TR199902693T2 - Poli(sikloalifatik fosfoester) bilesiklerini içeren biyo-bozunabilir bilesimler, ürünler ve bunlarin kullanilmasi için yöntemler. - Google Patents
Poli(sikloalifatik fosfoester) bilesiklerini içeren biyo-bozunabilir bilesimler, ürünler ve bunlarin kullanilmasi için yöntemler.Info
- Publication number
- TR199902693T2 TR199902693T2 TR1999/02693T TR9902693T TR199902693T2 TR 199902693 T2 TR199902693 T2 TR 199902693T2 TR 1999/02693 T TR1999/02693 T TR 1999/02693T TR 9902693 T TR9902693 T TR 9902693T TR 199902693 T2 TR199902693 T2 TR 199902693T2
- Authority
- TR
- Turkey
- Prior art keywords
- biodegradable
- polymer
- compounds
- methods
- biologically active
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G79/00—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule
- C08G79/02—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule a linkage containing phosphorus
- C08G79/04—Phosphorus linked to oxygen or to oxygen and carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/924—Material characteristic
Abstract
(I) formülünde gösterilen tekrarlanan monomerik birimlere sahip olan bir polimeri içeren biyo-bozunabilir, akabilir ya da esnek polimer bilesimleri anlatilmistir, bu formülde, R ve R'nin her biri, bagimsiz olarak, düz ya da dalli alifatiktir, bu alifatik, bir ya da daha çok araya girmeyen ikame edici ile ya ikame edilmekte ya da edilmemektedir; L, bir iki degerli sikloalifatik grubudur; R", H, alkil, alkoksi, aril, ariloksi, heteroksiklik ya da heterosikloksiyi kapsayan gruptan seçilmektedir; ve n, 5'den 1,000'e kadardir, burada, bahsedilen biyo-bozunabilir polimer, biyo-bozunmadan önce ve biyo-bozunma üzerine biyo-uyumlu olmaktadir. Bir düzenlemede, R, R ya da R"nin bir ya da daha çogu biyolojik olarak aktif maddedir. Polimere ilave olarak bir biyolojik olarak aktif maddeyi ihtiva eden amorf bilesimler ve bilesimler kullanilarak biyolojik olarak aktif maddelerin kontrol edilebilir biçimde salinmasi için yöntemler de anlatilmistir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84134597A | 1997-04-30 | 1997-04-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199902693T2 true TR199902693T2 (tr) | 2000-04-21 |
Family
ID=25284634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1999/02693T TR199902693T2 (tr) | 1997-04-30 | 1998-04-30 | Poli(sikloalifatik fosfoester) bilesiklerini içeren biyo-bozunabilir bilesimler, ürünler ve bunlarin kullanilmasi için yöntemler. |
Country Status (15)
Country | Link |
---|---|
US (2) | US6403675B1 (tr) |
EP (1) | EP0980269A1 (tr) |
JP (1) | JP2002500640A (tr) |
KR (1) | KR20010020432A (tr) |
CN (1) | CN1258221A (tr) |
AU (1) | AU749644B2 (tr) |
BR (1) | BR9809017A (tr) |
CA (1) | CA2288014A1 (tr) |
HU (1) | HUP0001299A3 (tr) |
IL (1) | IL132487A0 (tr) |
NO (1) | NO995301L (tr) |
NZ (1) | NZ501184A (tr) |
PL (1) | PL336596A1 (tr) |
TR (1) | TR199902693T2 (tr) |
WO (1) | WO1998048859A1 (tr) |
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EP1117441A2 (en) * | 1998-10-02 | 2001-07-25 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly(phosphonate) and polyester-poly(phosphite) compositions, articles, and methods of using them |
US6419709B1 (en) | 1998-10-02 | 2002-07-16 | Guilford Pharmaceuticals, Inc. | Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same |
US6350464B1 (en) * | 1999-01-11 | 2002-02-26 | Guilford Pharmaceuticals, Inc. | Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same |
US6537585B1 (en) * | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
CN1196736C (zh) * | 1999-04-07 | 2005-04-13 | 纳幕尔杜邦公司 | 具有降低的甲醛气味的聚缩醛树脂 |
US20040038948A1 (en) * | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
WO2001068052A2 (en) * | 2000-03-10 | 2001-09-20 | Johns Hopkins University | Phosphate based biodegradable polymers |
US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
US20070141107A1 (en) * | 2000-03-15 | 2007-06-21 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
EP1299048A4 (en) * | 2000-06-28 | 2005-09-28 | Atul J Shukla | BIODEGRADABLE VEHICLES AND SYSTEMS FOR DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES |
AU2001269961A1 (en) | 2000-07-06 | 2002-01-21 | Guilford Pharmaceuticals | Improved polymers and polymerization processes |
AU2001270310A1 (en) * | 2000-07-07 | 2002-01-21 | Guilford Pharmaceuticals Inc. | Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same |
AU2001280597A1 (en) * | 2000-07-17 | 2002-01-30 | Guilford Pharmaceuticals Inc. | Compositions for sustained release of analgesic agents, and methods of making and using the same |
US20020198135A1 (en) * | 2000-10-12 | 2002-12-26 | Wenbin Dang | Compositions for release of radiosensitizers, and methods of making and using the same |
SG125885A1 (en) * | 2000-12-05 | 2006-10-30 | Univ Singapore | A polymer and nerve guide conduits formed thereof |
GB0100624D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds VII |
US20030032675A1 (en) * | 2001-02-15 | 2003-02-13 | Franz G. Andrew | Manufacture of thyroid hormone tablets having consistent active moiety amounts |
US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
JP2004525109A (ja) * | 2001-02-15 | 2004-08-19 | キング・ファーマシューティカルズ・インコーポレイティッド | 安定化された甲状腺ホルモン医薬組成物、及びその製法 |
US20030224047A1 (en) * | 2001-02-15 | 2003-12-04 | Franz G. Andrew | Levothyroxine compositions and methods |
US7345138B2 (en) * | 2001-05-14 | 2008-03-18 | Johns Hopkins Singapore Pte Ltd. | Biodegradable polyphosphates for controlled release of bioactive substances |
WO2003000776A1 (en) * | 2001-05-14 | 2003-01-03 | Johns Hopkins Singapore Pte Ltd | Biodegradable polyphosphoramidates for controlled release of bioactive substances |
CA2449978A1 (en) * | 2001-06-15 | 2002-12-27 | Johns Hopkins Singapore Pte Ltd | Biofunctional fibers |
US20030134892A1 (en) * | 2001-07-19 | 2003-07-17 | Wenbin Dang | Compositions for treatment of head and neck cancers, and methods of making and using the same |
US20030133903A1 (en) * | 2001-07-19 | 2003-07-17 | Wenbin Dang | Compositions for treatment of prostate cancers and methods of making and using the same |
US20030198671A1 (en) * | 2001-08-10 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique plasma AUC properties |
US20030190349A1 (en) * | 2001-08-10 | 2003-10-09 | Franz G. Andrew | Methods of stabilizing pharmaceutical compositions |
US20030180353A1 (en) * | 2001-08-10 | 2003-09-25 | Franz G. Andrew | Stabilized pharmaceutical compositions |
US20030198667A1 (en) * | 2001-08-10 | 2003-10-23 | Franz Andrew G. | Methods of producing dispersible pharmaceutical compositions |
US20030203967A1 (en) * | 2001-08-14 | 2003-10-30 | Franz G. Andrew | Levothyroxine compositions having unique Tmax properties |
US20030195253A1 (en) * | 2001-08-14 | 2003-10-16 | Franz G. Andrew | Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration |
US20030198672A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique triidothyronine plasma AUC properties |
US20030199587A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique Cmax properties |
US20030165564A1 (en) * | 2001-10-29 | 2003-09-04 | Franz G. Andrew | Levothyroxine compositions having unique triiodothyronine Tmax properties |
AU2003202255A1 (en) * | 2002-01-09 | 2003-07-30 | Guilford Pharmaceuticals, Inc. | Compositions for treatment of central nervous system neoplasms, and methods of making and using the same |
PT1509256E (pt) * | 2002-05-24 | 2009-10-15 | Angiotech Int Ag | Composições e métodos de revestimento de implantes médicos |
US8313760B2 (en) | 2002-05-24 | 2012-11-20 | Angiotech International Ag | Compositions and methods for coating medical implants |
JP4184158B2 (ja) * | 2003-06-05 | 2008-11-19 | 旭化成ケミカルズ株式会社 | ホスホニトリル酸エステルの製造法 |
WO2005013810A2 (en) * | 2003-08-07 | 2005-02-17 | University Of Florida | Biodegradable embolic agents |
EP1687043A2 (en) * | 2003-11-20 | 2006-08-09 | Angiotech International Ag | Electrical devices and anti-scarring agents |
US20050209664A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Electrical devices and anti-scarring agents |
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WO2005097833A1 (en) * | 2004-04-05 | 2005-10-20 | University Of Florida Research Foundation, Inc. | Functionalized organic oligomers using homogeneous modification method for molecular binding |
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UA54505C2 (uk) * | 1997-04-03 | 2003-03-17 | Гілфорд Фармасьютікалз Інк. | Полімери, що біологічно розкладаються, зшиті фосфатами, композиції, вироби і способи для їх виготовлення і використання |
-
1998
- 1998-04-30 PL PL98336596A patent/PL336596A1/xx unknown
- 1998-04-30 US US09/070,204 patent/US6403675B1/en not_active Expired - Lifetime
- 1998-04-30 NZ NZ501184A patent/NZ501184A/xx unknown
- 1998-04-30 CN CN98805636A patent/CN1258221A/zh active Pending
- 1998-04-30 EP EP98918959A patent/EP0980269A1/en not_active Withdrawn
- 1998-04-30 KR KR1019997010061A patent/KR20010020432A/ko not_active Application Discontinuation
- 1998-04-30 HU HU0001299A patent/HUP0001299A3/hu unknown
- 1998-04-30 TR TR1999/02693T patent/TR199902693T2/tr unknown
- 1998-04-30 IL IL13248798A patent/IL132487A0/xx unknown
- 1998-04-30 WO PCT/US1998/009185 patent/WO1998048859A1/en not_active Application Discontinuation
- 1998-04-30 JP JP54746098A patent/JP2002500640A/ja active Pending
- 1998-04-30 CA CA002288014A patent/CA2288014A1/en not_active Abandoned
- 1998-04-30 AU AU71771/98A patent/AU749644B2/en not_active Ceased
- 1998-04-30 BR BR9809017-8A patent/BR9809017A/pt not_active IP Right Cessation
-
1999
- 1999-10-29 NO NO995301A patent/NO995301L/no not_active Application Discontinuation
-
2001
- 2001-12-04 US US10/011,570 patent/US6800672B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6403675B1 (en) | 2002-06-11 |
NZ501184A (en) | 2002-08-28 |
KR20010020432A (ko) | 2001-03-15 |
WO1998048859A1 (en) | 1998-11-05 |
NO995301D0 (no) | 1999-10-29 |
JP2002500640A (ja) | 2002-01-08 |
HUP0001299A3 (en) | 2001-09-28 |
AU749644B2 (en) | 2002-06-27 |
US6800672B2 (en) | 2004-10-05 |
US20020137814A1 (en) | 2002-09-26 |
CA2288014A1 (en) | 1998-11-05 |
IL132487A0 (en) | 2001-03-19 |
PL336596A1 (en) | 2000-07-03 |
NO995301L (no) | 1999-12-30 |
CN1258221A (zh) | 2000-06-28 |
AU7177198A (en) | 1998-11-24 |
HUP0001299A2 (hu) | 2001-05-28 |
BR9809017A (pt) | 2002-01-02 |
EP0980269A1 (en) | 2000-02-23 |
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