TR201906372T4 - Nano taşıyıcılara ait formülasyonlar ve bunların hazırlanmasına ilişkin yöntemler. - Google Patents

Nano taşıyıcılara ait formülasyonlar ve bunların hazırlanmasına ilişkin yöntemler. Download PDF

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Publication number
TR201906372T4
TR201906372T4 TR2019/06372T TR201906372T TR201906372T4 TR 201906372 T4 TR201906372 T4 TR 201906372T4 TR 2019/06372 T TR2019/06372 T TR 2019/06372T TR 201906372 T TR201906372 T TR 201906372T TR 201906372 T4 TR201906372 T4 TR 201906372T4
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TR
Turkey
Prior art keywords
solution
nanocarriers
mixture
drug
formulations
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TR2019/06372T
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English (en)
Inventor
Doshi Manish
Sherdiwala Divyesh
Sojitra Prakash
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Concept Medical Res Private Limited
Envision Scient Private Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Concept Medical Res Private Limited, Envision Scient Private Limited filed Critical Concept Medical Res Private Limited
Publication of TR201906372T4 publication Critical patent/TR201906372T4/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/624—Nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Nano taşıyıcıların hazırlanmasına yönelik bir yöntem ifşa edilmektedir. Yöntem, bir ilaca ait bir organik çözelti ve bir biyolojik maddeye ait bir organik çözelti bir veya daha fazla çözünmüş yüzey aktif maddeye yer veren önceden belirlenmiş bir miktardaki suyla ayrı ayrı karıştırılarak sırasıyla birinci bir karışımın ve ikinci bir karışımın elde edilmesini içermektedir. Daha sonra, birinci karışım ve ikinci karışım ayrı ayrı homojenleştirilerek sırasıyla ilacın nano kristallerine ait bir çözelti ve biyolojik maddenin nano parçacıklarına ait bir çözelti elde edilmektedir. Ardından, ilacın nano kristallerine ait çözelti ve biyolojik maddenin nano parçacıklarına ait çözelti bir ultrasonlu homojenleştirme işlemine birlikte tabi tutularak nano taşıyıcılara ait bir çözelti elde edilmektedir. Daha sonra, nano taşıyıcılara ait çözelti üzerinde bir ara yüzey ekstraksiyonu ve/veya bir diyaliz gerçekleştirilerek nano taşıyıcılar elde edilmektedir. Nano taşıyıcılara ait formülasyonlar da ifşa edilmektedir.
TR2019/06372T 2010-01-18 2011-01-06 Nano taşıyıcılara ait formülasyonlar ve bunların hazırlanmasına ilişkin yöntemler. TR201906372T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN133MU2010 2010-01-18

Publications (1)

Publication Number Publication Date
TR201906372T4 true TR201906372T4 (tr) 2019-05-21

Family

ID=44304741

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/06372T TR201906372T4 (tr) 2010-01-18 2011-01-06 Nano taşıyıcılara ait formülasyonlar ve bunların hazırlanmasına ilişkin yöntemler.

Country Status (9)

Country Link
US (1) US20120321670A1 (tr)
EP (1) EP2525782B1 (tr)
CA (1) CA2786671A1 (tr)
DK (1) DK2525782T3 (tr)
ES (1) ES2726952T3 (tr)
PL (1) PL2525782T3 (tr)
PT (1) PT2525782T (tr)
TR (1) TR201906372T4 (tr)
WO (1) WO2011086574A2 (tr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3002989C (en) 2013-10-14 2021-03-16 Nanosphere Health Sciences, Llc Nanoparticle compositions and methods as carriers of nutraceutical factors across cell membranes and biological barriers
WO2016044482A1 (en) * 2014-09-17 2016-03-24 Vivacelle Bio, Inc. Stable micelle and/or liposome compositions and uses thereof
CA3050535C (en) 2014-12-15 2021-11-09 Richard Clark Kaufman Methods of treating inflammatory disorders and global inflammation with compositions comprising phospholipid nanoparticle encapsulations of anti-inflammatory nutraceuticals
CN104586817A (zh) * 2015-02-11 2015-05-06 苏州大学 一种多西他赛固体脂质纳米粒冻干制剂及其制备方法
AU2015385825A1 (en) 2015-03-10 2017-10-05 Nanosphere Health Sciences, Llc Lipid nanoparticle compositions and methods as carriers of cannabinoids in standardized precision-metered dosage forms
KR20210114409A (ko) 2018-12-11 2021-09-23 디스럽션 랩스 인코퍼레이티드 치료제 전달용 조성물과 이의 이용 및 제조 방법
WO2021194772A1 (en) 2020-03-27 2021-09-30 Boston Scientific Scimed, Inc. Methods for crystallization of drugs
CN111671982A (zh) * 2020-05-08 2020-09-18 北京永益润成科技有限公司 一种药物涂层组合物及其制备方法
CN114886855B (zh) * 2022-05-19 2023-10-03 北京柏欧利诺生物科技有限公司 一种雷公藤红素纳米药物及其制备方法

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
US20040208877A1 (en) * 2002-07-01 2004-10-21 Avigdor Levanon Antibodies and uses thereof
AU2003287526A1 (en) * 2002-11-06 2004-06-03 Protein-stabilized liposomal formulations of pharmaceutical agents
US7767219B2 (en) * 2003-01-31 2010-08-03 Boston Scientific Scimed, Inc. Localized drug delivery using drug-loaded nanocapsules
CN1493361A (zh) * 2003-08-29 2004-05-05 上海医药工业研究院 山榆酸甘油酯的脂质纳米粒及其制备方法
JP2007526322A (ja) * 2004-03-02 2007-09-13 マサチューセッツ インスティテュート オブ テクノロジー ナノセル薬物送達系
BRPI0600275A (pt) * 2006-01-03 2007-10-02 Brz Biotecnologia Ltda prótese coronária liberadora de composição medicamentosa para prevenção e tratamento da reestenose e processo de fabricação
US20090110739A1 (en) * 2007-05-15 2009-04-30 University Of North Texas Health Science Center At Forth Worth Targeted cancer chemotherapy using synthetic nanoparticles
DE102007061624A1 (de) * 2007-05-31 2009-06-25 Ernst-Moritz-Arndt-Universität Greifswald Verfahren zur Beschichtung von Oberflächen mit Mikro- und Nanopartikeln mit Hilfe von Plasmaverfahren und dessen Verwendung
CN101167699A (zh) * 2007-11-28 2008-04-30 厦门大学 胰岛素口服缓释制剂及其制备方法
US8343497B2 (en) * 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
RU2605793C2 (ru) * 2009-05-29 2016-12-27 Энвижн Сайентифик Прайвит Лимитед ВОССТАНОВЛЕНИЕ КРОВОТОКА В ЗАБЛОКИРОВАННЫХ АРТЕРИЯХ ЧЕЛОВЕКА ПУТЕМ ПЕРЕНОСА НАНОИНКАПСУЛИРОВАННОГО ЛЕКАРСТВЕННОГО СРЕДСТВА ПОСРЕДСТВОМ МЕДИЦИНСКИХ УСТРОЙСТВ, РАЗРАБОТАННЫХ ДЛЯ ЭТОГО, И ВЫСВОБОЖДЕНИЯ НАНОИНКАПСУЛИРОВАННОГО ЛЕКАРСТВЕННОГО СРЕДСТВА В АРТЕРИИ ЧЕЛОВЕКА ПРИ УРОВНЕ pH ОРГАНИЗМА
CN102458555B (zh) * 2009-06-02 2015-12-16 概念医疗股份有限公司 用含治疗剂的包埋纳米颗粒包衣的非植入医疗设备

Also Published As

Publication number Publication date
WO2011086574A2 (en) 2011-07-21
PT2525782T (pt) 2019-06-06
ES2726952T3 (es) 2019-10-10
EP2525782B1 (en) 2019-03-13
PL2525782T3 (pl) 2019-09-30
US20120321670A1 (en) 2012-12-20
EP2525782A2 (en) 2012-11-28
CA2786671A1 (en) 2011-07-21
DK2525782T3 (da) 2019-06-11
WO2011086574A3 (en) 2011-11-10
EP2525782A4 (en) 2014-05-28

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