TR200202544T2 - Torasemid'in yeni polimorfu V - Google Patents
Torasemid'in yeni polimorfu VInfo
- Publication number
- TR200202544T2 TR200202544T2 TR2002/02544T TR200202544T TR200202544T2 TR 200202544 T2 TR200202544 T2 TR 200202544T2 TR 2002/02544 T TR2002/02544 T TR 2002/02544T TR 200202544 T TR200202544 T TR 200202544T TR 200202544 T2 TR200202544 T2 TR 200202544T2
- Authority
- TR
- Turkey
- Prior art keywords
- torasemide
- new polymorph
- torasemid
- preparation
- modifications
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Bulus torasemid'in yeni bir polimorf (çok sekilli) V'i ile, bunun hazirlanmasi için olan bir islem ile, torasemid'in kristal haldeki I ve III modifikasyonlarinin hazirlanmasi için ham madde olarak bunun kullanilmasi ile, amorf (sekilsiz) torasemid modifikasyonlari ile ve torasemid'in farmasötik olarak kabul edilebilir tuzlari ile, aktif madde olarak torasemid'in söz konusu yeni polimorf V'ini içeren farmasötik biçimleri ile, hem de bunun kullanimi ile ilgilidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HR20000328A HRP20000328A2 (en) | 2000-05-19 | 2000-05-19 | Novel polymorph v of torasemide |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200202544T2 true TR200202544T2 (tr) | 2003-03-21 |
Family
ID=10947111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/02544T TR200202544T2 (tr) | 2000-05-19 | 2000-09-25 | Torasemid'in yeni polimorfu V |
Country Status (32)
Country | Link |
---|---|
US (2) | US7241782B1 (tr) |
EP (1) | EP1283828B1 (tr) |
JP (1) | JP2003533512A (tr) |
KR (1) | KR20030016267A (tr) |
CN (1) | CN1520403A (tr) |
AP (1) | AP2002002679A0 (tr) |
AR (1) | AR028840A1 (tr) |
AT (1) | ATE342890T1 (tr) |
AU (1) | AU2000274381A1 (tr) |
BG (1) | BG107407A (tr) |
BR (1) | BR0015877A (tr) |
CA (1) | CA2409699A1 (tr) |
CZ (1) | CZ20024104A3 (tr) |
DE (1) | DE60031450T2 (tr) |
DZ (1) | DZ3356A1 (tr) |
EA (1) | EA005003B1 (tr) |
EE (1) | EE200200637A (tr) |
GE (1) | GEP20043321B (tr) |
HR (1) | HRP20000328A2 (tr) |
HU (1) | HUP0302135A2 (tr) |
IL (1) | IL152810A0 (tr) |
IS (1) | IS6620A (tr) |
MA (1) | MA25748A1 (tr) |
MX (1) | MXPA02011402A (tr) |
NO (1) | NO20025509L (tr) |
NZ (1) | NZ522544A (tr) |
PL (1) | PL358257A1 (tr) |
SK (1) | SK17712002A3 (tr) |
TR (1) | TR200202544T2 (tr) |
WO (1) | WO2001087841A1 (tr) |
YU (1) | YU84202A (tr) |
ZA (1) | ZA200209181B (tr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU781461C (en) * | 1999-08-11 | 2006-02-23 | Teva Pharmaceutical Industries Ltd. | Torsemide polymorphs |
IN192178B (tr) | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
US7067385B2 (en) * | 2003-09-04 | 2006-06-27 | Micron Technology, Inc. | Support for vertically oriented capacitors during the formation of a semiconductor device |
CN1824647B (zh) * | 2005-02-22 | 2011-04-20 | 田边三菱制药株式会社 | (±)2-(二甲基氨基)-1-{[O-(m-甲氧基苯乙基)苯氧基]甲基}乙基氢琥珀酸酯盐酸盐的晶体 |
CN100421662C (zh) * | 2005-11-08 | 2008-10-01 | 周卓和 | 托拉塞米分散片及其制备方法和应用 |
CN104370805B (zh) * | 2013-08-13 | 2016-09-07 | 天津汉瑞药业有限公司 | 托拉塞米化合物 |
CN105949115A (zh) * | 2016-05-26 | 2016-09-21 | 南京正科医药股份有限公司 | 一种新晶型托拉塞米 |
CN115417810B (zh) * | 2022-09-22 | 2023-10-10 | 南京正科医药股份有限公司 | 一种托拉塞米晶型ⅰ的精制方法 |
CN117486789A (zh) * | 2023-12-29 | 2024-02-02 | 江西中医药大学 | 一种托拉塞米共晶盐及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4055650A (en) | 1974-04-17 | 1977-10-25 | A. Christiaens Societe Anonyme | Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines |
GB1477664A (en) | 1974-04-17 | 1977-06-22 | Christiaens Sa A | Pyridine derivatives |
US4476248A (en) * | 1983-02-28 | 1984-10-09 | The Upjohn Company | Crystallization of ibuprofen |
IN182496B (tr) * | 1996-02-20 | 1999-04-17 | Reddy Research Foundation | |
HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
US5914336A (en) * | 1998-06-02 | 1999-06-22 | Boehringer Mannheim Gmbh | Method of controlling the serum solubility of orally administered torasemide and composition relating thereto |
-
2000
- 2000-05-19 HR HR20000328A patent/HRP20000328A2/hr not_active Application Discontinuation
- 2000-06-26 AR ARP000103199A patent/AR028840A1/es unknown
- 2000-09-25 EA EA200201236A patent/EA005003B1/ru not_active IP Right Cessation
- 2000-09-25 TR TR2002/02544T patent/TR200202544T2/tr unknown
- 2000-09-25 KR KR1020027015607A patent/KR20030016267A/ko not_active Application Discontinuation
- 2000-09-25 NZ NZ522544A patent/NZ522544A/en unknown
- 2000-09-25 CZ CZ20024104A patent/CZ20024104A3/cs unknown
- 2000-09-25 BR BR0015877-1A patent/BR0015877A/pt not_active IP Right Cessation
- 2000-09-25 WO PCT/HR2000/000033 patent/WO2001087841A1/en active IP Right Grant
- 2000-09-25 SK SK1771-2002A patent/SK17712002A3/sk unknown
- 2000-09-25 DE DE60031450T patent/DE60031450T2/de not_active Expired - Fee Related
- 2000-09-25 GE GE4998A patent/GEP20043321B/en unknown
- 2000-09-25 DZ DZ003356A patent/DZ3356A1/fr active
- 2000-09-25 IL IL15281000A patent/IL152810A0/xx unknown
- 2000-09-25 JP JP2001584237A patent/JP2003533512A/ja active Pending
- 2000-09-25 PL PL00358257A patent/PL358257A1/xx not_active Application Discontinuation
- 2000-09-25 AU AU2000274381A patent/AU2000274381A1/en not_active Abandoned
- 2000-09-25 HU HU0302135A patent/HUP0302135A2/hu unknown
- 2000-09-25 EP EP00962739A patent/EP1283828B1/en not_active Expired - Lifetime
- 2000-09-25 US US10/276,881 patent/US7241782B1/en not_active Expired - Fee Related
- 2000-09-25 AP APAP/P/2002/002679A patent/AP2002002679A0/en unknown
- 2000-09-25 CN CNA008196567A patent/CN1520403A/zh active Pending
- 2000-09-25 CA CA002409699A patent/CA2409699A1/en not_active Abandoned
- 2000-09-25 EE EEP200200637A patent/EE200200637A/xx unknown
- 2000-09-25 MX MXPA02011402A patent/MXPA02011402A/es unknown
- 2000-09-25 YU YU84202A patent/YU84202A/sh unknown
- 2000-09-25 AT AT00962739T patent/ATE342890T1/de not_active IP Right Cessation
-
2002
- 2002-11-11 MA MA26902A patent/MA25748A1/fr unknown
- 2002-11-12 ZA ZA200209181A patent/ZA200209181B/en unknown
- 2002-11-14 IS IS6620A patent/IS6620A/is unknown
- 2002-11-15 NO NO20025509A patent/NO20025509L/no not_active Application Discontinuation
- 2002-12-19 BG BG107407A patent/BG107407A/xx unknown
-
2007
- 2007-06-14 US US11/763,156 patent/US20070238759A1/en not_active Abandoned
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