TW200640474A - Tricyclic-nucleoside compounds for treating viral infections - Google Patents

Tricyclic-nucleoside compounds for treating viral infections

Info

Publication number
TW200640474A
TW200640474A TW095106861A TW95106861A TW200640474A TW 200640474 A TW200640474 A TW 200640474A TW 095106861 A TW095106861 A TW 095106861A TW 95106861 A TW95106861 A TW 95106861A TW 200640474 A TW200640474 A TW 200640474A
Authority
TW
Taiwan
Prior art keywords
viral infections
tricyclic
treating viral
nucleoside compounds
compounds
Prior art date
Application number
TW095106861A
Other languages
English (en)
Chinese (zh)
Inventor
Jesse Daniel Keicher
Christopher Don Roberts
Sebastian Johannes Reinhard Liehr
xiao-ling Zheng
Marija Prhavc
Vivek Kumar Rajwanshi
Ronald Conrad Griffith
Choung U Kim
Original Assignee
Genelabs Tech Inc
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genelabs Tech Inc, Gilead Sciences Inc filed Critical Genelabs Tech Inc
Publication of TW200640474A publication Critical patent/TW200640474A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/22Pteridine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW095106861A 2005-02-28 2006-03-01 Tricyclic-nucleoside compounds for treating viral infections TW200640474A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65746305P 2005-02-28 2005-02-28

Publications (1)

Publication Number Publication Date
TW200640474A true TW200640474A (en) 2006-12-01

Family

ID=36570903

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095106861A TW200640474A (en) 2005-02-28 2006-03-01 Tricyclic-nucleoside compounds for treating viral infections

Country Status (18)

Country Link
US (4) US7524825B2 (https=)
EP (2) EP1853618A1 (https=)
JP (2) JP2008531704A (https=)
KR (2) KR20070106767A (https=)
CN (2) CN101142226A (https=)
AP (2) AP2007004128A0 (https=)
AR (1) AR058419A1 (https=)
AU (2) AU2006218705A1 (https=)
BR (2) BRPI0607770A2 (https=)
CA (2) CA2597685A1 (https=)
EA (2) EA200701849A1 (https=)
HR (2) HRP20070436A2 (https=)
IL (2) IL184954A0 (https=)
MX (2) MX2007010460A (https=)
NO (2) NO20074613L (https=)
TW (1) TW200640474A (https=)
WO (2) WO2006093986A1 (https=)
ZA (1) ZA200707410B (https=)

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KR20140064765A (ko) 2011-06-30 2014-05-28 스텔라 에이피에스 Hcv 조합 치료
WO2013033093A1 (en) * 2011-08-29 2013-03-07 Biocryst Pharmaceuticals, Inc. Heterocyclic compounds as janus kinase inhibitors
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Also Published As

Publication number Publication date
EA200701849A1 (ru) 2008-02-28
EA200701850A1 (ru) 2008-02-28
US20060194749A1 (en) 2006-08-31
JP2008531703A (ja) 2008-08-14
EP1853618A1 (en) 2007-11-14
US20090253648A1 (en) 2009-10-08
AP2007004118A0 (en) 2007-08-31
WO2006093986A1 (en) 2006-09-08
KR20070106767A (ko) 2007-11-05
ZA200707410B (en) 2008-10-29
MX2007010460A (es) 2007-11-08
WO2006093987A1 (en) 2006-09-08
NO20074915L (no) 2007-11-20
AP2007004128A0 (en) 2007-08-31
AR058419A1 (es) 2008-02-06
NO20074613L (no) 2007-11-27
CN101142226A (zh) 2008-03-12
CN101128474A (zh) 2008-02-20
JP2008531704A (ja) 2008-08-14
MX2007010463A (es) 2007-11-08
US7534771B2 (en) 2009-05-19
IL184954A0 (en) 2007-12-03
CA2597683A1 (en) 2006-09-08
CA2597685A1 (en) 2006-09-08
HRP20070436A2 (hr) 2008-02-29
HRP20070435A9 (en) 2008-09-30
EP1853617A1 (en) 2007-11-14
HRP20070435A2 (hr) 2008-02-29
BRPI0607769A2 (pt) 2009-10-06
US20090208457A1 (en) 2009-08-20
IL184955A0 (en) 2007-12-03
KR20070106781A (ko) 2007-11-05
BRPI0607770A2 (pt) 2009-06-13
AU2006218705A1 (en) 2006-09-08
US20060252715A1 (en) 2006-11-09
AU2006218704A1 (en) 2006-09-08
US7524825B2 (en) 2009-04-28

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