cooling. Further, since there is almost no dead space in the vibrating stirring and mixing device 40, the stirring unevenness is less likely to occur. The vibrating stirring and mixing device 40 can perform a good stirring and mixing regardless of whether the fluidity of the emulsion is high or low. These advantages of the vibrating stirring and mixing device 40 are preferable in that the emulsified particles having a solid oil (wax component or the like) contained in the emulsion are uniformly refined. Further, since the vibration type stirring and mixing device 40 has a small amount of heat generation, the cooling efficiency is excellent, and the emulsified particles can be rapidly cooled while being uniformly fined, so that the emulsified particles containing the solid fat can be well dispersed. The fact that the calorific value is small is also advantageous from the viewpoint of easier temperature control.

In this way, since the emulsion is cooled continuously to the curing temperature of the solid oil agent without being aggregated, it is possible to provide a fine particle dispersion having high productivity and excellent quality of the fine particle dispersion. The target dispersion is discharged from the discharge pipe 33 through the discharge port 32 of the vibratory stirring and mixing device 40. The target dispersion temperature in this state is about 30 °C.

When cooling using the vibratory stirring and mixing device 40, it is preferred to use an average cooling rate. It is set to 0.1 to 8 ° C / sec, more preferably 0.5 to 5 ° C / sec, and even more preferably set to 0.8 to 5 ° C / sec. The average cooling rate is a value obtained by dividing the temperature at which the fluid enters the vibratory stirring and mixing device 40 and the temperature difference at the time of exiting by the residence time. Further, the number of vibrations of the vibrating stirring and mixing device 40 is preferably in the range of 2.5 to 30 Hz, more preferably in the range of 5 to 25 Hz. The amplitude of the vibratory stirring and mixing device 40 is preferably 4 to 15 mm. Further, the total amount of vibration given during cooling by the vibratory stirring and mixing device 40 is preferably 50 to 100,000 strokes, more preferably 200 to 20,000 strokes.

The fine particle dispersion obtained by the production apparatus 100 in this manner has fluidity at 25° C., and includes, for example, a paste or a cream. Such a fine particle dispersion is applied to the ultraviolet defense cosmetic of the present invention. In the high-energy processing unit 221, the fine oil dispersion obtained by the manufacturing apparatus 100 is uniformly refined, and the solid oil agent is cooled and maintained in a state where the solid oil agent is uniformly and finely reduced in the cooling unit 30, so that the feeling of use is good. In particular, the makeup effect of reducing the stickiness and the ultraviolet protection effect is improved.

Further, the manufacturing method has been described based on the preferred embodiment, but is not limited thereto. For example, in the above embodiment, one type of the vibrating stirring and mixing device 40 is used, but instead of this, a plurality of vibrating stirring and mixing devices 40 may be used in series.

The ultraviolet-defining cosmetic of the present invention thus obtained is produced by the above steps, and thus contains fine emulsified particles. The volume median diameter of the emulsified particles is preferably 0.1 to 10 μm, more preferably 0.15 to 0.35 μm, and still more preferably 0.20 to 0.25 μm from the viewpoint of enhancing the ultraviolet protection effect and reducing the skin irritation.

Further, from the same viewpoint, the coefficient of variation of the emulsified particles is preferably 18 to 40, more preferably 19 to 30, and still more preferably 20 to 25. In addition, the "variation coefficient" means a numerical value obtained by dividing the standard deviation of the volume median diameter by the volume median diameter, and the lower the numerical value, the sharper the particle size distribution.

As described above, the ultraviolet-ray-protecting cosmetic of the present invention has a small particle size and a sharp particle size distribution, and this particle size distribution is considered to be one of the main causes of excellent storage stability, high ultraviolet protection effect, good feeling in use, and no skin irritation.

In the present invention, the volume median diameter is measured by a laser diffraction scattering method using a laser diffraction/scattering particle size distribution measuring apparatus (Model: LA-920, manufactured by Horiba, Ltd.).

The ultraviolet-ray protective cosmetic of the present invention can form, for example, a lotion, an emulsion, a cream, a gel, a cosmetic liquid, etc., and preferably forms a cream or a gel. Further, a sheet-like cosmetic material which is moistened or applied to a sheet-like substrate such as woven fabric or non-woven fabric may be formed.

The ultraviolet-defense cosmetic of the present invention can be used by being applied to the skin, preferably the scalp, and more preferably to the face, body, hands and feet.

Related to the above embodiments, the present invention further discloses the following invention.

<1> A UV-defense cosmetic containing the following components (A), (B), (C), (D), and (E): (A) an ionic surfactant 0.18 to 2% by mass, (B) 1 to 10% by mass of the hydrophobic amphiphilic substance, (C) 1 to 40% by mass of the liquid oil containing the oil-soluble ultraviolet absorber, (D) 0.01 to 6% by mass of the solid oil agent, (E) water The ultraviolet ray-protecting cosmetic material is obtained by a method comprising the steps of: emulsification step of forming an emulsion by mixing a composition containing the components (A) to (D) with (E) water under heating; The emulsion formed in the emulsification step is subjected to a cooling step of cooling at a cooling rate of 0.5 to 5 ° C / sec.

<2> The ultraviolet-ray protective cosmetic according to the above <1>, wherein the ionic surfactant of the component (A) is preferably an anionic surfactant, a cationic surfactant, an amphoteric surfactant, or a ceramide The salt thereof is more preferably selected from at least one of an anionic surfactant and a neuroamine alcohol, and more preferably an anionic surfactant, and more preferably a long-chain N-mercapto glutamate. Sodium lauryl glutamate, N-lauryl glutamic acid monosodium, N-stearyl sulfhydryl-L-glutamate, N-stearyl sulfhydryl-L-glutamic acid arginine, N - at least one selected from the group consisting of sodium stearyl glutamate and sodium N-myristyl-L-glutamate, and more preferably from N-stearyl glutamate, N-stearyl At least one of thiol-L-glutamic acid arginine is selected, and N-stearyl sulfhydryl-L-glutamic acid arginine is preferred.

<3> The ultraviolet-ray-protecting cosmetic composition of the above-mentioned <1> or <2>, wherein the content of the component (A) is preferably 0.2% by mass or more, more preferably 0.3% by mass or more, and more preferably the total content of the component (A). It is preferably 0.4% by mass or more, more preferably 0.45% by mass or more, and is preferably 1.5% by mass or less, more preferably 1.1% by mass or less, still more preferably 0.9% by mass or less, still more preferably 0.7% by mass or less.

(4) The ultraviolet-ray protective cosmetic according to any one of the above-mentioned items, wherein the content of the nonionic surfactant is preferably 1% by mass or less, more preferably, based on the total composition. 0.5% by mass or less, more preferably 0.1% by mass or less, and more preferably Mass 0% by mass.

The ultraviolet protective cosmetic according to any one of the above-mentioned items, wherein the hydrophobic amphiphilic substance of the component (B) is preferably a ceramide or a carbon number of 10~. 24 alcohol, linear saturated fatty acid having 10 to 24 carbon atoms, monoglyceride having 10 to 24 carbon atoms, monoalkyl glyceryl ether having 10 to 24 carbon atoms, and sorbitol having a carbon number of 10 to 24 At least one or two or more selected from the group consisting of an anhydride ester and a sorbitan ester of a single fatty acid having 10 to 24 carbon atoms, more preferably an alcohol having a carbon number of 14 to 22, a monoglyceride having a carbon number of 14 to 22, and a carbon number At least one or two or more selected from the group consisting of a monoalkyl glyceryl ether of 14 to 22 and a single fatty acid sorbitan ester having a carbon number of 14 to 22, and more preferably an alcohol having a carbon number of 16 to 22 and a carbon number of 16 to 22 The mono-fatty acid glyceride is more preferably one or more selected from the group consisting of cetyl alcohol, stearyl alcohol, and lipophilic mono-fatty acid glyceride.

The ultraviolet protective cosmetic according to any one of the above aspects, wherein the hydrophobic amphiphilic substance of the component (B) preferably contains an alcohol having 14 to 22 carbon atoms. Selecting at least one of a single fatty acid glyceride having 14 to 22 carbon atoms, a monoalkyl glyceryl ether having 14 to 22 carbon atoms, and a single fatty acid sorbitan ester having 14 to 22 carbon atoms, more preferably having a carbon number of 14 ~22 alcohol, and a single fatty acid glyceride having a carbon number of 14 to 22, and more preferably a carbon number 16 to 22 alcohol, a carbon number 16 to 22 single fatty acid glyceride, and more preferably a cetyl alcohol , stearyl alcohol, and a single fatty acid glyceride having a carbon number of 16-22.

The ultraviolet-ray-protecting cosmetic composition according to any one of the above-mentioned items, wherein the content of the component (B) is preferably 1.5% by mass or more, more preferably 2% by mass based on the total composition. % or more, more preferably 2.5% by mass or more, and more preferably 8% by mass or less, more preferably 5% by mass or less, still more preferably 3.8 mass% or less.

The ultraviolet-ray protective cosmetic according to any one of the above-mentioned items, wherein the oil-soluble ultraviolet absorber of the component (C) preferably contains p-methoxycinnamic acid-2- Ethylhexyl ester, octocrylene, 2,4,6-gin[4-(2-ethylhexyloxycarbonyl)anilino]-1,3,5-three , 4-tert-butyl-4'-methoxydibenzoylmethane, dimethoxybenzylidene dioxyimidazolium propionate-2-ethylhexyl ester, diethylaminohydroxybenzene Hexyl benzoyl benzoate, bisethylhexyl oxyphenol methoxyphenyl three One or more selected from the group consisting of p-methoxy cinnamic acid 2-ethylhexyl ester, diethylamino hydroxybenzoyl benzoic acid hexyl ester, and diethyl hexyl phenol Methoxyphenyl three One or more of them are selected, and more preferably, it contains p-methoxycinnamic acid-2-ethylhexyl ester, diethylaminohydroxybenzhydrylbenzoic acid hexyl ester, and bisethylhexyloxyphenol. Methoxyphenyl three .

The ultraviolet-ray-protecting cosmetic according to any one of the above-mentioned items, wherein the oil-soluble ultraviolet absorber is more preferably a cinnamic acid-based oil-soluble ultraviolet absorber or diethylaminohydroxybenzene. Hexyl methacrylate, three One or two or more of the oil-soluble ultraviolet absorbers are selected, and the three oil-soluble ultraviolet absorbers are particularly preferably contained, and more preferably, it contains 2-methoxyhexyl p-methoxycinnamate, and Amino hydroxybenzoyl benzoic acid hexyl ester, bisethylhexyl oxyphenol methoxyphenyl three .

The ultraviolet-ray protective cosmetic according to any one of the above-mentioned items, wherein the liquid oil agent other than the oil-soluble ultraviolet absorber preferably contains a linear or branched hydrocarbon oil. At least one of ester oil and polyoxygenated oil is selected.

The ultraviolet-ray-protecting cosmetic according to any one of the above-mentioned items, wherein the component (C) is preferably a total amount of the oil-soluble ultraviolet absorber in the total liquid oil. It is more than 5% by mass, more preferably 65% by mass or more, more preferably 70% by mass or more, more preferably 100% by mass or less, more preferably 90% by mass or less, and particularly excellent 85 mass% or less.

In the ultraviolet-ray-defending cosmetic according to any one of the above-mentioned items, the content of the oil-soluble ultraviolet absorber is preferably 6 in the total composition. The mass% or more, more preferably 8% by mass or more, still more preferably 10% by mass or more, and more preferably 20% by mass or less, more preferably 18% by mass or less, still more preferably 15% by mass or less.

The ultraviolet-ray-protecting cosmetic material of any one of the above-mentioned <1> to <12>, wherein the content of the cinnamic acid-based oil-soluble ultraviolet absorber is preferably 60% in the oil-soluble ultraviolet absorber. 100% by mass, more preferably 70 to 90% by mass.

(14) The ultraviolet-ray protective cosmetic according to any one of the above-mentioned <1> to <13>, wherein, among the oil-soluble ultraviolet absorbers, three The total content of the oil-soluble ultraviolet absorber and diethylhexyl hydroxybenzimidyl benzoate is preferably 0 to 40% by mass, more preferably 10 to 30% by mass.

The ultraviolet-ray-protecting cosmetic according to any one of the above-mentioned <1> to <14> wherein, in the oil-soluble ultraviolet absorber, the cinnamic acid-based oil-soluble ultraviolet absorber is compared with the third The ratio of the amount of the oil-soluble ultraviolet absorber to the diethylhexyl hydroxybenzoylbenzoic acid hexyl ester [cinnamic acid-based oil-soluble ultraviolet absorber / (three) It is an oil-soluble ultraviolet absorber + diethylhexyl hydroxybenzhydryl benzoate), preferably 9/1 to 5/5, more preferably 8.5/1.5 to 6/4, and more preferably 8 /2~6.5/3.5.

In the ultraviolet-ray-protecting cosmetic composition according to any one of the above-mentioned items, the content of the component (C) is preferably 3% by mass or more, more preferably 10% by mass based on the total composition. % or more, more preferably 12% by mass or more, and more preferably 35% by mass or less, more preferably 25% by mass or less, still more preferably 17% by mass or less.

<17> The ultraviolet-ray-protecting cosmetic according to any one of the above-mentioned items <1> to <16>, wherein the mass ratio [(A)/(C)] of the component (A) to the component (C) is compared. Preferably, it is 0.01 or more, more preferably 0.015 or more, still more preferably 0.025 or more, still more preferably 0.034 or more, and more preferably 0.2 or less, more preferably 0.12 or less, still more preferably 0.06 or less, and more preferably 0.05. the following.

<18> The ultraviolet-ray-protecting cosmetic according to any one of the above-mentioned items, wherein the ratio of the component (B) to the component (C) is higher than the mass ratio [(B)/(C)]. Preferably, it is 0.01 or more, more preferably 0.12 or more, still more preferably 0.18 or more, still more preferably 0.19 or more, and more preferably 0.5 or less, more preferably 0.39 or less, still more preferably 0.27 or less, and more preferably 0.24. the following.

The ultraviolet-ray protective cosmetic according to any one of the above-mentioned items, wherein the solid oil of the component (D) is preferably a solid oil having a melting point of 60 ° C or more and 80 ° C or less. More preferably, the agent contains one or more selected from the group consisting of ceresin and paraffin, and a solid oil having a melting point of 60 ° C or more and 80 ° C or less.

The ultraviolet-ray-protecting cosmetic according to any one of the above-mentioned items, wherein the content of the component (D) is in the total composition, preferably 0.08% by mass or more, more preferably 0.1. The mass% or more, more preferably 0.5% by mass or more, and more preferably 4.5% by mass or less, more preferably 2.5% by mass or less, still more preferably 1.5% by mass or less.

The ultraviolet-defense cosmetic according to any one of the above-mentioned items <1> to <20>, wherein the mass ratio [(D)/(C)] of the component (D) to the component (C) is compared. Preferably, it is 0.01 or more, more preferably 0.02 or more, still more preferably 0.04 or more, and is preferably 0.5 or less, more preferably 0.3 or less, still more preferably 0.1 or less.

In the ultraviolet-ray-protecting cosmetic composition according to any one of the above-mentioned items, the content of the component (E) is preferably 35 mass% or more, more preferably 45 mass, based on the total composition. % or more, and preferably 65% by mass or less, more preferably 55% by mass or less.

The ultraviolet-ray protective cosmetic according to any one of the above-mentioned items, further comprising (F) a water-soluble polymer.

<24> The ultraviolet-ray protective cosmetic according to the above <23>, wherein the component (F) is preferably an acrylic polymer, more preferably a carbomer, an acrylic/alkyl methacrylate copolymer, or a poly Acrylamide, (Na/propylene dimethyldimethyltaurate Na) copolymer, (hydroxyethyl acrylate/propylene dimethyldimethyltaurate) copolymer, (acrylamide/ammonium acrylate) At least one selected from the group consisting of copolymer and polyacrylate-13, particularly from (Na/acryloyldimethyl taurate Na) copolymer, (hydroxyethyl acrylate/acrylonitrile dimethyl cattle) At least one selected from the group consisting of a sulfonic acid Na) copolymer, a (acrylamide/ammonium acrylate) copolymer, and a polyacrylate-13.

<25> The ultraviolet-ray-defending cosmetic according to the above-mentioned <23> or <24>, wherein the content of the component (F) is preferably 0.3% by mass or more, more preferably 0.5% by mass or more, based on the total composition. It is preferably 1.5% by mass or less, more preferably 1.0% by mass or less.

The ultraviolet protection cosmetic according to any one of the above-mentioned items, wherein the emulsification step is preferably a homomixer, an ultrasonic emulsifier, or a high-pressure emulsifier, and is preferably heated. The mixed components are mixed at 60 to 120 ° C, more preferably 80 to 100 ° C.

The ultraviolet protection cosmetic according to any one of the above-mentioned items, wherein the cooling step is preferably a use of a vibrating stirring device or a scraper type heat exchanger. , static mixer, plate type heat exchanger, double The layered tube heat exchanger is subjected to a continuous rapid cooling method or a method of stirring and cooling in a general blending tank to perform cooling.

<28> The ultraviolet-ray-protecting cosmetic according to any one of the above-mentioned items, wherein the cooling rate is preferably 0.8 ° C /sec or more, and preferably 1.5 ° C / sec or less.

The ultraviolet-ray-protecting cosmetic material according to any one of the above-mentioned items, wherein the volume fraction of the emulsified particles is preferably 0.1 to 10 μm, more preferably 0.15 to 0.35 μm, and more preferably More preferably, it is 0.20 to 0.25 μm.

The ultraviolet-ray-defending cosmetic material of any one of the above-mentioned <1> to <29>, wherein the coefficient of variation of the emulsified particles is preferably 18 to 40, more preferably 19 to 30, and still more preferably 20 ~25.

<31> A UV-defense cosmetic according to any one of the above <1> to <30>, which is applied to the skin, preferably a scalp, preferably a face or a body. , hands and feet, etc.

<32> A method for producing a UV-defense cosmetic comprising: the following components (A), (B), (C), and (D): (A) an ionic surfactant 0.1 to 2% by mass (B) 1 to 10% by mass of the hydrophobic amphiphilic substance, (C) 1 to 40% by mass of the liquid oil containing the oil-soluble ultraviolet absorber, and (D) 0.01 to 6% by mass of the solid oil agent An emulsification step of mixing with (E) water under heating to form an emulsion; and an emulsion formed by the above emulsification step, at a cooling rate of 0.5 to 5 ° C / sec A cooling step for cooling.

[Examples] [Examples 1 to 29, Comparative Examples 1 to 5]

The ultraviolet-ray-protected cosmetics having the compositions shown in Tables 1 to 3 were prepared, and the volume median diameter and the coefficient of variation were measured, and the α gel and SPF values were confirmed, and the storage stability, the feeling of use, and the skin irritation were evaluated. The results are combined and summarized in Tables 1 to 3.

(Production method)

(1) Example 1:

A part of the components (A) to (D) and a component (E), propylene glycol, glycerin, arginine, and phenoxyethanol were dispersed by a homomixer at 85 ° C, and then a high-pressure emulsifier (manufactured by Sugino Machine Co., Ltd.) was used. , Star Burst minimo HJP-25001) obtained an emulsion. The number of passes (pass times) of the high-pressure emulsifier was set to 1 time. The emulsion was kept at 85 ° C, and supplied to a vibrating stirring and mixing device (manufactured by Cold Chemical Co., Ltd., a vibrating mixer) for 10 seconds according to the migration time, and stirred while the stirring body was vibrated up and down in the apparatus. The emulsion is continuously cooled to 40 ° C or lower (step (1)). Mixing the cooled emulsion with a mixture of the component (E), the component (F), and other components described in the table, and mixing at room temperature (25 ° C) (step (2) )), get UV protection cosmetics.

In the vibrating stirring and mixing device, the flow rate of the emulsion was 1 g/sec, and the total flow rate of the cooling water circulating in the cooling jacket was 10 g/sec, and the cooling water was cooled by a total flow rate of 10 times the flow rate of the emulsion. The average cooling rate at this time was 1 ° C/sec. Moreover, the vibration number of the vibrating stirring and mixing device is 20 Hz.

(2) Examples 2 to 28 and Comparative Examples 1 to 4:

The ultraviolet-ray protective cosmetics of Examples 2 to 28 and Comparative Examples 1 to 4 were obtained in the same manner as in Example 1.

(3) Example 29:

An emulsion was obtained in the same manner as in (1). The obtained emulsion was stirred in a container while using an anchor (rotation number: 75 rpm), and cooled to 40 ° C to obtain an ultraviolet defense cosmetic. The average cooling rate at this time was 1 ° C/sec.

(4) Comparative Example 5:

After the same emulsification step as in Example 1, the cooling step was carried out at a cooling rate of 0.01 ° C / sec in a temperature-controlled thermostatic chamber without stirring.

(evaluation method)

(1) Volume median particle size and coefficient of variation:

The volume-based median diameter and coefficient of variation were measured at a temperature of 25 ° C in accordance with a laser diffraction scattering method using a laser diffraction/scattering particle size distribution measuring apparatus (manufactured by Horiba, Ltd., model: LA-920). . The coefficient of variation is the standard deviation divided by the value of the particle size in the volume reference.

(2) Confirmation of alpha gel:

For each cosmetic, it was confirmed by XRD whether or not an α-gel structure was formed. Specifically, in the wide-angle X-ray diffraction, near the Bragg angle = 21 to 22 ° At least one cosmetic material having sharp diffraction peaks was judged to have an α-gel structure, and "α" was marked in the table.

(3) SPF value:

The PMMA plate was uniformly coated for 1 minute in a manner of 2 mg/cm ^{2 for} each cosmetic, and dried in a dark place for 15 minutes. After drying, an SPF analyzer (SPF 290S plus, manufactured by Optometricus USA) was used to measure the absorption spectrum (wavelength 350 nm) of the midpoint of each square, the apex, and the midpoint of the side connecting the vertices. Permeability (%), the average of 9 points. The result represents the SPF value (-) obtained from the penetration rate (%). (N=3)

(4) Preservation stability:

40 mL of the cosmetic was placed in a 50 mL glass bottle, sealed, and stored at -5 ° C for one month, and the appearance and fluidity of the preserved cosmetic were visually observed. The fluidity was visually confirmed to be fluid at a tilt of 45 °C. The baseline is as follows.

4: No change in appearance and / or fluidity.

3: Appearance and fluidity were found to be slightly changed.

2: At least one of appearance and fluidity found a slight change.

1: There is a large change in appearance (oil phase separation), or a large change in fluidity (gel-like change).

(5) Sense of use:

0.02 mL of each cosmetic was applied to a 3 cm-diameter circle on the inside of the forearm by five professional examiners, and extension coating was applied for 1 minute (25 ° C, 57 RH%). Then, make The feeling of feeling (stickiness) was rated as 5 at the time of no stickiness, and the condition of very sticky was rated as 1, and the evaluation was performed on the scale of 0.1, and the average score of 5 was obtained.

(6) Skin irritation:

0.02 mL of each cosmetic was applied to a 3 cm-diameter circle on the inside of the forearm by five professional examiners, and extension coating was applied for 1 minute (25 ° C, 57 RH%). Then, the irritating feeling was rated as 5 with no irritating feeling, and the case of very irritating sensation was rated as 1, and evaluated on the scale of 0.1, and the average score of 5 was obtained.

[Example 30]

The ultraviolet-ray protective cosmetics having the compositions shown in Table 4 were produced in the same manner as in Examples 1 to 28.

The ultraviolet-ray-protected cosmetic obtained was obtained by dispersing emulsified particles having a volume median diameter of 0.22 μm, and an α gel was confirmed.

Further, the oil agent containing the ultraviolet absorber is uniformly dispersed, excellent in storage stability, high in ultraviolet protection effect, non-sticky, good in feeling of use, and free from skin irritation.

[Example 31]

UV-defense of the composition shown in Table 5 was produced in the same manner as in Examples 1 to 28. Makeup material.

The ultraviolet-ray-protected cosmetic obtained was obtained by dispersing emulsified particles having a volume median diameter of 0.24 μm, and an α gel was confirmed.

Further, the oil agent containing the ultraviolet absorber is uniformly dispersed, excellent in storage stability, high in ultraviolet protection effect, non-sticky, good in feeling of use, and free from skin irritation.

[Examples 32 to 34, Comparative Example 6]

The ultraviolet-ray protective cosmetics having the compositions shown in Table 6 were produced in the same manner as in Examples 1 to 28, and the volume median diameter and the coefficient of variation were measured to confirm the α gel and the SPF value. Evaluation of preservation stability, feeling of use and skin irritation. The results are combined and summarized in Table 6.

Further, when the cosmetics of Examples 32 to 34 and Comparative Example 6 were produced, the cooling rate was as shown in Table 6.

[Example 35 and Comparative Example 7]

The ultraviolet-ray protective cosmetics having the compositions shown in Table 7 were produced in the same manner as in Examples 1 to 28, and the transdermal absorbability of the ultraviolet absorber was evaluated.

Evaluation of transdermal absorbability of UV absorbers

Test sequence

The test sequence is as follows. The human excised skin which was cryopreserved at -80 ° C was thawed at room temperature for about 30 minutes, and after removing excess fat from the skin, it was cut into about 2 cm square and used for measurement. A skin test sample was used for the penetration test.

The penetration test was carried out using a Franz-type diffusion tank (a formulation use area of 1 cm ² and a receptor phase of 16 mL). 10 μL of the prepared sample was placed in the donor phase and kept at 37 ° C for 24 hours. After 24 hours, after cleanly removing the sample on the skin surface with purified water, the epidermis was separated from the dermis. Ultrasonic treatment was carried out for 20 minutes using 5 mL of methanol, and the concentration of the ultraviolet absorber was measured by a UV-visible spectrophotometer UV3600 (Shimadzu Corporation) after filtration using a membrane filter (PTFE 0.45 μm ADVANTEC).

test results

The transdermal absorbability was evaluated against the samples of Table 7. The results are shown in Table 8 below.

It was found that the sample of Example 35 containing the ultraviolet absorber contained in the sample of Comparative Example 7 containing no ultraviolet absorber significantly reduced the transdermal absorbability of the ultraviolet absorber.

20‧‧‧Emulsifying Department

21‧‧‧1st Emulsifying Department

22‧‧‧2nd Emulsifying Department

30‧‧‧ Cooling Department

31‧‧‧Inlet

32‧‧‧Exporting

33‧‧‧Spit tube

34, 35, 36, 37‧‧ ‧ jacket

40‧‧‧Vibrating mixing and mixing device

41‧‧‧Shell

100‧‧‧ manufacturing equipment

211‧‧‧ mixing tank

212‧‧‧ Jacket

213‧‧‧Agitating blades

214‧‧‧Axis

215‧‧‧ motor

216‧‧‧ tube

221‧‧‧High Energy Processing Department

222‧‧‧ tube

Claims (8)

An ultraviolet defense cosmetic containing the following components (A), (B), (C), (D) and (E): (A) ionic surfactant 0.18-2% by mass; (B) hydrophobic 1 to 10% by mass of the amphiphilic substance; (C) 1 to 40% by mass of the liquid oil containing the oil-soluble ultraviolet absorber; (D) 0.01 to 6% by mass of the solid oil; (E) water; The method comprises the steps of: emulsification step of mixing the composition containing the components (A) to (D) with (E) water under heating to form an emulsion; and forming the emulsion formed by the emulsification step The cooling step is performed at a cooling rate of 0.5 to 5 ° C / sec. The ultraviolet-defense cosmetic of claim 1, which further contains (F) a water-soluble polymer. The ultraviolet-defense cosmetic of claim 1, wherein the mass ratio (A)/(C) of the component (A) to the component (C) is 0.01 to 0.2. The ultraviolet-defense cosmetic of claim 1, wherein the mass ratio (B)/(C) of the component (B) to the component (C) is 0.01 to 0.5. The ultraviolet-defense cosmetic of claim 1, wherein the mass ratio (D)/(C) of the component (D) to the component (C) is 0.01 to 0.5. The ultraviolet-defense cosmetic of claim 1, which further contains (F) a water-soluble polymer. The ultraviolet defense cosmetic according to any one of claims 1 to 6, wherein the emulsified granule The volume median diameter of the sub-unit is 0.1 to 10 μm. A method for producing a UV-defense cosmetic material, comprising: mixing a composition containing the following components (A), (B), (C), and (D) with (E) water under heating to form an emulsion; And an emulsification step; and a cooling step of cooling the emulsion formed by the emulsification step at a cooling rate of 0.5 to 5 ° C / sec; (A) 0.1 to 2% by mass of the ionic surfactant; (B) hydrophobicity The amphiphilic substance is 1 to 10% by mass; (C) the liquid oil containing the oil-soluble ultraviolet absorber is 1 to 40% by mass; and (D) the solid oil is 0.01 to 6% by mass.