TW200607810A - Process to prepare camptothecin derivatives - Google Patents

Process to prepare camptothecin derivatives

Info

Publication number
TW200607810A
TW200607810A TW094117529A TW94117529A TW200607810A TW 200607810 A TW200607810 A TW 200607810A TW 094117529 A TW094117529 A TW 094117529A TW 94117529 A TW94117529 A TW 94117529A TW 200607810 A TW200607810 A TW 200607810A
Authority
TW
Taiwan
Prior art keywords
camptothecin derivatives
prepare
prepare camptothecin
derivatives
irinotecan
Prior art date
Application number
TW094117529A
Other languages
English (en)
Inventor
Ragina Naidu
Original Assignee
Phytogen Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200607810(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Phytogen Life Sciences Inc filed Critical Phytogen Life Sciences Inc
Publication of TW200607810A publication Critical patent/TW200607810A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
TW094117529A 2004-05-28 2005-05-27 Process to prepare camptothecin derivatives TW200607810A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/857,170 US20050267141A1 (en) 2004-05-28 2004-05-28 Process to prepare camptothecin derivatives

Publications (1)

Publication Number Publication Date
TW200607810A true TW200607810A (en) 2006-03-01

Family

ID=34971729

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094117529A TW200607810A (en) 2004-05-28 2005-05-27 Process to prepare camptothecin derivatives

Country Status (8)

Country Link
US (2) US20050267141A1 (zh)
EP (1) EP1791539B2 (zh)
CN (1) CN101022805A (zh)
AT (1) ATE440605T1 (zh)
CA (1) CA2568523A1 (zh)
DE (1) DE602005016282D1 (zh)
TW (1) TW200607810A (zh)
WO (1) WO2005117879A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050267141A1 (en) 2004-05-28 2005-12-01 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives
US20050272757A1 (en) * 2004-06-04 2005-12-08 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives and novel intermediate and compounds thereof
US7910737B2 (en) 2005-02-07 2011-03-22 Fermion Oy Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin
ES2430375T3 (es) 2005-02-08 2013-11-20 Fermion Oy Procedimiento para la producción de cloruro de [1,4']bipiperidinil-1'-carbonilo o su clorhidrato
PL1928883T3 (pl) 2005-02-08 2014-03-31 Fermion Oy Sposób otrzymywania chlorowodorku irynotekanu
US8138343B2 (en) 2007-06-25 2012-03-20 Scinopharm Taiwan Ltd. Crystalline polymorph of 7-ethyl-10-hydroxycamptothecin
CN101337966B (zh) * 2007-07-06 2011-05-18 江苏恒瑞医药股份有限公司 一种制备高纯度伊立替康的方法
US8993309B2 (en) * 2008-03-31 2015-03-31 Boston Medical Center Corporation Predictive marker for topoisomerase I inhibitors
US11467158B2 (en) 2012-10-29 2022-10-11 Boston Medical Center Corporation BRCA1 mutations as predictive markers for topoisomerase inhibitions

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399282A (en) * 1979-07-10 1983-08-16 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives
US4399276A (en) * 1981-01-09 1983-08-16 Kabushiki Kaisha Yakult Honsha 7-Substituted camptothecin derivatives
US4473692A (en) * 1981-09-04 1984-09-25 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
JPS6019790A (ja) 1983-07-14 1985-01-31 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
US5004758A (en) 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
US5391571A (en) 1989-11-15 1995-02-21 American Home Products Corporation Cholesterol ester hydrolase inhibitors
US5112859A (en) 1990-09-14 1992-05-12 American Home Products Corporation Biphenyl amide cholesterol ester hydrolase inhibitors
ES2137932T3 (es) 1990-09-28 2000-01-01 Smithkline Beecham Corp Procedimiento para la preparacion de analogos de camptotecina solubles en agua, asi como los compuestos 10-hidroxi-11-alcoxi-6-camptotecina.
JPH06502642A (ja) 1990-10-31 1994-03-24 スミスクライン・ビーチャム・コーポレイション 置換インドリジノ［１，２−ｂ］キノリノン
TW438775B (en) * 1995-04-07 2001-06-07 Pharmacia & Upjohn Co Llc Novel intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds
HUP0101511A3 (en) 1998-04-28 2002-12-28 Dainippon Pharmaceutical Co 1-[(1-substituted-4-piperidinyl)methyl]-4-piperidine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
US6043367A (en) * 1998-09-30 2000-03-28 Roffler; Steve Proactive antitumor compounds
JP2002193911A (ja) 2000-10-28 2002-07-10 Pfizer Prod Inc グルココルチコイドレセプターモジュレーター
DE10250082A1 (de) 2002-10-25 2004-05-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
US20050267141A1 (en) 2004-05-28 2005-12-01 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives
US20050272757A1 (en) 2004-06-04 2005-12-08 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives and novel intermediate and compounds thereof

Also Published As

Publication number Publication date
ATE440605T1 (de) 2009-09-15
WO2005117879A1 (en) 2005-12-15
CN101022805A (zh) 2007-08-22
CA2568523A1 (en) 2005-12-15
DE602005016282D1 (de) 2009-10-08
US20050267141A1 (en) 2005-12-01
EP1791539B2 (en) 2012-11-21
EP1791539A1 (en) 2007-06-06
US8592588B2 (en) 2013-11-26
US20080280935A1 (en) 2008-11-13
EP1791539B1 (en) 2009-08-26

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