TR199900493T2 - 1-Butil-4-Piperidinilmetilamin'in hazirlanmasi. - Google Patents

1-Butil-4-Piperidinilmetilamin'in hazirlanmasi.

Info

Publication number
TR199900493T2
TR199900493T2 TR1999/00493T TR9900493T TR199900493T2 TR 199900493 T2 TR199900493 T2 TR 199900493T2 TR 1999/00493 T TR1999/00493 T TR 1999/00493T TR 9900493 T TR9900493 T TR 9900493T TR 199900493 T2 TR199900493 T2 TR 199900493T2
Authority
TR
Turkey
Prior art keywords
butyl
piperidinilmetilamine
hazrlanmas
followed
isonipectolamide
Prior art date
Application number
TR1999/00493T
Other languages
English (en)
Inventor
Fedouloff Michael
William Guest David
Elizabeth Smith Gillian
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of TR199900493T2 publication Critical patent/TR199900493T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Optical Couplings Of Light Guides (AREA)

Abstract

i) Izonipektoamidin N-butil türevini vermek üzere 1-bromobutanin ve izonipektoamidin reaksiyonunu, ve ardindan da, ii) LiA1H4 ile redüksiyonu içeren ve i) ve ii) reaksiyonlarinin solvent olarak toluen içinde gerçeklestirilmesi ile karakterize edilen, 1-butil-4-piperidinilmetilamin'in hazirlanmasi için bir proses.
TR1999/00493T 1996-09-11 1997-09-09 1-Butil-4-Piperidinilmetilamin'in hazirlanmasi. TR199900493T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9618967.5A GB9618967D0 (en) 1996-09-11 1996-09-11 Pharmaceuticals

Publications (1)

Publication Number Publication Date
TR199900493T2 true TR199900493T2 (tr) 1999-06-21

Family

ID=10799764

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/00493T TR199900493T2 (tr) 1996-09-11 1997-09-09 1-Butil-4-Piperidinilmetilamin'in hazirlanmasi.

Country Status (30)

Country Link
US (1) US6331631B1 (tr)
EP (1) EP0927163B1 (tr)
JP (2) JP3748570B2 (tr)
KR (1) KR100525703B1 (tr)
CN (1) CN1102927C (tr)
AR (1) AR008174A1 (tr)
AT (1) ATE358121T1 (tr)
AU (1) AU725210B2 (tr)
BR (1) BR9712014A (tr)
CA (1) CA2266468C (tr)
CO (1) CO4930263A1 (tr)
CY (1) CY2590B2 (tr)
CZ (1) CZ290932B6 (tr)
DE (1) DE69737529T2 (tr)
DK (1) DK0927163T3 (tr)
ES (1) ES2285732T3 (tr)
GB (1) GB9618967D0 (tr)
HK (1) HK1020963A1 (tr)
HU (1) HUP9904155A3 (tr)
IL (1) IL128785A0 (tr)
NO (1) NO312587B1 (tr)
NZ (1) NZ334272A (tr)
PL (1) PL191373B1 (tr)
PT (1) PT927163E (tr)
SA (1) SA97180387B1 (tr)
SI (1) SI0927163T1 (tr)
TR (1) TR199900493T2 (tr)
TW (1) TW432048B (tr)
WO (1) WO1998011067A1 (tr)
ZA (1) ZA978087B (tr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618967D0 (en) * 1996-09-11 1996-10-23 Smithkline Beecham Plc Pharmaceuticals
US20020091271A1 (en) 1998-07-16 2002-07-11 Smithkline Beecham Plc Process for the preparation of an indole derivative
GB0211230D0 (en) 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
CN104557672B (zh) * 2015-01-26 2016-09-21 湖南华腾制药有限公司 一种1位取代哌啶衍生物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5821904B2 (ja) * 1975-04-04 1983-05-04 住友化学工業株式会社 シンキナメタノ−アントラセンユウドウタイノセイゾウホウホウ
ZA899436B (en) * 1988-12-12 1990-08-29 Ciba Geigy Piperidine derivatives
AT394715B (de) * 1990-08-14 1992-06-10 Chemie Linz Gmbh Verfahren zur n-alkylierung von harnstoffen
WO1993005038A1 (en) * 1991-09-12 1993-03-18 Smithkline Beecham Plc 5-ht4 receptor antagonists
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
AP401A (en) * 1992-03-12 1995-08-29 Smithkline Beecham Plc Condensed indole derivatives as 5H4-receptor antagonists.
GB9209687D0 (en) * 1992-05-06 1992-06-17 Smithkline Beecham Plc Novel process
JPH08502283A (ja) * 1992-10-16 1996-03-12 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５−ｈｔ▲下４▼レセプターアンタゴニスト用の縮合環系ｎ−アルキルピペリジニル−４−メチルカルボン酸エステル／アミド
DE4427836A1 (de) * 1994-08-05 1996-02-08 Hoechst Ag Verbindungen aus der Reihe der Phosphane, Verfahren zu ihrer Herstellung sowie ihre Verwendung
KR19990022096A (ko) * 1995-05-31 1999-03-25 쇼다 오사무 모노시클릭 아미노기를 갖는 인다졸 유도체
GB9618967D0 (en) * 1996-09-11 1996-10-23 Smithkline Beecham Plc Pharmaceuticals

Also Published As

Publication number Publication date
AR008174A1 (es) 1999-12-09
CZ80999A3 (cs) 1999-11-17
KR100525703B1 (ko) 2005-11-03
PL332088A1 (en) 1999-08-30
AU725210B2 (en) 2000-10-05
BR9712014A (pt) 1999-08-24
CA2266468A1 (en) 1998-03-19
KR20000038041A (ko) 2000-07-05
HUP9904155A2 (hu) 2000-05-28
CN1230179A (zh) 1999-09-29
GB9618967D0 (en) 1996-10-23
TW432048B (en) 2001-05-01
CA2266468C (en) 2005-10-25
NO991148D0 (no) 1999-03-10
CO4930263A1 (es) 2000-06-27
IL128785A0 (en) 2000-01-31
DK0927163T3 (da) 2007-08-06
NO312587B1 (no) 2002-06-03
SA97180387B1 (ar) 2006-11-04
ES2285732T3 (es) 2007-11-16
NO991148L (no) 1999-03-10
EP0927163B1 (en) 2007-03-28
HK1020963A1 (en) 2000-05-26
AU4776497A (en) 1998-04-02
ATE358121T1 (de) 2007-04-15
CZ290932B6 (cs) 2002-11-13
WO1998011067A1 (en) 1998-03-19
PT927163E (pt) 2007-07-06
ZA978087B (en) 1999-03-09
JP2005220126A (ja) 2005-08-18
CY2590B2 (en) 2009-11-04
DE69737529D1 (de) 2007-05-10
EP0927163A1 (en) 1999-07-07
SI0927163T1 (sl) 2007-08-31
PL191373B1 (pl) 2006-05-31
DE69737529T2 (de) 2008-01-31
NZ334272A (en) 2000-08-25
JP2001500148A (ja) 2001-01-09
CN1102927C (zh) 2003-03-12
US6331631B1 (en) 2001-12-18
HUP9904155A3 (en) 2001-01-29
JP3748570B2 (ja) 2006-02-22

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