TW201604195A - 神經激酶-１拮抗劑之靜脈注射劑型 - Google Patents
神經激酶-１拮抗劑之靜脈注射劑型 Download PDFInfo
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- TW201604195A TW201604195A TW104121014A TW104121014A TW201604195A TW 201604195 A TW201604195 A TW 201604195A TW 104121014 A TW104121014 A TW 104121014A TW 104121014 A TW104121014 A TW 104121014A TW 201604195 A TW201604195 A TW 201604195A
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- solutol
- hemolysis
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Classifications
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
- A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
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| US23412909P | 2009-08-14 | 2009-08-14 |
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| TW099127158A TWI498329B (zh) | 2009-08-14 | 2010-08-13 | 神經激酶－１拮抗劑之靜脈注射劑型 |
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| EP (2) | EP3143996A1 (https=) |
| JP (2) | JP5860399B2 (https=) |
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| CN (2) | CN102573475B (https=) |
| AU (1) | AU2010282483B2 (https=) |
| BR (1) | BR112012003263A2 (https=) |
| CA (1) | CA2770403C (https=) |
| ES (1) | ES2609640T3 (https=) |
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| SG (2) | SG10201407538WA (https=) |
| TW (2) | TW201604195A (https=) |
| WO (1) | WO2011019911A1 (https=) |
Cited By (1)
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| TWI853965B (zh) * | 2019-06-28 | 2024-09-01 | 大陸商上海盛迪醫藥有限公司 | 神經激肽-1拮抗劑 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2662374A1 (en) * | 2006-04-05 | 2013-11-13 | OPKO Health, Inc. | Salts of 8-[{1-(3,5-bis-(trifluoromethyl) phenyl) -ethoxy}-methyl]-8-phenyl-1,7 -diaza-spiro[4.5]decan-2-one and preparation process therefor |
| SG10201500028RA (en) | 2006-04-05 | 2015-02-27 | Opko Health Inc | Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same |
| AR066191A1 (es) | 2007-03-22 | 2009-08-05 | Schering Corp | Proceso e intermediarios para la sintesis de compuestos 8- [ ( 1- (3,5- bis- ( trifluorometil) fenil) - etoxi ) - metil]- 8 fenil - 1,7- diaza - espiro (4, 5) decan -2 ona |
| KR101719004B1 (ko) | 2008-09-05 | 2017-03-22 | 옵코 헬스, 인크. | 8-［｛1-（3,5-비스-（트리플루오로메틸）페닐）-에톡시｝-메틸］-8-페닐-1,7-디아자-스피로［4.5］데칸-2-온 화합물의 합성 방법 및 중간체 |
| CN102573475B (zh) | 2009-08-14 | 2016-01-20 | 欧科生医股份有限公司 | 神经激肽-1拮抗剂的静脉内制剂 |
| AR097683A1 (es) * | 2013-09-26 | 2016-04-06 | Lilly Co Eli | Compuestos y uso para la preparación de agentes de formación de imagen tau y formulaciones para la formación de imagen tau |
| WO2016044784A1 (en) | 2014-09-19 | 2016-03-24 | Heron Therapeutics, Inc. | Emulson formulations of aprepitant |
| CA2978736C (en) | 2015-03-04 | 2023-11-07 | Vanda Pharmaceuticals Inc. | Dosing regimen of tradipitant |
| US20180250270A1 (en) | 2015-09-11 | 2018-09-06 | Chase Pharmaceuticals Corporation | Muscarinic combination and its use for combating hypocholinergic disorders of the central nervous system |
| US9974742B2 (en) * | 2016-02-01 | 2018-05-22 | Heron Therapeutics, Inc. | Emulsion formulations of an NK-1 receptor antagonist and uses thereof |
| KR20180118136A (ko) * | 2016-02-01 | 2018-10-30 | 헤론 테라퓨틱스 인코포레이티드 | Nk-1 수용체 길항제를 포함하는 에멀젼 |
| US20190175702A1 (en) * | 2016-08-03 | 2019-06-13 | Zhuhai Beihai Biotech Co., Ltd. | Formulations of fosaprepitant and aprepitant |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI853965B (zh) * | 2019-06-28 | 2024-09-01 | 大陸商上海盛迪醫藥有限公司 | 神經激肽-1拮抗劑 |
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| EP2464230B1 (en) | 2016-10-05 |
| US20160024092A1 (en) | 2016-01-28 |
| MX2012001872A (es) | 2012-04-11 |
| US9101615B2 (en) | 2015-08-11 |
| RU2642234C2 (ru) | 2018-01-24 |
| JP2013501806A (ja) | 2013-01-17 |
| JP2016041734A (ja) | 2016-03-31 |
| EP3143996A1 (en) | 2017-03-22 |
| JP6308991B2 (ja) | 2018-04-11 |
| AU2010282483B2 (en) | 2014-09-04 |
| CN102573475B (zh) | 2016-01-20 |
| TWI498329B (zh) | 2015-09-01 |
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| EP2464230A1 (en) | 2012-06-20 |
| MX336071B (es) | 2016-01-06 |
| EP2464230A4 (en) | 2013-01-02 |
| TW201111382A (en) | 2011-04-01 |
| WO2011019911A1 (en) | 2011-02-17 |
| SG10201407538WA (en) | 2015-01-29 |
| US20110038925A1 (en) | 2011-02-17 |
| CN105503870A (zh) | 2016-04-20 |
| RU2012109405A (ru) | 2013-09-20 |
| ES2609640T3 (es) | 2017-04-21 |
| BR112012003263A2 (pt) | 2015-09-22 |
| JP5860399B2 (ja) | 2016-02-16 |
| AU2010282483A1 (en) | 2012-03-01 |
| CN102573475A (zh) | 2012-07-11 |
| IL217942A0 (en) | 2012-03-29 |
| CA2770403A1 (en) | 2011-02-17 |
| SG178403A1 (en) | 2012-03-29 |
| KR101834577B1 (ko) | 2018-03-05 |
| CA2770403C (en) | 2020-09-01 |
| RU2017145628A (ru) | 2019-02-19 |
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