SK71199A3 - Preparation of [1s-[1a,2b,3b,4a(s*)]]-4-[7-[[1-(3-chloro-2- thienyl)methyl]propyl]amino]-3h-imidazo[4,5-b]pyridin-3-yl]-n- ethyl-2,3-dihydroxycyclopentanecarboxamide - Google Patents

Preparation of [1s-[1a,2b,3b,4a(s*)]]-4-[7-[[1-(3-chloro-2- thienyl)methyl]propyl]amino]-3h-imidazo[4,5-b]pyridin-3-yl]-n- ethyl-2,3-dihydroxycyclopentanecarboxamide Download PDF

Info

Publication number
SK71199A3
SK71199A3 SK711-99A SK71199A SK71199A3 SK 71199 A3 SK71199 A3 SK 71199A3 SK 71199 A SK71199 A SK 71199A SK 71199 A3 SK71199 A3 SK 71199A3
Authority
SK
Slovakia
Prior art keywords
amino
chloro
thienyl
methyl
propyl
Prior art date
Application number
SK711-99A
Other languages
English (en)
Slovak (sk)
Inventor
Michael K O'brien
Herve Garcia
Patrick Leon
Tory H Powner
Laurence W Reilly
Harshavadan C Shah
Michael D Thompson
Ching T Tsuei
Benoit J Vanasse
Francis L Walther
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of SK71199A3 publication Critical patent/SK71199A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK711-99A 1996-12-11 1997-11-24 Preparation of [1s-[1a,2b,3b,4a(s*)]]-4-[7-[[1-(3-chloro-2- thienyl)methyl]propyl]amino]-3h-imidazo[4,5-b]pyridin-3-yl]-n- ethyl-2,3-dihydroxycyclopentanecarboxamide SK71199A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3276496P 1996-12-11 1996-12-11
PCT/US1997/021439 WO1998025921A1 (en) 1996-12-11 1997-11-24 PREPARATION OF [1S-[1a,2b,3b,4a(S*)]]-4-[7-[[1-(3-CHLORO-2-THIENYL) METHYL]PROPYL]AMINO]-3H-IMIDAZO[4,5-b]PYRIDIN-3-yl]-N-ETHYL-2,3-DIHYDROXYCYCLOPENTANECARBOXAMIDE

Publications (1)

Publication Number Publication Date
SK71199A3 true SK71199A3 (en) 2000-07-11

Family

ID=21866680

Family Applications (1)

Application Number Title Priority Date Filing Date
SK711-99A SK71199A3 (en) 1996-12-11 1997-11-24 Preparation of [1s-[1a,2b,3b,4a(s*)]]-4-[7-[[1-(3-chloro-2- thienyl)methyl]propyl]amino]-3h-imidazo[4,5-b]pyridin-3-yl]-n- ethyl-2,3-dihydroxycyclopentanecarboxamide

Country Status (27)

Country Link
US (2) US6143894A (ko)
EP (2) EP0946550B1 (ko)
JP (1) JP2001506626A (ko)
KR (4) KR20060002030A (ko)
CN (3) CN1660842A (ko)
AP (1) AP1063A (ko)
AT (1) ATE301120T1 (ko)
AU (1) AU738581B2 (ko)
BG (1) BG63805B1 (ko)
BR (1) BR9713705A (ko)
CA (1) CA2274630C (ko)
DE (1) DE69733897T2 (ko)
DK (1) DK0946550T3 (ko)
EA (1) EA001989B1 (ko)
ES (1) ES2242984T3 (ko)
HK (2) HK1023998A1 (ko)
HU (1) HUP0000342A3 (ko)
IL (1) IL130397A (ko)
MX (1) MXPA03006730A (ko)
NO (2) NO319722B1 (ko)
OA (1) OA11061A (ko)
PT (1) PT946550E (ko)
SI (1) SI0946550T1 (ko)
SK (1) SK71199A3 (ko)
UA (1) UA54479C2 (ko)
WO (1) WO1998025921A1 (ko)
ZA (1) ZA9711035B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1140933T3 (da) 1998-12-31 2004-12-20 Aventis Pharma Inc Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
FR2846656B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2095960T3 (es) * 1990-09-25 1997-03-01 Rhone Poulenc Rorer Int Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
HRP980375A2 (en) * 1997-07-03 1999-04-30 Argyrios Georgios Arvanitis Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
ES2191489T3 (es) * 1998-12-21 2003-09-01 Aventis Pharma Inc Proceso para preparar derivados de deaza-adenosina sustituidos en n6.

Also Published As

Publication number Publication date
WO1998025921A1 (en) 1998-06-18
KR100571690B1 (ko) 2006-04-18
SI0946550T1 (en) 2005-10-31
CN1090630C (zh) 2002-09-11
CN1394859A (zh) 2003-02-05
CN1660842A (zh) 2005-08-31
EP0946550A4 (en) 2003-05-14
CN1191251C (zh) 2005-03-02
IL130397A0 (en) 2000-06-01
EA001989B1 (ru) 2001-10-22
JP2001506626A (ja) 2001-05-22
EA199900527A1 (ru) 2000-02-28
UA54479C2 (uk) 2003-03-17
BG63805B1 (bg) 2003-01-31
HUP0000342A2 (hu) 2000-10-28
EP0946550B1 (en) 2005-08-03
NO992795L (no) 1999-08-10
HUP0000342A3 (en) 2001-01-29
KR20060002030A (ko) 2006-01-06
KR20060002029A (ko) 2006-01-06
KR20000057505A (ko) 2000-09-15
KR20050046793A (ko) 2005-05-18
NO20052327L (no) 1999-08-10
HK1023998A1 (en) 2000-09-29
BR9713705A (pt) 2000-05-09
EP1609791A1 (en) 2005-12-28
KR100510389B1 (ko) 2005-08-31
PT946550E (pt) 2005-09-30
IL130397A (en) 2005-11-20
ZA9711035B (en) 1998-06-15
AP1063A (en) 2002-04-26
OA11061A (en) 2002-02-27
BG103484A (en) 2000-06-30
ATE301120T1 (de) 2005-08-15
DE69733897D1 (de) 2005-09-08
NO20052327D0 (no) 2005-05-12
HK1051862A1 (en) 2003-08-22
ES2242984T3 (es) 2005-11-16
AU5360798A (en) 1998-07-03
US6235909B1 (en) 2001-05-22
NO319722B1 (no) 2005-09-05
AP9901550A0 (en) 1999-06-30
US6143894A (en) 2000-11-07
DK0946550T3 (da) 2005-08-29
CA2274630C (en) 2000-10-03
EP0946550A1 (en) 1999-10-06
NO992795D0 (no) 1999-06-09
CN1240445A (zh) 2000-01-05
MXPA03006730A (es) 2003-10-24
DE69733897T2 (de) 2006-06-01
AU738581B2 (en) 2001-09-20

Similar Documents

Publication Publication Date Title
EP2235001B1 (en) Process for preparing pyridinone compounds
RU2351590C2 (ru) Способ получения диариламина
KR100742013B1 (ko) 4-아릴-니코틴아마이드 유도체의 제조 방법
CN111315742B (zh) 制备氨基嘧啶衍生物的方法
SK71199A3 (en) Preparation of [1s-[1a,2b,3b,4a(s*)]]-4-[7-[[1-(3-chloro-2- thienyl)methyl]propyl]amino]-3h-imidazo[4,5-b]pyridin-3-yl]-n- ethyl-2,3-dihydroxycyclopentanecarboxamide
IL152921A (en) Preparation of 4-hydroxy-3-nitro-2(1h)-pyridone from 2-hydroxy-3-cyano-4-methoxypyridine
MXPA99005488A (en) PREPARATION OF [1S-[1a,2b,3b,4a(S*)]]-4-[7-[[1-(3-CHLORO-2-THIENYL) METHYL]PROPYL]AMINO]-3H-IMIDAZO[4,5-b]PYRIDIN-3-yl]-N-ETHYL-2,3-DIHYDROXYCYCLOPENTANECARBOXAMIDE
CZ208599A3 (cs) Způsob přípravy [lS-[la,2b,3b,4a(S)]]-4-[7-[[l- (3-Cloro-2-thienyl) methyl]propyl]amino]-3Himidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3- dihydroxycyklopentankarbokamidu
EP1392678A2 (en) Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof
NZ538325A (en) Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof