SK59995A3 - Process for preparing enantiomerically pure 6-£(4-chlorophenyl) (1h-triazol-1,2,4-triazol-1-yl) methyl|-1-methyl-1h-benzotriazole, intermediates for its production and method of its production - Google Patents

Process for preparing enantiomerically pure 6-£(4-chlorophenyl) (1h-triazol-1,2,4-triazol-1-yl) methyl|-1-methyl-1h-benzotriazole, intermediates for its production and method of its production Download PDF

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Publication number
SK59995A3
SK59995A3 SK599-95A SK59995A SK59995A3 SK 59995 A3 SK59995 A3 SK 59995A3 SK 59995 A SK59995 A SK 59995A SK 59995 A3 SK59995 A3 SK 59995A3
Authority
SK
Slovakia
Prior art keywords
formula
acid
methyl
reaction
mixture
Prior art date
Application number
SK599-95A
Other languages
English (en)
Slovak (sk)
Inventor
Albert L A Willemsens
Walter L A Verstappen
Alex H Copmans
A M J Vendendriessche
Knaep Alfons G M De
Marc G Venet
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SK59995A3 publication Critical patent/SK59995A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK599-95A 1992-11-10 1993-11-02 Process for preparing enantiomerically pure 6-£(4-chlorophenyl) (1h-triazol-1,2,4-triazol-1-yl) methyl|-1-methyl-1h-benzotriazole, intermediates for its production and method of its production SK59995A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92203443 1992-11-10
PCT/EP1993/003066 WO1994011364A1 (en) 1992-11-10 1993-11-02 Process for preparing enantiomerically pure 6-[(4-chlorophenyl)(1h^_-triazol-1,2,4-triazol-1-yl)methyl]-1-methyl-1h^_-benzotriazole

Publications (1)

Publication Number Publication Date
SK59995A3 true SK59995A3 (en) 1995-10-11

Family

ID=8211029

Family Applications (1)

Application Number Title Priority Date Filing Date
SK599-95A SK59995A3 (en) 1992-11-10 1993-11-02 Process for preparing enantiomerically pure 6-£(4-chlorophenyl) (1h-triazol-1,2,4-triazol-1-yl) methyl|-1-methyl-1h-benzotriazole, intermediates for its production and method of its production

Country Status (18)

Country Link
US (2) US5663354A (fi)
EP (1) EP0668861A1 (fi)
JP (1) JPH08502990A (fi)
AU (1) AU679704B2 (fi)
BG (1) BG99594A (fi)
BR (1) BR9307409A (fi)
CA (1) CA2148489A1 (fi)
CZ (1) CZ115195A3 (fi)
FI (1) FI952251A0 (fi)
HU (1) HUT72073A (fi)
NO (1) NO951808L (fi)
NZ (1) NZ257551A (fi)
PL (1) PL176059B1 (fi)
RO (1) RO114327B1 (fi)
RU (1) RU95112576A (fi)
SG (1) SG50476A1 (fi)
SK (1) SK59995A3 (fi)
WO (1) WO1994011364A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5663354A (en) * 1992-11-10 1997-09-02 Janssen Pharmaceutica, N.V. Process for preparing enantiomerically pure 6-[(4-chlorophenyl) (1H-1,2,4-triazol-1-yl) methyl]-1-methyl-1H-benzotrizole
US8795629B2 (en) * 2009-02-13 2014-08-05 Brookhaven Science Associates, Llc Radio-methyl vorozole and methods for making and using the same
US8207352B2 (en) * 2009-10-08 2012-06-26 Drug Process Licensing Associates LLC Process for the manufacture of enantiomerically pure antifungal azoles as ravuconazole and isavuconazole
WO2019135991A1 (en) 2018-01-03 2019-07-11 Ecolab Usa Inc. Benzotriazole derivatives as corrosion inhibitors
CN115650962B (zh) * 2022-10-31 2024-07-30 吉林大学 一种用于钯催化偶联反应的荧光配体化合物及制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943574A (en) * 1987-06-01 1990-07-24 Janssen Pharmaceutica N.V. (1H-azol-1-ylmethyl) substituted benzotriazole derivatives and pharmaceutical compositions containing them
NZ224714A (en) * 1987-06-01 1990-03-27 Janssen Pharmaceutica Nv Substituted benzotriazole derivatives and pharmaceutical compositions
CA2002859C (en) * 1988-11-29 1998-12-29 Jean P. F. Van Wauwe Method of treating epithelial disorders
US5663354A (en) * 1992-11-10 1997-09-02 Janssen Pharmaceutica, N.V. Process for preparing enantiomerically pure 6-[(4-chlorophenyl) (1H-1,2,4-triazol-1-yl) methyl]-1-methyl-1H-benzotrizole

Also Published As

Publication number Publication date
HUT72073A (en) 1996-03-28
NO951808D0 (no) 1995-05-09
US5746840A (en) 1998-05-05
US5663354A (en) 1997-09-02
AU5420394A (en) 1994-06-08
FI952251A (fi) 1995-05-09
CZ115195A3 (en) 1995-11-15
RU95112576A (ru) 1997-03-20
PL176059B1 (pl) 1999-03-31
WO1994011364A1 (en) 1994-05-26
FI952251A0 (fi) 1995-05-09
PL308905A1 (en) 1995-09-04
AU679704B2 (en) 1997-07-10
SG50476A1 (en) 1998-07-20
RO114327B1 (ro) 1999-03-30
CA2148489A1 (en) 1994-05-26
NZ257551A (en) 1995-10-26
BR9307409A (pt) 1999-08-24
JPH08502990A (ja) 1996-04-02
EP0668861A1 (en) 1995-08-30
NO951808L (no) 1995-05-09
BG99594A (bg) 1996-01-31

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