SMT202200449T1 - Sistemi per la somministrazione di farmaci e metodi per il trattamento del cancro della vescica con gemcitabina - Google Patents
Sistemi per la somministrazione di farmaci e metodi per il trattamento del cancro della vescica con gemcitabinaInfo
- Publication number
- SMT202200449T1 SMT202200449T1 SM20220449T SMT202200449T SMT202200449T1 SM T202200449 T1 SMT202200449 T1 SM T202200449T1 SM 20220449 T SM20220449 T SM 20220449T SM T202200449 T SMT202200449 T SM T202200449T SM T202200449 T1 SMT202200449 T1 SM T202200449T1
- Authority
- SM
- San Marino
- Prior art keywords
- gemcitabine
- treatment
- methods
- drug delivery
- delivery systems
- Prior art date
Links
- 206010005003 Bladder cancer Diseases 0.000 title 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 title 1
- 229960005277 gemcitabine Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 201000005112 urinary bladder cancer Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Nanotechnology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461949215P | 2014-03-06 | 2014-03-06 | |
| EP15711373.9A EP3113782B1 (en) | 2014-03-06 | 2015-03-06 | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
| PCT/US2015/019262 WO2015134911A1 (en) | 2014-03-06 | 2015-03-06 | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT202200449T1 true SMT202200449T1 (it) | 2023-01-13 |
Family
ID=52697553
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20220449T SMT202200449T1 (it) | 2014-03-06 | 2015-03-06 | Sistemi per la somministrazione di farmaci e metodi per il trattamento del cancro della vescica con gemcitabina |
| SM20250385T SMT202500385T1 (it) | 2014-03-06 | 2015-03-06 | Sistemi e metodi di erogazione di farmaco per il trattamento del cancro della vescica con gemcitabina |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20250385T SMT202500385T1 (it) | 2014-03-06 | 2015-03-06 | Sistemi e metodi di erogazione di farmaco per il trattamento del cancro della vescica con gemcitabina |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20150250717A1 (https=) |
| EP (2) | EP4124339B1 (https=) |
| JP (5) | JP6901858B2 (https=) |
| KR (1) | KR102338079B1 (https=) |
| CN (2) | CN106102751A (https=) |
| AU (4) | AU2015226901B2 (https=) |
| BR (1) | BR112016020381A8 (https=) |
| CA (1) | CA2939979C (https=) |
| DK (2) | DK4124339T3 (https=) |
| ES (2) | ES2930435T3 (https=) |
| FI (1) | FI4124339T3 (https=) |
| HR (2) | HRP20251264T1 (https=) |
| HU (1) | HUE060704T2 (https=) |
| IL (2) | IL247347B2 (https=) |
| LT (2) | LT4124339T (https=) |
| MX (1) | MX2016011333A (https=) |
| PL (2) | PL3113782T3 (https=) |
| PT (2) | PT3113782T (https=) |
| RS (2) | RS67337B1 (https=) |
| RU (1) | RU2694902C1 (https=) |
| SG (2) | SG11201607342QA (https=) |
| SI (1) | SI4124339T1 (https=) |
| SM (2) | SMT202200449T1 (https=) |
| WO (1) | WO2015134911A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX367070B (es) | 2012-08-31 | 2019-08-05 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la prostata. |
| KR102385603B1 (ko) | 2013-08-19 | 2022-04-11 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
| LT4124339T (lt) * | 2014-03-06 | 2025-11-10 | Vaisto įvedimo sistemos ir būdai šlapimo pūslės vėžiui gydyti gemcitabinu | |
| CN118453872A (zh) * | 2016-05-06 | 2024-08-09 | 塔里斯生物医药公司 | 治疗下尿路尿道上皮癌的方法 |
| BR112020000832A2 (pt) * | 2017-07-25 | 2020-07-21 | Taris Biomedical Llc | métodos para tratar metástase tumoral |
| JOP20200124A1 (ar) * | 2017-11-08 | 2020-05-20 | Taris Biomedical Llc | طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
| EP4039279A4 (en) * | 2019-10-03 | 2023-11-01 | Seikagaku Corporation | TRANSMUCOSAL MEDICINAL ACTIVE DELIVERY SYSTEM FOR THE BLADDER SUBMUCOSA |
| RU2713443C2 (ru) * | 2019-11-01 | 2020-02-05 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) | Способ комбинированного лечения мышечно-инвазивного рака мочевого пузыря т3-т4 n0-+m0 |
| US20230073301A1 (en) * | 2020-01-27 | 2023-03-09 | Isola Therapeutics, Inc. | Tissue dosing for intraluminal local drug delivery |
| CN112169066B (zh) * | 2020-10-29 | 2023-05-12 | 安徽省立医院(中国科学技术大学附属第一医院) | 具有控制器的连续缓释给药留置管 |
| CN113616666A (zh) * | 2021-08-24 | 2021-11-09 | 傅广波 | 膀胱黏膜下注射吉西他滨在治疗膀胱癌中的应用 |
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| EP1372602B1 (en) | 2001-01-09 | 2007-04-18 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
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| CA2503193A1 (en) | 2002-10-22 | 2004-05-06 | The Biomerix Corporation | Method and system for intravesicular delivery of therapeutic agents |
| ATE387236T1 (de) * | 2003-03-31 | 2008-03-15 | Alza Corp | Osmotische pumpe mit mitteln zum ableiten des innendrucks |
| US8361490B2 (en) | 2004-09-16 | 2013-01-29 | Theracoat Ltd. | Biocompatible drug delivery apparatus and methods |
| DK1933810T3 (da) | 2005-08-11 | 2013-01-28 | Childrens Medical Center | Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde |
| WO2007145704A2 (en) * | 2006-04-24 | 2007-12-21 | Gloucester Pharmaceuticals | Gemcitabine combination therapy |
| EP1913962A1 (en) | 2006-10-22 | 2008-04-23 | Ophir Perelson | Expandable medical device for the treatment and prevention of cardiovascular diseases |
| KR101538748B1 (ko) | 2007-12-11 | 2015-07-22 | 메사추세츠 인스티튜트 오브 테크놀로지 | 이식형 의약 투여 장치와 방광과 기타 신체 낭 또는 내강의 치료 방법 |
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| DK2445570T3 (da) | 2009-06-26 | 2013-02-25 | Taris Biomedical Inc | Implanterbare lægemiddelafgivelsesindretninger samt fremgangsmåder til deres fremstilling |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| PL3884988T3 (pl) | 2009-12-17 | 2025-09-08 | Taris Biomedical Llc | Urządzenie implantowalne z tolerancją wewnątrzpęcherzową |
| ES2732150T3 (es) * | 2010-01-20 | 2019-11-20 | Urogen Pharma Ltd | Material y método para tratar cavidades internas |
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| WO2011153009A1 (en) | 2010-06-02 | 2011-12-08 | Abraxis Bioscience, Llc | Methods of treating bladder cancer |
| EP3795121A1 (en) | 2010-08-05 | 2021-03-24 | TARIS Biomedical LLC | Ureteral stent drug delivery device |
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| CN104470535A (zh) | 2012-03-29 | 2015-03-25 | 阿尔托生物科学有限公司 | 用于治疗肿瘤的方法 |
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| MX367070B (es) * | 2012-08-31 | 2019-08-05 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la prostata. |
| SG11201501424SA (en) | 2012-08-31 | 2015-03-30 | Taris Biomedical Llc | Drug delivery systems and methods for treatment of bladder cancer comprising oxaliplatin |
| MX379066B (es) | 2012-09-18 | 2025-03-04 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la disfuncion miccional de la vejiga y otros trastornos del tracto urinario inferior. |
| JP2016508842A (ja) | 2013-03-05 | 2016-03-24 | タリス バイオメディカル エルエルシー | 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法 |
| EP2968120B1 (en) | 2013-03-15 | 2026-01-14 | TARIS Biomedical LLC | Drug delivery devices and methods for drug delivery |
| KR102557326B1 (ko) * | 2013-03-15 | 2023-07-19 | 타리스 바이오메디컬 엘엘씨 | 약물-투과성 구성요소를 가지는 약물 전달 장치 |
| CA2944480C (en) | 2013-04-10 | 2021-05-18 | Massachusetts Institute Of Technology | Local drug delivery devices and methods for treating cancer |
| KR102385603B1 (ko) * | 2013-08-19 | 2022-04-11 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
| EP3065807A1 (en) * | 2013-11-05 | 2016-09-14 | TARIS Biomedical LLC | Osmotic drug delivery devices, kits, and methods |
| LT4124339T (lt) | 2014-03-06 | 2025-11-10 | Vaisto įvedimo sistemos ir būdai šlapimo pūslės vėžiui gydyti gemcitabinu | |
| RU2591946C2 (ru) | 2014-06-24 | 2016-07-20 | Владимир Эдуардович Анников | Способ изготовления гелеобразного водосодержащего взрывчатого состава |
| KR20220061253A (ko) | 2014-06-26 | 2022-05-12 | 타리스 바이오메디컬 엘엘씨 | 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 |
| WO2016172704A1 (en) | 2015-04-23 | 2016-10-27 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
| CN118453872A (zh) | 2016-05-06 | 2024-08-09 | 塔里斯生物医药公司 | 治疗下尿路尿道上皮癌的方法 |
| BR112020000832A2 (pt) | 2017-07-25 | 2020-07-21 | Taris Biomedical Llc | métodos para tratar metástase tumoral |
| JOP20200124A1 (ar) | 2017-11-08 | 2020-05-20 | Taris Biomedical Llc | طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
-
2015
- 2015-03-06 LT LTEP22196596.5T patent/LT4124339T/lt unknown
- 2015-03-06 ES ES15711373T patent/ES2930435T3/es active Active
- 2015-03-06 SG SG11201607342QA patent/SG11201607342QA/en unknown
- 2015-03-06 JP JP2016555554A patent/JP6901858B2/ja active Active
- 2015-03-06 SM SM20220449T patent/SMT202200449T1/it unknown
- 2015-03-06 DK DK22196596.5T patent/DK4124339T3/da active
- 2015-03-06 ES ES22196596T patent/ES3051417T3/es active Active
- 2015-03-06 CN CN201580011259.9A patent/CN106102751A/zh active Pending
- 2015-03-06 CA CA2939979A patent/CA2939979C/en active Active
- 2015-03-06 SM SM20250385T patent/SMT202500385T1/it unknown
- 2015-03-06 RS RS20251017A patent/RS67337B1/sr unknown
- 2015-03-06 HR HRP20251264TT patent/HRP20251264T1/hr unknown
- 2015-03-06 IL IL247347A patent/IL247347B2/en unknown
- 2015-03-06 HU HUE15711373A patent/HUE060704T2/hu unknown
- 2015-03-06 WO PCT/US2015/019262 patent/WO2015134911A1/en not_active Ceased
- 2015-03-06 PT PT157113739T patent/PT3113782T/pt unknown
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