SK3952002A3 - Manufacture and use of an antibiotic(s) preparation - Google Patents
Manufacture and use of an antibiotic(s) preparation Download PDFInfo
- Publication number
- SK3952002A3 SK3952002A3 SK395-2002A SK3952002A SK3952002A3 SK 3952002 A3 SK3952002 A3 SK 3952002A3 SK 3952002 A SK3952002 A SK 3952002A SK 3952002 A3 SK3952002 A3 SK 3952002A3
- Authority
- SK
- Slovakia
- Prior art keywords
- antibiotic
- resorbable
- preparation
- antibiotics
- acid
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title claims description 101
- 239000003242 anti bacterial agent Substances 0.000 title claims description 51
- 238000002360 preparation method Methods 0.000 title claims description 34
- 238000004519 manufacturing process Methods 0.000 title claims description 12
- -1 alkyl sulphate Chemical compound 0.000 claims description 63
- 150000003839 salts Chemical class 0.000 claims description 43
- 229940088710 antibiotic agent Drugs 0.000 claims description 35
- 239000002253 acid Substances 0.000 claims description 33
- 239000000203 mixture Substances 0.000 claims description 30
- 239000007943 implant Substances 0.000 claims description 20
- 238000000034 method Methods 0.000 claims description 11
- 239000000919 ceramic Substances 0.000 claims description 10
- 239000002647 aminoglycoside antibiotic agent Substances 0.000 claims description 9
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10114245A DE10114245A1 (de) | 2001-03-22 | 2001-03-22 | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK3952002A3 true SK3952002A3 (en) | 2002-10-08 |
Family
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Family Applications (1)
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| SK395-2002A SK3952002A3 (en) | 2001-03-22 | 2002-03-19 | Manufacture and use of an antibiotic(s) preparation |
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| EP (1) | EP1243258B1 (uk) |
| JP (1) | JP2002275098A (uk) |
| CN (1) | CN1286467C (uk) |
| AT (1) | ATE259636T1 (uk) |
| AU (1) | AU772160B2 (uk) |
| BG (1) | BG65505B1 (uk) |
| BR (1) | BR0201099A (uk) |
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| DK (1) | DK1243258T3 (uk) |
| EE (1) | EE200200155A (uk) |
| ES (1) | ES2213718T3 (uk) |
| GE (1) | GEP20053450B (uk) |
| HR (1) | HRP20020242B1 (uk) |
| HU (1) | HUP0201043A2 (uk) |
| IL (1) | IL148705A (uk) |
| IS (1) | IS2499B (uk) |
| MD (1) | MD2353C2 (uk) |
| MX (1) | MXPA02003006A (uk) |
| NO (1) | NO20021389L (uk) |
| NZ (1) | NZ517920A (uk) |
| PL (1) | PL204985B1 (uk) |
| PT (1) | PT1243258E (uk) |
| RU (1) | RU2212880C1 (uk) |
| SA (1) | SA02230036B1 (uk) |
| SK (1) | SK3952002A3 (uk) |
| TR (1) | TR200400363T4 (uk) |
| UA (1) | UA71993C2 (uk) |
| YU (1) | YU11702A (uk) |
| ZA (1) | ZA200202255B (uk) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IS6389A (is) | 2001-08-31 | 2003-03-03 | Heraeus Kulzer Gmbh & Co. Kg | Reynsla af sýklalyfjahúðun skrokka, sem í eru örholrými, og einnig af þannig húðuðum skrokkum og notkun þeirra |
| IS6390A (is) | 2001-08-31 | 2003-03-03 | Heraeus Kulzer Gmbh & Co. Kg | Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra |
| DE10227935B4 (de) * | 2002-06-21 | 2007-10-04 | Heraeus Kulzer Gmbh | Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung |
| DE10318991A1 (de) * | 2003-04-25 | 2004-11-18 | Heraeus Kulzer Gmbh & Co. Kg | Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung |
| ZA200604869B (en) | 2003-12-04 | 2007-11-28 | Univ Utah Res Found | Modified macromolecules and methods of making and using thereof |
| DE102004060666B3 (de) | 2004-12-15 | 2006-03-30 | Heraeus Kulzer Gmbh | Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung |
| DE102005002703C5 (de) | 2005-01-19 | 2013-07-04 | Heraeus Kulzer Gmbh | Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung |
| US8685421B2 (en) | 2006-07-07 | 2014-04-01 | Surmodics, Inc. | Beaded wound spacer device |
| SI2007367T1 (sl) * | 2007-02-16 | 2011-04-29 | Alpharma Llc | Krmni premiks z zdravilnim učinkom, ki vsebuje klortetraciklin hidroklorid |
| DE102007063613B4 (de) * | 2007-04-24 | 2010-01-07 | Heraeus Kulzer Gmbh | Verwendung eines Spacer-Polymethylmethacrylat-Knochenzement |
| DE102007039871A1 (de) | 2007-08-21 | 2009-02-26 | Friedrich-Baur-Gmbh | Weichgewebe-Implantat mit antibakterieller Wirkung |
| CN101225125B (zh) * | 2008-01-18 | 2012-12-05 | 中国科学院烟台海岸带研究所 | 一种吸湿保湿剂及其制备方法 |
| US8167836B2 (en) * | 2009-12-08 | 2012-05-01 | Taris Biomedical, Inc. | Tissue expander configured for drug delivery |
| DE102010020940B4 (de) * | 2010-05-19 | 2014-09-25 | Heraeus Medical Gmbh | Antibiotische Beschichtung |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| CN102391954B (zh) * | 2011-10-26 | 2014-12-10 | 厦门大学 | 球形棕囊藻培养液的除菌方法 |
| CN102552885A (zh) * | 2011-12-16 | 2012-07-11 | 青岛海芬海洋生物科技有限公司 | 海洋生物痔疮及肛内上皮和直肠粘膜上皮细胞消炎修护液 |
| JP6298468B2 (ja) | 2012-10-16 | 2018-03-20 | サーモディクス，インコーポレイテッド | 創傷充填デバイスおよび方法 |
| RU2540468C2 (ru) * | 2012-11-06 | 2015-02-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Нижегородский государственный университет им. Н.И. Лобачевского"Российская Федерация | Способ получения композиционных рассасывающихся материалов на основе хитозана и полилактида |
| EP2968880A1 (en) | 2013-03-15 | 2016-01-20 | TARIS Biomedical LLC | Drug delivery devices with drug-permeable component and methods |
| US10201457B2 (en) | 2014-08-01 | 2019-02-12 | Surmodics, Inc. | Wound packing device with nanotextured surface |
| WO2016172704A1 (en) | 2015-04-23 | 2016-10-27 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
| CN105999401B (zh) * | 2016-07-22 | 2019-03-08 | 武汉理工大学 | 一种基于羟基磷灰石的牙科抑菌修复材料及其制备方法 |
| CN107459654B (zh) * | 2017-08-03 | 2020-05-26 | 天津大学 | 一种模拟抗菌肽共聚物及其制备方法 |
| CN109674806B (zh) * | 2019-01-14 | 2021-10-26 | 福州奥尼多生物科技有限公司 | 春雷霉素在制备抗菌药物中的用途 |
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| US3091572A (en) * | 1962-07-16 | 1963-05-28 | Schering Corp | Gentamycin and method of production |
| ES322771A1 (es) * | 1966-02-08 | 1966-11-16 | Folch Vazquez Conrado | Procedimiento para la preparaciën de laurilsulfato de tetraciclina |
| ES315101A1 (es) * | 1965-07-08 | 1966-01-01 | Folch Vazquez Conrado | Procedimiento de preparaciën de nuevos derivados de tetraciclina |
| FR6476M (uk) * | 1967-06-06 | 1968-11-18 | ||
| DE2320373B2 (de) * | 1973-04-21 | 1978-04-06 | Merck Patent Gmbh, 6100 Darmstadt | Antibioticahaltiges Mittel und seine Verwendung als chirurgisches Kunststoffmaterial |
| FR2272680B1 (uk) * | 1974-05-29 | 1978-07-21 | Hosbon Sa Lab | |
| AR216922A1 (es) * | 1976-11-11 | 1980-02-15 | Merck Patent Gmbh | Procedimiento para la fabricacion de un medio quirurgico |
| DE2843963A1 (de) * | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
| DE3206725A1 (de) * | 1981-05-13 | 1982-12-02 | Merck Patent Gmbh, 6100 Darmstadt | Schwer loesliche salze von aminoglykosidantibiotika |
| DE3248328A1 (de) * | 1982-12-28 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe |
| US5035891A (en) * | 1987-10-05 | 1991-07-30 | Syntex (U.S.A.) Inc. | Controlled release subcutaneous implant |
| FR2668367B1 (fr) * | 1990-10-26 | 1994-05-13 | Centre Nal Recherc Scientifique | Medicament implantable a effet prolonge. |
| US5709875A (en) * | 1990-10-26 | 1998-01-20 | Centre National De La Rechierche Scientifique (C.N.R.S) | Implantable biodegradable material and process for its production |
| DE4404018A1 (de) * | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
| AU6439094A (en) * | 1994-04-06 | 1995-10-30 | Aktsionernoe Obschestvo Zakrytogo Tipa Firma "Assol" (Firma "Assol") | Pharmaceutical agent for local application and a method of obtaining same |
| US5614206A (en) * | 1995-03-07 | 1997-03-25 | Wright Medical Technology, Inc. | Controlled dissolution pellet containing calcium sulfate |
| US5783217A (en) * | 1995-11-07 | 1998-07-21 | Etex Corporation | Low temperature calcium phosphate apatite and a method of its manufacture |
| US5670142A (en) * | 1996-07-08 | 1997-09-23 | Donald Neudecker | Treatment for itch of chicken pox |
| US5874418A (en) * | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
| US5980928A (en) * | 1997-07-29 | 1999-11-09 | Terry; Paul B. | Implant for preventing conjunctivitis in cattle |
| US6428579B1 (en) * | 1998-07-01 | 2002-08-06 | Brown University Research Foundation | Implantable prosthetic devices coated with bioactive molecules |
| DE10114244A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung |
| DE10114364A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Verfahren zur Herstellung von antibiotischen Kompositen |
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2001
- 2001-03-22 DE DE10114245A patent/DE10114245A1/de not_active Ceased
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2002
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- 2002-02-15 IS IS6271A patent/IS2499B/is unknown
- 2002-02-19 GE GE4983A patent/GEP20053450B/en unknown
- 2002-02-20 YU YU11702A patent/YU11702A/sh unknown
- 2002-02-27 BG BG106456A patent/BG65505B1/bg unknown
- 2002-03-06 AT AT02005024T patent/ATE259636T1/de not_active IP Right Cessation
- 2002-03-06 DE DE50200244T patent/DE50200244D1/de not_active Expired - Lifetime
- 2002-03-06 EP EP02005024A patent/EP1243258B1/de not_active Expired - Lifetime
- 2002-03-06 TR TR2004/00363T patent/TR200400363T4/xx unknown
- 2002-03-06 PT PT02005024T patent/PT1243258E/pt unknown
- 2002-03-06 ES ES02005024T patent/ES2213718T3/es not_active Expired - Lifetime
- 2002-03-06 DK DK02005024T patent/DK1243258T3/da active
- 2002-03-08 CZ CZ2002868A patent/CZ2002868A3/cs unknown
- 2002-03-14 IL IL148705A patent/IL148705A/en not_active IP Right Cessation
- 2002-03-19 US US10/101,254 patent/US20020183265A1/en not_active Abandoned
- 2002-03-19 SK SK395-2002A patent/SK3952002A3/sk unknown
- 2002-03-19 JP JP2002076626A patent/JP2002275098A/ja active Pending
- 2002-03-20 ZA ZA200202255A patent/ZA200202255B/xx unknown
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- 2002-03-20 MX MXPA02003006A patent/MXPA02003006A/es active IP Right Grant
- 2002-03-21 HU HU0201043A patent/HUP0201043A2/hu unknown
- 2002-03-21 NZ NZ517920A patent/NZ517920A/xx unknown
- 2002-03-21 AU AU27562/02A patent/AU772160B2/en not_active Ceased
- 2002-03-21 UA UA2002032264A patent/UA71993C2/uk unknown
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- 2002-03-21 RU RU2002107210/14A patent/RU2212880C1/ru active
- 2002-03-21 PL PL352922A patent/PL204985B1/pl not_active IP Right Cessation
- 2002-03-22 BR BR0201099-2A patent/BR0201099A/pt not_active IP Right Cessation
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- 2002-04-02 SA SA02230036A patent/SA02230036B1/ar unknown
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