SK7362003A3 - 4-(Biphenylcarbonylamino)piperidine derivatives as MTP inhibitors - Google Patents

4-(Biphenylcarbonylamino)piperidine derivatives as MTP inhibitors Download PDF

Info

Publication number
SK7362003A3
SK7362003A3 SK736-2003A SK7362003A SK7362003A3 SK 7362003 A3 SK7362003 A3 SK 7362003A3 SK 7362003 A SK7362003 A SK 7362003A SK 7362003 A3 SK7362003 A3 SK 7362003A3
Authority
SK
Slovakia
Prior art keywords
biphenyl
piperidine
carbonylamino
methyl
formula
Prior art date
Application number
SK736-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Alyx-Caroline Guevel
Didier Festal
Francois Collonges
Daniel Guerrier
Oliver Chevreuil
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SK7362003A3 publication Critical patent/SK7362003A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
SK736-2003A 2000-11-23 2001-10-25 4-(Biphenylcarbonylamino)piperidine derivatives as MTP inhibitors SK7362003A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015143A FR2816940A1 (fr) 2000-11-23 2000-11-23 Derives de 4-(biphenylcarbonylamino)-piperidine, compositions les contenant et leur utilisation
PCT/EP2001/012326 WO2002042291A1 (en) 2000-11-23 2001-10-25 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors

Publications (1)

Publication Number Publication Date
SK7362003A3 true SK7362003A3 (en) 2003-11-04

Family

ID=8856805

Family Applications (1)

Application Number Title Priority Date Filing Date
SK736-2003A SK7362003A3 (en) 2000-11-23 2001-10-25 4-(Biphenylcarbonylamino)piperidine derivatives as MTP inhibitors

Country Status (20)

Country Link
US (1) US20040034028A1 (cs)
EP (1) EP1335912A1 (cs)
JP (1) JP2004514676A (cs)
KR (1) KR20030060954A (cs)
CN (1) CN1476445A (cs)
AR (1) AR031499A1 (cs)
AU (1) AU2002221745A1 (cs)
BR (1) BR0115520A (cs)
CA (1) CA2429326A1 (cs)
CZ (1) CZ20031619A3 (cs)
FR (1) FR2816940A1 (cs)
HU (1) HUP0400819A2 (cs)
IL (1) IL155986A0 (cs)
MX (1) MXPA03004540A (cs)
NO (1) NO20032315D0 (cs)
PE (1) PE20020595A1 (cs)
PL (1) PL365939A1 (cs)
RU (1) RU2003117458A (cs)
SK (1) SK7362003A3 (cs)
WO (1) WO2002042291A1 (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE05452B1 (et) 2001-06-28 2011-08-15 Pfizer Products Inc. Triamiidasendatud indoolid, bensofuraanid ja bensotiofeenid kui mikrosomaalse trigltseriidide transportvalgu (MTP) ja/v?i apolipoproteiin B (apoB) sekretsiooni inhibiitorid
CN101838218A (zh) 2002-02-28 2010-09-22 日本烟草产业株式会社 酯化合物及其医药用途
FR2856685B1 (fr) * 2003-06-25 2005-09-23 Merck Sante Sas Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
JP4832897B2 (ja) 2003-08-29 2011-12-07 日本たばこ産業株式会社 エステル誘導体及びその医薬用途
FR2865733B1 (fr) * 2004-02-04 2007-10-12 Merck Sante Sas Derives de thiazolylimidazole, leurs procedes de preparation, les compositions pharmaceutiques qui les contiennent et leurs applications en medecine
FR2871463B1 (fr) * 2004-06-11 2006-09-22 Merck Sante Soc Par Actions Si Derives a structure aroyl-o-piperidine, leurs procedes de preparation, les compositions pharmaceutiques qui les contiennent et leurs applications en therapeutique
US8101774B2 (en) 2004-10-18 2012-01-24 Japan Tobacco Inc. Ester derivatives and medicinal use thereof
FR2884831B1 (fr) * 2005-04-22 2007-08-10 Merck Sante Soc Par Actions Si Methode de criblage de composes inhibiteurs de la mtp
ATE469122T1 (de) 2006-10-24 2010-06-15 Janssen Pharmaceutica Nv Mtp-inhibierende tetrahydronaphthalin-1- carbonsäurederivate
JO2653B1 (en) * 2006-10-24 2012-06-17 شركة جانسين فارماسوتيكا ان. في Tetrahydroflavin 1-carboxylic acid substituted with pyridine or pyrazine inhibit MTB
MX2009006543A (es) * 2006-12-20 2009-06-26 Amgen Inc Compuestos heterociclicos y su uso en el tratamiento de la inflamacion, angiogenesis y cancer.
AR074466A1 (es) 2008-12-05 2011-01-19 Sanofi Aventis Piperidina espiro pirrolidinona y piperidinona sustituidas y su uso terapeutico en enfermedades mediadas por la modulacion de los receptores h3.
MX2012002274A (es) 2009-09-03 2012-09-07 Bioenergenix Compuestos heterociclicos para la inhibicion de pask.
EP2661431B1 (en) 2011-01-05 2018-07-11 Bioenergenix Heterocyclic compounds for the inhibition of pask
BR112013022147A2 (pt) 2011-03-02 2017-04-25 Bioenergenix composto, composição farmacêutica, método de inibição da pask, método de tratamento de uma doença, método para alcançar um efeito em um paciente e método de tratamento de uma doença mediada pela pask
US8916561B2 (en) 2011-03-02 2014-12-23 Bioenergenix, Llc Substituted quinoxaline compounds for the inhibition of PASK
EP3053911B1 (en) * 2013-09-30 2020-01-22 The University of Tokyo Adiponectin receptor-activating compound

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8528234D0 (en) * 1985-11-15 1985-12-18 Wyeth John & Brother Ltd Heterocyclic compounds
US5595872A (en) * 1992-03-06 1997-01-21 Bristol-Myers Squibb Company Nucleic acids encoding microsomal trigyceride transfer protein
CA2123728A1 (en) * 1993-05-21 1994-11-22 Noriyoshi Sueda Urea derivatives and their use as acat inhibitors
US6130232A (en) * 1995-10-13 2000-10-10 Banyu Pharmaceutical Coaltd Substituted piperidine derivatives as muscarinic M3 receptor antagonists
AU2793197A (en) * 1996-05-31 1998-01-05 Banyu Pharmaceutical Co., Ltd. 1,4-disubstituted piperidine derivatives

Also Published As

Publication number Publication date
CN1476445A (zh) 2004-02-18
BR0115520A (pt) 2003-09-16
WO2002042291A1 (en) 2002-05-30
FR2816940A1 (fr) 2002-05-24
JP2004514676A (ja) 2004-05-20
US20040034028A1 (en) 2004-02-19
PL365939A1 (en) 2005-01-24
HUP0400819A2 (hu) 2004-07-28
CZ20031619A3 (cs) 2003-09-17
CA2429326A1 (en) 2002-05-30
NO20032315L (no) 2003-05-22
AR031499A1 (es) 2003-09-24
NO20032315D0 (no) 2003-05-22
MXPA03004540A (es) 2003-09-10
KR20030060954A (ko) 2003-07-16
IL155986A0 (en) 2003-12-23
AU2002221745A1 (en) 2002-06-03
EP1335912A1 (en) 2003-08-20
PE20020595A1 (es) 2002-07-08
RU2003117458A (ru) 2004-12-27

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