DK2814458T3 - Lægemiddelleveringssystem til anvendelse i prævention omfattende en kerne og en kappe - Google Patents

Lægemiddelleveringssystem til anvendelse i prævention omfattende en kerne og en kappe Download PDF

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Publication number
DK2814458T3
DK2814458T3 DK13705955.6T DK13705955T DK2814458T3 DK 2814458 T3 DK2814458 T3 DK 2814458T3 DK 13705955 T DK13705955 T DK 13705955T DK 2814458 T3 DK2814458 T3 DK 2814458T3
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DK
Denmark
Prior art keywords
contraception
sheath
core
delivery system
drug delivery
Prior art date
Application number
DK13705955.6T
Other languages
English (en)
Inventor
Andrew Loxley
Mark Mitchnick
Celestino Ronchi
Herrero Gonzalo Hernández
Original Assignee
Chemo Res S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Res S L filed Critical Chemo Res S L
Application granted granted Critical
Publication of DK2814458T3 publication Critical patent/DK2814458T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/14Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
    • A61F6/142Wirelike structures, e.g. loops, rings, spirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK13705955.6T 2012-02-14 2013-02-13 Lægemiddelleveringssystem til anvendelse i prævention omfattende en kerne og en kappe DK2814458T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261598642P 2012-02-14 2012-02-14
PCT/EP2013/052855 WO2013120888A2 (en) 2012-02-14 2013-02-13 Core sheath drug delivery devices

Publications (1)

Publication Number Publication Date
DK2814458T3 true DK2814458T3 (da) 2019-05-13

Family

ID=47749791

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13705955.6T DK2814458T3 (da) 2012-02-14 2013-02-13 Lægemiddelleveringssystem til anvendelse i prævention omfattende en kerne og en kappe

Country Status (17)

Country Link
US (2) US9132081B2 (da)
EP (3) EP3449909A3 (da)
AR (1) AR089990A1 (da)
CY (1) CY1121563T1 (da)
DK (1) DK2814458T3 (da)
ES (1) ES2730208T3 (da)
HR (1) HRP20190716T1 (da)
HU (1) HUE043105T2 (da)
LT (1) LT2814458T (da)
PL (1) PL2814458T3 (da)
PT (1) PT2814458T (da)
RS (1) RS58690B1 (da)
SI (1) SI2814458T1 (da)
TR (1) TR201906738T4 (da)
TW (1) TW201332585A (da)
UY (1) UY34625A (da)
WO (1) WO2013120888A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3052084A1 (en) * 2013-09-30 2016-08-10 Universiteit Gent Polyurethanes as oral drug delivery platform
EP3079659B1 (en) 2013-12-11 2020-10-28 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
CA3020153A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
US20210007973A1 (en) * 2016-10-05 2021-01-14 Titan Pharmaceuticals, Inc. Implantable devices for drug delivery with reduced burst release
EP3395335A1 (en) * 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginal ring for the simultaneous release of two active ingredients
CN109248139A (zh) * 2017-07-14 2019-01-22 国家卫生计生委科学技术研究所 复方左炔诺孕酮阴道环的制备方法和应用
SG11202005947RA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound
AU2019275409A1 (en) 2018-05-24 2020-07-16 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
EP4215181A1 (en) 2022-01-21 2023-07-26 Sever Pharma Solutions An intravaginal ring
EP4215180A1 (en) 2022-01-21 2023-07-26 Sever Pharma Solutions A drug delivery system

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
MXPA06010905A (es) 2004-03-24 2007-03-08 Organon Nv Sistema para el suministro de farmacos basados en copolimeros de polietileno y acetato de vinilo.
EP2097063B1 (en) * 2006-11-20 2013-08-07 Intervet International B.V. Helically-shaped drug delivery system
US20100316691A2 (en) * 2007-01-19 2010-12-16 University Of Utah Research Foundation Biodegradable intravaginal medical device for delivery of therapeutics
EP3391874A3 (en) 2007-02-12 2019-04-24 Particle Sciences, Inc. Delivery devices containing encapsulated and/or particle- bound active pharmaceutical ingredients
US20110045076A1 (en) 2008-01-25 2011-02-24 Kiser Patrick F Linear order release polymer
US20100040671A1 (en) 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
AU2011227289B2 (en) 2010-03-16 2016-01-21 Titan Pharmaceuticals, Inc. Heterogeneous implantable devices for drug delivery

Also Published As

Publication number Publication date
US9132081B2 (en) 2015-09-15
US9872829B2 (en) 2018-01-23
TW201332585A (zh) 2013-08-16
CY1121563T1 (el) 2020-05-29
UY34625A (es) 2013-09-02
AR089990A1 (es) 2014-10-01
RS58690B1 (sr) 2019-06-28
WO2013120888A3 (en) 2013-10-31
EP4212146A2 (en) 2023-07-19
SI2814458T1 (sl) 2019-06-28
HRP20190716T1 (hr) 2019-06-14
EP2814458B1 (en) 2019-04-10
PL2814458T3 (pl) 2019-08-30
US20130209539A1 (en) 2013-08-15
LT2814458T (lt) 2019-05-27
ES2730208T3 (es) 2019-11-08
PT2814458T (pt) 2019-05-30
US20160000706A1 (en) 2016-01-07
EP3449909A2 (en) 2019-03-06
EP4212146A3 (en) 2023-09-27
EP3449909A3 (en) 2019-05-29
TR201906738T4 (tr) 2019-05-21
EP2814458A2 (en) 2014-12-24
WO2013120888A2 (en) 2013-08-22
HUE043105T2 (hu) 2019-08-28

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