SK4042002A3 - Parathyroid hormone analogues for the treatment of osteoporosis - Google Patents

Parathyroid hormone analogues for the treatment of osteoporosis Download PDF

Info

Publication number
SK4042002A3
SK4042002A3 SK404-2002A SK4042002A SK4042002A3 SK 4042002 A3 SK4042002 A3 SK 4042002A3 SK 4042002 A SK4042002 A SK 4042002A SK 4042002 A3 SK4042002 A3 SK 4042002A3
Authority
SK
Slovakia
Prior art keywords
leu
lys
glu
ser
amino acid
Prior art date
Application number
SK404-2002A
Other languages
English (en)
Slovak (sk)
Inventor
Jean-Rene Barbier
Paul Morley
James Whitfield
Gordon E Willick
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of SK4042002A3 publication Critical patent/SK4042002A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK404-2002A 1999-09-22 2000-09-21 Parathyroid hormone analogues for the treatment of osteoporosis SK4042002A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/406,813 US6316410B1 (en) 1999-09-22 1999-09-22 Parathyroid hormone analogues for the treatment of osteoporosis
PCT/CA2000/001083 WO2001021643A2 (en) 1999-09-22 2000-09-21 Parathyroid hormone analogues for the treatment of osteoporosis

Publications (1)

Publication Number Publication Date
SK4042002A3 true SK4042002A3 (en) 2002-12-03

Family

ID=23609550

Family Applications (1)

Application Number Title Priority Date Filing Date
SK404-2002A SK4042002A3 (en) 1999-09-22 2000-09-21 Parathyroid hormone analogues for the treatment of osteoporosis

Country Status (13)

Country Link
US (1) US6316410B1 (ja)
EP (2) EP1214348A2 (ja)
JP (1) JP4620309B2 (ja)
CN (1) CN1377371A (ja)
AU (1) AU7398000A (ja)
BR (1) BR0016306A (ja)
CA (1) CA2384341A1 (ja)
CZ (1) CZ20021026A3 (ja)
IL (1) IL148654A0 (ja)
MX (1) MXPA02002977A (ja)
SK (1) SK4042002A3 (ja)
WO (1) WO2001021643A2 (ja)
ZA (1) ZA200202162B (ja)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ553800A0 (en) * 2000-02-10 2000-03-02 Cole, Martin Terence Improvements relating to smoke detectors particularily duct monitored smoke detectors
US20040023882A1 (en) * 2002-05-16 2004-02-05 Peri Krishna G. PTH derivatives resistant to skin proteases
WO2003105772A2 (en) * 2002-06-13 2003-12-24 Beth Israel Deaconess Medical Center, Inc. Analogs of parathyroid hormone and pth-related protein as bone anabolic agents
US7635477B2 (en) * 2002-07-25 2009-12-22 The General Hospital Corporation Parathyroid hormone receptor activation and stem and progenitor cell expansion
AU2003256839B2 (en) * 2002-07-25 2009-10-29 The General Hospital Corporation Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion
AU2002951372A0 (en) * 2002-09-13 2002-09-26 St Vincent's Institute Of Medical Research Parathyroid hormone-like polypeptides
US8088734B2 (en) * 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
JP2007533596A (ja) * 2003-07-15 2007-11-22 ナショナル・リサーチ・カウンシル・オブ・カナダ 異常増殖性皮膚細胞を特徴とする状態の処置のためのヒト副甲状腺ホルモンの環状アナログ
EP1557176A1 (en) * 2004-01-26 2005-07-27 Ferring B.V. Treatment of bone metastases by means of PTH receptor agonists
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US20060046969A1 (en) * 2004-08-25 2006-03-02 Aegis Therapeutics Llc Antibacterial compositions for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
US20090047347A1 (en) * 2005-07-29 2009-02-19 Aegis Therapeutics, Inc. Compositions for Drug Administration
US8642564B2 (en) * 2004-08-25 2014-02-04 Aegis Therapeutics, Llc Compositions for drug administration
US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
US9114069B2 (en) * 2004-08-25 2015-08-25 Aegis Therapeutics, Llc Antibacterial compositions for drug administration
US20060046962A1 (en) * 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
EP1933863A4 (en) * 2005-09-06 2010-06-09 Zelos Therapeutics Inc PARATHYROIDIAN HORMONE ANALOGS AND METHODS USING SAME
US20110046059A1 (en) * 2005-09-06 2011-02-24 Zelos Therapeutics, Inc. Pharmaceutically acceptable formulations/compositions for peptidyl drugs
WO2007059470A2 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
WO2007133580A2 (en) * 2006-05-09 2007-11-22 Zelos Therapeutics, Inc. Use of pth (1-31) and optionally g-csf for hematopoietic stimulation
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
JP2010501476A (ja) * 2006-07-31 2010-01-21 ゼロス セラピューティクス, インコーポレイテッド 副甲状腺ホルモン類似体およびその使用方法
SI2084183T1 (sl) * 2006-10-13 2010-09-30 Lilly Co Eli Pegilirani pth kot modulatorji pth receptorja in njihove uporabe
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
EP2271347B1 (en) 2008-03-28 2016-05-11 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
US8440631B2 (en) 2008-12-22 2013-05-14 Aegis Therapeutics, Llc Compositions for drug administration
US8563513B2 (en) 2009-03-27 2013-10-22 Van Andel Research Institute Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
JP2013512688A (ja) 2009-12-07 2013-04-18 ミシガン テクノロジカル ユニバーシティ クロクマの副甲状腺ホルモン及びクロクマの副甲状腺ホルモンを使用する方法
ES2917973T3 (es) 2011-06-14 2022-07-12 Neurelis Inc Administración de benzodiacepina
AU2016256470B2 (en) 2015-04-29 2020-10-15 Radius Pharmaceuticals, Inc. Methods of treating cancer
CN105440126B (zh) * 2015-12-31 2019-10-25 南京工业大学 治疗骨质疏松的α-螺旋多肽及其制备方法与应用
LT3565542T (lt) 2017-01-05 2024-07-10 Radius Pharmaceuticals, Inc. Polimorfinės rad1901-2hcl formos
CN112423844B (zh) 2018-07-04 2024-08-13 雷迪厄斯制药公司 Rad1901-2hcl的多晶型形式

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2126299C (en) * 1994-06-20 2000-12-12 Gordon E. Willick Parathyroid hormone analogues for the treatment of osteoporosis
US6110892A (en) * 1994-06-20 2000-08-29 National Research Council Of Canada Parathyroid hormone analogues for the treatment of osteoporosis
DE19508672A1 (de) 1995-03-10 1996-09-12 Boehringer Mannheim Gmbh Neue cyclische Parathormonfragmente, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5717062A (en) * 1995-06-07 1998-02-10 Beth Israel Hospital Association Cyclic analogs of PTH and PTHrP
WO1998005683A1 (en) 1996-08-02 1998-02-12 National Research Council Of Canada Parathyroid hormone analogues for the treatment of osteoporosis
IL132901A0 (en) 1997-05-14 2001-03-19 Aventis Pharm Prod Inc Peptide parathyroid hormone analogs

Also Published As

Publication number Publication date
IL148654A0 (en) 2002-09-12
ZA200202162B (en) 2003-08-27
BR0016306A (pt) 2003-04-08
AU7398000A (en) 2001-04-24
CA2384341A1 (en) 2001-03-29
US6316410B1 (en) 2001-11-13
WO2001021643A3 (en) 2001-10-25
CN1377371A (zh) 2002-10-30
EP1214348A2 (en) 2002-06-19
EP1881006A1 (en) 2008-01-23
WO2001021643A2 (en) 2001-03-29
CZ20021026A3 (cs) 2003-05-14
JP2003510256A (ja) 2003-03-18
MXPA02002977A (es) 2004-09-06
JP4620309B2 (ja) 2011-01-26

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