TR200002465T2 - Mideye ve/veya on iki parmak bağırsağına yapışan bir eczacılık komposizyonu - Google Patents

Mideye ve/veya on iki parmak bağırsağına yapışan bir eczacılık komposizyonu

Info

Publication number
TR200002465T2
TR200002465T2 TR2000/02465T TR200002465T TR200002465T2 TR 200002465 T2 TR200002465 T2 TR 200002465T2 TR 2000/02465 T TR2000/02465 T TR 2000/02465T TR 200002465 T TR200002465 T TR 200002465T TR 200002465 T2 TR200002465 T2 TR 200002465T2
Authority
TR
Turkey
Prior art keywords
stomach
drug
mucosa
fingers
release
Prior art date
Application number
TR2000/02465T
Other languages
English (en)
Inventor
Inagi Toshio
Shirai Hiroyuki
Yamaguchi Norikazu
Nishino Takeshi
Original Assignee
Kowa C0., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10072099A external-priority patent/JPH11269064A/ja
Application filed by Kowa C0., Ltd. filed Critical Kowa C0., Ltd.
Publication of TR200002465T2 publication Critical patent/TR200002465T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

Mideye ve/veya on iki parmak bagirsagina ait mukozaya yapiskan eczacilik komposizyonu bu bulusa göre pH7a bagimli yapisma özelligini göstermekte böylece asitli kosullar altinda sindirme ait bölgenin mukozasi üzerine dogrudan yapismakta ve ilacin preparasyondan mideye ve/veya on iki parmak bagirsagina ait mukozaya dogrudan serbest birakilmasini saglayan sindirime ait bölgede yüksek alikoyulma süresine sahip olmakta; ve bu kompozisyon ayrica ilacin sürekli serbest birakilmasina ve aktif malzemelerin mideye ve/veya on iki parmak bagirsagina ait mukoza içine etkili geçisine izin veren kontrollü serbest birakilma özelligini göstermektedir. Preparasyonun yüksek güvenlige sahip olabilmesi ve aktif malzemelerin kullanimina izin vermesi için yeterli etkiler daha düsük doz uygulamasi ile elde edilir.
TR2000/02465T 1998-03-20 1999-03-17 Mideye ve/veya on iki parmak bağırsağına yapışan bir eczacılık komposizyonu TR200002465T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7209898 1998-03-20
JP10072099A JPH11269064A (ja) 1998-03-20 1998-03-20 胃・十二指腸付着性医薬組成物

Publications (1)

Publication Number Publication Date
TR200002465T2 true TR200002465T2 (tr) 2000-12-21

Family

ID=26413237

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02465T TR200002465T2 (tr) 1998-03-20 1999-03-17 Mideye ve/veya on iki parmak bağırsağına yapışan bir eczacılık komposizyonu

Country Status (17)

Country Link
US (1) US6582720B1 (tr)
EP (1) EP1062955A1 (tr)
KR (1) KR20010041019A (tr)
CN (1) CN1293576A (tr)
AU (1) AU748299B2 (tr)
BR (1) BR9908616A (tr)
CA (1) CA2320387A1 (tr)
EA (1) EA003512B1 (tr)
HU (1) HUP0101248A2 (tr)
ID (1) ID26247A (tr)
MY (1) MY120798A (tr)
NO (1) NO20004049L (tr)
NZ (1) NZ506280A (tr)
PL (1) PL342971A1 (tr)
TR (1) TR200002465T2 (tr)
TW (1) TW585770B (tr)
YU (1) YU51300A (tr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1187601E (pt) * 1999-06-07 2005-11-30 Altana Pharma Ag Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
KR20050005437A (ko) 2002-04-09 2005-01-13 플라멜 테크놀로지스 아목시실린의 변형 방출을 위한 마이크로캡슐 수성 현탁액형태의 경구 제약학적 제제
MXPA04009968A (es) 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
US7670627B2 (en) * 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
US20050281795A1 (en) * 2004-06-17 2005-12-22 Amano Enzyme Usa., Ltd. And Amano Enzyme,Inc. Controlled release formulations of enzymes, microorganisms, and antibodies with mucoadhesive polymers
US8252333B2 (en) 2006-01-26 2012-08-28 Jorge Cueto-Garcia Biodegradable, non-toxic biological adhesive for use in abdominal surgery
WO2007086078A2 (en) * 2006-01-30 2007-08-02 Panacea Biotec Ltd. Novel pharmaceutical compositions and process of preparation thereof
US20080279921A1 (en) * 2007-05-07 2008-11-13 Ceramoptec Industries, Inc. Gel-formulations of hydrophobic photosensitizers for mucosal applications
US8303573B2 (en) 2007-10-17 2012-11-06 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8707964B2 (en) * 2007-10-31 2014-04-29 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8789536B2 (en) 2007-10-17 2014-07-29 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US20090105561A1 (en) * 2007-10-17 2009-04-23 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Medical or veterinary digestive tract utilization systems and methods
US8808276B2 (en) * 2007-10-23 2014-08-19 The Invention Science Fund I, Llc Adaptive dispensation in a digestive tract
US8109920B2 (en) * 2007-10-31 2012-02-07 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US20090163894A1 (en) * 2007-10-31 2009-06-25 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Medical or veterinary digestive tract utilization systems and methods
US8333754B2 (en) * 2007-10-31 2012-12-18 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8808271B2 (en) * 2007-10-31 2014-08-19 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US20090137866A1 (en) * 2007-11-28 2009-05-28 Searete Llc, A Limited Liability Corporation Of The State Delaware Medical or veterinary digestive tract utilization systems and methods
EP2255794A1 (en) * 2009-05-29 2010-12-01 H e x a l Aktiengesellschaft Enteric coating
CA2774951C (en) 2009-09-24 2014-12-16 Allergan, Inc. Method of treating osteoporosis with a neurotoxin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5846019A (ja) * 1981-09-14 1983-03-17 Kanebo Ltd 持続性ニフエジピン製剤
DE4036757A1 (de) * 1990-11-17 1992-05-21 Bayer Ag Antazida-zubereitung mit verlaengerter magenverweilzeit
TW209174B (tr) 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
EP0995447A1 (en) 1993-09-09 2000-04-26 Takeda Chemical Industries, Ltd. Formulation comprising antibacterial substance and antiulcer substance
EP0752855B1 (en) * 1994-03-30 1999-06-09 Gs Development Ab Use of fatty acid esters as bioadhesive substances
JPH09104640A (ja) 1995-08-04 1997-04-22 Takeda Chem Ind Ltd 胃粘膜付着性組成物
EP0867191A4 (en) * 1995-11-27 2000-01-05 Yamanouchi Pharma Co Ltd MEDICINE COMPOSITION
JPH10167985A (ja) 1996-10-08 1998-06-23 Takeda Chem Ind Ltd 抗ヘリコバクター剤
ATE286715T1 (de) 1997-03-25 2005-01-15 Takeda Chemical Industries Ltd Gastrointestinale an der mucosa haftende pharmazeutische zusammensetzung

Also Published As

Publication number Publication date
ID26247A (id) 2000-12-07
NZ506280A (en) 2001-08-31
CA2320387A1 (en) 1999-09-30
AU748299B2 (en) 2002-05-30
AU2852499A (en) 1999-10-18
PL342971A1 (en) 2001-07-16
BR9908616A (pt) 2000-10-31
NO20004049L (no) 2000-10-03
KR20010041019A (ko) 2001-05-15
YU51300A (sh) 2002-09-19
TW585770B (en) 2004-05-01
EA200000973A1 (ru) 2001-02-26
HUP0101248A2 (hu) 2001-08-28
MY120798A (en) 2005-11-30
EA003512B1 (ru) 2003-06-26
EP1062955A1 (en) 2000-12-27
CN1293576A (zh) 2001-05-02
US6582720B1 (en) 2003-06-24
NO20004049D0 (no) 2000-08-11

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