TR199801380T2 - Hidroksamik asit temelli kollajenaz �nleyicileri. - Google Patents

Hidroksamik asit temelli kollajenaz �nleyicileri.

Info

Publication number
TR199801380T2
TR199801380T2 TR1998/01380T TR9801380T TR199801380T2 TR 199801380 T2 TR199801380 T2 TR 199801380T2 TR 1998/01380 T TR1998/01380 T TR 1998/01380T TR 9801380 T TR9801380 T TR 9801380T TR 199801380 T2 TR199801380 T2 TR 199801380T2
Authority
TR
Turkey
Prior art keywords
hydroxamic acid
collagenase inhibitors
based collagenase
alkenyl
aryl
Prior art date
Application number
TR1998/01380T
Other languages
English (en)
Turkish (tr)
Inventor
Bailey Stuart
Richard Buckle Derek
Faller Andrew
Glynn Smith David
Original Assignee
Smithkline Beecham Plc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc. filed Critical Smithkline Beecham Plc.
Publication of TR199801380T2 publication Critical patent/TR199801380T2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/34Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TR1998/01380T 1996-01-17 1997-01-14 Hidroksamik asit temelli kollajenaz �nleyicileri. TR199801380T2 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9601041.8A GB9601041D0 (en) 1996-01-17 1996-01-17 Novel compounds

Publications (1)

Publication Number Publication Date
TR199801380T2 true TR199801380T2 (xx) 1998-10-21

Family

ID=10787226

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/01380T TR199801380T2 (xx) 1996-01-17 1997-01-14 Hidroksamik asit temelli kollajenaz �nleyicileri.

Country Status (19)

Country Link
EP (1) EP0912545A1 (no)
JP (1) JP2000503312A (no)
KR (1) KR19990077325A (no)
CN (1) CN1213368A (no)
AR (1) AR005472A1 (no)
AU (1) AU725056B2 (no)
BR (1) BR9707024A (no)
CA (1) CA2242913A1 (no)
CZ (1) CZ222498A3 (no)
GB (1) GB9601041D0 (no)
HU (1) HUP9901022A3 (no)
IL (1) IL125381A0 (no)
NO (1) NO983283L (no)
NZ (1) NZ326352A (no)
PL (1) PL327820A1 (no)
TR (1) TR199801380T2 (no)
TW (1) TW462967B (no)
WO (1) WO1997026257A1 (no)
ZA (1) ZA97345B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
GB9609795D0 (en) * 1996-05-10 1996-07-17 Smithkline Beecham Plc Novel compounds
AU1960100A (en) * 1999-01-06 2000-07-24 Mcmaster University Method of preventing immune and hypersensitivity reactions
GB9922825D0 (en) * 1999-09-25 1999-11-24 Smithkline Beecham Biolog Medical use
WO2002006227A1 (fr) * 2000-07-18 2002-01-24 Chugai Seiyaku Kabushiki Kaisha Inhibiteurs de la metalloprotease matricielle
AU2003202093B2 (en) * 2001-07-02 2010-05-13 Aimsco Limited Treatment of MS with goat serum
JPWO2006016399A1 (ja) 2004-08-10 2008-05-01 株式会社静岡カフェイン工業所 ヒドロキサム酸誘導体及びそれを有効成分とする医薬
KR100844277B1 (ko) * 2005-04-29 2008-07-07 (주)아모레퍼시픽 히드록삼산 유도체 및 이의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743587A (en) * 1985-09-10 1988-05-10 G. D. Searle & Co. Hydroxamic acid based collagenase inhibitors
GB8827305D0 (en) * 1988-11-23 1988-12-29 British Bio Technology Compounds
GB9504084D0 (en) * 1995-03-01 1995-04-19 British Biotech Pharm Synthesis of carboxylic and hydroxamic acid derivatives

Also Published As

Publication number Publication date
GB9601041D0 (en) 1996-03-20
HUP9901022A3 (en) 2001-11-28
WO1997026257A1 (en) 1997-07-24
BR9707024A (pt) 1999-07-20
TW462967B (en) 2001-11-11
NO983283L (no) 1998-09-16
PL327820A1 (en) 1999-01-04
EP0912545A1 (en) 1999-05-06
AU725056B2 (en) 2000-10-05
NO983283D0 (no) 1998-07-16
AR005472A1 (es) 1999-06-23
CN1213368A (zh) 1999-04-07
CA2242913A1 (en) 1997-07-24
HUP9901022A2 (hu) 1999-07-28
NZ326352A (en) 2000-03-27
ZA97345B (en) 1998-07-16
AU1443697A (en) 1997-08-11
IL125381A0 (en) 1999-03-12
JP2000503312A (ja) 2000-03-21
CZ222498A3 (cs) 1999-03-17
KR19990077325A (ko) 1999-10-25

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