SK284538B6 - Progesterónantagonisticky a antiestrogénne účinné zlúčeniny na spoločné použitie na výrobu ženskej antikoncepcie - Google Patents

Progesterónantagonisticky a antiestrogénne účinné zlúčeniny na spoločné použitie na výrobu ženskej antikoncepcie Download PDF

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Publication number
SK284538B6
SK284538B6 SK789-97A SK78997A SK284538B6 SK 284538 B6 SK284538 B6 SK 284538B6 SK 78997 A SK78997 A SK 78997A SK 284538 B6 SK284538 B6 SK 284538B6
Authority
SK
Slovakia
Prior art keywords
hydroxy
phenyl
estra
compound
dien
Prior art date
Application number
SK789-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK78997A3 (en
Inventor
Kristof Chwalisz
Klaus St�Ckemann
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of SK78997A3 publication Critical patent/SK78997A3/sk
Publication of SK284538B6 publication Critical patent/SK284538B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SK789-97A 1994-12-23 1995-12-23 Progesterónantagonisticky a antiestrogénne účinné zlúčeniny na spoločné použitie na výrobu ženskej antikoncepcie SK284538B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4447402 1994-12-23
PCT/EP1995/005106 WO1996019997A1 (de) 1994-12-23 1995-12-23 Progesteronantagonistisch- und antiöstrogen wirksame verbindungen zur gemeinsamen verwendung für die weibliche kontrazeption

Publications (2)

Publication Number Publication Date
SK78997A3 SK78997A3 (en) 1998-01-14
SK284538B6 true SK284538B6 (sk) 2005-06-02

Family

ID=6537602

Family Applications (1)

Application Number Title Priority Date Filing Date
SK789-97A SK284538B6 (sk) 1994-12-23 1995-12-23 Progesterónantagonisticky a antiestrogénne účinné zlúčeniny na spoločné použitie na výrobu ženskej antikoncepcie

Country Status (24)

Country Link
US (1) US6362237B1 (de)
EP (1) EP0799042A1 (de)
JP (1) JPH10511378A (de)
KR (1) KR100385663B1 (de)
CN (1) CN1075375C (de)
AU (1) AU710819B2 (de)
BG (1) BG62384B1 (de)
BR (1) BR9510550A (de)
CA (1) CA2208321A1 (de)
CZ (1) CZ288062B6 (de)
EE (1) EE03421B1 (de)
FI (1) FI972623A (de)
HU (1) HUT77519A (de)
IL (1) IL116505A0 (de)
LT (1) LT4291B (de)
LV (1) LV11883B (de)
NO (1) NO314066B1 (de)
NZ (1) NZ298769A (de)
PL (1) PL183843B1 (de)
RO (1) RO121086B1 (de)
SI (1) SI9520136A (de)
SK (1) SK284538B6 (de)
WO (1) WO1996019997A1 (de)
ZA (1) ZA9510926B (de)

Families Citing this family (28)

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DE19652408C2 (de) * 1996-12-06 2002-04-18 Schering Ag Steroidester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneimitteln
DE19745085A1 (de) * 1997-10-11 1999-04-15 Jenapharm Gmbh 11ß-Benzaldoxim-9alpha,10alpha-epoxy-estr-4-en-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
US6326392B1 (en) 1997-11-06 2001-12-04 American Home Products Corporation Anti-estrogen plus progestin containing oral contraceptives
ID24568A (id) * 1997-11-06 2000-07-27 American Home Prod Kontrasepsi oral yang mengandung anti-estrogen plus progestin
DE19809845A1 (de) 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
US6369056B1 (en) 1999-05-04 2002-04-09 American Home Products Corporation Cyclic urea and cyclic amide derivatives
US6306851B1 (en) 1999-05-04 2001-10-23 American Home Products Corporation Cyclocarbamate and cyclic amide derivatives
US6380178B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Cyclic regimens using cyclocarbamate and cyclic amide derivatives
US6339098B1 (en) 1999-05-04 2002-01-15 American Home Products Corporation 2,1-benzisothiazoline 2,2-dioxides
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
US6329416B1 (en) 1999-05-04 2001-12-11 American Home Products Corporation Combination regimens using 3,3-substituted indoline derivatives
US6399593B1 (en) 1999-05-04 2002-06-04 Wyeth Cyclic regimens using cyclic urea and cyclic amide derivatives
US6498154B1 (en) 1999-05-04 2002-12-24 Wyeth Cyclic regimens using quinazolinone and benzoxazine derivatives
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6319912B1 (en) 1999-05-04 2001-11-20 American Home Products Corporation Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6380235B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Benzimidazolones and analogues
US6417214B1 (en) 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
US6462032B1 (en) 1999-05-04 2002-10-08 Wyeth Cyclic regimens utilizing indoline derivatives
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6423699B1 (en) 1999-05-04 2002-07-23 American Home Products Corporation Combination therapies using benzimidazolones
US6444668B1 (en) 1999-05-04 2002-09-03 Wyeth Combination regimens using progesterone receptor modulators
US6358947B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Tetracyclic progesterone receptor modulator compounds and methods
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
JP4382735B2 (ja) 2005-10-06 2009-12-16 独立行政法人科学技術振興機構 神経因性疼痛治療剤
EP2234491A4 (de) * 2007-12-20 2010-12-22 Teva Womens Health Inc Dosierungsschemata und pharmazeutische zusammensetzungen und packungen für die notfallkontrazeption

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2824733C2 (de) 1978-06-06 1984-03-15 Heidelberger Druckmaschinen Ag, 6900 Heidelberg Umführtrommel für Schön- und Widerdruckmaschinen
ZA8231B (en) 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
IL68222A (en) * 1983-03-24 1987-02-27 Yeda Res & Dev Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity
ES8502612A1 (es) 1983-06-15 1985-02-01 Schering Ag Procedimiento para la preparacion de 13a-alquilgonanos
DE3322285A1 (de) 1983-06-18 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen 1-alkyl-androsta-1,4-dien-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3337450A1 (de) 1983-10-12 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandine und antigestagene fuer den schwangerschaftsabbruch
AU580843B2 (en) 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
DE3533175A1 (de) 1985-09-13 1987-03-19 Schering Ag Antigestagene zur verschiebung der endometrialen reifung
IE60780B1 (en) 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE3708942A1 (de) 1987-03-18 1988-09-29 Schering Ag 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3866410D1 (de) 1987-04-24 1992-01-09 Akzo Nv 11-arylestranderivate und 11-arylpregnanderivate.
DE3733478A1 (de) 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
EP0310542B1 (de) * 1987-10-01 1994-06-08 Schering Aktiengesellschaft Antigestagen- und antiöstrogenwirksame Verbindungen zur Behandlung hormonabhängiger Tumoren
ES2053714T3 (es) 1987-12-12 1994-08-01 Akzo Nv Proceso para la preparacion de 11-arilesteroides.
GB8813353D0 (en) * 1988-06-06 1988-07-13 Ici Plc Therapeutic product
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
DE3926365A1 (de) 1989-08-04 1991-02-07 Schering Ag Cycloalkylenazole, verfahren zu deren herstellung, pharmazeutische praeparate, die diese enthalten sowie ihre verwendung zur herstellung von arzneimitteln
CH683151A5 (de) 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
MX9302312A (es) 1992-04-21 1994-06-30 Ligand Pharm Inc Compuestos agonistas y antagonistas receptores de la progesterona, no esteroides y composiciones farmaceuticas que los contienen.
US5439913A (en) 1992-05-12 1995-08-08 Schering Aktiengesellschaft Contraception method using competitive progesterone antagonists and novel compounds useful therein

Also Published As

Publication number Publication date
SK78997A3 (en) 1998-01-14
PL183843B1 (pl) 2002-07-31
BR9510550A (pt) 1998-06-16
CZ288062B6 (cs) 2001-04-11
AU4433796A (en) 1996-07-19
CA2208321A1 (en) 1996-07-04
ZA9510926B (en) 1996-07-03
LV11883A (lv) 1997-12-20
NZ298769A (en) 2000-09-29
PL320786A1 (en) 1997-10-27
NO972877L (no) 1997-08-22
FI972623A0 (fi) 1997-06-18
LT97107A (en) 1997-10-27
NO314066B1 (no) 2003-01-27
LV11883B (lv) 1998-05-20
CN1075375C (zh) 2001-11-28
IL116505A0 (en) 1996-03-31
BG101553A (en) 1998-09-30
BG62384B1 (bg) 1999-10-29
JPH10511378A (ja) 1998-11-04
CN1171051A (zh) 1998-01-21
EE03421B1 (et) 2001-06-15
AU710819B2 (en) 1999-09-30
EP0799042A1 (de) 1997-10-08
HUT77519A (hu) 1998-05-28
LT4291B (lt) 1998-02-25
NO972877D0 (no) 1997-06-20
SI9520136A (en) 1997-12-31
KR100385663B1 (ko) 2003-08-19
RO121086B1 (ro) 2006-12-29
KR980700866A (ko) 1998-04-30
CZ195397A3 (en) 1997-11-12
EE9700143A (et) 1997-12-15
FI972623A (fi) 1997-06-18
MX9704742A (es) 1997-10-31
US6362237B1 (en) 2002-03-26
WO1996019997A1 (de) 1996-07-04

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