SK285212B6 - Použitie 4alfa-acetoxy-2alfa-benzoyloxy-5beta, 20-epoxy-1beta- hydroxy-7beta, 10beta-dimetoxy-9-oxo-11-taxen-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenyl-propionátu - Google Patents

Použitie 4alfa-acetoxy-2alfa-benzoyloxy-5beta, 20-epoxy-1beta- hydroxy-7beta, 10beta-dimetoxy-9-oxo-11-taxen-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenyl-propionátu Download PDF

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Publication number
SK285212B6
SK285212B6 SK230-2001A SK2302001A SK285212B6 SK 285212 B6 SK285212 B6 SK 285212B6 SK 2302001 A SK2302001 A SK 2302001A SK 285212 B6 SK285212 B6 SK 285212B6
Authority
SK
Slovakia
Prior art keywords
hydroxy
compound
brain
treatment
tert
Prior art date
Application number
SK230-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK2302001A3 (en
Inventor
Marie-Christine Bissery
Patricia Vrignaud
Simon Roberts
Clive Brealey
Original Assignee
Aventis Pharma S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98115401A external-priority patent/EP0982027A1/en
Application filed by Aventis Pharma S. A. filed Critical Aventis Pharma S. A.
Publication of SK2302001A3 publication Critical patent/SK2302001A3/sk
Publication of SK285212B6 publication Critical patent/SK285212B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK230-2001A 1998-08-17 1999-08-13 Použitie 4alfa-acetoxy-2alfa-benzoyloxy-5beta, 20-epoxy-1beta- hydroxy-7beta, 10beta-dimetoxy-9-oxo-11-taxen-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenyl-propionátu SK285212B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98115401A EP0982027A1 (en) 1998-08-17 1998-08-17 Taxoid derivatives for treating abnormal cell proliferation of the brain
US9958198P 1998-09-08 1998-09-08
PCT/EP1999/006291 WO2000009120A1 (en) 1998-08-17 1999-08-13 New use of taxoid derivatives

Publications (2)

Publication Number Publication Date
SK2302001A3 SK2302001A3 (en) 2001-09-11
SK285212B6 true SK285212B6 (sk) 2006-09-07

Family

ID=26149540

Family Applications (1)

Application Number Title Priority Date Filing Date
SK230-2001A SK285212B6 (sk) 1998-08-17 1999-08-13 Použitie 4alfa-acetoxy-2alfa-benzoyloxy-5beta, 20-epoxy-1beta- hydroxy-7beta, 10beta-dimetoxy-9-oxo-11-taxen-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenyl-propionátu

Country Status (19)

Country Link
US (1) US6346543B1 (ko)
EP (1) EP1109547A1 (ko)
JP (1) JP5354762B2 (ko)
KR (1) KR100710533B1 (ko)
AU (1) AU766168B2 (ko)
BG (1) BG65365B1 (ko)
CA (1) CA2340921C (ko)
CZ (1) CZ293959B6 (ko)
EE (1) EE04903B1 (ko)
HU (1) HU230235B1 (ko)
ID (1) ID27545A (ko)
IL (1) IL141238A0 (ko)
ME (1) ME00533B (ko)
NO (1) NO327296B1 (ko)
NZ (1) NZ509965A (ko)
RS (1) RS52011B (ko)
SK (1) SK285212B6 (ko)
TR (1) TR200100557T2 (ko)
WO (1) WO2000009120A1 (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
EP1020188A1 (en) * 1999-01-13 2000-07-19 Aventis Pharma S.A. New use of taxoid derivatives
US20040010134A1 (en) * 2000-04-12 2004-01-15 Rosen Craig A. Albumin fusion proteins
WO2002097038A2 (en) * 2001-05-25 2002-12-05 Human Genome Sciences, Inc. Chemokine beta-1 fusion proteins
WO2003059934A2 (en) * 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin fusion proteins
DK1463751T3 (da) * 2001-12-21 2013-08-26 Human Genome Sciences Inc Albuminfusionsproteiner.
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
EP2331140B1 (en) 2008-08-11 2018-07-04 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
EA024186B1 (ru) 2009-10-29 2016-08-31 Авентис Фарма С.А. Применение кабазитаксела в комбинации с преднизоном или преднизолоном для лечения рака простаты
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
US20130331443A1 (en) 2010-12-22 2013-12-12 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
JP6025861B2 (ja) 2011-12-13 2016-11-16 アベンティス・ファーマ・ソシエテ・アノニム カバジタキセルの結晶形およびこれを調製するための方法
SG11201404712UA (en) * 2012-02-10 2014-09-26 Aventis Pharma Sa New pediatric uses of cabazitaxel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2696459B1 (fr) 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
TW467896B (en) 1993-03-19 2001-12-11 Bristol Myers Squibb Co Novel β-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes
MA23823A1 (fr) * 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
US5847170A (en) * 1995-03-27 1998-12-08 Rhone-Poulenc Rorer, S.A. Taxoids, their preparation and pharmaceutical compositions containing them
US5481018A (en) 1995-03-31 1996-01-02 The Dow Chemical Company Amino nitrile intermediate for the preparation of alanine diacetic acid
FR2771092B1 (fr) 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides

Also Published As

Publication number Publication date
ME00533B (me) 2011-10-10
BG105264A (en) 2001-11-30
AU766168B2 (en) 2003-10-09
JP5354762B2 (ja) 2013-11-27
CZ293959B6 (cs) 2004-08-18
RS52011B (sr) 2012-04-30
EE200100079A (et) 2002-08-15
CA2340921A1 (en) 2000-02-24
BG65365B1 (bg) 2008-04-30
ID27545A (id) 2001-04-12
HUP0103748A3 (en) 2003-01-28
IL141238A0 (en) 2002-03-10
CZ2001604A3 (en) 2001-06-13
NO327296B1 (no) 2009-06-02
TR200100557T2 (tr) 2001-07-23
US6346543B1 (en) 2002-02-12
HU230235B1 (hu) 2015-10-28
NO20010654D0 (no) 2001-02-07
YU7901A (sh) 2003-12-31
KR100710533B1 (ko) 2007-04-23
AU5741999A (en) 2000-03-06
EP1109547A1 (en) 2001-06-27
HUP0103748A2 (hu) 2002-04-29
WO2000009120A1 (en) 2000-02-24
CA2340921C (en) 2009-01-06
EE04903B1 (et) 2007-10-15
NZ509965A (en) 2003-09-26
SK2302001A3 (en) 2001-09-11
KR20010085396A (ko) 2001-09-07
JP2002522490A (ja) 2002-07-23
WO2000009120A8 (en) 2001-04-05
NO20010654L (no) 2001-02-07

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MK4A Expiry of patent

Expiry date: 20190813