SK5922003A3 - Repinotan kit - Google Patents
Repinotan kit Download PDFInfo
- Publication number
- SK5922003A3 SK5922003A3 SK592-2003A SK5922003A SK5922003A3 SK 5922003 A3 SK5922003 A3 SK 5922003A3 SK 5922003 A SK5922003 A SK 5922003A SK 5922003 A3 SK5922003 A3 SK 5922003A3
- Authority
- SK
- Slovakia
- Prior art keywords
- acid
- repinotan
- physiologically acceptable
- repinotane
- solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10058119A DE10058119A1 (de) | 2000-11-22 | 2000-11-22 | Pepinotan-Kit |
| PCT/EP2001/012968 WO2002041881A2 (de) | 2000-11-22 | 2001-11-09 | Repinotan-kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK5922003A3 true SK5922003A3 (en) | 2003-11-04 |
Family
ID=7664358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK592-2003A SK5922003A3 (en) | 2000-11-22 | 2001-11-09 | Repinotan kit |
Country Status (37)
| Country | Link |
|---|---|
| US (2) | US6605255B2 (es) |
| EP (1) | EP1339403B1 (es) |
| JP (2) | JP2004517824A (es) |
| KR (1) | KR20030096237A (es) |
| CN (2) | CN1518446A (es) |
| AR (1) | AR031761A1 (es) |
| AT (1) | ATE284212T1 (es) |
| AU (1) | AU2002227912A1 (es) |
| BG (1) | BG107803A (es) |
| BR (1) | BR0115518A (es) |
| CA (1) | CA2429310A1 (es) |
| CZ (1) | CZ20031401A3 (es) |
| DE (2) | DE10058119A1 (es) |
| DO (1) | DOP2001000293A (es) |
| EC (1) | ECSP034617A (es) |
| EE (1) | EE200300242A (es) |
| ES (1) | ES2234922T3 (es) |
| GT (1) | GT200100236A (es) |
| HN (1) | HN2001000262A (es) |
| HR (1) | HRP20030490A2 (es) |
| HU (1) | HUP0303294A2 (es) |
| IL (1) | IL155975A0 (es) |
| MA (1) | MA26059A1 (es) |
| MX (1) | MXPA03004499A (es) |
| MY (1) | MY118345A (es) |
| NO (1) | NO20032212D0 (es) |
| NZ (1) | NZ525964A (es) |
| PE (1) | PE20020533A1 (es) |
| PL (1) | PL361628A1 (es) |
| PT (1) | PT1339403E (es) |
| RU (1) | RU2003118583A (es) |
| SI (1) | SI1339403T1 (es) |
| SK (1) | SK5922003A3 (es) |
| SV (1) | SV2003000744A (es) |
| UY (1) | UY27027A1 (es) |
| WO (1) | WO2002041881A2 (es) |
| ZA (1) | ZA200303888B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861422B2 (en) * | 2003-02-26 | 2005-03-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions |
| DE102004010050A1 (de) * | 2004-03-02 | 2005-09-22 | Bayer Healthcare Ag | Spezifische monoklonale und polyklonale Antikörper für Repinotan und dessen ringoffene Form |
| DE102004029784A1 (de) * | 2004-06-21 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel |
| DE102004033670A1 (de) * | 2004-07-09 | 2006-02-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel |
| US7759485B2 (en) * | 2004-08-14 | 2010-07-20 | Boehringer Ingelheim International Gmbh | Process for the manufacture of dihydropteridinones |
| US20060035903A1 (en) * | 2004-08-14 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Storage stable perfusion solution for dihydropteridinones |
| US20060058311A1 (en) | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
| US7728134B2 (en) * | 2004-08-14 | 2010-06-01 | Boehringer Ingelheim International Gmbh | Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
| US20060074088A1 (en) * | 2004-08-14 | 2006-04-06 | Boehringer Ingelheim International Gmbh | Dihydropteridinones for the treatment of cancer diseases |
| EP1630163A1 (de) * | 2004-08-25 | 2006-03-01 | Boehringer Ingelheim Pharma GmbH & Co.KG | Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| EP1632493A1 (de) * | 2004-08-25 | 2006-03-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102004058337A1 (de) * | 2004-12-02 | 2006-06-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten |
| US7439358B2 (en) | 2006-02-08 | 2008-10-21 | Boehringer Ingelheim International Gmbh | Specific salt, anhydrous and crystalline form of a dihydropteridione derivative |
| WO2009019205A1 (en) * | 2007-08-03 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Crystalline form of a dihydropteridione derivative |
| US8546566B2 (en) | 2010-10-12 | 2013-10-01 | Boehringer Ingelheim International Gmbh | Process for manufacturing dihydropteridinones and intermediates thereof |
| US9358233B2 (en) | 2010-11-29 | 2016-06-07 | Boehringer Ingelheim International Gmbh | Method for treating acute myeloid leukemia |
| US9370535B2 (en) | 2011-05-17 | 2016-06-21 | Boehringer Ingelheim International Gmbh | Method for treatment of advanced solid tumors |
| US20150031699A1 (en) | 2013-07-26 | 2015-01-29 | Boehringer Ingelheim International Gmbh | Treatment of myelodysplastic syndrome |
| US9867831B2 (en) | 2014-10-01 | 2018-01-16 | Boehringer Ingelheim International Gmbh | Combination treatment of acute myeloid leukemia and myelodysplastic syndrome |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| DE19522088A1 (de) * | 1995-06-19 | 1997-01-02 | Bayer Ag | Benzisothiazolyl-substituierte Aminomethylchromane |
| DE19543476A1 (de) * | 1995-11-22 | 1997-05-28 | Troponwerke Gmbh & Co Kg | Verwendung von substituierten Aminomethyl-chromanen zur Behandlung von Schädel-Hirn-Trauma |
| DE19751949A1 (de) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
| DE19754573A1 (de) * | 1997-12-09 | 1999-06-10 | Bayer Ag | Pharmazeutische Zusammensetzung zur Behandlung von Schlaganfall und Schädel-Hirn-Trauma |
| AU757405B2 (en) * | 1998-03-10 | 2003-02-20 | Bayer Aktiengesellschaft | Integrated assay device and methods of production and use |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| DE19936281C2 (de) | 1999-08-02 | 2002-04-04 | Bayer Ag | Verfahren zur Gefriertrocknung |
-
2000
- 2000-11-22 DE DE10058119A patent/DE10058119A1/de not_active Ceased
-
2001
- 2001-11-09 ES ES01989448T patent/ES2234922T3/es not_active Expired - Lifetime
- 2001-11-09 CZ CZ20031401A patent/CZ20031401A3/cs unknown
- 2001-11-09 PL PL36162801A patent/PL361628A1/xx not_active Application Discontinuation
- 2001-11-09 RU RU2003118583/15A patent/RU2003118583A/ru not_active Application Discontinuation
- 2001-11-09 BR BR0115518-0A patent/BR0115518A/pt not_active IP Right Cessation
- 2001-11-09 MX MXPA03004499A patent/MXPA03004499A/es unknown
- 2001-11-09 AU AU2002227912A patent/AU2002227912A1/en not_active Abandoned
- 2001-11-09 IL IL15597501A patent/IL155975A0/xx unknown
- 2001-11-09 PT PT01989448T patent/PT1339403E/pt unknown
- 2001-11-09 AT AT01989448T patent/ATE284212T1/de not_active IP Right Cessation
- 2001-11-09 KR KR10-2003-7006854A patent/KR20030096237A/ko not_active Application Discontinuation
- 2001-11-09 CA CA002429310A patent/CA2429310A1/en not_active Abandoned
- 2001-11-09 JP JP2002544060A patent/JP2004517824A/ja active Pending
- 2001-11-09 HU HU0303294A patent/HUP0303294A2/hu unknown
- 2001-11-09 CN CNA018221440A patent/CN1518446A/zh active Pending
- 2001-11-09 WO PCT/EP2001/012968 patent/WO2002041881A2/de not_active Application Discontinuation
- 2001-11-09 NZ NZ525964A patent/NZ525964A/en unknown
- 2001-11-09 DE DE2001504790 patent/DE50104790D1/de not_active Expired - Fee Related
- 2001-11-09 EE EEP200300242A patent/EE200300242A/xx unknown
- 2001-11-09 EP EP01989448A patent/EP1339403B1/de not_active Expired - Lifetime
- 2001-11-09 SI SI200130270T patent/SI1339403T1/xx unknown
- 2001-11-09 CN CNA2005100859302A patent/CN1715279A/zh active Pending
- 2001-11-09 SK SK592-2003A patent/SK5922003A3/sk unknown
- 2001-11-16 US US09/991,222 patent/US6605255B2/en not_active Expired - Fee Related
- 2001-11-19 UY UY27027A patent/UY27027A1/es not_active Application Discontinuation
- 2001-11-20 AR ARP010105412A patent/AR031761A1/es unknown
- 2001-11-20 MY MYPI20015310A patent/MY118345A/en unknown
- 2001-11-21 SV SV2001000744A patent/SV2003000744A/es unknown
- 2001-11-21 HN HN2001000262A patent/HN2001000262A/es unknown
- 2001-11-21 DO DO2001000293A patent/DOP2001000293A/es unknown
- 2001-11-21 PE PE2001001162A patent/PE20020533A1/es not_active Application Discontinuation
- 2001-11-22 GT GT200100236A patent/GT200100236A/es unknown
-
2003
- 2003-05-12 BG BG107803A patent/BG107803A/bg unknown
- 2003-05-15 NO NO20032212A patent/NO20032212D0/no not_active Application Discontinuation
- 2003-05-20 ZA ZA200303888A patent/ZA200303888B/en unknown
- 2003-05-21 EC EC2003004617A patent/ECSP034617A/es unknown
- 2003-05-22 MA MA27170A patent/MA26059A1/fr unknown
- 2003-05-22 US US10/444,820 patent/US20030203953A1/en not_active Abandoned
- 2003-06-17 HR HR20030490A patent/HRP20030490A2/hr not_active Application Discontinuation
-
2005
- 2005-04-26 JP JP2005128270A patent/JP2005232189A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB9A | Suspension of patent application procedure |