KR840001999A - 벤조퀴놀리진의 제조방법 - Google Patents
벤조퀴놀리진의 제조방법 Download PDFInfo
- Publication number
- KR840001999A KR840001999A KR1019820004513A KR820004513A KR840001999A KR 840001999 A KR840001999 A KR 840001999A KR 1019820004513 A KR1019820004513 A KR 1019820004513A KR 820004513 A KR820004513 A KR 820004513A KR 840001999 A KR840001999 A KR 840001999A
- Authority
- KR
- South Korea
- Prior art keywords
- quinolizine
- hexahydro
- benzo
- methyl
- addition salt
- Prior art date
Links
- SSSYOIPHXANRMO-UHFFFAOYSA-N 4h-benzo[a]quinolizine Chemical compound C1=CC=C2C3=CC=CCN3C=CC2=C1 SSSYOIPHXANRMO-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- FKOZPUORKCHONH-UHFFFAOYSA-N 2-methylpropane-1-sulfonic acid Chemical class CC(C)CS(O)(=O)=O FKOZPUORKCHONH-UHFFFAOYSA-N 0.000 claims 1
- 238000010531 catalytic reduction reaction Methods 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000002588 toxic effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
- C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 이소부탄설폰산의 반응성 유도체를 2β-메틸아미노-1,3,4,6,7,11b-헥사하이드로-2H-벤조[a] 퀴놀리진과 반응시키거나 또는 N-메틸-N-(1,3,4,6,7,11bα-헥사하이드로-2H-벤조[a] 퀴놀리진-2β-일)-2-메틸-2-프로펜-1-설폰아미드 또는 기의 산부가염을 접촉 환원하고 필요하다면 유리염기를 약제학적으로 무독한 산부가염으로 전환시킴을 특징으로 하여, N-메틸-N-(1,3,4,6,7,11b α-헥사하이드로-2H-벤조[a]-퀴놀리진-2β-일)-이소-부탄설폰아미드 또는 그의 약제학적으로 무독한 산부가염을 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8130350 | 1981-10-07 | ||
GB30350 | 1981-10-07 | ||
GB8130350 | 1981-10-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR840001999A true KR840001999A (ko) | 1984-06-11 |
KR880002004B1 KR880002004B1 (ko) | 1988-10-11 |
Family
ID=10525019
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR8204513A KR880002004B1 (ko) | 1981-10-07 | 1982-10-07 | 벤조퀴놀리진의 제조방법 |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0079123B1 (ko) |
JP (1) | JPS5872581A (ko) |
KR (1) | KR880002004B1 (ko) |
AT (1) | ATE15371T1 (ko) |
AU (1) | AU554777B2 (ko) |
CA (1) | CA1173038A (ko) |
DE (1) | DE3266047D1 (ko) |
DK (1) | DK159443C (ko) |
GR (1) | GR78037B (ko) |
IE (1) | IE54048B1 (ko) |
PH (1) | PH17333A (ko) |
ZA (1) | ZA826826B (ko) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1513824A (en) * | 1975-05-22 | 1978-06-14 | Wyeth John & Brother Ltd | 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative |
GB1577187A (en) * | 1977-12-14 | 1980-10-22 | Wyeth John & Brother Ltd | 2-sulphamamido-1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizimes |
IE51467B1 (en) * | 1980-08-28 | 1986-12-24 | Wyeth John & Brother Ltd | Benzoquinolizines |
ZA815420B (en) * | 1980-08-28 | 1983-03-30 | Wyeth John & Brother Ltd | Benzoquinolizines |
-
1982
- 1982-09-14 IE IE2240/82A patent/IE54048B1/en not_active IP Right Cessation
- 1982-09-15 AU AU88426/82A patent/AU554777B2/en not_active Ceased
- 1982-09-15 CA CA000411483A patent/CA1173038A/en not_active Expired
- 1982-09-16 ZA ZA826826A patent/ZA826826B/xx unknown
- 1982-09-20 GR GR69317A patent/GR78037B/el unknown
- 1982-09-30 AT AT82305194T patent/ATE15371T1/de not_active IP Right Cessation
- 1982-09-30 EP EP82305194A patent/EP0079123B1/en not_active Expired
- 1982-09-30 DE DE8282305194T patent/DE3266047D1/de not_active Expired
- 1982-10-01 PH PH27945A patent/PH17333A/en unknown
- 1982-10-05 DK DK442782A patent/DK159443C/da not_active IP Right Cessation
- 1982-10-07 JP JP57177467A patent/JPS5872581A/ja active Pending
- 1982-10-07 KR KR8204513A patent/KR880002004B1/ko active
Also Published As
Publication number | Publication date |
---|---|
EP0079123B1 (en) | 1985-09-04 |
GR78037B (ko) | 1984-09-26 |
DK159443C (da) | 1991-04-02 |
EP0079123A1 (en) | 1983-05-18 |
AU554777B2 (en) | 1986-09-04 |
ZA826826B (en) | 1984-04-25 |
ATE15371T1 (de) | 1985-09-15 |
IE54048B1 (en) | 1989-05-24 |
CA1173038A (en) | 1984-08-21 |
JPS5872581A (ja) | 1983-04-30 |
DK159443B (da) | 1990-10-15 |
IE822240L (en) | 1983-04-07 |
DE3266047D1 (de) | 1985-10-10 |
KR880002004B1 (ko) | 1988-10-11 |
AU8842682A (en) | 1983-04-14 |
PH17333A (en) | 1984-08-01 |
DK442782A (da) | 1983-04-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR860001110A (ko) | 항균제 ⅱ의 제법 | |
FI873157A (fi) | Spaerrkonstruktioner foer gas. | |
DE3686677T2 (de) | Isoxazol- und furanderivate, verfahren zu ihrer herstellung und ihre verwendung als antivirale mittel. | |
DE68902916T2 (de) | Herstellung von quecksilberfreiem synthesegas, reduktionsgas oder brenngas. | |
DE3770135D1 (de) | Gasturbinenanlage. | |
DE3781453D1 (de) | Waessrige zusammensetzung aus einem sulfonierten phenol, einem amin und einem gerbesalz, ihre herstellung und verwendung als gerbstoff. | |
KR850001149A (ko) | 2-3차-부틸아미노-3'-클로로프로피오페논 말레에이트의 제조방법 | |
ATE77371T1 (de) | 3-carbonyl-1-aminoalkyl-1h-indole, verwendbar als analgetika und ihre herstellung. | |
FI861189A0 (fi) | Foerstaerkningsfoerfarande och -anordning foer gas. | |
KR830005168A (ko) | 5-(디하이드록시페녹시)테트라졸의 제조방법 | |
KR840001999A (ko) | 벤조퀴놀리진의 제조방법 | |
BE848697A (fr) | Reactif en solution stable pour la recherche de l'oxydase, | |
OA06855A (fr) | Système d'amarrage. | |
FI864281A0 (fi) | Foerfarande foer avlaegsnande av svavelinne- svavelinnehaollet i en uttunnad svaveldioxidhaltig gas. | |
KR830010091A (ko) | 구연산 나프티드로푸릴의 제조방법 | |
FI872907A0 (fi) | Luftare foer infoerande av gas i vaetskor. | |
ATE115565T1 (de) | 2-halogensubstituierte n-indolylethyl- sulfonsäureamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln. | |
JPS5376631A (en) | Delivery sectioning system | |
KR830004247A (ko) | 5-아미노-[3,4'-비피리딘]-6(1H)-one-1'-산화물 또는 그의 산부가염의 제조방법 | |
NL185953C (nl) | Gebalanceerde drager voor bijvoorbeeld een lamp, loep of dergelijke. | |
KR830004331A (ko) | 스테리일 글르코사이드 유도체의 제조 방법 | |
KR830001927A (ko) | 비스 모라노린 유도체의 제조 방법 | |
JPS5288914A (en) | Magnetic float-up vehicke system | |
KR910012236A (ko) | 판크레아틴의 제조방법 | |
MA18907A1 (fr) | Nouvelles imines derivees de l'amino-5 benzodioxole-1,3 utilisees comme medicaments |