SK75794A3 - Arylindole derivatives - Google Patents
Arylindole derivatives Download PDFInfo
- Publication number
- SK75794A3 SK75794A3 SK757-94A SK75794A SK75794A3 SK 75794 A3 SK75794 A3 SK 75794A3 SK 75794 A SK75794 A SK 75794A SK 75794 A3 SK75794 A3 SK 75794A3
- Authority
- SK
- Slovakia
- Prior art keywords
- alkyl
- hydrogen
- substituted
- alkenyl
- hydroxy groups
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 20
- 239000001257 hydrogen Substances 0.000 claims abstract description 19
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 19
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 16
- 150000002431 hydrogen Chemical class 0.000 claims abstract description 12
- 238000011282 treatment Methods 0.000 claims abstract description 11
- 208000028017 Psychotic disease Diseases 0.000 claims abstract description 10
- 229910052799 carbon Chemical group 0.000 claims abstract description 9
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- 125000000753 cycloalkyl group Chemical group 0.000 claims abstract description 8
- 125000004981 cycloalkylmethyl group Chemical group 0.000 claims abstract description 8
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- 125000001424 substituent group Chemical group 0.000 claims abstract description 8
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- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims abstract description 7
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 6
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- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 6
- 229910052717 sulfur Chemical group 0.000 claims abstract description 6
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- 230000000862 serotonergic effect Effects 0.000 description 1
- 229940076279 serotonin Drugs 0.000 description 1
- GZKLJWGUPQBVJQ-UHFFFAOYSA-N sertindole Chemical compound C1=CC(F)=CC=C1N1C2=CC=C(Cl)C=C2C(C2CCN(CCN3C(NCC3)=O)CC2)=C1 GZKLJWGUPQBVJQ-UHFFFAOYSA-N 0.000 description 1
- 229960000652 sertindole Drugs 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 230000007958 sleep Effects 0.000 description 1
- 208000019116 sleep disease Diseases 0.000 description 1
- 230000003860 sleep quality Effects 0.000 description 1
- 230000008925 spontaneous activity Effects 0.000 description 1
- 210000003523 substantia nigra Anatomy 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 230000001519 thymoleptic effect Effects 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- WFPIAZLQTJBIFN-DVZOWYKESA-N zuclopenthixol Chemical compound C1CN(CCO)CCN1CC\C=C\1C2=CC(Cl)=CC=C2SC2=CC=CC=C2/1 WFPIAZLQTJBIFN-DVZOWYKESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK912065A DK206591D0 (da) | 1991-12-23 | 1991-12-23 | Behandling af psykoser |
| PCT/DK1992/000390 WO1993012790A1 (en) | 1991-12-23 | 1992-12-21 | Use of arylindole derivatives for the treatment of psychoses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK75794A3 true SK75794A3 (en) | 1995-04-12 |
Family
ID=8109829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK757-94A SK75794A3 (en) | 1991-12-23 | 1992-12-21 | Arylindole derivatives |
Country Status (11)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5554030A (en) * | 1994-06-30 | 1996-09-10 | Minnesota Mining And Manufacturing Company | Method for bonding non-amalgam restorative materials to dental surfaces |
| UA44838C2 (uk) * | 1996-03-25 | 2002-03-15 | Елі Ліллі Енд Компані | Спосіб лікування мігрені |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
| GB8908085D0 (en) * | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
| DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
| DK238190D0 (da) * | 1990-10-03 | 1990-10-03 | Lundbeck & Co As H | Depotderivater |
| DK8492D0 (da) * | 1992-01-23 | 1992-01-23 | Lundbeck & Co As H | Behandling af psykoser |
-
1991
- 1991-12-23 DK DK912065A patent/DK206591D0/da not_active Application Discontinuation
-
1992
- 1992-12-21 RU RU94031165/14A patent/RU94031165A/ru unknown
- 1992-12-21 SK SK757-94A patent/SK75794A3/sk unknown
- 1992-12-21 CA CA002126571A patent/CA2126571A1/en not_active Abandoned
- 1992-12-21 EP EP93902096A patent/EP0618799A1/en not_active Ceased
- 1992-12-21 CZ CZ941539A patent/CZ153994A3/cs unknown
- 1992-12-21 WO PCT/DK1992/000390 patent/WO1993012790A1/en not_active Application Discontinuation
- 1992-12-21 JP JP5511365A patent/JPH07502517A/ja active Pending
- 1992-12-21 AU AU33452/93A patent/AU668537B2/en not_active Ceased
- 1992-12-23 ZA ZA9210001A patent/ZA9210001B/xx unknown
-
1994
- 1994-06-22 NO NO942378A patent/NO942378L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2126571A1 (en) | 1993-07-08 |
| DK206591D0 (da) | 1991-12-23 |
| AU3345293A (en) | 1993-07-28 |
| CZ153994A3 (en) | 1995-06-14 |
| EP0618799A1 (en) | 1994-10-12 |
| WO1993012790A1 (en) | 1993-07-08 |
| RU94031165A (ru) | 1996-06-20 |
| NO942378D0 (enrdf_load_stackoverflow) | 1994-06-22 |
| JPH07502517A (ja) | 1995-03-16 |
| ZA9210001B (en) | 1994-01-13 |
| NO942378L (no) | 1994-06-22 |
| AU668537B2 (en) | 1996-05-09 |
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