TR200100427T2 - Karbonik asit türevlerinin endotelin-reseptör antagonistleri olarak kullanımları - Google Patents

Karbonik asit türevlerinin endotelin-reseptör antagonistleri olarak kullanımları

Info

Publication number
TR200100427T2
TR200100427T2 TR2001/00427T TR200100427T TR200100427T2 TR 200100427 T2 TR200100427 T2 TR 200100427T2 TR 2001/00427 T TR2001/00427 T TR 2001/00427T TR 200100427 T TR200100427 T TR 200100427T TR 200100427 T2 TR200100427 T2 TR 200100427T2
Authority
TR
Turkey
Prior art keywords
endothelin
acid derivatives
carbonic acid
receptor antagonists
substituents
Prior art date
Application number
TR2001/00427T
Other languages
English (en)
Inventor
Amberg Wilhelm
Jansen Rolf
Kettschau Georg
Hergenr�Der Stefan
Raschack Manferd
Unger Liliane
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of TR200100427T2 publication Critical patent/TR200100427T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Eldeki bulus,içindeki ikame maddeleri, tanimda açiklanan anlamlara sahip olan formül I'in karbonik asit türevlerini ve bunlarin endotelin-reseptör antagonistleri olarak üretilmeleri ve kullanilmalarini konu almaktadir.
TR2001/00427T 1998-08-10 1999-08-07 Karbonik asit türevlerinin endotelin-reseptör antagonistleri olarak kullanımları TR200100427T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19836044A DE19836044A1 (de) 1998-08-10 1998-08-10 Neue Carbonsäurederivate, die Ketoseitenketten tragen, ihre Herstellung und Verwendung als Endothelin-Rezeptorantagonisten

Publications (1)

Publication Number Publication Date
TR200100427T2 true TR200100427T2 (tr) 2001-07-23

Family

ID=7876981

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00427T TR200100427T2 (tr) 1998-08-10 1999-08-07 Karbonik asit türevlerinin endotelin-reseptör antagonistleri olarak kullanımları

Country Status (22)

Country Link
EP (1) EP1104410A1 (tr)
JP (1) JP2002522531A (tr)
KR (1) KR20010072378A (tr)
CN (1) CN1323298A (tr)
AR (1) AR020147A1 (tr)
AU (1) AU5374199A (tr)
BG (1) BG105236A (tr)
BR (1) BR9912889A (tr)
CA (1) CA2340167A1 (tr)
CO (1) CO5261504A1 (tr)
DE (1) DE19836044A1 (tr)
HK (1) HK1042086A1 (tr)
HR (1) HRP20010164A2 (tr)
HU (1) HUP0104007A3 (tr)
ID (1) ID27965A (tr)
IL (1) IL140915A0 (tr)
NO (1) NO20010622D0 (tr)
PL (1) PL345998A1 (tr)
SK (1) SK832001A3 (tr)
TR (1) TR200100427T2 (tr)
WO (1) WO2000009489A1 (tr)
ZA (1) ZA200101975B (tr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19924892A1 (de) * 1999-06-01 2000-12-07 Basf Ag Neue Carbonsäurederivate mit arylsubstituierten Stickstoffheterocyclen, ihre Herstellung und Verwendung als Endothelin Rezeptorantagonisten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19636046A1 (de) * 1996-09-05 1998-03-12 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten

Also Published As

Publication number Publication date
CO5261504A1 (es) 2003-03-31
HRP20010164A2 (en) 2002-04-30
HUP0104007A3 (en) 2002-12-28
BR9912889A (pt) 2001-05-08
HUP0104007A2 (hu) 2002-05-29
DE19836044A1 (de) 2000-02-17
CN1323298A (zh) 2001-11-21
SK832001A3 (en) 2001-11-06
BG105236A (en) 2001-12-29
EP1104410A1 (de) 2001-06-06
NO20010622L (no) 2001-02-06
ID27965A (id) 2001-05-03
IL140915A0 (en) 2002-02-10
AR020147A1 (es) 2002-04-10
ZA200101975B (en) 2002-03-11
KR20010072378A (ko) 2001-07-31
AU5374199A (en) 2000-03-06
PL345998A1 (en) 2002-01-14
HK1042086A1 (zh) 2002-08-02
WO2000009489A1 (de) 2000-02-24
JP2002522531A (ja) 2002-07-23
CA2340167A1 (en) 2000-02-24
NO20010622D0 (no) 2001-02-06

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