TW201309343A - 經改善親水性藥物之藥物移行性之水性組成物 - Google Patents

經改善親水性藥物之藥物移行性之水性組成物 Download PDF

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Publication number
TW201309343A
TW201309343A TW101104139A TW101104139A TW201309343A TW 201309343 A TW201309343 A TW 201309343A TW 101104139 A TW101104139 A TW 101104139A TW 101104139 A TW101104139 A TW 101104139A TW 201309343 A TW201309343 A TW 201309343A
Authority
TW
Taiwan
Prior art keywords
aqueous composition
drug
acid
present
hydrophilic drug
Prior art date
Application number
TW101104139A
Other languages
English (en)
Chinese (zh)
Inventor
稻垣孝司
堀部吉偉
中田雄一郎
Original Assignee
參天製藥股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 參天製藥股份有限公司 filed Critical 參天製藥股份有限公司
Publication of TW201309343A publication Critical patent/TW201309343A/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
TW101104139A 2011-02-10 2012-02-09 經改善親水性藥物之藥物移行性之水性組成物 TW201309343A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011027431 2011-02-10

Publications (1)

Publication Number Publication Date
TW201309343A true TW201309343A (zh) 2013-03-01

Family

ID=46638701

Family Applications (1)

Application Number Title Priority Date Filing Date
TW101104139A TW201309343A (zh) 2011-02-10 2012-02-09 經改善親水性藥物之藥物移行性之水性組成物

Country Status (3)

Country Link
JP (1) JP2012180346A (ja)
TW (1) TW201309343A (ja)
WO (1) WO2012108489A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101748057B1 (ko) * 2012-11-19 2017-06-15 보오슈 앤드 롬 인코포레이팃드 2-아미노-3-(4-브로모벤조일)페닐아세트산을 함유하는 수성 액체 조성물
ES2875307T3 (es) 2014-01-10 2021-11-10 Santen Pharmaceutical Co Ltd Composición farmacéutica que contiene un compuesto derivado del ácido piridilaminoacético
JP2022063252A (ja) * 2020-10-09 2022-04-21 千寿製薬株式会社 ブリモニジンの液体製剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions
SE9401108D0 (sv) * 1994-03-31 1994-03-31 Leiras Oy Ophthalmic composition I
JPH11130675A (ja) * 1997-08-29 1999-05-18 Santen Pharmaceut Co Ltd クロマン誘導体含有点眼液
WO2003082257A2 (en) * 2002-03-28 2003-10-09 Sucampo Ag Method for treating ocular hypertension and glaucoma
JP5382972B2 (ja) * 2003-12-26 2014-01-08 ロート製薬株式会社 粘度低下が防止された組成物
JP5301069B2 (ja) * 2004-04-15 2013-09-25 ロート製薬株式会社 アズレン含有水性液剤
JP2008266143A (ja) * 2007-04-16 2008-11-06 Santen Pharmaceut Co Ltd アデノシン誘導体を有効成分として含有する緑内障治療剤

Also Published As

Publication number Publication date
WO2012108489A1 (ja) 2012-08-16
JP2012180346A (ja) 2012-09-20

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