TW200640882A - Compounds - Google Patents
CompoundsInfo
- Publication number
- TW200640882A TW200640882A TW095106363A TW95106363A TW200640882A TW 200640882 A TW200640882 A TW 200640882A TW 095106363 A TW095106363 A TW 095106363A TW 95106363 A TW95106363 A TW 95106363A TW 200640882 A TW200640882 A TW 200640882A
- Authority
- TW
- Taiwan
- Prior art keywords
- oro
- halo
- group
- rac
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65619305P | 2005-02-25 | 2005-02-25 | |
GBGB0503962.3A GB0503962D0 (en) | 2005-02-25 | 2005-02-25 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200640882A true TW200640882A (en) | 2006-12-01 |
Family
ID=34430242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095106363A TW200640882A (en) | 2005-02-25 | 2006-02-24 | Compounds |
Country Status (6)
Country | Link |
---|---|
US (1) | US7504397B2 (zh) |
CN (1) | CN101128440A (zh) |
BR (1) | BRPI0607915A2 (zh) |
GB (1) | GB0503962D0 (zh) |
TW (1) | TW200640882A (zh) |
ZA (1) | ZA200706673B (zh) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010509370A (ja) * | 2006-11-10 | 2010-03-25 | シンダックス ファーマシューティカルズ,インク. | 癌の治療用のERα+リガンドとヒストンデアセチラーゼ阻害剤との組み合わせ |
WO2008103636A1 (en) * | 2007-02-20 | 2008-08-28 | Novartis Ag | Imidazoquinolines as dual lipid kinase and mtor inhibitors |
FR2915747B1 (fr) * | 2007-05-04 | 2011-02-25 | Scras | Derives de tri-amino-pyrimidine comme inhibiteurs de phosphatase cdc25 |
US20090131367A1 (en) * | 2007-11-19 | 2009-05-21 | The Regents Of The University Of Colorado | Combinations of HDAC Inhibitors and Proteasome Inhibitors |
EP2250160B1 (en) | 2008-01-25 | 2015-11-11 | Millennium Pharmaceuticals, Inc. | Thiophenes and their use as phosphatidylinositol 3-kinase (pi3k) inhibitors |
US20110053907A1 (en) * | 2008-03-27 | 2011-03-03 | Auckland Uniservices Limited | Substituted pyrimidines and triazines and their use in cancer therapy |
CL2009000844A1 (es) * | 2008-04-11 | 2009-06-12 | Galaxy Biotech Llc | Metodo para tratar cancer en un paciente que comprende la administracion de un primer agente que es inhibidor de factor de crecimiento de hepatocito (hgf) en combinacion con un segundo agente que es agonista de pten. |
CN102256966B (zh) * | 2008-10-17 | 2016-02-10 | 白头生物医学研究所 | 可溶性mTOR复合物和其调节剂 |
CA2750935A1 (en) | 2009-01-30 | 2010-08-12 | Millennium Pharmaceuticals, Inc. | Heteroaryls and their use as pi3k inhibitors |
US8796314B2 (en) | 2009-01-30 | 2014-08-05 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
US9090601B2 (en) | 2009-01-30 | 2015-07-28 | Millennium Pharmaceuticals, Inc. | Thiazole derivatives |
AR077999A1 (es) * | 2009-09-02 | 2011-10-05 | Vifor Int Ag | Antagonistas de pirimidin y triazin-hepcidina |
WO2011039735A2 (en) * | 2009-10-02 | 2011-04-07 | Consiglio Nazionale Delle Ricerche | Compounds with ddx3 inhibitory activity and uses thereof |
US20130195919A1 (en) | 2010-03-05 | 2013-08-01 | President And Fellows Of Harvard College | Induced dendritic cell compositions and uses thereof |
WO2011111051A1 (en) | 2010-03-11 | 2011-09-15 | Yeda Research And Development Co. Ltd. | Death associated protein 1 variants and use thereof for modulating autophagy |
WO2012021615A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
PE20131304A1 (es) | 2010-08-11 | 2013-11-14 | Millennium Pharm Inc | Heteroarilos y sus usos |
WO2012021611A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
TW201307309A (zh) | 2010-10-13 | 2013-02-16 | Millennium Pharm Inc | 雜芳基化合物及其用途 |
WO2013154778A1 (en) | 2012-04-11 | 2013-10-17 | Dana-Farber Cancer Institute, Inc. | Host targeted inhibitors of dengue virus and other viruses |
KR101761464B1 (ko) | 2012-05-23 | 2017-07-25 | 에프. 호프만-라 로슈 아게 | 내배엽 및 간세포를 수득하고 사용하는 조성물 및 방법 |
WO2014026997A1 (de) | 2012-08-16 | 2014-02-20 | Bayer Pharma Aktiengesellschaft | 2,3-benzodiazepine |
US10000483B2 (en) | 2012-10-19 | 2018-06-19 | Dana-Farber Cancer Institute, Inc. | Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof |
AU2014293011A1 (en) | 2013-07-26 | 2016-03-17 | Race Oncology Ltd. | Compositions to improve the therapeutic benefit of bisantrene |
WO2015016195A1 (ja) | 2013-07-29 | 2015-02-05 | 協和発酵キリン株式会社 | Wntシグナル阻害剤 |
BR112016018691A2 (pt) * | 2014-02-14 | 2017-08-08 | Univ British Columbia | Compostos do domínio de ligação ao dna (dbd) de receptor de andrógeno humano como terapêuticos e métodos para seu uso |
KR20160127826A (ko) | 2014-03-24 | 2016-11-04 | 에이비 사이언스 | 비장 티로신 키나제 억제제로서 치환된 옥사졸 유도체 |
CN104130256B (zh) * | 2014-08-01 | 2016-08-24 | 上海毕得医药科技有限公司 | 一种吡啶并[3,4-d]嘧啶-4(3H)-酮衍生物的制备方法 |
US9987241B2 (en) | 2014-09-25 | 2018-06-05 | The Board Of Regents Of The University Of Oklahoma | Enzyme conjugate and prodrug cancer therapy |
EP3144307A1 (en) | 2015-09-18 | 2017-03-22 | AB Science | Novel oxazole derivatives that inhibit syk |
US11446365B2 (en) | 2017-08-09 | 2022-09-20 | The Board Of Regents Of The University Of Oklahoma | Antimalarial enzyme conjugates, kits containing same, and methods of producing and using same |
CN109438438A (zh) * | 2018-12-30 | 2019-03-08 | 苏州大学 | 一种苯丙咪唑类化合物及其制备方法和应用 |
CN110713487B (zh) * | 2019-10-10 | 2022-02-15 | 南京大学 | 一种新型杂环芳腙类衍生物、其药学上可接受的盐、其制备方法和应用 |
US20230135152A1 (en) * | 2020-02-11 | 2023-05-04 | AcuraStem Incorporated | Pikfyve kinase inhibitors |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3601196A1 (de) | 1986-01-17 | 1987-07-23 | Merck Patent Gmbh | 1,4-dihydropyridine |
US6335339B1 (en) | 1998-01-13 | 2002-01-01 | Scriptgen Pharmaceuticals, Inc. | Triazine antiviral compounds |
FI20000577A0 (fi) | 2000-03-13 | 2000-03-13 | Orion Yhtymae Oy | Pyridatsinyylifenyylihydratsoneja |
US6660737B2 (en) | 2001-05-04 | 2003-12-09 | The Procter & Gamble Company | Medicinal uses of hydrazones |
GB0121488D0 (en) * | 2001-09-05 | 2001-10-24 | Smithkline Beecham Plc | Compounds |
US7223759B2 (en) | 2003-09-15 | 2007-05-29 | Anadys Pharmaceuticals, Inc. | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds |
-
2005
- 2005-02-25 GB GBGB0503962.3A patent/GB0503962D0/en not_active Ceased
-
2006
- 2006-02-24 US US11/361,599 patent/US7504397B2/en not_active Expired - Fee Related
- 2006-02-24 TW TW095106363A patent/TW200640882A/zh unknown
- 2006-02-24 BR BRPI0607915-6A patent/BRPI0607915A2/pt not_active IP Right Cessation
- 2006-02-24 CN CNA2006800061259A patent/CN101128440A/zh active Pending
-
2007
- 2007-08-10 ZA ZA200706673A patent/ZA200706673B/en unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0607915A2 (pt) | 2011-10-18 |
US20060199804A1 (en) | 2006-09-07 |
CN101128440A (zh) | 2008-02-20 |
GB0503962D0 (en) | 2005-04-06 |
ZA200706673B (en) | 2008-07-30 |
US7504397B2 (en) | 2009-03-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200640882A (en) | Compounds | |
WO2006090167A3 (en) | Hydrazinomethyl, hydr zonomethyl and 5-membered heterocylic compounds which act as mtor inhibitors and their use as anti cancer agents | |
TW200407309A (en) | 1,2-Azole derivatives | |
NO20071873L (no) | DNA-PK inhibotorer. | |
TW200728914A (en) | A salt suitable for an acid generator and a chemically amplified resist composition containing the same | |
TW200632551A (en) | A salt suitable for an acid generator and a chemically amplified resist composition containing the same | |
NZ599040A (en) | 2,4-disubstituted pyrido[4,3-d]pyrimidin-5(6h)-one compounds for selective inhibitors of lrrk2 and syk kinases | |
MY152972A (en) | Azabicyclo compound and salt thereof | |
MX2012008391A (es) | Derivados de piridina di-sustituida como agentes anticancer. | |
MY153045A (en) | Oxopyrazine derivative and herbicide | |
ECSP12012212A (es) | Derivados de ariletinilo | |
EA200601847A1 (ru) | Замещённые метиларил- или гетероариламидные соединения | |
TW200726760A (en) | Chemical compounds IV | |
TN2011000422A1 (en) | Benzofuran derivatives | |
UA95978C2 (ru) | Ингибитор активации stat3/5 | |
ZA200601595B (en) | Aminopyrones and their use as ATM inhibitors | |
HK1069827A1 (en) | Pyranones useful as atm inhibitors. | |
PH12018501733A1 (en) | Pyridazinone compound or its salt, and herbicide containing it | |
IN2014CN02843A (zh) | ||
TW200637870A (en) | Novel pyrimidine nucleoside compound and salt thereof | |
MX2013007938A (es) | Compuesto biciclico novedoso o sal del mismo. | |
HK1078586A1 (en) | Carbacyclic phosphatidic acid derivative | |
RS54120B1 (en) | Pyridinyl-I pyrazinyl-methyloxyaryl derivatives USED AS INHIBITORS OF TYROSINE KINASE TREATMENT (SYK) | |
MX2009006552A (es) | Derivados de 4-(1-amino-etil)-ciclohexilamina. | |
MY152795A (en) | Surfactant composition |