TR200001621A2 - Yeni arilpiperazinilalkil-3(2H)-Piridaziononlar - Google Patents

Yeni arilpiperazinilalkil-3(2H)-Piridaziononlar

Info

Publication number
TR200001621A2
TR200001621A2 TR2000/01621A TR200001621A TR200001621A2 TR 200001621 A2 TR200001621 A2 TR 200001621A2 TR 2000/01621 A TR2000/01621 A TR 2000/01621A TR 200001621 A TR200001621 A TR 200001621A TR 200001621 A2 TR200001621 A2 TR 200001621A2
Authority
TR
Turkey
Prior art keywords
piridazionones
arylpiperazinilalkyl
radical
receptors
new
Prior art date
Application number
TR2000/01621A
Other languages
English (en)
Other versions
TR200001621A3 (tr
Inventor
Orjales Venero Aurelio
Garcia-Dominguez Neftal�
Original Assignee
Faes Fabrica Espa�Ola De Productos Quimicos Y Farmaceuticos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Faes Fabrica Espa�Ola De Productos Quimicos Y Farmaceuticos filed Critical Faes Fabrica Espa�Ola De Productos Quimicos Y Farmaceuticos
Publication of TR200001621A2 publication Critical patent/TR200001621A2/tr
Publication of TR200001621A3 publication Critical patent/TR200001621A3/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

R1'in metil veya fenil grubu, R2'nin bir hidrojen atomu veya metil grubu, n'nin 2 ila 4 arasi bir deger ve R3'ün metoksil, klorin, triflorometil gibi bir radikal ile ikame edilebilen bir naftil radikal veya bir fenil radikali oldugu genel formül (I): Yeni arilpiperazinilalkil-3(2H)-Piridaziononlari ve farmasötik olarak kabul edilebilir asit katki tuzlarinin bir tarifi verilmektedir. Bilesimler serotonin 5HT1A ve 5HT2 reseptörleri ve dopamin D2 reseptörleri için egilim göstermekte olup, antipisokotikler olarak faydali olabilirler.
TR2000/01621A 1999-06-04 2000-06-02 Yeni arilpiperazinilalkil-3(2H)-Piridaziononlar TR200001621A3 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009901239A ES2162731B1 (es) 1999-06-04 1999-06-04 Nuevas arilpiperacilnilalquil-3(2h)-piridacinonas.

Publications (2)

Publication Number Publication Date
TR200001621A2 true TR200001621A2 (tr) 2001-07-23
TR200001621A3 TR200001621A3 (tr) 2001-07-23

Family

ID=8308721

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01621A TR200001621A3 (tr) 1999-06-04 2000-06-02 Yeni arilpiperazinilalkil-3(2H)-Piridaziononlar

Country Status (15)

Country Link
US (1) US6413966B1 (tr)
EP (1) EP1057820A1 (tr)
JP (1) JP2001002659A (tr)
KR (1) KR20010049474A (tr)
AU (1) AU3780100A (tr)
BR (1) BR0002578A (tr)
CA (1) CA2310873A1 (tr)
ES (1) ES2162731B1 (tr)
HR (1) HRP20000370A2 (tr)
HU (1) HUP0002132A2 (tr)
IL (1) IL136507A0 (tr)
MX (1) MXPA00005428A (tr)
NO (1) NO20002837L (tr)
PL (1) PL340490A1 (tr)
TR (1) TR200001621A3 (tr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10036818A1 (de) * 2000-07-28 2002-02-07 Solvay Pharm Gmbh Neue N-Triazolylmethyl-Piperazinderivate als Neurokininrezeptor-Antagonisten
EP1408976B3 (en) 2001-07-20 2010-08-25 Psychogenics Inc. Treatment for attention-deficit hyperactivity disorder
CA3157396A1 (en) * 2019-12-19 2021-06-24 Universite De Strasbourg Sigma-1 receptor ligands and therapeutic uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
HU214320B (hu) * 1991-12-20 1998-03-02 EGIS Gyógyszergyár Rt. Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására
JP3670690B2 (ja) * 1993-10-04 2005-07-13 トーアエイヨー株式会社 ３−ピリダジノン誘導体、その製造法およびそれを含有する循環器官用剤
EP0875512A3 (en) * 1997-04-16 1999-04-07 Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. (Faes) New naphthylpiperazine derivatives with antipsychotic activity
PT1043317E (pt) * 1997-11-19 2009-05-11 Kowa Co Novos derivados de piridazina e fármacos que os contêm como ingrediente activo

Also Published As

Publication number Publication date
TR200001621A3 (tr) 2001-07-23
HU0002132D0 (en) 2000-08-28
ES2162731B1 (es) 2003-02-16
JP2001002659A (ja) 2001-01-09
HRP20000370A2 (en) 2001-06-30
HUP0002132A2 (hu) 2002-11-28
KR20010049474A (ko) 2001-06-15
EP1057820A1 (en) 2000-12-06
IL136507A0 (en) 2001-06-14
ES2162731A1 (es) 2002-01-01
MXPA00005428A (es) 2002-06-04
PL340490A1 (en) 2000-12-18
BR0002578A (pt) 2001-01-02
NO20002837D0 (no) 2000-06-02
CA2310873A1 (en) 2000-12-04
US6413966B1 (en) 2002-07-02
AU3780100A (en) 2000-12-07
NO20002837L (no) 2000-12-05

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