TW200829232A - Method of treating asthma, allergic rhinitis, and skin disorders - Google Patents

Method of treating asthma, allergic rhinitis, and skin disorders Download PDF

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Publication number
TW200829232A
TW200829232A TW096141830A TW96141830A TW200829232A TW 200829232 A TW200829232 A TW 200829232A TW 096141830 A TW096141830 A TW 096141830A TW 96141830 A TW96141830 A TW 96141830A TW 200829232 A TW200829232 A TW 200829232A
Authority
TW
Taiwan
Prior art keywords
formula
compound
alkyl
cycloalkyl
phenyl
Prior art date
Application number
TW096141830A
Other languages
English (en)
Chinese (zh)
Inventor
Peter G Klimko
Clay Beauregard
Bryon S Severns
Original Assignee
Alcon Mfg Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Mfg Ltd filed Critical Alcon Mfg Ltd
Publication of TW200829232A publication Critical patent/TW200829232A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
TW096141830A 2006-11-07 2007-11-06 Method of treating asthma, allergic rhinitis, and skin disorders TW200829232A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85733906P 2006-11-07 2006-11-07

Publications (1)

Publication Number Publication Date
TW200829232A true TW200829232A (en) 2008-07-16

Family

ID=39276163

Family Applications (1)

Application Number Title Priority Date Filing Date
TW096141830A TW200829232A (en) 2006-11-07 2007-11-06 Method of treating asthma, allergic rhinitis, and skin disorders

Country Status (12)

Country Link
US (2) US20080108695A1 (cg-RX-API-DMAC7.html)
EP (1) EP2079459A2 (cg-RX-API-DMAC7.html)
JP (1) JP2010509240A (cg-RX-API-DMAC7.html)
KR (1) KR20090086573A (cg-RX-API-DMAC7.html)
CN (1) CN101534806A (cg-RX-API-DMAC7.html)
AU (1) AU2007316482A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0718540A2 (cg-RX-API-DMAC7.html)
CA (1) CA2668645A1 (cg-RX-API-DMAC7.html)
MX (1) MX2009004962A (cg-RX-API-DMAC7.html)
TW (1) TW200829232A (cg-RX-API-DMAC7.html)
WO (1) WO2008058098A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200902909B (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7687539B1 (en) * 2005-11-07 2010-03-30 Alcon Research, Ltd. Method of treating ocular allergy
WO2011096941A1 (en) * 2010-02-08 2011-08-11 Alcon Research, Ltd. Method of treating ocular allergy
CA2788333A1 (en) * 2010-02-25 2011-09-01 Alcon Research, Ltd. Method of accelerating corneal wound healing
CN110840878B (zh) * 2019-11-05 2020-06-26 牡丹江医学院 一种用于治疗银屑病的化合物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286730A (en) * 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory disease
FR2701477B1 (fr) * 1993-02-16 1995-03-31 Adir Nouveaux composés (cyclohexyl)alcéniques, leurs procédés de préparation, et les compositions pharmaceutiques qui les contiennent.
US6887901B1 (en) * 1993-06-15 2005-05-03 Brigham & Women's Hospital, Inc. Lipoxin compounds and their use in treating cell proliferative disorders
EP1657233A1 (en) * 1993-06-15 2006-05-17 The Brigham & Women's Hospital, Inc. Lipoxin compounds
US5430049A (en) * 1993-12-08 1995-07-04 Gaut; Zane N. Treating hyperproliferative disorders
SE9601677D0 (sv) * 1996-05-02 1996-05-02 Scotia Lipidteknik Ab New use
US6831186B2 (en) * 2001-11-06 2004-12-14 Schering Aktiengesellschft Lipoxin A4 analogs
US8815950B2 (en) * 2003-08-29 2014-08-26 Janssen Biotech, Inc. Pharmaceutical compositions and method of using levodopa and carbidopa
US20050203184A1 (en) * 2003-09-10 2005-09-15 Petasis Nicos A. Benzo lipoxin analogues
DE602005020178D1 (de) * 2004-11-09 2010-05-06 Alcon Inc 5,6,7-trihydroxyheptansäure und analoge zur behandlung von augenkrankheiten und mit hyperproliferativen und angiogenen reaktionen verbundenen krankheiten

Also Published As

Publication number Publication date
WO2008058098A3 (en) 2008-08-07
WO2008058098A2 (en) 2008-05-15
US20080108695A1 (en) 2008-05-08
MX2009004962A (es) 2009-05-21
AU2007316482A1 (en) 2008-05-15
CA2668645A1 (en) 2008-05-15
JP2010509240A (ja) 2010-03-25
CN101534806A (zh) 2009-09-16
US20090156667A1 (en) 2009-06-18
KR20090086573A (ko) 2009-08-13
ZA200902909B (en) 2010-07-28
EP2079459A2 (en) 2009-07-22
BRPI0718540A2 (pt) 2013-11-19

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