TR201906738T4 - Bir çekirdek ve bir kılıf içeren kontrasepsiyonda kullanıma yönelik ilaç taşıyıcı sistem. - Google Patents

Bir çekirdek ve bir kılıf içeren kontrasepsiyonda kullanıma yönelik ilaç taşıyıcı sistem. Download PDF

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Publication number
TR201906738T4
TR201906738T4 TR2019/06738T TR201906738T TR201906738T4 TR 201906738 T4 TR201906738 T4 TR 201906738T4 TR 2019/06738 T TR2019/06738 T TR 2019/06738T TR 201906738 T TR201906738 T TR 201906738T TR 201906738 T4 TR201906738 T4 TR 201906738T4
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TR
Turkey
Prior art keywords
sheath
core
delivery system
drug delivery
contraception
Prior art date
Application number
TR2019/06738T
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English (en)
Inventor
Loxley Andrew
Mitchnick Mark
Hernández Herrero Gonzalo
Ronchi Celestino
Original Assignee
Chemo Res S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Res S L filed Critical Chemo Res S L
Publication of TR201906738T4 publication Critical patent/TR201906738T4/tr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/14Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
    • A61F6/142Wirelike structures, e.g. loops, rings, spirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Buluş; (a) poliüretan içeren bir çekirdek; (b) etilen vinil asetat içeren bir kılıf, söz konusu kılıf, söz konusu çekirdeği büyük ölçüde veya tamamen çevrelemektedir; ve (c) söz konusu çekirdekte ve/veya söz konusu kılıfta çözünmüş veya dağılmış bir veya daha fazla etken farmasötik içerik maddesi içeren bir cihaz; ve bunun preparasyonuna yönelik bir proses ile ilgilidir.
TR2019/06738T 2012-02-14 2013-02-13 Bir çekirdek ve bir kılıf içeren kontrasepsiyonda kullanıma yönelik ilaç taşıyıcı sistem. TR201906738T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261598642P 2012-02-14 2012-02-14

Publications (1)

Publication Number Publication Date
TR201906738T4 true TR201906738T4 (tr) 2019-05-21

Family

ID=47749791

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/06738T TR201906738T4 (tr) 2012-02-14 2013-02-13 Bir çekirdek ve bir kılıf içeren kontrasepsiyonda kullanıma yönelik ilaç taşıyıcı sistem.

Country Status (17)

Country Link
US (2) US9132081B2 (tr)
EP (3) EP2814458B1 (tr)
AR (1) AR089990A1 (tr)
CY (1) CY1121563T1 (tr)
DK (1) DK2814458T3 (tr)
ES (1) ES2730208T3 (tr)
HR (1) HRP20190716T1 (tr)
HU (1) HUE043105T2 (tr)
LT (1) LT2814458T (tr)
PL (1) PL2814458T3 (tr)
PT (1) PT2814458T (tr)
RS (1) RS58690B1 (tr)
SI (1) SI2814458T1 (tr)
TR (1) TR201906738T4 (tr)
TW (1) TW201332585A (tr)
UY (1) UY34625A (tr)
WO (1) WO2013120888A2 (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3052084A1 (en) * 2013-09-30 2016-08-10 Universiteit Gent Polyurethanes as oral drug delivery platform
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
EP3435977A4 (en) 2016-04-01 2019-10-16 Therapeuticsmd, Inc. PHARMACEUTICAL COMPOSITION OF STEROID HORMONE
JP7407595B2 (ja) * 2016-10-05 2024-01-04 タイタン ファーマシューティカルズ インコーポレイテッド バースト放出を低減する薬剤送達用の埋込可能な装置
EP3395335A1 (en) * 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginal ring for the simultaneous release of two active ingredients
CN109248139A (zh) * 2017-07-14 2019-01-22 国家卫生计生委科学技术研究所 复方左炔诺孕酮阴道环的制备方法和应用
WO2019226516A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
CN111989068A (zh) 2018-05-24 2020-11-24 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
CA3230804A1 (en) * 2021-09-22 2023-03-30 Vijay GYANANI Refillable implantable device for delivering a drug compound
EP4215180A1 (en) 2022-01-21 2023-07-26 Sever Pharma Solutions A drug delivery system
EP4215181A1 (en) 2022-01-21 2023-07-26 Sever Pharma Solutions An intravaginal ring

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
ES2327247T3 (es) * 2004-03-24 2009-10-27 N.V. Organon Sistema de administracion de farmacos basado en copolimeros de polietileno y acetato de vinilo.
KR20090083922A (ko) * 2006-11-20 2009-08-04 엔.브이.오가논 나선형 약물 전달 시스템
KR20090110355A (ko) * 2007-01-19 2009-10-21 더 유니버시티 오브 유타 리서치 파운데이션 치료제 전달용 생분해성 질내 기구
WO2008100876A1 (en) 2007-02-12 2008-08-21 Particle Sciences, Inc. Delivery devices containing encapsulated and/or particle-bound active pharmaceutical ingredients
WO2009094573A2 (en) 2008-01-25 2009-07-30 The University Of Utah Research Foundation Linear order release polymer
US20100040671A1 (en) 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
CA2792179C (en) 2010-03-16 2019-04-02 Titan Pharmaceuticals, Inc. Heterogeneous implantable devices for drug delivery

Also Published As

Publication number Publication date
DK2814458T3 (da) 2019-05-13
LT2814458T (lt) 2019-05-27
UY34625A (es) 2013-09-02
US20130209539A1 (en) 2013-08-15
EP2814458A2 (en) 2014-12-24
US20160000706A1 (en) 2016-01-07
AR089990A1 (es) 2014-10-01
EP4212146A3 (en) 2023-09-27
SI2814458T1 (sl) 2019-06-28
CY1121563T1 (el) 2020-05-29
RS58690B1 (sr) 2019-06-28
PL2814458T3 (pl) 2019-08-30
ES2730208T3 (es) 2019-11-08
HRP20190716T1 (hr) 2019-06-14
EP4212146A2 (en) 2023-07-19
US9872829B2 (en) 2018-01-23
TW201332585A (zh) 2013-08-16
EP3449909A3 (en) 2019-05-29
EP3449909A2 (en) 2019-03-06
EP2814458B1 (en) 2019-04-10
US9132081B2 (en) 2015-09-15
WO2013120888A2 (en) 2013-08-22
PT2814458T (pt) 2019-05-30
WO2013120888A3 (en) 2013-10-31
HUE043105T2 (hu) 2019-08-28

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