TH8922C3 - Preparation process of safflower extract containing hydroxysafer yellow A content. (hydroxysafflor yellow) high - Google Patents

Abstract

DC60 (January 31, 2013) The preparation method for a safflower extract with a high concentration of hydroxysafflor yellow A involves mixing dried safflower flowers with an organic solvent and water, followed by fermentation. The mixture is then filtered and centrifuged to extract the soluble portion. The soluble portion is then evaporated to remove the organic solvent, and the extract is dried again using a freeze dryer. This process yields a safflower extract in the form of a reddish-yellow powder. This method increases the extract yield and prevents loss of active compounds due to prolonged heat exposure. The resulting extract has a high concentration of hydroxysafflor yellow A, which exhibits hair growth-promoting activity in dermal papilla cells and increases hair density by enhancing melanocyte production. The process for extracting safflower (hydroxysafflor yellow A) involves mixing dried safflower flowers with an organic solvent and water, then fermenting the mixture. The mixture is then filtered and centrifuged to extract the soluble portion. The soluble portion is then evaporated to remove the organic solvent, and the mixture is dried again using a freeze dryer. This process yields a safflower extract in the form of a reddish-yellow powder. This method increases the yield of the extract and prevents loss of the active compounds due to prolonged heat exposure. The preparation method results in a high concentration of hydroxysafflor yellow A, an extract that exhibits hair growth-promoting activity in dermal papilla cells and increases hair density by enhancing melanocyte production.

Claims (1)

All claims which will not appear on the advertisement page: 1. The preparation method for safflower extract with a high concentration of hydroxysafflor yellow A involves the following steps: - Dried safflower flowers, baked at 45-50°C for 24-30 hours, are mixed with 50% ethanol as a solvent, in a ratio of 1 part dried safflower to 50% ethanol (1:20-25). - The mixture is then fermented in an opaque container for 3 days, stirring 2-3 times daily for 10-20 cycles each time. - After fermentation, the mixture is filtered, and the solution is extracted from the safflower flowers. - The filtered portion is centrifuged at 4,000 rpm for 10 minutes at 20-27°C, and the solution is collected. - Evaporate the solution using a rotary evaporator at 45-50 degrees Celsius until 60-70 percent of its weight is lost. Then add pure water, 1/5 the volume of the remaining solution, and continue evaporating for 10-15 minutes. - Further dry the resulting substance using a freeze dryer to obtain a safflower extract powder with a reddish-yellow color.