TR200102070T2 - Diaril 1,3,4-oksadiazolon'un karbamat türevleri. - Google Patents

Diaril 1,3,4-oksadiazolon'un karbamat türevleri.

Info

Publication number
TR200102070T2
TR200102070T2 TR2001/02070T TR200102070T TR200102070T2 TR 200102070 T2 TR200102070 T2 TR 200102070T2 TR 2001/02070 T TR2001/02070 T TR 2001/02070T TR 200102070 T TR200102070 T TR 200102070T TR 200102070 T2 TR200102070 T2 TR 200102070T2
Authority
TR
Turkey
Prior art keywords
oxadiazolone
diaryl
carbamate derivatives
formula
carbamate
Prior art date
Application number
TR2001/02070T
Other languages
English (en)
Inventor
Hewawasam Piyasena
Chen Xi
E. Jr. Starrett John
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of TR200102070T2 publication Critical patent/TR200102070T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Mevcut bulus, R1 ve R2'nin burada anlatildigi gibi oldugu genel formül (I)'e sahip olan ve genis iletimli kalsiyum ile aktive edilen kanallarin açilmasina yanit veren rahatsizliklarin tedavisinde faydali olan yeni karbamat okzadiazolon türevleri veya bunlarin toksik olmayan, farmasötik olarak kabul edilebilir tuz veya solvatini sunmaktadir. (Formül I)
TR2001/02070T 1999-01-29 2000-01-20 Diaril 1,3,4-oksadiazolon'un karbamat türevleri. TR200102070T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11791399P 1999-01-29 1999-01-29

Publications (1)

Publication Number Publication Date
TR200102070T2 true TR200102070T2 (tr) 2001-12-21

Family

ID=22375485

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02070T TR200102070T2 (tr) 1999-01-29 2000-01-20 Diaril 1,3,4-oksadiazolon'un karbamat türevleri.

Country Status (18)

Country Link
US (1) US6162817A (tr)
EP (1) EP1150978A4 (tr)
JP (1) JP2002535402A (tr)
KR (1) KR20010101869A (tr)
CN (1) CN1133636C (tr)
AU (1) AU771471B2 (tr)
BR (1) BR0007255A (tr)
CA (1) CA2358964A1 (tr)
CZ (1) CZ20012712A3 (tr)
HU (1) HUP0200089A3 (tr)
ID (1) ID29269A (tr)
IL (1) IL144540A0 (tr)
NO (1) NO20013715L (tr)
NZ (1) NZ512077A (tr)
PL (1) PL349097A1 (tr)
TR (1) TR200102070T2 (tr)
WO (1) WO2000044745A1 (tr)
ZA (1) ZA200104304B (tr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297241B1 (en) * 1999-01-29 2001-10-02 Bristol-Myers Squibb Company Carbamate derivatives of diaryl 1,3,4-oxadiazolone
US20020045566A1 (en) * 2000-10-13 2002-04-18 Gribkoff Valentin K. Selective maxi-K potassium channel openers functional under conditions of high intracellular calcium concentration, methods and uses thereof
CA2708281A1 (en) 2007-12-11 2009-08-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
CN104710379B (zh) * 2015-03-09 2017-01-18 华南理工大学 一种bms‑191011的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH583213A5 (tr) * 1973-05-21 1976-12-31 Ciba Geigy Ag
IT1251488B (it) * 1991-09-17 1995-05-15 Mini Ricerca Scient Tecnolog Ossa(tia)diazol- e triazol-oni(tioni) ad attivita' acaricida ed insetticida
US5234947A (en) * 1991-11-07 1993-08-10 New York University Potassium channel activating compounds and methods of use thereof
TW467902B (en) * 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators
ATE252590T1 (de) * 1998-01-29 2003-11-15 Bristol Myers Squibb Co Phosphorylierte derivate des diaryl 1,3,4 oxadiazolon
JP2002501912A (ja) * 1998-01-29 2002-01-22 ブリストル−マイヤーズ スクイブ カンパニー ジアリール１、３、４−オキサジアゾロンのベンゾエート誘導体
AU736599B2 (en) * 1998-01-29 2001-08-02 Bristol-Myers Squibb Company Amino acid derivatives of diaryl 1,3,4-oxadiazolone
WO1999038510A1 (en) * 1998-01-29 1999-08-05 Bristol-Myers Squibb Company Derivatives of 1,3,4-oxadiazolone

Also Published As

Publication number Publication date
PL349097A1 (en) 2002-07-01
CN1336926A (zh) 2002-02-20
WO2000044745A1 (en) 2000-08-03
CZ20012712A3 (cs) 2001-10-17
HUP0200089A3 (en) 2004-07-28
JP2002535402A (ja) 2002-10-22
AU771471B2 (en) 2004-03-25
CN1133636C (zh) 2004-01-07
CA2358964A1 (en) 2000-08-03
BR0007255A (pt) 2001-09-25
AU2970000A (en) 2000-08-18
NO20013715L (no) 2001-09-17
EP1150978A1 (en) 2001-11-07
IL144540A0 (en) 2002-05-23
ZA200104304B (en) 2002-01-24
US6162817A (en) 2000-12-19
ID29269A (id) 2001-08-16
NZ512077A (en) 2003-07-25
EP1150978A4 (en) 2002-06-12
NO20013715D0 (no) 2001-07-27
HUP0200089A2 (hu) 2002-05-29
KR20010101869A (ko) 2001-11-15

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