TNSN99159A1 - Forme polymorphe de monohydrate de zopolrestat, procedes pour sa preparation et compositions pharmaceutiques la contenant - Google Patents

Forme polymorphe de monohydrate de zopolrestat, procedes pour sa preparation et compositions pharmaceutiques la contenant

Info

Publication number
TNSN99159A1
TNSN99159A1 TNTNSN99159A TNSN99159A TNSN99159A1 TN SN99159 A1 TNSN99159 A1 TN SN99159A1 TN TNSN99159 A TNTNSN99159 A TN TNSN99159A TN SN99159 A TNSN99159 A TN SN99159A TN SN99159 A1 TNSN99159 A1 TN SN99159A1
Authority
TN
Tunisia
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
methods
same
Prior art date
Application number
TNTNSN99159A
Other languages
English (en)
Inventor
Francis Lambert John
Norris Timothy
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN99159A1 publication Critical patent/TNSN99159A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION CONCERNE LE MONOHYDRATE D'ACIDE 3,4 - DIHYDRO - 4 - OXO -3- ((5- TRIFLUOROMETHYL) - 2 - BENZOTHIAZOLYL ) - METHYL) -1- PHTALAZINEACETIQUE ET SES FORMES POLYMORPHES. ELLE CONCERNE EGALEMENT DES PROCEDES POUR LA PREPARATION ET DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSES ET COMPOSITIONS POUR LE TRAITEMENT DES COMPLICATIONS DIABETIQUES ET LA DIMINUTION DES TAUX SANGUINS DE LIPIDES OU D'ACIDE URIQUE.
TNTNSN99159A 1998-08-21 1999-08-18 Forme polymorphe de monohydrate de zopolrestat, procedes pour sa preparation et compositions pharmaceutiques la contenant TNSN99159A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9747498P 1998-08-21 1998-08-21

Publications (1)

Publication Number Publication Date
TNSN99159A1 true TNSN99159A1 (fr) 2005-11-10

Family

ID=22263562

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN99159A TNSN99159A1 (fr) 1998-08-21 1999-08-18 Forme polymorphe de monohydrate de zopolrestat, procedes pour sa preparation et compositions pharmaceutiques la contenant

Country Status (31)

Country Link
US (1) US6159976A (fr)
EP (1) EP0982306A3 (fr)
JP (1) JP2000072769A (fr)
KR (1) KR20000017411A (fr)
CN (1) CN1245804A (fr)
AP (1) AP9901662A0 (fr)
AU (1) AU4453299A (fr)
BG (1) BG103674A (fr)
BR (1) BR9903873A (fr)
CA (1) CA2280590A1 (fr)
EA (1) EA199900675A3 (fr)
EE (1) EE9900385A (fr)
GT (1) GT199900137A (fr)
HR (1) HRP990259A2 (fr)
HU (1) HUP9902783A3 (fr)
ID (1) ID23307A (fr)
IL (1) IL131419A0 (fr)
IS (1) IS5155A (fr)
MA (1) MA26678A1 (fr)
NO (1) NO994027L (fr)
NZ (1) NZ337363A (fr)
OA (1) OA11150A (fr)
PA (1) PA8480601A1 (fr)
PE (1) PE20000993A1 (fr)
PL (1) PL335016A1 (fr)
SG (1) SG83147A1 (fr)
TN (1) TNSN99159A1 (fr)
TR (1) TR199901996A2 (fr)
UY (1) UY25668A1 (fr)
YU (1) YU39899A (fr)
ZA (1) ZA995297B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5934206B2 (ja) 2010-07-16 2016-06-15 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク アルドース還元酵素阻害剤および同使用方法
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
US20140228319A1 (en) * 2013-02-13 2014-08-14 Banavara L. Mylari Water soluble salts of aldose reductase inhibitors for treatment of diabetic complications
ES2836500T3 (es) 2016-06-21 2021-06-25 Univ Columbia Inhibidores de aldosa reductasa y métodos de uso de los mismos
US11590131B2 (en) 2017-07-28 2023-02-28 Applied Therapeutics, Inc. Compositions and methods for treating galactosemia
SG11202110590PA (en) 2019-04-01 2021-10-28 Applied Therapeutics Inc Inhibitors of aldose reductase
WO2021202523A1 (fr) 2020-03-31 2021-10-07 Applied Therapeutics, Inc. Inhibiteurs d'aldose réductase pour le traitement du syndrome de détresse respiratoire aiguë, d'une inflammation/lésion pulmonaire aiguë, d'une lésion cardiaque et pour une thérapie antivirale
CN115996725A (zh) 2020-05-01 2023-04-21 应用治疗公司 用于治疗山梨糖醇脱氢酶缺乏症的醛糖还原酶抑制剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939140A (en) * 1985-11-07 1990-07-03 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
US4748280A (en) * 1985-11-07 1988-05-31 Pfizer Inc. Certain chlorination process for preparing 2-chloro-1,1,1-(C1 -C6)
JPH0676391B2 (ja) * 1987-06-09 1994-09-28 フアイザー・インコーポレイテツド ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法
US4868301A (en) * 1987-06-09 1989-09-19 Pfizer Inc. Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
US4904782A (en) * 1988-02-29 1990-02-27 Pfizer Inc. Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
WO1992003432A1 (fr) * 1990-08-28 1992-03-05 Pfizer Inc. Monohydrate d'acide 3-(5-trifluoromethylbenzothiazol-2-ylmethyle)-4-oxo-3h-phytalazine-1-ylacetique
US5391551A (en) * 1993-05-10 1995-02-21 Pfizer Inc. Method of lowering blood lipid levels
US6127367A (en) * 1996-02-29 2000-10-03 Pfizer, Inc. Method of reducing tissue damage associated with non-cardiac ischemia

Also Published As

Publication number Publication date
HUP9902783A2 (hu) 2000-12-28
CA2280590A1 (fr) 2000-02-21
PA8480601A1 (es) 2000-09-29
EP0982306A3 (fr) 2000-07-05
BR9903873A (pt) 2000-09-19
AU4453299A (en) 2000-03-09
EA199900675A2 (ru) 2000-02-28
OA11150A (en) 2003-04-16
EA199900675A3 (ru) 2000-06-26
TR199901996A2 (xx) 2000-03-21
AP9901662A0 (en) 1999-09-30
KR20000017411A (ko) 2000-03-25
YU39899A (sh) 2002-12-10
PE20000993A1 (es) 2000-10-04
IL131419A0 (en) 2001-01-28
ZA995297B (en) 2001-02-19
NO994027D0 (no) 1999-08-20
NO994027L (no) 2000-02-22
PL335016A1 (en) 2000-02-28
EE9900385A (et) 2000-04-17
UY25668A1 (es) 2001-08-27
MA26678A1 (fr) 2004-12-20
US6159976A (en) 2000-12-12
NZ337363A (en) 2001-01-26
CN1245804A (zh) 2000-03-01
GT199900137A (es) 2001-02-09
ID23307A (id) 2000-04-05
JP2000072769A (ja) 2000-03-07
BG103674A (en) 2000-03-31
IS5155A (is) 2000-02-22
HUP9902783A3 (en) 2001-01-29
SG83147A1 (en) 2001-09-18
EP0982306A2 (fr) 2000-03-01
HU9902783D0 (en) 1999-10-28
HRP990259A2 (en) 2000-06-30

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TNSN99159A1 (fr) Forme polymorphe de monohydrate de zopolrestat, procedes pour sa preparation et compositions pharmaceutiques la contenant