SMT201500069B - Composizioni farmaceutiche comprendenti n-(4-(2-ammino-3-cloropiridin-4-ilossi)-3-fluorofenil)-4-etossi-l-(4-fluorofenil)-2-osso-1,2-diidropiridin-3-carbossammide - Google Patents
Composizioni farmaceutiche comprendenti n-(4-(2-ammino-3-cloropiridin-4-ilossi)-3-fluorofenil)-4-etossi-l-(4-fluorofenil)-2-osso-1,2-diidropiridin-3-carbossammideInfo
- Publication number
- SMT201500069B SMT201500069B SM201500069T SM201500069T SMT201500069B SM T201500069 B SMT201500069 B SM T201500069B SM 201500069 T SM201500069 T SM 201500069T SM 201500069 T SM201500069 T SM 201500069T SM T201500069 B SMT201500069 B SM T201500069B
- Authority
- SM
- San Marino
- Prior art keywords
- fluorophenyl
- carbossammide
- dihydropyridin
- chloropyridin
- yloxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32971010P | 2010-04-30 | 2010-04-30 | |
| PCT/US2011/034417 WO2011137274A1 (en) | 2010-04-30 | 2011-04-29 | Pharmaceutical compositions comprising n-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-l-(4-fluorophenyl)-2-oxo- 1,2-dihydropyridine-3 -carboxamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201500069B true SMT201500069B (it) | 2015-05-05 |
Family
ID=44209564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201500069T SMT201500069B (it) | 2010-04-30 | 2015-03-18 | Composizioni farmaceutiche comprendenti n-(4-(2-ammino-3-cloropiridin-4-ilossi)-3-fluorofenil)-4-etossi-l-(4-fluorofenil)-2-osso-1,2-diidropiridin-3-carbossammide |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8911785B2 (ja) |
| EP (1) | EP2563763B1 (ja) |
| JP (1) | JP5820874B2 (ja) |
| KR (1) | KR101897302B1 (ja) |
| CN (1) | CN102971296B (ja) |
| DK (1) | DK2563763T3 (ja) |
| ES (1) | ES2533075T3 (ja) |
| HK (1) | HK1179260A1 (ja) |
| HR (1) | HRP20150105T1 (ja) |
| MY (1) | MY183769A (ja) |
| PL (1) | PL2563763T3 (ja) |
| PT (1) | PT2563763E (ja) |
| RS (1) | RS53790B1 (ja) |
| SG (1) | SG184891A1 (ja) |
| SI (1) | SI2563763T1 (ja) |
| SM (1) | SMT201500069B (ja) |
| WO (1) | WO2011137274A1 (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013096858A1 (en) * | 2011-12-22 | 2013-06-27 | Life Technologies Corporation | Cell culture media and methods |
| KR101545268B1 (ko) | 2015-02-05 | 2015-08-20 | 보령제약 주식회사 | 정제 및 이의 제조방법 |
| WO2016126012A1 (en) * | 2015-02-05 | 2016-08-11 | Boryung Pharmaceutical Co., Ltd | Tablet and method of preparing the same |
| US20220119425A1 (en) * | 2019-01-15 | 2022-04-21 | The Translational Genomics Research Institute | Phosphonate conjugates and uses thereof |
| US20230257364A1 (en) * | 2022-02-16 | 2023-08-17 | Cmg Pharmaceutical Co., Ltd. | Pyridazinone-based compounds as axl, c-met, and mer inhibitors and methods of use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214344B1 (en) | 1995-06-02 | 2001-04-10 | Genetech, Inc. | Hepatocyte growth factor receptor antagonists and uses thereof |
| ID21762A (id) * | 1996-09-24 | 1999-07-22 | Lilly Co Eli | Formulasi partikel bersaput |
| US7459562B2 (en) | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
| WO2006118210A1 (ja) * | 2005-04-28 | 2006-11-09 | Eisai R & D Management Co., Ltd. | ジヒドロピリジン系化合物の分解を防止する方法 |
| TR200504775A1 (tr) | 2005-11-30 | 2007-10-22 | Esen Beki̇r | Kendinden metal takviyeli pvc pencere ve kapı profilleri |
| PL1808164T3 (pl) * | 2006-01-05 | 2009-06-30 | Teva Pharma | Sposób z granulacją na mokro do wytwarzania kompozycji farmaceutycznych aripiprazolu |
| CN101535264B (zh) * | 2006-11-08 | 2012-11-28 | 百时美施贵宝公司 | 吡啶酮化合物 |
| US20080260837A1 (en) * | 2007-04-20 | 2008-10-23 | Qpharma, L.L.C. | Physically stable aqueous suspensions of active pharmaceuticals |
| US8263652B2 (en) * | 2007-10-31 | 2012-09-11 | Sk Biopharmaceuticals Co., Ltd. | Stabilized pediatric suspension of carisbamate |
| JP5693239B2 (ja) | 2008-01-23 | 2015-04-01 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ４−ピリジノン化合物および癌についてのその使用 |
-
2011
- 2011-04-29 EP EP11717917.6A patent/EP2563763B1/en active Active
- 2011-04-29 WO PCT/US2011/034417 patent/WO2011137274A1/en active Application Filing
- 2011-04-29 PT PT11717917T patent/PT2563763E/pt unknown
- 2011-04-29 CN CN201180032341.1A patent/CN102971296B/zh active Active
- 2011-04-29 JP JP2013508267A patent/JP5820874B2/ja active Active
- 2011-04-29 RS RS20150055A patent/RS53790B1/en unknown
- 2011-04-29 PL PL11717917T patent/PL2563763T3/pl unknown
- 2011-04-29 US US13/643,561 patent/US8911785B2/en active Active
- 2011-04-29 SG SG2012076865A patent/SG184891A1/en unknown
- 2011-04-29 KR KR1020127031220A patent/KR101897302B1/ko active IP Right Grant
- 2011-04-29 SI SI201130405T patent/SI2563763T1/sl unknown
- 2011-04-29 DK DK11717917.6T patent/DK2563763T3/en active
- 2011-04-29 ES ES11717917.6T patent/ES2533075T3/es active Active
- 2011-04-29 MY MYPI2012004708A patent/MY183769A/en unknown
-
2013
- 2013-06-10 HK HK13106831.5A patent/HK1179260A1/xx unknown
-
2014
- 2014-09-15 US US14/486,139 patent/US9233948B2/en active Active
-
2015
- 2015-01-28 HR HRP20150105AT patent/HRP20150105T1/hr unknown
- 2015-03-18 SM SM201500069T patent/SMT201500069B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8911785B2 (en) | 2014-12-16 |
| KR20130100237A (ko) | 2013-09-10 |
| EP2563763B1 (en) | 2014-12-31 |
| EP2563763A1 (en) | 2013-03-06 |
| DK2563763T3 (en) | 2015-04-07 |
| HRP20150105T1 (hr) | 2015-03-13 |
| CN102971296B (zh) | 2015-11-25 |
| US20150065719A1 (en) | 2015-03-05 |
| MY183769A (en) | 2021-03-12 |
| ES2533075T3 (es) | 2015-04-07 |
| PT2563763E (pt) | 2015-03-31 |
| PL2563763T3 (pl) | 2015-06-30 |
| US9233948B2 (en) | 2016-01-12 |
| WO2011137274A1 (en) | 2011-11-03 |
| SI2563763T1 (sl) | 2015-03-31 |
| US20130039989A1 (en) | 2013-02-14 |
| HK1179260A1 (en) | 2013-09-27 |
| JP2013525455A (ja) | 2013-06-20 |
| RS53790B1 (en) | 2015-06-30 |
| AU2011245269A1 (en) | 2012-12-20 |
| SG184891A1 (en) | 2012-11-29 |
| CN102971296A (zh) | 2013-03-13 |
| KR101897302B1 (ko) | 2018-09-11 |
| JP5820874B2 (ja) | 2015-11-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SMT201700008B (it) | Composizione farmaceutica | |
| SMT201600350B (it) | Composizioni farmaceutiche | |
| BR112015002738A2 (pt) | composto , e , composição farmacêutica | |
| DK3284467T3 (da) | Nikotinholdige farmaceutiske sammensætninger | |
| BR112013024267A2 (pt) | compostos tricíclicos fundidos substituídos, composições e aplicações medicinais dos mesmos. | |
| IL222878A (en) | N - ((2-oxo-2,1-dihydropyridine-3-ram) methyl) -1h-indole-4-carboxamide and pharmaceuticals containing them | |
| BR112015003259A2 (pt) | composto, composição farmacêutica, e, composição de vacina. | |
| DK2632493T3 (da) | Lægemiddelindgivelsessammensætninger | |
| DK3246018T3 (da) | Farmaceutisk sammensætning | |
| BR112014003052A2 (pt) | composições farmacêuticas | |
| CO6930367A2 (es) | Composiciones farmaceúticas | |
| GT201200303A (es) | Formulaciones farmacéuticas | |
| EE201300005A (et) | Ravimkoostis | |
| BR112014009889A2 (pt) | compostos dissubstituídos, compostos e composição farmacêutica | |
| BR112014009950A2 (pt) | composto dissubstituído, compostos e composição farmacêutica | |
| BR112013019327A2 (pt) | composto, e, composição. | |
| BR112012000831A2 (pt) | compostos, composições farmacêuticas e métodos relacionados | |
| DK2938194T3 (da) | N-(substituerede)-5-fluor-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidin-1 (2h)-carboxylatderivater | |
| CO6801722A2 (es) | Composiciones farmacéuticas | |
| SMT201500069B (it) | Composizioni farmaceutiche comprendenti n-(4-(2-ammino-3-cloropiridin-4-ilossi)-3-fluorofenil)-4-etossi-l-(4-fluorofenil)-2-osso-1,2-diidropiridin-3-carbossammide | |
| CL2014002034A1 (es) | Compuestos derivados de isoxazol-fenil-azetidina fenil sustituidos; y compuestos intermediarios. | |
| IT1397694B1 (it) | Puntale per attacchi da sci-alpinismo. | |
| BR112014028443A2 (pt) | composição estéril. | |
| BR112013007469A2 (pt) | composições farmacêuticas antidiabéticas sólidas | |
| BR112012029461A2 (pt) | composição farmacêutica contendo solifenacina |