TR200401489T4 - Doğrudan tabletleme formülasyonların ve yardımcılarının hazırlanması - Google Patents

Doğrudan tabletleme formülasyonların ve yardımcılarının hazırlanması

Info

Publication number
TR200401489T4
TR200401489T4 TR2004/01489T TR200401489T TR200401489T4 TR 200401489 T4 TR200401489 T4 TR 200401489T4 TR 2004/01489 T TR2004/01489 T TR 2004/01489T TR 200401489 T TR200401489 T TR 200401489T TR 200401489 T4 TR200401489 T4 TR 200401489T4
Authority
TR
Turkey
Prior art keywords
weight
direct tabletting
adjuvants
preparation
excipient
Prior art date
Application number
TR2004/01489T
Other languages
English (en)
Inventor
Yeh Ta-Shuong
Hungting Yeh Daniel
Original Assignee
Wei Ming Pharmaceutical Mfg. Co. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wei Ming Pharmaceutical Mfg. Co. Ltd. filed Critical Wei Ming Pharmaceutical Mfg. Co. Ltd.
Publication of TR200401489T4 publication Critical patent/TR200401489T4/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Dogrudan tabletleme formülasyonlarinin veya yardimcilarinin hazirlanmasi için termal yapisma granülasyon yöntemi açiklanmistir. Islem, A)Yaklasik %5 ila yaklasik %99 agirlik oraninda bir vey birden fazla sulandirici içerik madde ve/veya 0 ila yaklasik %99 agirlik oraninda farmasötik etkin bilesen; B) Yaklasik %1 ila yaklasik %95 agirlik oraninda baglayici içerik madde ve istege bagli olarak, C) Yaklasik 0 ila yaklasik %10 agirlik oraninda bir dagitici içerik maddelerinde olusan karisimin tamaminin veya bir kisminin, düsük nem orani veya farmasötik açidan kabul edilebilir bir çözücünün düsük orani kosulu altinda kapali sistemde tambur rotasyonu altinda granül olusmuna kadar yaklasik 30 ila 130 C sicakliga tabi tutulmasi isleminden ibarettir.
TR2004/01489T 2001-05-01 2001-09-04 Doğrudan tabletleme formülasyonların ve yardımcılarının hazırlanması TR200401489T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/847,017 US6761905B2 (en) 2001-05-01 2001-05-01 Process for the preparation of direct tabletting formulations and aids

Publications (1)

Publication Number Publication Date
TR200401489T4 true TR200401489T4 (tr) 2004-07-21

Family

ID=25299560

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/01489T TR200401489T4 (tr) 2001-05-01 2001-09-04 Doğrudan tabletleme formülasyonların ve yardımcılarının hazırlanması

Country Status (11)

Country Link
US (1) US6761905B2 (tr)
EP (1) EP1256338B1 (tr)
CN (1) CN1309375C (tr)
AT (1) ATE266388T1 (tr)
DE (1) DE60103247T2 (tr)
DK (1) DK1256338T3 (tr)
ES (1) ES2220640T3 (tr)
HK (1) HK1050147A1 (tr)
PT (1) PT1256338E (tr)
TR (1) TR200401489T4 (tr)
TW (1) TWI284541B (tr)

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Publication number Priority date Publication date Assignee Title
US20040221631A1 (en) * 2002-09-05 2004-11-11 Kerrigan Kurt J. Composition for fertilizer tablet
RU2008104638A (ru) * 2005-07-07 2009-08-20 Фарнэм Компаниз, Инк. (Us) Фармацевтические композиции хорошо растворимых в воде лекарственных средств, обеспечивающих их замедленное высвобождение
US8951562B2 (en) 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
JP5612462B2 (ja) 2007-04-13 2014-10-22 ダウ グローバル テクノロジーズ エルエルシー 剤形用の粒状物質
US20100055180A1 (en) * 2007-10-10 2010-03-04 Mallinckrodt Baker, Inc. Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof
MX339320B (es) * 2007-10-10 2016-05-20 Avantor Performance Mat Inc Excipiente basado en celulosa microcristalina granular con alta funcionalidad y directamente comprimible, procedimiento de elaboracion y uso del mismo.
SG171362A1 (en) * 2008-11-20 2011-07-28 Avantor Performance Mat Inc Directly compressible high functionality granular dibasic calcium phosphate based co-processed excipient
DK2413912T3 (da) * 2009-04-01 2019-06-17 Bial Portela & Ca Sa Farmaceutiske formuleringer, der omfatter nitrocatecholderivater, og metoder til fremstilling deraf
WO2010151893A1 (en) 2009-06-26 2010-12-29 Taris Biomedical, Inc. Implantable drug delivery devices and methods of making the same
ES2758129T3 (es) 2009-11-11 2020-05-04 Borealis Ag Un cable y procedimiento de producción del mismo
WO2011115067A1 (ja) * 2010-03-19 2011-09-22 第一三共株式会社 抗凝固剤の溶出改善方法
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
CN111374953A (zh) * 2018-12-31 2020-07-07 上海鼎雅药物化学科技有限公司 对乙酰氨基酚片及其制备工艺
GB2595203A (en) 2020-03-03 2021-11-24 Alkaloid Ad Skopje Formulation
CN112076166A (zh) * 2020-09-21 2020-12-15 湖州展望药业有限公司 一种直压淀粉及其生产方法
CN114522147B (zh) * 2020-11-23 2023-08-04 武汉武药科技有限公司 卡谷氨酸固体制剂及其制备方法

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Publication number Priority date Publication date Assignee Title
US4072535A (en) * 1970-12-28 1978-02-07 A. E. Staley Manufacturing Company Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules
DE3447422A1 (de) * 1984-12-24 1986-06-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von ascorbinsaeure-granulat
DE3505433A1 (de) 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
DE3506276C1 (de) 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
US4757090A (en) * 1986-07-14 1988-07-12 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
EP0273209B1 (en) 1986-12-30 1992-01-15 American Cyanamid Company Composition of matter containing polycarbophil
US5200193A (en) 1987-04-22 1993-04-06 Mcneilab, Inc. Pharmaceutical sustained release matrix and process
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EP0487774B1 (en) * 1990-11-29 1994-10-26 Wei Ming Pharmaceutical Mfg. Co. Ltd. A direct tabletting auxiliary
AU3136293A (en) 1991-11-15 1993-06-15 Isp Investments Inc. Pharmaceutical tablet with pvp having an enhanced drug dissolution rate
DE4418837A1 (de) * 1994-05-30 1995-12-07 Bayer Ag Thermisches Granulierverfahren
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Also Published As

Publication number Publication date
DK1256338T3 (da) 2004-09-06
CN1309375C (zh) 2007-04-11
DE60103247T2 (de) 2005-05-04
EP1256338A3 (en) 2003-01-29
US20030017198A1 (en) 2003-01-23
CN1383813A (zh) 2002-12-11
EP1256338B1 (en) 2004-05-12
ATE266388T1 (de) 2004-05-15
DE60103247D1 (de) 2004-06-17
ES2220640T3 (es) 2004-12-16
HK1050147A1 (en) 2003-06-13
PT1256338E (pt) 2004-09-30
US6761905B2 (en) 2004-07-13
EP1256338A2 (en) 2002-11-13
TWI284541B (en) 2007-08-01

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