SMT201400029B - Terapia di disturbi neurologici a base di baclofene e acamprosato - Google Patents

Terapia di disturbi neurologici a base di baclofene e acamprosato

Info

Publication number
SMT201400029B
SMT201400029B SM201400029T SM201400029T SMT201400029B SM T201400029 B SMT201400029 B SM T201400029B SM 201400029 T SM201400029 T SM 201400029T SM 201400029 T SM201400029 T SM 201400029T SM T201400029 B SMT201400029 B SM T201400029B
Authority
SM
San Marino
Prior art keywords
acamprosate
baclofen
treatment
neurological disorders
disorders based
Prior art date
Application number
SM201400029T
Other languages
English (en)
Italian (it)
Inventor
Daniel Cohen
Lliya Chumakov
Serguei Nabirochkin
Emmanuel Vial
Mickael Guedj
Original Assignee
Pharnext
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharnext filed Critical Pharnext
Publication of SMT201400029B publication Critical patent/SMT201400029B/xx

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
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    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/445Non condensed piperidines, e.g. piperocaine
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61K9/0012Galenical forms characterised by the site of application
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    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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SM201400029T 2011-03-01 2014-03-12 Terapia di disturbi neurologici a base di baclofene e acamprosato SMT201400029B (it)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP11305217 2011-03-01
US201161468658P 2011-03-29 2011-03-29
US201161493606P 2011-06-06 2011-06-06
EP11305687 2011-06-06
EP12708113.1A EP2560631B1 (fr) 2011-03-01 2012-03-01 Thérapie de troubles neurologiques à base de baclofène et d'acamprosate
PCT/EP2012/053570 WO2012117076A2 (fr) 2011-03-01 2012-03-01 Thérapie de troubles neurologiques à base de baclofène et d'acamprosate

Publications (1)

Publication Number Publication Date
SMT201400029B true SMT201400029B (it) 2014-07-07

Family

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Family Applications (1)

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SM201400029T SMT201400029B (it) 2011-03-01 2014-03-12 Terapia di disturbi neurologici a base di baclofene e acamprosato

Country Status (27)

Country Link
US (7) US9820978B2 (fr)
EP (5) EP2680835B1 (fr)
JP (2) JP5987008B2 (fr)
KR (2) KR101937782B1 (fr)
CN (2) CN105997969B (fr)
AU (2) AU2012222351B2 (fr)
BR (1) BR112013022112B1 (fr)
CA (1) CA2828765C (fr)
CY (3) CY1115074T1 (fr)
DK (3) DK2796132T3 (fr)
EA (2) EA023277B1 (fr)
ES (5) ES2665569T3 (fr)
HK (2) HK1182615A1 (fr)
HR (1) HRP20140131T1 (fr)
HU (1) HUE038653T2 (fr)
IL (2) IL228177B (fr)
LT (2) LT2727588T (fr)
MX (1) MX340568B (fr)
PL (3) PL2796132T3 (fr)
PT (1) PT2560631E (fr)
RS (3) RS58114B1 (fr)
SG (2) SG192968A1 (fr)
SI (3) SI2727588T1 (fr)
SM (1) SMT201400029B (fr)
TR (1) TR201809351T4 (fr)
WO (2) WO2012117076A2 (fr)
ZA (1) ZA201306039B (fr)

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CN105658238B (zh) * 2013-06-19 2019-07-12 索姆创新生物技术公司 用于在预防和/或治疗多动性运动障碍中使用的治疗剂
KR102206745B1 (ko) * 2013-07-12 2021-02-03 경상대학교산학협력단 안토시아닌 및 gabab 수용체 작용제를 유효성분으로 포함하는 신경질환 치료제
WO2015023830A1 (fr) 2013-08-14 2015-02-19 Stc.Unm Traitement et prévention d'un accident vasculaire cérébral et d'autres troubles neurologiques
EP3062782A1 (fr) * 2013-10-30 2016-09-07 Pharnext Compositions, procédés et utilisations pour le traitements de diabète et d'états associés en régulant le niveau de glycémie
JP6619744B2 (ja) * 2014-02-11 2019-12-11 ファーネクストPharnext 神経障害の処置のためのバクロフェン、アカンプロセート、及び中鎖トリグリセライドの併用
KR102580378B1 (ko) * 2014-11-21 2023-09-19 바이오하벤 파마슈티컬 홀딩 컴퍼니 엘티디. 릴루졸의 설하 제제
EP3291800A4 (fr) 2015-05-04 2018-09-26 Confluence Pharmaceuticals, LLC Formulations d'acamprosate à pulvériser
EP3156050A1 (fr) * 2015-10-16 2017-04-19 Universitat Autònoma De Barcelona Nouvelles thérapies combinées pour le traitement de lésions neurologiques
WO2017115873A1 (fr) 2015-12-29 2017-07-06 国立大学法人京都大学 Agent pour la prévention et/ou le traitement de la maladie d'alzheimer
AU2017216288B2 (en) * 2016-02-05 2022-06-02 Pharnext Novel combinatorial therapies of neurological disorders
US10383870B2 (en) 2016-06-10 2019-08-20 Pharnext Early treatment of CMT disease
AU2018258970B2 (en) * 2017-04-24 2021-07-15 Pharnext Idalopirdine-based combinatorial therapies of Alzheimer's disease
WO2018213589A1 (fr) * 2017-05-17 2018-11-22 Confluence Pharmaceuticals, Llc Formulations d'homotaurines et de leurs sels
US11878001B2 (en) 2017-07-31 2024-01-23 Novartis Ag Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use
WO2019145523A1 (fr) 2018-01-29 2019-08-01 Pharnext Thérapie de la maladie d'alzheimer à base de baclofène et d'acamprosate chez des patients ayant perdu la sensibilité à une thérapie par un inhibiteur de l'acétylcholinestérase
CN112791078B (zh) 2019-11-13 2022-12-06 润佳(苏州)医药科技有限公司 同位素富集的3-氨基-1-丙磺酸及其衍生物的用途
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US20130090307A1 (en) 2013-04-11
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US20140378440A1 (en) 2014-12-25
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