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FIELD: medicine, colloidal chemistry. SUBSTANCE: copolymer of polyhydroxyethylene-polyhydroxypropylene (proxanol) is dissolved in water and egg yolk phospholipids and a mixture of perfluorodecaline and perfluoro-para-methylcyclopyridine taken at ratio 1:3 were added to solution. Mixture is stirred in turbine mixer at 4000-8000 rev/min for 1-2 min. Obtained parental coarse dispersed emulsion is passed many times (10-12 times) through hydroextrusion device under pressure 60-300 MPa at 1-20 C. Obtained emulsion shows average particle size is 0.157 mcm and diameter 0.05-0.34 mcm. Fluoride ion content in emulsion is 2.3 x 10M. Emulsion is used as blood substituent. Fraction of particle in emulsion at size above 0.2 mcm is decreased. EFFECT: lowered toxicity of emulsion. 1 tbl
SU3788371/14A1984-09-051984-09-05Method of perfluorocarbon emulsion preparing
SU1298976A1
(en)