TW201326194A - Ｇｌｐ－１胃泌素受體促效劑肽結合物 - Google Patents

Ｇｌｐ－１胃泌素受體促效劑肽結合物 Download PDF

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Publication number
TW201326194A
TW201326194A TW101140873A TW101140873A TW201326194A TW 201326194 A TW201326194 A TW 201326194A TW 101140873 A TW101140873 A TW 101140873A TW 101140873 A TW101140873 A TW 101140873A TW 201326194 A TW201326194 A TW 201326194A
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TW
Taiwan
Prior art keywords
8ado
pharmaceutically acceptable
glu
solvate
disease
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TW101140873A
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English (en)
Chinese (zh)
Inventor
Trine Skovlund Neerup
Jakob Lind Tolborg
Keld Fosgerau
Torben Oesterlund
Dorthe Lennert Almholt
Lone Larsen
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Zealand Pharma As
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Publication of TW201326194A publication Critical patent/TW201326194A/zh

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • C—CHEMISTRY; METALLURGY
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
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TW101140873A 2011-11-03 2012-11-02 Ｇｌｐ－１胃泌素受體促效劑肽結合物 TW201326194A (zh)

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US201161555435P 2011-11-03 2011-11-03

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US (2) US9259477B2 (cg-RX-API-DMAC7.html)
EP (1) EP2773377B1 (cg-RX-API-DMAC7.html)
JP (1) JP6359972B2 (cg-RX-API-DMAC7.html)
KR (1) KR20140100947A (cg-RX-API-DMAC7.html)
CN (1) CN104144704B (cg-RX-API-DMAC7.html)
AR (1) AR088636A1 (cg-RX-API-DMAC7.html)
AU (1) AU2012331053A1 (cg-RX-API-DMAC7.html)
BR (1) BR112014010780A2 (cg-RX-API-DMAC7.html)
CA (1) CA2853884A1 (cg-RX-API-DMAC7.html)
EA (1) EA028951B9 (cg-RX-API-DMAC7.html)
MX (1) MX2014005351A (cg-RX-API-DMAC7.html)
TW (1) TW201326194A (cg-RX-API-DMAC7.html)
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AU2012331053A1 (en) 2011-11-03 2014-05-29 Zealand Pharma A/S GLP-1 receptor agonist peptide gastrin conjugates
EA035688B1 (ru) 2013-11-06 2020-07-27 Зилэнд Фарма А/С Соединения, которые представляют собой тройные агонисты глюкагона, glp-1 и gip
EP3065767B1 (en) 2013-11-06 2020-12-30 Zealand Pharma A/S Gip-glp-1 dual agonist compounds and methods
AU2015340586B2 (en) 2014-10-29 2020-04-30 Zealand Pharma A/S GIP agonist compounds and methods
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
EP3426678B1 (en) * 2016-03-10 2025-07-02 Shenzhen Hightide Biopharmaceutical, Ltd. Conjugates of islet neogenesis peptides and analogs, and methods thereof
KR102502040B1 (ko) 2016-12-09 2023-02-24 질랜드 파마 에이/에스 아실화 glp-1/glp-2 이중 효능제
CA3067674A1 (en) * 2017-06-29 2019-01-03 Ureka Sarl Pro-drug peptide with improved pharmaceutical properties
CN109248323B (zh) * 2017-07-14 2023-09-08 杭州先为达生物科技有限公司 酰化的glp-1衍生物
CN109331173B (zh) * 2018-12-17 2021-05-07 中国医学科学院医学实验动物研究所 胃泌素-二氧化硅微球及其用途
CN112759640B (zh) * 2020-12-09 2023-09-08 江苏师范大学 一类glp-1/胃泌素受体双重激动剂及其应用
GB202308304D0 (en) * 2023-06-02 2023-07-19 Univ Ulster A fusion peptide for activation of the apj and/or glp-1 receptors

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