SK284442B6 - Použitie steroidných antagonistov estrogénových receptorov na antikoncepciu pre mužov - Google Patents
Použitie steroidných antagonistov estrogénových receptorov na antikoncepciu pre mužov Download PDFInfo
- Publication number
- SK284442B6 SK284442B6 SK1238-97A SK123897A SK284442B6 SK 284442 B6 SK284442 B6 SK 284442B6 SK 123897 A SK123897 A SK 123897A SK 284442 B6 SK284442 B6 SK 284442B6
- Authority
- SK
- Slovakia
- Prior art keywords
- estrogen receptor
- tablet
- receptor antagonists
- antiestrogens
- male
- Prior art date
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- 229940102550 Estrogen receptor antagonist Drugs 0.000 title claims abstract description 15
- 230000003637 steroidlike Effects 0.000 title claims description 7
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- 230000001833 anti-estrogenic effect Effects 0.000 claims abstract description 35
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- 238000004519 manufacturing process Methods 0.000 claims abstract description 9
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- 229960001603 tamoxifen Drugs 0.000 claims description 10
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- -1 4,4,5,5,5-pentafluoropentylsulfinyl Chemical group 0.000 claims description 7
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- 241000557626 Corvus corax Species 0.000 description 1
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- XLXSAKCOAKORKW-UHFFFAOYSA-N gonadorelin Chemical class C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 XLXSAKCOAKORKW-UHFFFAOYSA-N 0.000 description 1
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- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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- GZUITABIAKMVPG-UHFFFAOYSA-N raloxifene Chemical compound C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 GZUITABIAKMVPG-UHFFFAOYSA-N 0.000 description 1
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- 230000009885 systemic effect Effects 0.000 description 1
- 229960005353 testolactone Drugs 0.000 description 1
- BPEWUONYVDABNZ-DZBHQSCQSA-N testolactone Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(OC(=O)CC4)[C@@H]4[C@@H]3CCC2=C1 BPEWUONYVDABNZ-DZBHQSCQSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Steroid Compounds (AREA)
- Materials For Medical Uses (AREA)
- Junction Field-Effect Transistors (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19510862A DE19510862A1 (de) | 1995-03-16 | 1995-03-16 | Verwendung von Antiestrogenen zur männlichen Fertilitätskontrolle |
| PCT/EP1996/001191 WO1996028154A2 (de) | 1995-03-16 | 1996-03-15 | Verwendung von antiestrogenen zur männlichen fertilitätskontrolle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK123897A3 SK123897A3 (en) | 1998-02-04 |
| SK284442B6 true SK284442B6 (sk) | 2005-04-01 |
Family
ID=7757669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1238-97A SK284442B6 (sk) | 1995-03-16 | 1996-03-15 | Použitie steroidných antagonistov estrogénových receptorov na antikoncepciu pre mužov |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20010056086A1 (cs) |
| EP (1) | EP0814803B1 (cs) |
| JP (1) | JPH11501648A (cs) |
| KR (1) | KR19980703057A (cs) |
| CN (1) | CN1151792C (cs) |
| AT (1) | ATE342055T1 (cs) |
| CA (1) | CA2215373A1 (cs) |
| CZ (1) | CZ293771B6 (cs) |
| DE (2) | DE19510862A1 (cs) |
| DK (1) | DK0814803T3 (cs) |
| ES (1) | ES2275273T3 (cs) |
| HU (1) | HUP9900313A3 (cs) |
| IL (1) | IL117515A (cs) |
| NO (1) | NO974256L (cs) |
| NZ (1) | NZ303672A (cs) |
| PL (1) | PL186085B1 (cs) |
| PT (1) | PT814803E (cs) |
| SK (1) | SK284442B6 (cs) |
| TW (1) | TW503106B (cs) |
| WO (1) | WO1996028154A2 (cs) |
| ZA (1) | ZA962176B (cs) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4344462C2 (de) | 1993-12-22 | 1996-02-01 | Schering Ag | Zusammensetzung für die Empfängnisverhütung |
| DE10159217A1 (de) | 2001-11-27 | 2003-06-05 | Schering Ag | 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate |
| EP2258375A1 (de) | 2009-06-04 | 2010-12-08 | Bayer Schering Pharma Aktiengesellschaft | 17B-alkyl-17alpha-oxy-estratriene |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3213328A1 (de) * | 1982-04-06 | 1983-10-06 | Schering Ag | 3,4,17-trioxygenierte 4,9(11)-androstadiene |
| GB8813353D0 (en) * | 1988-06-06 | 1988-07-13 | Ici Plc | Therapeutic product |
| US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
| US5166201A (en) * | 1990-11-30 | 1992-11-24 | Merrell Dow Pharmaceuticals Inc. | 2β,19-ethylene bridged steroids as aromatase inhibitors |
| FR2685332A1 (fr) * | 1991-12-20 | 1993-06-25 | Roussel Uclaf | Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments. |
-
1995
- 1995-03-16 DE DE19510862A patent/DE19510862A1/de not_active Withdrawn
-
1996
- 1996-03-15 DE DE59611391T patent/DE59611391D1/de not_active Expired - Fee Related
- 1996-03-15 CN CNB961926147A patent/CN1151792C/zh not_active Expired - Fee Related
- 1996-03-15 CZ CZ19972852A patent/CZ293771B6/cs not_active IP Right Cessation
- 1996-03-15 KR KR1019970706466A patent/KR19980703057A/ko not_active Ceased
- 1996-03-15 SK SK1238-97A patent/SK284442B6/sk unknown
- 1996-03-15 WO PCT/EP1996/001191 patent/WO1996028154A2/de not_active Ceased
- 1996-03-15 US US08/913,304 patent/US20010056086A1/en not_active Abandoned
- 1996-03-15 JP JP8527294A patent/JPH11501648A/ja not_active Withdrawn
- 1996-03-15 ES ES96906768T patent/ES2275273T3/es not_active Expired - Lifetime
- 1996-03-15 DK DK96906768T patent/DK0814803T3/da active
- 1996-03-15 CA CA002215373A patent/CA2215373A1/en not_active Abandoned
- 1996-03-15 EP EP96906768A patent/EP0814803B1/de not_active Expired - Lifetime
- 1996-03-15 HU HU9900313A patent/HUP9900313A3/hu unknown
- 1996-03-15 AT AT96906768T patent/ATE342055T1/de not_active IP Right Cessation
- 1996-03-15 PT PT96906768T patent/PT814803E/pt unknown
- 1996-03-17 IL IL11751596A patent/IL117515A/xx active IP Right Grant
- 1996-03-18 ZA ZA962176A patent/ZA962176B/xx unknown
- 1996-05-17 TW TW085105880A patent/TW503106B/zh not_active IP Right Cessation
-
1997
- 1997-09-15 NO NO974256A patent/NO974256L/no not_active Application Discontinuation
- 1997-09-16 PL PL96322253A patent/PL186085B1/pl not_active IP Right Cessation
- 1997-09-16 NZ NZ303672A patent/NZ303672A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT814803E (pt) | 2007-02-28 |
| AU713467B2 (en) | 1999-12-02 |
| ATE342055T1 (de) | 2006-11-15 |
| TW503106B (en) | 2002-09-21 |
| DE59611391D1 (de) | 2006-11-23 |
| ZA962176B (en) | 1996-07-29 |
| ES2275273T3 (es) | 2007-06-01 |
| CZ285297A3 (en) | 1997-12-17 |
| DE19510862A1 (de) | 1996-09-19 |
| WO1996028154A3 (de) | 1997-05-01 |
| CA2215373A1 (en) | 1996-09-19 |
| NO974256L (no) | 1997-11-14 |
| HUP9900313A3 (en) | 1999-11-29 |
| IL117515A (en) | 2003-07-31 |
| EP0814803A2 (de) | 1998-01-07 |
| MX9707008A (es) | 1997-11-29 |
| KR19980703057A (ko) | 1998-09-05 |
| PL322253A1 (en) | 1998-01-19 |
| HUP9900313A1 (hu) | 1999-06-28 |
| CN1151792C (zh) | 2004-06-02 |
| SK123897A3 (en) | 1998-02-04 |
| IL117515A0 (en) | 1996-07-23 |
| US20010056086A1 (en) | 2001-12-27 |
| CN1178463A (zh) | 1998-04-08 |
| NO974256D0 (no) | 1997-09-15 |
| PL186085B1 (pl) | 2003-10-31 |
| JPH11501648A (ja) | 1999-02-09 |
| WO1996028154A2 (de) | 1996-09-19 |
| CZ293771B6 (cs) | 2004-07-14 |
| EP0814803B1 (de) | 2006-10-11 |
| AU5004696A (en) | 1996-10-02 |
| NZ303672A (en) | 2000-07-28 |
| DK0814803T3 (da) | 2007-02-19 |
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