MXPA03004540A - Derivados de 4-(bifenilcarbonilamino) piperidina, composiciones que los comprenden y uso de los mismos. - Google Patents

Derivados de 4-(bifenilcarbonilamino) piperidina, composiciones que los comprenden y uso de los mismos.

Info

Publication number
MXPA03004540A
MXPA03004540A MXPA03004540A MXPA03004540A MXPA03004540A MX PA03004540 A MXPA03004540 A MX PA03004540A MX PA03004540 A MXPA03004540 A MX PA03004540A MX PA03004540 A MXPA03004540 A MX PA03004540A MX PA03004540 A MXPA03004540 A MX PA03004540A
Authority
MX
Mexico
Prior art keywords
biphenylcarbonylamino
piperidine derivatives
mtp inhibitors
mtp
inhibitors
Prior art date
Application number
MXPA03004540A
Other languages
English (en)
Inventor
Didier Festal
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of MXPA03004540A publication Critical patent/MXPA03004540A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
MXPA03004540A 2000-11-23 2001-10-25 Derivados de 4-(bifenilcarbonilamino) piperidina, composiciones que los comprenden y uso de los mismos. MXPA03004540A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015143A FR2816940A1 (fr) 2000-11-23 2000-11-23 Derives de 4-(biphenylcarbonylamino)-piperidine, compositions les contenant et leur utilisation
PCT/EP2001/012326 WO2002042291A1 (en) 2000-11-23 2001-10-25 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors

Publications (1)

Publication Number Publication Date
MXPA03004540A true MXPA03004540A (es) 2003-09-10

Family

ID=8856805

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03004540A MXPA03004540A (es) 2000-11-23 2001-10-25 Derivados de 4-(bifenilcarbonilamino) piperidina, composiciones que los comprenden y uso de los mismos.

Country Status (20)

Country Link
US (1) US20040034028A1 (es)
EP (1) EP1335912A1 (es)
JP (1) JP2004514676A (es)
KR (1) KR20030060954A (es)
CN (1) CN1476445A (es)
AR (1) AR031499A1 (es)
AU (1) AU2002221745A1 (es)
BR (1) BR0115520A (es)
CA (1) CA2429326A1 (es)
CZ (1) CZ20031619A3 (es)
FR (1) FR2816940A1 (es)
HU (1) HUP0400819A2 (es)
IL (1) IL155986A0 (es)
MX (1) MXPA03004540A (es)
NO (1) NO20032315D0 (es)
PE (1) PE20020595A1 (es)
PL (1) PL365939A1 (es)
RU (1) RU2003117458A (es)
SK (1) SK7362003A3 (es)
WO (1) WO2002042291A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ528752A (en) 2001-06-28 2006-06-30 Pfizer Prod Inc Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (APO B) secretion
RU2293721C2 (ru) 2002-02-28 2007-02-20 Джапан Тобакко Инк. Сложноэфирные соединения и их применение в медицине
FR2856685B1 (fr) 2003-06-25 2005-09-23 Merck Sante Sas Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
WO2005021486A1 (ja) 2003-08-29 2005-03-10 Japan Tobacco Inc. エステル誘導体及びその医薬用途
FR2865733B1 (fr) * 2004-02-04 2007-10-12 Merck Sante Sas Derives de thiazolylimidazole, leurs procedes de preparation, les compositions pharmaceutiques qui les contiennent et leurs applications en medecine
FR2871463B1 (fr) * 2004-06-11 2006-09-22 Merck Sante Soc Par Actions Si Derives a structure aroyl-o-piperidine, leurs procedes de preparation, les compositions pharmaceutiques qui les contiennent et leurs applications en therapeutique
US8101774B2 (en) 2004-10-18 2012-01-24 Japan Tobacco Inc. Ester derivatives and medicinal use thereof
FR2884831B1 (fr) * 2005-04-22 2007-08-10 Merck Sante Soc Par Actions Si Methode de criblage de composes inhibiteurs de la mtp
JO2653B1 (en) * 2006-10-24 2012-06-17 شركة جانسين فارماسوتيكا ان. في Tetrahydroflavin 1-carboxylic acid substituted with pyridine or pyrazine inhibit MTB
KR101387459B1 (ko) 2006-10-24 2014-05-14 얀센 파마슈티카 엔.브이. Ｍｔｐ를 저해하는 테트라하이드로-나프탈렌-1-카복실산 유도체
MX2009006543A (es) * 2006-12-20 2009-06-26 Amgen Inc Compuestos heterociclicos y su uso en el tratamiento de la inflamacion, angiogenesis y cancer.
AR074466A1 (es) 2008-12-05 2011-01-19 Sanofi Aventis Piperidina espiro pirrolidinona y piperidinona sustituidas y su uso terapeutico en enfermedades mediadas por la modulacion de los receptores h3.
CA2772714C (en) 2009-09-03 2017-09-26 Bioenergenix Heterocyclic compounds for the inhibition of pask
US9073902B2 (en) 2011-01-05 2015-07-07 Bioenergenix, Llc Substituted quinoxaline carboxylic acid compounds for the inhibition of PASK
US8912188B2 (en) 2011-03-02 2014-12-16 Bioenergenix, Llc Substituted quinoxaline carboxylic acids for the inhibition of PASK
US8916561B2 (en) 2011-03-02 2014-12-23 Bioenergenix, Llc Substituted quinoxaline compounds for the inhibition of PASK
EP3053911B1 (en) * 2013-09-30 2020-01-22 The University of Tokyo Adiponectin receptor-activating compound

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8528234D0 (en) * 1985-11-15 1985-12-18 Wyeth John & Brother Ltd Heterocyclic compounds
US5595872A (en) * 1992-03-06 1997-01-21 Bristol-Myers Squibb Company Nucleic acids encoding microsomal trigyceride transfer protein
CA2123728A1 (en) * 1993-05-21 1994-11-22 Noriyoshi Sueda Urea derivatives and their use as acat inhibitors
AU7145996A (en) * 1995-10-13 1997-04-30 Banyu Pharmaceutical Co., Ltd. Substituted heteroaromatic derivatives
WO1997045414A1 (fr) * 1996-05-31 1997-12-04 Banyu Pharmaceutical Co., Ltd. Derives de piperidine a disubstitution en positions 1,4

Also Published As

Publication number Publication date
NO20032315L (no) 2003-05-22
RU2003117458A (ru) 2004-12-27
EP1335912A1 (en) 2003-08-20
JP2004514676A (ja) 2004-05-20
WO2002042291A1 (en) 2002-05-30
CN1476445A (zh) 2004-02-18
CZ20031619A3 (cs) 2003-09-17
HUP0400819A2 (hu) 2004-07-28
US20040034028A1 (en) 2004-02-19
AU2002221745A1 (en) 2002-06-03
NO20032315D0 (no) 2003-05-22
KR20030060954A (ko) 2003-07-16
IL155986A0 (en) 2003-12-23
AR031499A1 (es) 2003-09-24
BR0115520A (pt) 2003-09-16
SK7362003A3 (en) 2003-11-04
CA2429326A1 (en) 2002-05-30
PE20020595A1 (es) 2002-07-08
FR2816940A1 (fr) 2002-05-24
PL365939A1 (en) 2005-01-24

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