DE69737529D1 - Herstellung von 1-butyl-4-piperidinylmethylamin - Google Patents

Herstellung von 1-butyl-4-piperidinylmethylamin

Info

Publication number
DE69737529D1
DE69737529D1 DE69737529T DE69737529T DE69737529D1 DE 69737529 D1 DE69737529 D1 DE 69737529D1 DE 69737529 T DE69737529 T DE 69737529T DE 69737529 T DE69737529 T DE 69737529T DE 69737529 D1 DE69737529 D1 DE 69737529D1
Authority
DE
Germany
Prior art keywords
methylmethylamine
piperidin
butyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69737529T
Other languages
English (en)
Other versions
DE69737529T2 (de
Inventor
Michael Fedouloff
David William Guest
Gillian Elizabeth Smith
John Bryce Strachan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE69737529D1 publication Critical patent/DE69737529D1/de
Publication of DE69737529T2 publication Critical patent/DE69737529T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69737529T 1996-09-11 1997-09-09 Herstellung von 1-butyl-4-piperidinylmethylamin Expired - Lifetime DE69737529T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9618967.5A GB9618967D0 (en) 1996-09-11 1996-09-11 Pharmaceuticals
GB9618967 1996-09-11
PCT/EP1997/005167 WO1998011067A1 (en) 1996-09-11 1997-09-09 Preparation of 1-butyl-4-piperidinylmethylamine

Publications (2)

Publication Number Publication Date
DE69737529D1 true DE69737529D1 (de) 2007-05-10
DE69737529T2 DE69737529T2 (de) 2008-01-31

Family

ID=10799764

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737529T Expired - Lifetime DE69737529T2 (de) 1996-09-11 1997-09-09 Herstellung von 1-butyl-4-piperidinylmethylamin

Country Status (30)

Country Link
US (1) US6331631B1 (de)
EP (1) EP0927163B1 (de)
JP (2) JP3748570B2 (de)
KR (1) KR100525703B1 (de)
CN (1) CN1102927C (de)
AR (1) AR008174A1 (de)
AT (1) ATE358121T1 (de)
AU (1) AU725210B2 (de)
BR (1) BR9712014A (de)
CA (1) CA2266468C (de)
CO (1) CO4930263A1 (de)
CY (1) CY2590B2 (de)
CZ (1) CZ290932B6 (de)
DE (1) DE69737529T2 (de)
DK (1) DK0927163T3 (de)
ES (1) ES2285732T3 (de)
GB (1) GB9618967D0 (de)
HK (1) HK1020963A1 (de)
HU (1) HUP9904155A3 (de)
IL (1) IL128785A0 (de)
NO (1) NO312587B1 (de)
NZ (1) NZ334272A (de)
PL (1) PL191373B1 (de)
PT (1) PT927163E (de)
SA (1) SA97180387B1 (de)
SI (1) SI0927163T1 (de)
TR (1) TR199900493T2 (de)
TW (1) TW432048B (de)
WO (1) WO1998011067A1 (de)
ZA (1) ZA978087B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618967D0 (en) * 1996-09-11 1996-10-23 Smithkline Beecham Plc Pharmaceuticals
US20020091271A1 (en) 1998-07-16 2002-07-11 Smithkline Beecham Plc Process for the preparation of an indole derivative
GB0211230D0 (en) 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
CN104557672B (zh) * 2015-01-26 2016-09-21 湖南华腾制药有限公司 一种1位取代哌啶衍生物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5821904B2 (ja) * 1975-04-04 1983-05-04 住友化学工業株式会社 シンキナメタノ−アントラセンユウドウタイノセイゾウホウホウ
ZA899436B (en) * 1988-12-12 1990-08-29 Ciba Geigy Piperidine derivatives
AT394715B (de) * 1990-08-14 1992-06-10 Chemie Linz Gmbh Verfahren zur n-alkylierung von harnstoffen
HUT70154A (en) * 1991-09-12 1995-09-28 Smithkline Beecham Plc 5-ht4 receptor antagonists and pharmaceutical compositions containing them
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
CZ286194B6 (cs) * 1992-03-12 2000-02-16 Smithkline Beecham P.L.C. Kondenzované indolové deriváty, způsob jejich výroby, farmaceutické prostředky s jejich obsahem a použití derivátů pro výrobu farmaceutických prostředků
GB9209687D0 (en) * 1992-05-06 1992-06-17 Smithkline Beecham Plc Novel process
WO1994008965A1 (en) * 1992-10-16 1994-04-28 Smithkline Beecham Plc N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-ht4 receptor antagonists
DE4427836A1 (de) * 1994-08-05 1996-02-08 Hoechst Ag Verbindungen aus der Reihe der Phosphane, Verfahren zu ihrer Herstellung sowie ihre Verwendung
DE69627323T2 (de) 1995-05-31 2004-01-15 Nisshin Seifun Group Inc Indazolderivate mit einer cyclischen aminogruppe
GB9618967D0 (en) * 1996-09-11 1996-10-23 Smithkline Beecham Plc Pharmaceuticals

Also Published As

Publication number Publication date
PT927163E (pt) 2007-07-06
HUP9904155A2 (hu) 2000-05-28
ATE358121T1 (de) 2007-04-15
KR20000038041A (ko) 2000-07-05
CA2266468C (en) 2005-10-25
WO1998011067A1 (en) 1998-03-19
ES2285732T3 (es) 2007-11-16
ZA978087B (en) 1999-03-09
SI0927163T1 (sl) 2007-08-31
DE69737529T2 (de) 2008-01-31
EP0927163A1 (de) 1999-07-07
KR100525703B1 (ko) 2005-11-03
JP2001500148A (ja) 2001-01-09
SA97180387B1 (ar) 2006-11-04
BR9712014A (pt) 1999-08-24
PL332088A1 (en) 1999-08-30
NO991148L (no) 1999-03-10
HUP9904155A3 (en) 2001-01-29
CZ80999A3 (cs) 1999-11-17
JP3748570B2 (ja) 2006-02-22
JP2005220126A (ja) 2005-08-18
EP0927163B1 (de) 2007-03-28
HK1020963A1 (en) 2000-05-26
AU725210B2 (en) 2000-10-05
AU4776497A (en) 1998-04-02
PL191373B1 (pl) 2006-05-31
US6331631B1 (en) 2001-12-18
CO4930263A1 (es) 2000-06-27
CY2590B2 (en) 2009-11-04
NZ334272A (en) 2000-08-25
AR008174A1 (es) 1999-12-09
CN1230179A (zh) 1999-09-29
TW432048B (en) 2001-05-01
TR199900493T2 (xx) 1999-06-21
IL128785A0 (en) 2000-01-31
DK0927163T3 (da) 2007-08-06
CA2266468A1 (en) 1998-03-19
NO312587B1 (no) 2002-06-03
GB9618967D0 (en) 1996-10-23
CN1102927C (zh) 2003-03-12
CZ290932B6 (cs) 2002-11-13
NO991148D0 (no) 1999-03-10

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Legal Events

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8364 No opposition during term of opposition