TW200605870A - Topical methadone compositions and methods for using the same - Google Patents
Topical methadone compositions and methods for using the sameInfo
- Publication number
- TW200605870A TW200605870A TW094113586A TW94113586A TW200605870A TW 200605870 A TW200605870 A TW 200605870A TW 094113586 A TW094113586 A TW 094113586A TW 94113586 A TW94113586 A TW 94113586A TW 200605870 A TW200605870 A TW 200605870A
- Authority
- TW
- Taiwan
- Prior art keywords
- methods
- compositions
- same
- methadone
- topical
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- USSIQXCVUWKGNF-UHFFFAOYSA-N 6-(dimethylamino)-4,4-diphenylheptan-3-one Chemical compound C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 USSIQXCVUWKGNF-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001797 methadone Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Botany (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56668604P | 2004-04-29 | 2004-04-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200605870A true TW200605870A (en) | 2006-02-16 |
Family
ID=35393974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW094113586A TW200605870A (en) | 2004-04-29 | 2005-04-28 | Topical methadone compositions and methods for using the same |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20050244486A1 (enExample) |
| EP (1) | EP1740162A4 (enExample) |
| JP (1) | JP5250257B2 (enExample) |
| KR (1) | KR20070007850A (enExample) |
| CN (1) | CN1976689A (enExample) |
| AR (1) | AR048878A1 (enExample) |
| AU (2) | AU2005244214B2 (enExample) |
| BR (1) | BRPI0510428A (enExample) |
| CA (1) | CA2563489C (enExample) |
| CR (1) | CR8722A (enExample) |
| EA (1) | EA011423B1 (enExample) |
| IL (1) | IL178661A0 (enExample) |
| ME (1) | MEP25008A (enExample) |
| MX (1) | MXPA06012563A (enExample) |
| NO (1) | NO20065455L (enExample) |
| NZ (1) | NZ550963A (enExample) |
| RS (1) | RS20060605A (enExample) |
| TW (1) | TW200605870A (enExample) |
| UA (1) | UA88464C2 (enExample) |
| WO (1) | WO2005110381A1 (enExample) |
| ZA (1) | ZA200608923B (enExample) |
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| ES2499067T3 (es) * | 2005-10-13 | 2014-09-26 | Nitto Denko Corporation | Preparación transdérmica de nicotina y método de producción de la misma |
| US20080220062A1 (en) * | 2006-10-23 | 2008-09-11 | Psivida, Inc. | Sustained release of agents for localized pain management |
| JP5704801B2 (ja) * | 2008-08-21 | 2015-04-22 | ニプロパッチ株式会社 | 粘着性組成物及び経皮吸収型製剤 |
| GB2481619B (en) * | 2010-06-30 | 2012-06-20 | Londonpharma Ltd | Formulations and delivery devices for the sublingual administration of opioids |
| WO2014037832A2 (en) | 2012-09-06 | 2014-03-13 | Mahesh Kandula | Compositions and methods for the treatment of epilepsy and neurological diseases |
| SG11201407300VA (en) | 2012-05-07 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of neurological disorders |
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| WO2013167990A1 (en) | 2012-05-07 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of depression |
| WO2013167993A1 (en) | 2012-05-08 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of neurological degenerative disorders |
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| WO2013168004A2 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of fibromyalgia pain |
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| WO2013168001A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of moderate to severe pain |
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| WO2013168000A1 (en) * | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of severe pain |
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| WO2013175376A2 (en) | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of local pain |
| US9108942B1 (en) | 2014-11-05 | 2015-08-18 | Mahesh Kandula | Compositions and methods for the treatment of moderate to severe pain |
| WO2014020480A2 (en) | 2012-08-03 | 2014-02-06 | Mahesh Kandula | Compositions and methods for the treatment migraine and neurologic diseases |
| WO2014037833A2 (en) | 2012-09-06 | 2014-03-13 | Mahesh Kandula | Compositions and methods for the treatment inflammation and lipid disorders |
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| US9096537B1 (en) | 2014-12-31 | 2015-08-04 | Mahesh Kandula | Compositions and methods for the treatment of mucositis |
| CA2976314C (en) | 2014-09-26 | 2021-02-23 | Cellix Bio Private Limited | Compositions and methods for the treatment of epilepsy and neurological disorders |
| CA2967908C (en) | 2014-09-29 | 2020-11-17 | Mahesh Kandula | Compositions and methods for the treatment of multiple sclerosis |
| JP6564868B2 (ja) | 2014-10-27 | 2019-08-21 | セリックス バイオ プライヴェート リミテッドCellix Bio Private Limited | 多発性硬化症の治療のための、フマル酸モノメチルエステルとピペラジン又はエチレンジアミンとの3つの成分の塩 |
| US9290486B1 (en) | 2014-11-05 | 2016-03-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of epilepsy |
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| US9321716B1 (en) | 2014-11-05 | 2016-04-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic syndrome |
| US9173877B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of local pain |
| US9932294B2 (en) | 2014-12-01 | 2018-04-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
| US9206111B1 (en) | 2014-12-17 | 2015-12-08 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological diseases |
| CN110845355A (zh) | 2015-01-06 | 2020-02-28 | 塞尔利克斯生物私人有限公司 | 用于治疗炎症和疼痛的组合物和方法 |
| US20240068023A1 (en) * | 2021-01-14 | 2024-02-29 | The Trustees Of Indiana University | Methods to predict effects of perioperative administration of methadone to optimize pain relief and avoid adverse effects |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5316759A (en) * | 1986-03-17 | 1994-05-31 | Robert J. Schaap | Agonist-antagonist combination to reduce the use of nicotine and other drugs |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| EP0399432B1 (en) * | 1989-05-25 | 1994-06-22 | Takeda Chemical Industries, Ltd. | Transdermal therapeutic composition |
| US5580876A (en) * | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| WO1994010987A1 (en) * | 1992-11-09 | 1994-05-26 | Pharmetrix Corporation | Combined analgesic delivery methods for pain management |
| US5883115A (en) * | 1992-11-09 | 1999-03-16 | Pharmetrix Division Technical Chemicals & Products, Inc. | Transdermal delivery of the eutomer of a chiral drug |
| US5589480A (en) * | 1994-08-17 | 1996-12-31 | Elkhoury; George F. | Topical application of opioid analgesic drugs such as morphine |
| US5948389A (en) * | 1995-06-07 | 1999-09-07 | El Khoury & Stein, Ltd. | Method of enhancing the analgesic efficacy of locally and topically administered opioids and other local anesthetics |
| US5947921A (en) * | 1995-12-18 | 1999-09-07 | Massachusetts Institute Of Technology | Chemical and physical enhancers and ultrasound for transdermal drug delivery |
| US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| DE19642043A1 (de) * | 1995-10-23 | 1997-04-24 | Hexal Ag | Transdermales therapeutisches System (TTS) für die Verabreichung von Wirkstoffen zur Behandlung von Drogenabhängigkeit oder Drogensucht |
| US6787149B1 (en) * | 1996-12-12 | 2004-09-07 | El Khoury And Stein Ltd. | Topical application of opioid analgesic drugs such as morphine |
| WO1999015210A2 (en) * | 1997-09-26 | 1999-04-01 | Noven Pharmaceuticals, Inc. | Bioadhesive compositions and methods for topical administration of active agents |
| US6143278A (en) * | 1998-02-23 | 2000-11-07 | Elkhoury; George F. | Topical application of opioid analgesic drugs such as morphine |
| GB9804885D0 (en) * | 1998-03-06 | 1998-04-29 | Merck Sharp & Dohme | Therapeutic combination |
| CA2320900C (en) * | 1998-03-19 | 2009-10-27 | Bristol-Myers Squibb Company | Biphasic controlled release delivery system for high solubility pharmaceuticals and method |
| DE19850517B4 (de) * | 1998-11-03 | 2004-02-12 | Lts Lohmann Therapie-Systeme Ag | Verwendung eines wirkstoffhaltigen transdermalen therapeutischen Systems in einer Kombinationsbehandlung mit und ohne Ultraschall |
| GB9828480D0 (en) * | 1998-12-24 | 1999-02-17 | Dermatech Limited | Transdermal drug delivery system |
| US6383471B1 (en) * | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| US6720001B2 (en) * | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
| US20020004065A1 (en) * | 2000-01-20 | 2002-01-10 | David Kanios | Compositions and methods to effect the release profile in the transdermal administration of active agents |
| US6716449B2 (en) * | 2000-02-08 | 2004-04-06 | Euro-Celtique S.A. | Controlled-release compositions containing opioid agonist and antagonist |
| AU2001235284A1 (en) * | 2000-02-22 | 2001-09-03 | Cellegy Canada Inc. | Methods and compositions for improving sleep |
| US6638981B2 (en) * | 2001-08-17 | 2003-10-28 | Epicept Corporation | Topical compositions and methods for treating pain |
| US6796429B2 (en) * | 2001-10-22 | 2004-09-28 | 3M Innovative Properties Company | Transdermal/transmucosal patch packaging |
| US6713470B2 (en) * | 2002-01-22 | 2004-03-30 | Ml Laboratories Plc | Method of treatment |
-
2005
- 2005-04-26 NZ NZ550963A patent/NZ550963A/en not_active IP Right Cessation
- 2005-04-26 US US11/115,968 patent/US20050244486A1/en not_active Abandoned
- 2005-04-26 ME MEP-250/08A patent/MEP25008A/xx unknown
- 2005-04-26 WO PCT/US2005/014240 patent/WO2005110381A1/en not_active Ceased
- 2005-04-26 BR BRPI0510428-9A patent/BRPI0510428A/pt not_active IP Right Cessation
- 2005-04-26 CN CNA2005800219605A patent/CN1976689A/zh active Pending
- 2005-04-26 UA UAA200611217A patent/UA88464C2/ru unknown
- 2005-04-26 RS RSP-2006/0605A patent/RS20060605A/sr unknown
- 2005-04-26 EP EP05757678A patent/EP1740162A4/en not_active Ceased
- 2005-04-26 JP JP2007510880A patent/JP5250257B2/ja not_active Expired - Fee Related
- 2005-04-26 CA CA2563489A patent/CA2563489C/en not_active Expired - Fee Related
- 2005-04-26 KR KR1020067022347A patent/KR20070007850A/ko not_active Ceased
- 2005-04-26 ZA ZA200608923A patent/ZA200608923B/en unknown
- 2005-04-26 AU AU2005244214A patent/AU2005244214B2/en not_active Ceased
- 2005-04-26 EA EA200601776A patent/EA011423B1/ru not_active IP Right Cessation
- 2005-04-26 MX MXPA06012563A patent/MXPA06012563A/es unknown
- 2005-04-28 AR ARP050101672A patent/AR048878A1/es unknown
- 2005-04-28 TW TW094113586A patent/TW200605870A/zh unknown
-
2006
- 2006-10-16 IL IL178661A patent/IL178661A0/en unknown
- 2006-11-02 CR CR8722A patent/CR8722A/es not_active Application Discontinuation
- 2006-11-27 NO NO20065455A patent/NO20065455L/no not_active Application Discontinuation
-
2010
- 2010-04-29 AU AU2010201707A patent/AU2010201707A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EA200601776A1 (ru) | 2007-04-27 |
| MEP25008A (en) | 2010-10-10 |
| CA2563489C (en) | 2013-06-18 |
| JP2007538008A (ja) | 2007-12-27 |
| IL178661A0 (en) | 2007-02-11 |
| JP5250257B2 (ja) | 2013-07-31 |
| ZA200608923B (en) | 2008-05-28 |
| WO2005110381A1 (en) | 2005-11-24 |
| KR20070007850A (ko) | 2007-01-16 |
| UA88464C2 (ru) | 2009-10-26 |
| AU2005244214A1 (en) | 2005-11-24 |
| CR8722A (es) | 2007-05-30 |
| AU2010201707A1 (en) | 2010-05-20 |
| NO20065455L (no) | 2007-01-19 |
| CA2563489A1 (en) | 2005-11-24 |
| US20050244486A1 (en) | 2005-11-03 |
| RS20060605A (sr) | 2008-09-29 |
| EP1740162A1 (en) | 2007-01-10 |
| BRPI0510428A (pt) | 2007-10-30 |
| NZ550963A (en) | 2008-11-28 |
| MXPA06012563A (es) | 2007-03-21 |
| AR048878A1 (es) | 2006-06-07 |
| AU2005244214B2 (en) | 2010-02-18 |
| CN1976689A (zh) | 2007-06-06 |
| EP1740162A4 (en) | 2009-11-18 |
| EA011423B1 (ru) | 2009-02-27 |
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