DK159443C - Analogifremgangsmaade til fremstilling af n-methyl-n-(1,3,4,6,7,11balfa-hexahydro-2h-benzooeaaaquinolizin-2beta-yl)-isobutan-sulfonamid samt farmaceutisk acceptable salte heraf - Google Patents
Analogifremgangsmaade til fremstilling af n-methyl-n-(1,3,4,6,7,11balfa-hexahydro-2h-benzooeaaaquinolizin-2beta-yl)-isobutan-sulfonamid samt farmaceutisk acceptable salte herafInfo
- Publication number
- DK159443C DK159443C DK442782A DK442782A DK159443C DK 159443 C DK159443 C DK 159443C DK 442782 A DK442782 A DK 442782A DK 442782 A DK442782 A DK 442782A DK 159443 C DK159443 C DK 159443C
- Authority
- DK
- Denmark
- Prior art keywords
- hexahydro
- methyl
- benzooeaaaquinolizin
- 11balfa
- saltable
- Prior art date
Links
- 239000001282 iso-butane Substances 0.000 title 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 102000030484 alpha-2 Adrenergic Receptor Human genes 0.000 abstract 2
- 108020004101 alpha-2 Adrenergic Receptor Proteins 0.000 abstract 2
- 230000003042 antagnostic effect Effects 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 102000030619 alpha-1 Adrenergic Receptor Human genes 0.000 abstract 1
- 108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
- C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8130350 | 1981-10-07 | ||
| GB8130350 | 1981-10-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK442782A DK442782A (da) | 1983-04-08 |
| DK159443B DK159443B (da) | 1990-10-15 |
| DK159443C true DK159443C (da) | 1991-04-02 |
Family
ID=10525019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK442782A DK159443C (da) | 1981-10-07 | 1982-10-05 | Analogifremgangsmaade til fremstilling af n-methyl-n-(1,3,4,6,7,11balfa-hexahydro-2h-benzooeaaaquinolizin-2beta-yl)-isobutan-sulfonamid samt farmaceutisk acceptable salte heraf |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0079123B1 (da) |
| JP (1) | JPS5872581A (da) |
| KR (1) | KR880002004B1 (da) |
| AT (1) | ATE15371T1 (da) |
| AU (1) | AU554777B2 (da) |
| CA (1) | CA1173038A (da) |
| DE (1) | DE3266047D1 (da) |
| DK (1) | DK159443C (da) |
| GR (1) | GR78037B (da) |
| IE (1) | IE54048B1 (da) |
| PH (1) | PH17333A (da) |
| ZA (1) | ZA826826B (da) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1513824A (en) * | 1975-05-22 | 1978-06-14 | Wyeth John & Brother Ltd | 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative |
| GB1577187A (en) * | 1977-12-14 | 1980-10-22 | Wyeth John & Brother Ltd | 2-sulphamamido-1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizimes |
| ZA815420B (en) * | 1980-08-28 | 1983-03-30 | Wyeth John & Brother Ltd | Benzoquinolizines |
| IE51467B1 (en) * | 1980-08-28 | 1986-12-24 | Wyeth John & Brother Ltd | Benzoquinolizines |
-
1982
- 1982-09-14 IE IE2240/82A patent/IE54048B1/en not_active IP Right Cessation
- 1982-09-15 CA CA000411483A patent/CA1173038A/en not_active Expired
- 1982-09-15 AU AU88426/82A patent/AU554777B2/en not_active Ceased
- 1982-09-16 ZA ZA826826A patent/ZA826826B/xx unknown
- 1982-09-20 GR GR69317A patent/GR78037B/el unknown
- 1982-09-30 DE DE8282305194T patent/DE3266047D1/de not_active Expired
- 1982-09-30 AT AT82305194T patent/ATE15371T1/de not_active IP Right Cessation
- 1982-09-30 EP EP82305194A patent/EP0079123B1/en not_active Expired
- 1982-10-01 PH PH27945A patent/PH17333A/en unknown
- 1982-10-05 DK DK442782A patent/DK159443C/da not_active IP Right Cessation
- 1982-10-07 KR KR8204513A patent/KR880002004B1/ko not_active Expired
- 1982-10-07 JP JP57177467A patent/JPS5872581A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GR78037B (da) | 1984-09-26 |
| DK442782A (da) | 1983-04-08 |
| ZA826826B (en) | 1984-04-25 |
| ATE15371T1 (de) | 1985-09-15 |
| KR880002004B1 (ko) | 1988-10-11 |
| EP0079123A1 (en) | 1983-05-18 |
| JPS5872581A (ja) | 1983-04-30 |
| IE822240L (en) | 1983-04-07 |
| EP0079123B1 (en) | 1985-09-04 |
| AU8842682A (en) | 1983-04-14 |
| CA1173038A (en) | 1984-08-21 |
| PH17333A (en) | 1984-08-01 |
| IE54048B1 (en) | 1989-05-24 |
| AU554777B2 (en) | 1986-09-04 |
| DE3266047D1 (de) | 1985-10-10 |
| DK159443B (da) | 1990-10-15 |
| KR840001999A (ko) | 1984-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |