SK282091B6 - Spôsob imunomagnetického oddeľovania buniek - Google Patents
Spôsob imunomagnetického oddeľovania buniek Download PDFInfo
- Publication number
- SK282091B6 SK282091B6 SK1416-98A SK141698A SK282091B6 SK 282091 B6 SK282091 B6 SK 282091B6 SK 141698 A SK141698 A SK 141698A SK 282091 B6 SK282091 B6 SK 282091B6
- Authority
- SK
- Slovakia
- Prior art keywords
- cells
- tumor
- target cells
- genes
- expression
- Prior art date
Links
- 238000000926 separation method Methods 0.000 title claims description 5
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 49
- 238000000034 method Methods 0.000 claims abstract description 47
- 230000014509 gene expression Effects 0.000 claims abstract description 35
- 230000003211 malignant effect Effects 0.000 claims abstract description 23
- 238000009396 hybridization Methods 0.000 claims abstract description 4
- 210000004027 cell Anatomy 0.000 claims description 109
- 210000004881 tumor cell Anatomy 0.000 claims description 41
- 206010028980 Neoplasm Diseases 0.000 claims description 38
- 206010027476 Metastases Diseases 0.000 claims description 27
- 210000001519 tissue Anatomy 0.000 claims description 20
- 210000001185 bone marrow Anatomy 0.000 claims description 17
- 238000012215 gene cloning Methods 0.000 claims description 17
- 230000009401 metastasis Effects 0.000 claims description 15
- 241001465754 Metazoa Species 0.000 claims description 11
- 210000004369 blood Anatomy 0.000 claims description 11
- 239000008280 blood Substances 0.000 claims description 11
- 210000001165 lymph node Anatomy 0.000 claims description 9
- 238000000338 in vitro Methods 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 7
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims description 6
- 210000000988 bone and bone Anatomy 0.000 claims description 6
- 210000004185 liver Anatomy 0.000 claims description 6
- 108020004999 messenger RNA Proteins 0.000 claims description 6
- 210000000056 organ Anatomy 0.000 claims description 6
- 239000007787 solid Substances 0.000 claims description 5
- 108020004414 DNA Proteins 0.000 claims description 4
- 239000006285 cell suspension Substances 0.000 claims description 4
- 230000001413 cellular effect Effects 0.000 claims description 4
- 210000004072 lung Anatomy 0.000 claims description 4
- 210000003169 central nervous system Anatomy 0.000 claims description 3
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims description 3
- 230000002950 deficient Effects 0.000 claims description 3
- 210000005087 mononuclear cell Anatomy 0.000 claims description 3
- 210000002700 urine Anatomy 0.000 claims description 3
- 206010026673 Malignant Pleural Effusion Diseases 0.000 claims description 2
- 238000010370 cell cloning Methods 0.000 claims description 2
- 108020004707 nucleic acids Proteins 0.000 claims description 2
- 102000039446 nucleic acids Human genes 0.000 claims description 2
- 150000007523 nucleic acids Chemical class 0.000 claims description 2
- 230000008569 process Effects 0.000 claims description 2
- 108020004635 Complementary DNA Proteins 0.000 claims 1
- 206010025538 Malignant ascites Diseases 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 238000010367 cloning Methods 0.000 abstract description 11
- 206010061289 metastatic neoplasm Diseases 0.000 abstract description 9
- 230000001394 metastastic effect Effects 0.000 abstract description 8
- 206010006187 Breast cancer Diseases 0.000 description 11
- 208000026310 Breast neoplasm Diseases 0.000 description 11
- 239000012634 fragment Substances 0.000 description 8
- 201000011510 cancer Diseases 0.000 description 7
- 239000000047 product Substances 0.000 description 5
- 238000013459 approach Methods 0.000 description 4
- 238000003384 imaging method Methods 0.000 description 4
- 230000000306 recurrent effect Effects 0.000 description 4
- 206010009944 Colon cancer Diseases 0.000 description 3
- 206010061598 Immunodeficiency Diseases 0.000 description 3
- 239000002299 complementary DNA Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 210000005240 left ventricle Anatomy 0.000 description 3
- 238000003752 polymerase chain reaction Methods 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- 210000000278 spinal cord Anatomy 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 2
- 206010063045 Effusion Diseases 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 238000001574 biopsy Methods 0.000 description 2
- 210000005013 brain tissue Anatomy 0.000 description 2
- 238000004113 cell culture Methods 0.000 description 2
- 210000002808 connective tissue Anatomy 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 201000001441 melanoma Diseases 0.000 description 2
- 238000011206 morphological examination Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000011581 secondary neoplasm Diseases 0.000 description 2
- 238000010187 selection method Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 210000002536 stromal cell Anatomy 0.000 description 2
- 206010005949 Bone cancer Diseases 0.000 description 1
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102100031940 Epithelial cell adhesion molecule Human genes 0.000 description 1
- 101000920667 Homo sapiens Epithelial cell adhesion molecule Proteins 0.000 description 1
- 208000007433 Lymphatic Metastasis Diseases 0.000 description 1
- 206010027452 Metastases to bone Diseases 0.000 description 1
- 206010027468 Metastases to spine Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 238000002123 RNA extraction Methods 0.000 description 1
- 238000012300 Sequence Analysis Methods 0.000 description 1
- 108091023040 Transcription factor Proteins 0.000 description 1
- 102000040945 Transcription factor Human genes 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 210000004102 animal cell Anatomy 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000022131 cell cycle Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000012568 clinical material Substances 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 238000012606 in vitro cell culture Methods 0.000 description 1
- 230000000415 inactivating effect Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 210000005170 neoplastic cell Anatomy 0.000 description 1
- 235000003170 nutritional factors Nutrition 0.000 description 1
- 201000008968 osteosarcoma Diseases 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 210000003281 pleural cavity Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000037821 progressive disease Diseases 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
- YEENEYXBHNNNGV-XEHWZWQGSA-M sodium;3-acetamido-5-[acetyl(methyl)amino]-2,4,6-triiodobenzoate;(2r,3r,4s,5s,6r)-2-[(2r,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound [Na+].CC(=O)N(C)C1=C(I)C(NC(C)=O)=C(I)C(C([O-])=O)=C1I.O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 YEENEYXBHNNNGV-XEHWZWQGSA-M 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO961221A NO961221D0 (no) | 1996-03-26 | 1996-03-26 | Fremgangsmåte til å identifisere nye gener assosiert med setepreferert cancer mestastasedannelse |
| PCT/NO1997/000083 WO1997036004A1 (en) | 1996-03-26 | 1997-03-25 | Immuno-magnetic cell separation used in identification of genes associated with site-preferenced cancer methastasis formation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK141698A3 SK141698A3 (en) | 2000-01-18 |
| SK282091B6 true SK282091B6 (sk) | 2001-10-08 |
Family
ID=19899192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1416-98A SK282091B6 (sk) | 1996-03-26 | 1997-03-25 | Spôsob imunomagnetického oddeľovania buniek |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0894146B1 (no) |
| JP (1) | JP2000509250A (no) |
| KR (1) | KR19990087833A (no) |
| CN (1) | CN1214738A (no) |
| AT (1) | ATE251223T1 (no) |
| AU (1) | AU703262B2 (no) |
| BR (1) | BR9708256A (no) |
| CA (1) | CA2250202A1 (no) |
| CZ (1) | CZ286598A3 (no) |
| DE (1) | DE69725297T2 (no) |
| HU (1) | HUP9901786A3 (no) |
| IL (1) | IL126257A (no) |
| NO (1) | NO961221D0 (no) |
| NZ (1) | NZ331920A (no) |
| PL (1) | PL185182B1 (no) |
| RU (1) | RU2180963C2 (no) |
| SK (1) | SK282091B6 (no) |
| TR (1) | TR199801916T2 (no) |
| WO (1) | WO1997036004A1 (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
| US6682940B2 (en) | 1999-05-04 | 2004-01-27 | Dan A. Pankowsky | Products and methods for single parameter and multiparameter phenotyping of cells |
| US6828157B1 (en) | 1999-05-04 | 2004-12-07 | Dan A. Pankowsky | Products and methods for single parameter and multiparameter phenotyping of cells |
| FR2804126B1 (fr) * | 2000-01-21 | 2005-09-30 | Patrick Rambaud | Procede et systeme de gestion de lots de cellules immuno-competentes prelevees sur des sujets humains ou animaux en vue d'utilisations differees |
| WO2002036833A1 (en) * | 2000-11-06 | 2002-05-10 | Bio-Tech Imaging, Inc. | Method and kits for detecting hepatitis infected cells |
| FR2816322A1 (fr) * | 2000-11-06 | 2002-05-10 | Epigene | Methode de separation d'acide nucleique differemment exprime entre une cellule cible et une cellule de reference |
| CN115064209B (zh) * | 2022-08-17 | 2022-11-01 | 普瑞基准科技（北京）有限公司 | 一种恶性细胞鉴定方法及系统 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2593192A (en) * | 1992-09-14 | 1994-04-12 | Oystein Fodstad | Detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations |
| NO180658C (no) * | 1994-03-10 | 1997-05-21 | Oeystein Fodstad | Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner |
-
1996
- 1996-03-26 NO NO961221A patent/NO961221D0/no unknown
-
1997
- 1997-03-25 EP EP97915776A patent/EP0894146B1/en not_active Expired - Lifetime
- 1997-03-25 PL PL97329038A patent/PL185182B1/pl not_active IP Right Cessation
- 1997-03-25 SK SK1416-98A patent/SK282091B6/sk unknown
- 1997-03-25 JP JP9534283A patent/JP2000509250A/ja active Pending
- 1997-03-25 BR BR9708256A patent/BR9708256A/pt unknown
- 1997-03-25 CA CA002250202A patent/CA2250202A1/en not_active Abandoned
- 1997-03-25 IL IL12625797A patent/IL126257A/xx not_active IP Right Cessation
- 1997-03-25 HU HU9901786A patent/HUP9901786A3/hu unknown
- 1997-03-25 RU RU98119525/14A patent/RU2180963C2/ru not_active IP Right Cessation
- 1997-03-25 CN CN97193361A patent/CN1214738A/zh active Pending
- 1997-03-25 DE DE69725297T patent/DE69725297T2/de not_active Expired - Fee Related
- 1997-03-25 KR KR1019980707486A patent/KR19990087833A/ko not_active Application Discontinuation
- 1997-03-25 AU AU23116/97A patent/AU703262B2/en not_active Ceased
- 1997-03-25 TR TR1998/01916T patent/TR199801916T2/xx unknown
- 1997-03-25 CZ CZ982865A patent/CZ286598A3/cs unknown
- 1997-03-25 AT AT97915776T patent/ATE251223T1/de not_active IP Right Cessation
- 1997-03-25 NZ NZ331920A patent/NZ331920A/xx unknown
- 1997-03-25 WO PCT/NO1997/000083 patent/WO1997036004A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2311697A (en) | 1997-10-17 |
| EP0894146B1 (en) | 2003-10-01 |
| ATE251223T1 (de) | 2003-10-15 |
| NZ331920A (en) | 2000-01-28 |
| WO1997036004A1 (en) | 1997-10-02 |
| PL185182B1 (pl) | 2003-03-31 |
| HUP9901786A3 (en) | 2000-10-30 |
| RU2180963C2 (ru) | 2002-03-27 |
| SK141698A3 (en) | 2000-01-18 |
| CN1214738A (zh) | 1999-04-21 |
| DE69725297D1 (de) | 2003-11-06 |
| CZ286598A3 (cs) | 1999-02-17 |
| DE69725297T2 (de) | 2004-08-05 |
| IL126257A (en) | 2003-09-17 |
| EP0894146A1 (en) | 1999-02-03 |
| PL329038A1 (en) | 1999-03-01 |
| KR19990087833A (ko) | 1999-12-27 |
| CA2250202A1 (en) | 1997-10-02 |
| IL126257A0 (en) | 1999-05-09 |
| TR199801916T2 (xx) | 1998-12-21 |
| BR9708256A (pt) | 1999-08-03 |
| AU703262B2 (en) | 1999-03-25 |
| JP2000509250A (ja) | 2000-07-25 |
| NO961221D0 (no) | 1996-03-26 |
| HUP9901786A2 (hu) | 1999-09-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2527777B2 (ja) | 細胞の由来組識および／または細胞の異常度を特徴付ける方法 | |
| JP2002536635A (ja) | 体液から腫瘍細胞を濃縮するか又は除去する方法及びかかる目的に適したキット | |
| JP2003515317A (ja) | 病的事象の検出のための組成物及び方法 | |
| CN110004147B (zh) | 一种在人血浆中筛选的上皮细胞粘附分子EpCAM的核酸适体及其制备方法和应用 | |
| CN109097477A (zh) | 一种用于乳腺癌诊断的circRNA标志物及其应用 | |
| CN109112216A (zh) | 三重qPCR检测DNA甲基化的试剂盒和方法 | |
| US20210318310A1 (en) | Methods for monitoring polymorphonuclear myeloid derived suppressor cells | |
| SK282091B6 (sk) | Spôsob imunomagnetického oddeľovania buniek | |
| CA2518933C (en) | Method of detecting colon cancer marker | |
| CN105483246B (zh) | 基因的差异表达在口腔癌诊断中的应用 | |
| KR101704828B1 (ko) | 체액 내 세포밖 소포체의 단백질 또는 유전자 분석을 통한 염증성 질환 진단 방법 | |
| Sato et al. | Applicability of Nanotrap Sg as a semen detection kit before male-specific DNA profiling in sexual assaults | |
| AU2003260389B2 (en) | Method for the immunocytological or molecular detection of disseminated tumor cells in a body fluid and kit that is suitable therefor | |
| CN114085911B (zh) | 一种检测肿瘤细胞或肿瘤细胞碎片的方法 | |
| JP2800850B2 (ja) | 新生物形成の検出方法 | |
| JP2020512813A (ja) | がんのスクリーニング、診断、治療、及び再発における巨細胞の核酸の特徴付けの使用方法 | |
| RU2707083C1 (ru) | Способ обнаружения или выделения/получения циркулирующей опухолевой клетки, использующий метод пролиферации клеток | |
| CN112143783B (zh) | 一种可识别混合物对复杂生物体系的鉴别方法 | |
| CN114134116A (zh) | 预测结直肠癌患者化疗药物疗效的试剂盒及其应用 | |
| RU2665965C1 (ru) | Способ скрининга злокачественных новообразований у человека | |
| Oyama et al. | Establishment of a novel patient-derived Ewing’s sarcoma cell line, NCC-ES1-C1 | |
| RU2801094C1 (ru) | Способ определения группы риска для пациентов с множественной миеломой, осложненной плазмоцитомой | |
| MXPA98007590A (en) | Immunomagnetic separation of cells, used in the identification of genes associated with formation of cancer metastases with preference for a yes | |
| US20240085306A1 (en) | Method for enriching cells or cell nuclei | |
| Zhou et al. | Protocol to dissociate and isolate wide-diversity single cells by density gradient centrifugation from human hepatoblastoma tissue |