TR201900778T4 - İmmünojenik bileşim. - Google Patents
İmmünojenik bileşim. Download PDFInfo
- Publication number
- TR201900778T4 TR201900778T4 TR2019/00778T TR201900778T TR201900778T4 TR 201900778 T4 TR201900778 T4 TR 201900778T4 TR 2019/00778 T TR2019/00778 T TR 2019/00778T TR 201900778 T TR201900778 T TR 201900778T TR 201900778 T4 TR201900778 T4 TR 201900778T4
- Authority
- TR
- Turkey
- Prior art keywords
- protein
- saccharide
- saccharides
- meningitidis
- polysaccharides
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 4
- 150000004676 glycans Chemical class 0.000 abstract 4
- 229920001282 polysaccharide Polymers 0.000 abstract 4
- 239000005017 polysaccharide Substances 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 102000014914 Carrier Proteins Human genes 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 241000588650 Neisseria meningitidis Species 0.000 abstract 2
- 230000021615 conjugation Effects 0.000 abstract 2
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN281MU2012 | 2012-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201900778T4 true TR201900778T4 (tr) | 2019-02-21 |
Family
ID=54259032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2019/00778T TR201900778T4 (tr) | 2012-01-30 | 2013-01-29 | İmmünojenik bileşim. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9198977B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2809349B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6042455B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101897317B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104302315B (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014018815B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2863178C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2809349T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2707294T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE040914T4 (cg-RX-API-DMAC7.html) |
| MX (1) | MX354103B (cg-RX-API-DMAC7.html) |
| PT (1) | PT2809349T (cg-RX-API-DMAC7.html) |
| RU (1) | RU2634405C2 (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201404447WA (cg-RX-API-DMAC7.html) |
| SI (1) | SI2809349T1 (cg-RX-API-DMAC7.html) |
| TR (1) | TR201900778T4 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013114268A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2283857T3 (da) | 2005-06-27 | 2019-10-28 | Glaxosmithkline Biologicals Sa | Vaccinesammensætning omfattende konjugerede native N. Meningitidis kapselpolysaccharider |
| MX364644B (es) * | 2012-11-21 | 2019-05-03 | Serum Inst India Ltd | Produccion de altos rendimientos de polisacaridos bacteriales. |
| WO2015029056A1 (en) * | 2013-08-24 | 2015-03-05 | Bharat Biotech International Limited | A bacterial vaccine and methods for manufacture thereof |
| EP2921856B1 (en) | 2014-03-18 | 2016-09-14 | Serum Institute Of India Private Limited | A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines |
| EP3302542A4 (en) * | 2015-06-08 | 2019-04-10 | Serum Institute Of India Private Limited | METHOD FOR IMPROVING ADSORPTION OF POLYSACCHARIDE PROTEIN CONJUGATES AND POLYVALENT VACCINE FORMULATION THEREOF |
| WO2017006349A1 (en) * | 2015-07-04 | 2017-01-12 | Bharat Biotech International Limited | Polysaccharide vaccine formulations and processes for industrial production of bacterial polysaccharides |
| BR112018068523A2 (pt) * | 2016-03-15 | 2019-01-22 | Msd Wellcome Trust Hilleman Laboratories Pvt Ltd | novos conjugados de polissacarídeo-proteína e processo para obter os mesmos |
| CN106110316A (zh) * | 2016-06-27 | 2016-11-16 | 北京智飞绿竹生物制药有限公司 | 一种肺炎球菌结合物组合疫苗的制备方法 |
| WO2018045286A1 (en) * | 2016-09-02 | 2018-03-08 | Sanofi Pasteur, Inc. | Neisseria meningitidis vaccine |
| CN106397537B (zh) * | 2016-10-13 | 2020-01-07 | 李红臣 | 一种高效快速的多糖蛋白结合疫苗纯化分析方法 |
| GEP20227408B (en) | 2017-05-05 | 2022-08-25 | Serum Institute Of India Pvt Ltd | Method for removal of impurities from bacterial capsular polysaccharide based preparations |
| RU2019142846A (ru) * | 2017-06-27 | 2021-07-27 | Мсд Веллком Траст Хиллеман Лабораторис Пвт. Лтд. | Новая многовалентная вакцинная композиция на основе полисахаридно-белковых конъюгатов и ее состав |
| US20200353064A1 (en) * | 2018-01-29 | 2020-11-12 | Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd. | Novel meningococcal vaccine composition and process thereof |
| WO2019198096A1 (en) * | 2018-04-11 | 2019-10-17 | Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd. | Tetravalent meningococcal vaccine composition and process to prepare thereof |
| JOP20200214A1 (ar) | 2019-09-03 | 2021-03-03 | Serum Institute Of India Pvt Ltd | تركيبات مولدة للمناعة ضد الأمراض المعوية وطرق لتحضيرها |
| MX2022003682A (es) | 2019-09-27 | 2022-04-25 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
| WO2022035816A1 (en) | 2020-08-10 | 2022-02-17 | Inventprise, Llc | Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f |
| CN118078981A (zh) * | 2024-04-26 | 2024-05-28 | 成都康华生物制品股份有限公司 | 一种基于双蛋白载体的五价脑膜炎球菌多糖结合疫苗的制备方法及其产品 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2763244B1 (fr) * | 1997-05-14 | 2003-08-01 | Pasteur Merieux Serums Vacc | Composition vaccinale multivalente a porteur mixte |
| WO2002000249A2 (en) * | 2000-06-29 | 2002-01-03 | Glaxosmithkline Biologicals S.A. | Multivalent vaccine composition |
| GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0130215D0 (en) * | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
| CN103405761A (zh) * | 2003-10-02 | 2013-11-27 | 诺华疫苗和诊断有限公司 | 多种脑膜炎球菌血清群的液体疫苗 |
| DK2283857T3 (da) * | 2005-06-27 | 2019-10-28 | Glaxosmithkline Biologicals Sa | Vaccinesammensætning omfattende konjugerede native N. Meningitidis kapselpolysaccharider |
| GB0513069D0 (en) * | 2005-06-27 | 2005-08-03 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| CA2621023C (en) * | 2005-09-01 | 2019-07-02 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | Multiple vaccination including serogroup c meningococcus |
| ES2707499T3 (es) * | 2005-12-22 | 2019-04-03 | Glaxosmithkline Biologicals Sa | Vacuna de conjugado de polisacárido neumocócico |
| GB0703369D0 (en) * | 2007-02-21 | 2007-03-28 | Health Prot Agency | Compositions Comprising Capsular Polysaccharides and Their Use as Vaccines |
| DK2513056T3 (da) * | 2009-12-17 | 2022-05-23 | Serum Inst Of India Pvt Ltd | Kemiske reagenser til aktivering af polysaccharider i fremstillingen af konjugatvacciner |
| BR112014029313A2 (pt) * | 2012-05-22 | 2017-06-27 | Novartis Ag | conjugado de meningococos do sorogrupo x |
-
2013
- 2013-01-29 WO PCT/IB2013/050739 patent/WO2013114268A1/en not_active Ceased
- 2013-01-29 HU HUE13743463A patent/HUE040914T4/hu unknown
- 2013-01-29 US US14/375,385 patent/US9198977B2/en active Active
- 2013-01-29 DK DK13743463.5T patent/DK2809349T3/da active
- 2013-01-29 TR TR2019/00778T patent/TR201900778T4/tr unknown
- 2013-01-29 JP JP2014555364A patent/JP6042455B2/ja active Active
- 2013-01-29 BR BR112014018815-7A patent/BR112014018815B1/pt active IP Right Grant
- 2013-01-29 SI SI201331329T patent/SI2809349T1/sl unknown
- 2013-01-29 CA CA2863178A patent/CA2863178C/en active Active
- 2013-01-29 RU RU2014134288A patent/RU2634405C2/ru active
- 2013-01-29 SG SG11201404447WA patent/SG11201404447WA/en unknown
- 2013-01-29 EP EP13743463.5A patent/EP2809349B1/en active Active
- 2013-01-29 PT PT13743463T patent/PT2809349T/pt unknown
- 2013-01-29 KR KR1020147024348A patent/KR101897317B1/ko active Active
- 2013-01-29 MX MX2014009250A patent/MX354103B/es active IP Right Grant
- 2013-01-29 CN CN201380017781.9A patent/CN104302315B/zh active Active
- 2013-01-29 ES ES13743463T patent/ES2707294T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HUE040914T4 (hu) | 2019-05-28 |
| US20140377302A1 (en) | 2014-12-25 |
| EP2809349B1 (en) | 2018-12-19 |
| JP2015509111A (ja) | 2015-03-26 |
| CA2863178A1 (en) | 2013-08-08 |
| BR112014018815A8 (pt) | 2017-07-11 |
| US9198977B2 (en) | 2015-12-01 |
| CN104302315A (zh) | 2015-01-21 |
| WO2013114268A1 (en) | 2013-08-08 |
| KR20140123553A (ko) | 2014-10-22 |
| SI2809349T1 (sl) | 2019-03-29 |
| RU2634405C2 (ru) | 2017-10-26 |
| KR101897317B1 (ko) | 2018-09-11 |
| MX2014009250A (es) | 2015-03-19 |
| CA2863178C (en) | 2021-04-06 |
| JP6042455B2 (ja) | 2016-12-14 |
| BR112014018815B1 (pt) | 2022-07-12 |
| DK2809349T3 (da) | 2019-02-18 |
| ES2707294T3 (es) | 2019-04-03 |
| BR112014018815A2 (cg-RX-API-DMAC7.html) | 2017-06-20 |
| SG11201404447WA (en) | 2014-08-28 |
| EP2809349A1 (en) | 2014-12-10 |
| CN104302315B (zh) | 2018-02-06 |
| RU2014134288A (ru) | 2016-03-20 |
| PT2809349T (pt) | 2019-02-01 |
| MX354103B (es) | 2018-02-13 |
| EP2809349A4 (en) | 2015-08-26 |
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