SU1388773A1 - Method of determining carbocromene in preparation of aqueous solution - Google Patents

Method of determining carbocromene in preparation of aqueous solution Download PDF

Info

Publication number
SU1388773A1
SU1388773A1 SU853899322A SU3899322A SU1388773A1 SU 1388773 A1 SU1388773 A1 SU 1388773A1 SU 853899322 A SU853899322 A SU 853899322A SU 3899322 A SU3899322 A SU 3899322A SU 1388773 A1 SU1388773 A1 SU 1388773A1
Authority
SU
USSR - Soviet Union
Prior art keywords
aqueous solution
preparation
determining
carbocromene
carbocromen
Prior art date
Application number
SU853899322A
Other languages
Russian (ru)
Inventor
Анатолий Алексеевич Хабаров
Олег Анатольевич Григорьев
Людмила Пантелеймоновна Хабарова
Николай Ильич Громнацкий
Семен Иосифович Вайстух
Original Assignee
Курский Государственный Медицинский Институт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Курский Государственный Медицинский Институт filed Critical Курский Государственный Медицинский Институт
Priority to SU853899322A priority Critical patent/SU1388773A1/en
Application granted granted Critical
Publication of SU1388773A1 publication Critical patent/SU1388773A1/en

Links

Landscapes

  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

Изобретение относитс  к химико- фармацевтической промьшшенностио Дл  повышени  чувствительности способа водный раствор карбокромена обраба- тьшают концентрированной серной кислотой с последующим измерением интенсивности флюоресценции раствора при длине волны возбуждени  300- 380 нм и излучени  370-460 нм Чувствительность способа 0,001 Ji млоThe invention relates to pharmaceutical and pharmaceutical industry. To increase the sensitivity of the method, an aqueous solution of carbocromen is treated with concentrated sulfuric acid, followed by measuring the fluorescence intensity of the solution at an excitation wavelength of 300-380 nm and radiation of 370-460 nm

Description

со 00from 00

0000

соwith

113113

Изобретение относитс  к фармацевтическому анализу, в частности к способ лм определени  карбокроменасThe invention relates to pharmaceutical analysis, in particular, to the method of determination of carbochromenas

Цель изобретени  - повышение чувствительности СПОСОбЗоThe purpose of the invention is to increase the sensitivity of the method.

Пример 1 о Точнзпо навеску порошка мелкоизмельченных таблеток карбокромена помещают в мерную колбу на 100 мл, прибавл ют 50 мл ди- стиллированной Воды, встр хивают 3-5 мин и довод т до метки. К 0,5 мл данного раствора (аликвотна  часть) прибавл ют 9,5 мл , (концентрированной ), перемешивают и измер ют флюоресценцию по отношению к стандартному раствору, содержащему 10 мкг/мл карбокромена в концентрированной HgSO, при / возбуждени  359 нм и 7 излучени  415 нмо КонExample 1 A sample of powdered carbocromen tablets is placed in a 100 ml volumetric flask, 50 ml of distilled Water is added, shaken for 3-5 minutes and brought to the mark. 9.5 ml (concentrated) is added to 0.5 ml of this solution (aliquot part), mixed and the fluorescence is measured relative to a standard solution containing 10 µg / ml of carbocromen in concentrated HgSO4 at 359 nm excitation and 7 415 nm radiation Cohn

Результаты флюориметрического определени  карбокромена в таблетках по 0,075 гResults of fluorometric determination of carbocromen tablets 0,075 g

центрацию карбокромена определ ют по калибровочному графику, Результаты определени  карбокромена в таблетках по 0,075 представлены в таблицеthe concentration of the carbocromen is determined by the calibration graph. The results of the determination of the carbocromen in tablets of 0.075 are presented in the table.

Чувствительность способа составл ет 0,001 /мПоThe sensitivity of the method is 0.001 / mPo.

Claims (1)

Формула изобретени Invention Formula Способ определени  карбокромена в водном растворе препарата, отличающийс  тем, что, с целью повьшени  чувствительностиThe method for determining carbocromen in an aqueous solution of a preparation, characterized in that, in order to increase the sensitivity способа, анализируемую пробу обрабатывают концентрированной серной кислотой с последующим измерением интенсивности флюоресценции рас тво- ра при длине волны возбуждени  300 380 нм и излучени  370-460 имmethod, the analyzed sample is treated with concentrated sulfuric acid, followed by measuring the fluorescence intensity of the solution at an excitation wavelength of 300 380 nm and radiation of 370-460 them
SU853899322A 1985-05-20 1985-05-20 Method of determining carbocromene in preparation of aqueous solution SU1388773A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU853899322A SU1388773A1 (en) 1985-05-20 1985-05-20 Method of determining carbocromene in preparation of aqueous solution

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU853899322A SU1388773A1 (en) 1985-05-20 1985-05-20 Method of determining carbocromene in preparation of aqueous solution

Publications (1)

Publication Number Publication Date
SU1388773A1 true SU1388773A1 (en) 1988-04-15

Family

ID=21178631

Family Applications (1)

Application Number Title Priority Date Filing Date
SU853899322A SU1388773A1 (en) 1985-05-20 1985-05-20 Method of determining carbocromene in preparation of aqueous solution

Country Status (1)

Country Link
SU (1) SU1388773A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Временна фармакопейна стать № 42-339-74 *

Similar Documents

Publication Publication Date Title
McNeil et al. Fluorometric estimation of GSH-OPT
SU1388773A1 (en) Method of determining carbocromene in preparation of aqueous solution
SU1605189A1 (en) Method of determining iron (ii) and iron (iii) in case of joint presence thereof
SU1182347A1 (en) Method of determining quinine iodobismuthate
SU1583803A1 (en) Method of determining quinone in iodo-bismuth quinine
SU1120240A1 (en) Method of identifying carbamazepine
SU957075A1 (en) Hydrochloride salsoline determination method
SU857805A1 (en) Method of quantitative determination of 1-tetrahydroparamitin alcaloid hydrochloride
SU1684638A1 (en) Method of quantitative determination of polyethylene polyamine
Pavon et al. Simultaneous determination of gallium and aluminium in biological samples by conventional luminescence and derivative synchronous fluorescence spectrometry
SU1599727A1 (en) Method of qualitative determination of polyvinylpyrrolidone
SU717631A1 (en) Method of quantitative determining of sodium para-aminosalicylate
SU1617333A1 (en) Method of determining derivatives of amide sulphanilic acid
SU1409885A1 (en) Method of determining fluorine
Dent et al. Sodium Coumarin 6-Sulfonate, A Fluorometric Ion-Pairing Reagent for Tertiary Amines. Application to the Determination of Chlorpheniramine Maleate
SU1578603A1 (en) Method of quantitative determination of benzyl penicilline in sample
SU1280504A1 (en) Method of quantitative determination of etherin salicylate
SU1065779A1 (en) Method of determination of folium acid in feeds
SU1337739A1 (en) Method of determining amitryptelene in medicinal compounds
SU1415159A1 (en) Method of quantitative determination of novocaine
SU1589152A1 (en) Method of determining cronolactone
SU1165995A1 (en) Method of determining 1,8 anthraquinone dioxide
SU1323924A1 (en) Method of identifying 2-methyl-4,6-dinitrophenol in air
SU1255950A1 (en) Method of determining n-beta-phenoxyethyl-n,n-dimethyl-h-(2-oxy-3-acetyl-5-chlorobenzyl)-ammonium
SU1141318A1 (en) Method of photometric determination of water-soluble lignin derivative content