SK284879B6 - Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie - Google Patents

Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie Download PDF

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Publication number
SK284879B6
SK284879B6 SK1761-98A SK176198A SK284879B6 SK 284879 B6 SK284879 B6 SK 284879B6 SK 176198 A SK176198 A SK 176198A SK 284879 B6 SK284879 B6 SK 284879B6
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Slovakia
Prior art keywords
ser
gly
thr
leu
ala
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SK1761-98A
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English (en)
Slovak (sk)
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SK176198A3 (en
Inventor
Sylvia Miescher
Monique Vogel
Beda Stadler
Andreas Morell
Martin Imboden
Hanspeter Amstutz
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Zlb Behring Ag
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Application filed by Zlb Behring Ag filed Critical Zlb Behring Ag
Publication of SK176198A3 publication Critical patent/SK176198A3/sk
Publication of SK284879B6 publication Critical patent/SK284879B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/80—Antibody or fragment thereof whose amino acid sequence is disclosed in whole or in part
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
SK1761-98A 1996-06-24 1997-06-20 Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie SK284879B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96810421 1996-06-24
PCT/EP1997/003253 WO1997049809A1 (fr) 1996-06-24 1997-06-20 Olypeptides capables de former des structures de liaison a l'ant igene avec une specificite pour les antigenes de rhesus d, adn les codant et procede pour leur preparation et leur utilisation

Publications (2)

Publication Number Publication Date
SK176198A3 SK176198A3 (en) 1999-07-12
SK284879B6 true SK284879B6 (sk) 2006-01-05

Family

ID=8225636

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1761-98A SK284879B6 (sk) 1996-06-24 1997-06-20 Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie

Country Status (23)

Country Link
US (3) US7038020B1 (fr)
EP (1) EP0920509B1 (fr)
JP (1) JP3841360B2 (fr)
KR (1) KR100361449B1 (fr)
AT (1) ATE272116T1 (fr)
AU (1) AU722127B2 (fr)
BG (1) BG64534B1 (fr)
BR (1) BR9709958A (fr)
CA (1) CA2258494C (fr)
CZ (1) CZ296807B6 (fr)
DE (1) DE69730031T2 (fr)
DK (1) DK0920509T3 (fr)
ES (1) ES2224255T3 (fr)
HU (1) HUP9902605A3 (fr)
IL (1) IL127595A (fr)
IS (1) IS2220B (fr)
NO (1) NO327947B1 (fr)
NZ (1) NZ333329A (fr)
PL (1) PL186019B1 (fr)
RU (1) RU2204602C2 (fr)
SK (1) SK284879B6 (fr)
TR (1) TR199802692T2 (fr)
WO (1) WO1997049809A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1131428A2 (fr) * 1998-11-19 2001-09-12 Incyte Pharmaceuticals, Inc. Proteines de la superfamille des immunoglobulines
EP1106625A1 (fr) * 1999-11-17 2001-06-13 ZLB Bioplasma AG Séquences péptidiques spécifiques pour rhesus D
FR2807767B1 (fr) * 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
AU2001253589B2 (en) * 2000-04-17 2007-08-16 Dyax Corp Methods of constructing display libraries of genetic packages for members of a diverse family of peptides
AU2002226049A1 (en) * 2000-12-05 2002-06-18 Alexion Pharmaceuticals, Inc. Engineered plasmids and their use for in situ production of genes
US20030119056A1 (en) 2000-12-18 2003-06-26 Ladner Robert Charles Focused libraries of genetic packages
AU2016225923B2 (en) * 2001-04-17 2018-07-05 Takeda Pharmaceutical Company Limited Novel Methods of Constructing Libraries Comprising Displayed and/or Expressed Members of a Diverse Family of Peptides, Polypeptides or Proteins and the Novel Libraries
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
RU2426795C2 (ru) 2004-07-20 2011-08-20 Симфоген А/С Способ структурной характеристики рекомбинантного поликлонального белка или поликлональной клеточной линии
CA2574062A1 (fr) * 2004-07-20 2006-01-26 Symphogen A/S Anticorps polyclonal recombine anti-rhesus d et procedes de production
GB0706558D0 (en) * 2007-04-03 2007-05-09 Common Services Agency For The Diagnostic assay
BRPI0816785A2 (pt) 2007-09-14 2017-05-02 Adimab Inc bibliotecas de anticorpos sintéticos racionalmente desenhadas, e, usos para as mesmas
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US20090093004A1 (en) 2007-10-04 2009-04-09 Symphogen A/S Potency assay
US9873957B2 (en) 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
CA2968164C (fr) 2008-04-24 2019-08-20 Dyax Corp. Bibliotheques de materiels genetiques comprenant de nouvelles conceptions cdr1, cdr2 et cdr3 hc et de nouvelles conceptions cdr1, cdr2 et cdr3 lc
KR102024922B1 (ko) 2010-07-16 2019-09-25 아디맵 엘엘씨 항체 라이브러리
EP2917236A2 (fr) * 2012-11-06 2015-09-16 MedImmune, LLC Polythérapies à l'aide de molécules de liaison anti-pseudomonas psl et pcrv
WO2019075523A1 (fr) * 2017-10-20 2019-04-25 Csl Ltd. Procédé

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2127434A (en) 1982-09-17 1984-04-11 Univ London A human monoclonal antibody against Rhesus D antigen
GB8925590D0 (en) 1989-11-13 1990-01-04 Central Blood Lab Authority Monoclonal antibodies

Also Published As

Publication number Publication date
ATE272116T1 (de) 2004-08-15
BG103016A (en) 1999-08-31
AU3342397A (en) 1998-01-14
DK0920509T3 (da) 2004-12-06
NO327947B1 (no) 2009-10-26
IL127595A (en) 2005-09-25
BR9709958A (pt) 1999-08-10
IS4922A (is) 1998-12-11
IL127595A0 (en) 1999-10-28
HUP9902605A2 (hu) 1999-11-29
EP0920509A1 (fr) 1999-06-09
CZ296807B6 (cs) 2006-06-14
KR100361449B1 (ko) 2003-01-24
JP2000515732A (ja) 2000-11-28
PL186019B1 (pl) 2003-09-30
US20060165694A1 (en) 2006-07-27
NO986088D0 (no) 1998-12-23
PL330794A1 (en) 1999-06-07
EP0920509B1 (fr) 2004-07-28
HUP9902605A3 (en) 2001-11-28
RU2204602C2 (ru) 2003-05-20
ES2224255T3 (es) 2005-03-01
CA2258494C (fr) 2008-05-27
IS2220B (is) 2007-03-15
US7038020B1 (en) 2006-05-02
NZ333329A (en) 2000-07-28
KR20000022530A (ko) 2000-04-25
WO1997049809A1 (fr) 1997-12-31
TR199802692T2 (xx) 1999-03-22
DE69730031T2 (de) 2005-06-16
AU722127B2 (en) 2000-07-20
BG64534B1 (bg) 2005-06-30
US7429647B2 (en) 2008-09-30
US20050266013A1 (en) 2005-12-01
US7399471B2 (en) 2008-07-15
CZ395998A3 (cs) 1999-05-12
JP3841360B2 (ja) 2006-11-01
CA2258494A1 (fr) 1997-12-31
DE69730031D1 (de) 2004-09-02
NO986088L (no) 1999-02-24
SK176198A3 (en) 1999-07-12

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20120620