TR200102043T2 - Hücre yapışma önleyicileri olarak monosakkaritlerin 2,3-O-izopropiliden türevleri. - Google Patents

Hücre yapışma önleyicileri olarak monosakkaritlerin 2,3-O-izopropiliden türevleri.

Info

Publication number
TR200102043T2
TR200102043T2 TR2001/02043T TR200102043T TR200102043T2 TR 200102043 T2 TR200102043 T2 TR 200102043T2 TR 2001/02043 T TR2001/02043 T TR 2001/02043T TR 200102043 T TR200102043 T TR 200102043T TR 200102043 T2 TR200102043 T2 TR 200102043T2
Authority
TR
Turkey
Prior art keywords
cell adhesion
monosaccharides
adhesion inhibitors
isopropylidene
prevention
Prior art date
Application number
TR2001/02043T
Other languages
English (en)
Inventor
K. Arora Sudershan
Kishore Nawal
Bahadur Gupta Jang
D. Joshi Vishwas
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of TR200102043T2 publication Critical patent/TR200102043T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Bu bulus,genel olarak formül (I)'e ait 2-3-O-izopropiliden -a-L-ksilo-2-heksulofuranosik asit türevlerinin sentezlenmesi için bilesikler ve islemler ile ilgilidir,bu bulusun bilesikleri ,digerlerinin yaninda, bronsit astim, romatizmali arterit ,I tipi diyabet,çoklu skleroz, allograft reddi ve sedef hastaligi dahil hücre yapismasinin aracilik ettigi patolojilerin ve hücre yapismasinin önlenmesi ve engellenmesi için yararlidir.Bu bulus ayrica,2-3-O-izopropiliden -a-L-ksilo-2-heksulofuranosik asit türevlerini içeren farmakolojik kompozisyonlar ve yukarida belirtilen patolojilerin tedavi edilmesi yöntemleri ile ilgilidir.
TR2001/02043T 1999-01-15 2000-01-10 Hücre yapışma önleyicileri olarak monosakkaritlerin 2,3-O-izopropiliden türevleri. TR200102043T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN86DE1999 IN190975B (tr) 1999-01-15 1999-01-15
US09/276,368 US6590085B1 (en) 1999-01-15 1999-03-25 Derivatives of monosaccharides as cell adhesion inhibitors

Publications (1)

Publication Number Publication Date
TR200102043T2 true TR200102043T2 (tr) 2001-11-21

Family

ID=11088155

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02043T TR200102043T2 (tr) 1999-01-15 2000-01-10 Hücre yapışma önleyicileri olarak monosakkaritlerin 2,3-O-izopropiliden türevleri.

Country Status (31)

Country Link
US (5) US6590085B1 (tr)
EP (1) EP1147119B1 (tr)
JP (1) JP2002534530A (tr)
CN (1) CN1167707C (tr)
AR (1) AR022235A1 (tr)
AT (1) ATE250074T1 (tr)
AU (1) AU768511B2 (tr)
BG (1) BG105745A (tr)
BR (1) BR0007553A (tr)
CA (1) CA2359986A1 (tr)
CO (1) CO5180591A1 (tr)
CR (1) CR6423A (tr)
CZ (1) CZ20012540A3 (tr)
DE (1) DE60005300T2 (tr)
DK (1) DK1147119T3 (tr)
ES (1) ES2206176T3 (tr)
HK (1) HK1041270A1 (tr)
HR (1) HRP20010529B1 (tr)
HU (1) HUP0105116A3 (tr)
ID (1) ID30351A (tr)
IN (1) IN190975B (tr)
MA (1) MA25342A1 (tr)
MX (1) MXPA01007187A (tr)
MY (1) MY121135A (tr)
NZ (2) NZ527483A (tr)
PA (1) PA8489901A1 (tr)
PT (1) PT1147119E (tr)
SK (1) SK284241B6 (tr)
TR (1) TR200102043T2 (tr)
WO (1) WO2000042054A1 (tr)
YU (1) YU50701A (tr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN190975B (tr) * 1999-01-15 2003-09-06 Ranbaxy Lab Ltd
GEP20084406B (en) 2003-05-30 2008-06-25 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as hmg-co inhibitors
WO2006024926A1 (en) * 2004-09-02 2006-03-09 Ranbaxy Laboratories Limited Monosaccharide derivatives
EP1902063A2 (en) * 2004-12-22 2008-03-26 Ranbaxy Laboratories Limited Derivatives of pentose monosaccharides as anti-inflammatory compounds
US20090054519A1 (en) * 2005-07-22 2009-02-26 Abhijit Ray Derivatives of monosaccharides as 5-lipoxygenase inhibitors
AU2006313430B2 (en) * 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
US20080114031A1 (en) * 2006-03-29 2008-05-15 Sattigeri Viswajanani J Monosaccharide derivatives
EP1864992A2 (en) * 2006-05-30 2007-12-12 Ranbaxy Laboratories, Ltd. Monosaccharide derivatives
US20080300196A1 (en) * 2006-10-03 2008-12-04 Ashwani Kumar Verma Monosaccharide derivatives
US10034995B2 (en) * 2007-09-20 2018-07-31 Resmed Limited Retractable tube for CPAP

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2715121A (en) 1950-09-09 1955-08-09 American Home Prod Alkyl sugar derivatives and their preparation
US4056322A (en) 1973-12-14 1977-11-01 Strategic Medical Research Corporation Preparation of ethers of monosaccharides
US4735934A (en) 1981-02-17 1988-04-05 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US4996195A (en) * 1989-01-09 1991-02-26 Greenwich Pharmaceuticals Inc. Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives
US5010058A (en) 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
FR2652540B1 (fr) 1989-10-02 1995-06-02 Imaje Sa Circuit d'encre notamment destine a la mise en pression d'une encre a pigments pour imprimante a jet d'encre.
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
US5258402A (en) 1992-06-11 1993-11-02 Mcneil-Ppc, Inc. Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates
US5432163A (en) 1992-11-13 1995-07-11 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
US5637570A (en) * 1995-05-09 1997-06-10 Chemora Pharmochem Disubstituted and trisubstituted derivatives of 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonic acid having anti-cancer, anti-inflammatory and anti-proliferative activity
IN190975B (tr) * 1999-01-15 2003-09-06 Ranbaxy Lab Ltd

Also Published As

Publication number Publication date
US20040023900A1 (en) 2004-02-05
PA8489901A1 (es) 2000-09-29
EP1147119A1 (en) 2001-10-24
EP1147119B1 (en) 2003-09-17
CR6423A (tr) 2004-03-09
US7005516B2 (en) 2006-02-28
CA2359986A1 (en) 2000-07-20
BG105745A (en) 2002-05-31
JP2002534530A (ja) 2002-10-15
WO2000042054A1 (en) 2000-07-20
US20040018995A1 (en) 2004-01-29
DK1147119T3 (da) 2004-01-19
AU768511B2 (en) 2003-12-18
DE60005300T2 (de) 2004-07-15
ATE250074T1 (de) 2003-10-15
US7005422B2 (en) 2006-02-28
US6590085B1 (en) 2003-07-08
HK1041270A1 (en) 2002-07-05
HUP0105116A2 (hu) 2003-04-28
CN1167707C (zh) 2004-09-22
SK284241B6 (en) 2004-11-03
AR022235A1 (es) 2002-09-04
SK10132001A3 (sk) 2002-01-07
HRP20010529A2 (en) 2002-08-31
CO5180591A1 (es) 2002-07-30
US20040029820A1 (en) 2004-02-12
US20040019191A1 (en) 2004-01-29
IN190975B (tr) 2003-09-06
MXPA01007187A (es) 2002-04-24
MA25342A1 (fr) 2001-12-31
MY121135A (en) 2005-12-30
AU1886100A (en) 2000-08-01
HRP20010529B1 (en) 2005-02-28
BR0007553A (pt) 2001-12-18
CZ20012540A3 (cs) 2002-02-13
NZ512852A (en) 2004-02-27
YU50701A (sh) 2005-06-10
US7037899B2 (en) 2006-05-02
NZ527483A (en) 2005-02-25
PT1147119E (pt) 2004-02-27
HUP0105116A3 (en) 2003-05-28
ES2206176T3 (es) 2004-05-16
ID30351A (id) 2001-11-22
CN1343213A (zh) 2002-04-03
DE60005300D1 (de) 2003-10-23

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