SK281919B6 - Derivát alkenylbenzoylguanidínu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje - Google Patents
Derivát alkenylbenzoylguanidínu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje Download PDFInfo
- Publication number
- SK281919B6 SK281919B6 SK1081-96A SK108196A SK281919B6 SK 281919 B6 SK281919 B6 SK 281919B6 SK 108196 A SK108196 A SK 108196A SK 281919 B6 SK281919 B6 SK 281919B6
- Authority
- SK
- Slovakia
- Prior art keywords
- methyl
- diaminomethylene
- formula
- methylsulfonylbenzamide
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19531138A DE19531138A1 (de) | 1995-08-24 | 1995-08-24 | Alkenyl-benzoylguanidin-Derivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK108196A3 SK108196A3 (en) | 1997-06-04 |
| SK281919B6 true SK281919B6 (sk) | 2001-09-11 |
Family
ID=7770272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1081-96A SK281919B6 (sk) | 1995-08-24 | 1996-08-21 | Derivát alkenylbenzoylguanidínu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5731351A (xx) |
| EP (1) | EP0760365B1 (xx) |
| JP (1) | JPH09124583A (xx) |
| KR (1) | KR970010739A (xx) |
| CN (1) | CN1063438C (xx) |
| AR (1) | AR004680A1 (xx) |
| AT (1) | ATE198470T1 (xx) |
| AU (1) | AU718430B2 (xx) |
| BR (1) | BR9603508A (xx) |
| CA (1) | CA2183937A1 (xx) |
| CZ (1) | CZ288609B6 (xx) |
| DE (2) | DE19531138A1 (xx) |
| DK (1) | DK0760365T3 (xx) |
| ES (1) | ES2154370T3 (xx) |
| GR (1) | GR3035481T3 (xx) |
| HU (1) | HUP9602331A3 (xx) |
| MX (1) | MX9603568A (xx) |
| NO (1) | NO306991B1 (xx) |
| PL (1) | PL315800A1 (xx) |
| PT (1) | PT760365E (xx) |
| SI (1) | SI0760365T1 (xx) |
| SK (1) | SK281919B6 (xx) |
| TW (1) | TW401390B (xx) |
| UA (1) | UA41393C2 (xx) |
| ZA (1) | ZA967204B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4328352A1 (de) * | 1993-08-24 | 1995-03-02 | Hoechst Ag | Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19608161A1 (de) * | 1996-03-04 | 1997-09-11 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| IL126276A0 (en) * | 1997-09-24 | 1999-05-09 | Hoechst Marion Roussel De Gmbh | The use of an inhibitor of the na+/H+ exchanger for the production of a medicament for the treatment or prophylaxis of disorders of the central nervous system |
| WO2000030624A2 (en) * | 1998-11-26 | 2000-06-02 | Merck Patent Gmbh | Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus |
| DE19929857A1 (de) * | 1999-06-29 | 2001-01-04 | Merck Patent Gmbh | Verfahren zur Herstellung eines 4-(Pyrrol-1-yl)-benzoylguanidinderivates |
| BR112013011135A2 (pt) | 2010-11-05 | 2016-08-02 | Zhejiang Hisun Pharm Co Ltd | ''composto,método para a preparação do composto,composição farmacêutica e uso do composto'' |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| ATE144248T1 (de) * | 1992-07-01 | 1996-11-15 | Hoechst Ag | 3,4,5-substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament |
| DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4417004A1 (de) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| IL114670A0 (en) * | 1994-08-05 | 1995-11-27 | Fujisawa Pharmaceutical Co | Guanidine derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE4430916A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Alkyl-benzoylguanidin-Derivate |
-
1995
- 1995-08-24 DE DE19531138A patent/DE19531138A1/de not_active Withdrawn
-
1996
- 1996-07-24 TW TW085109043A patent/TW401390B/zh not_active IP Right Cessation
- 1996-08-16 CZ CZ19962436A patent/CZ288609B6/cs not_active IP Right Cessation
- 1996-08-16 SI SI9630293T patent/SI0760365T1/xx unknown
- 1996-08-16 DE DE59606269T patent/DE59606269D1/de not_active Expired - Fee Related
- 1996-08-16 EP EP96113175A patent/EP0760365B1/de not_active Expired - Lifetime
- 1996-08-16 ES ES96113175T patent/ES2154370T3/es not_active Expired - Lifetime
- 1996-08-16 PT PT96113175T patent/PT760365E/pt unknown
- 1996-08-16 AT AT96113175T patent/ATE198470T1/de not_active IP Right Cessation
- 1996-08-16 DK DK96113175T patent/DK0760365T3/da active
- 1996-08-19 AU AU62148/96A patent/AU718430B2/en not_active Ceased
- 1996-08-21 SK SK1081-96A patent/SK281919B6/sk unknown
- 1996-08-21 UA UA96083321A patent/UA41393C2/uk unknown
- 1996-08-22 BR BR9603508A patent/BR9603508A/pt active Search and Examination
- 1996-08-22 MX MX9603568A patent/MX9603568A/es not_active IP Right Cessation
- 1996-08-22 CA CA002183937A patent/CA2183937A1/en not_active Abandoned
- 1996-08-22 CN CN96111527A patent/CN1063438C/zh not_active Expired - Fee Related
- 1996-08-23 HU HU9602331A patent/HUP9602331A3/hu unknown
- 1996-08-23 NO NO963525A patent/NO306991B1/no not_active IP Right Cessation
- 1996-08-23 US US08/701,993 patent/US5731351A/en not_active Expired - Fee Related
- 1996-08-23 KR KR1019960035109A patent/KR970010739A/ko not_active Application Discontinuation
- 1996-08-23 ZA ZA967204A patent/ZA967204B/xx unknown
- 1996-08-23 PL PL96315800A patent/PL315800A1/xx unknown
- 1996-08-23 JP JP8239937A patent/JPH09124583A/ja active Pending
- 1996-08-23 AR ARP960104089A patent/AR004680A1/es not_active Application Discontinuation
-
2001
- 2001-02-28 GR GR20010400323T patent/GR3035481T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9603508A (pt) | 1998-05-12 |
| EP0760365A3 (de) | 1998-07-08 |
| AR004680A1 (es) | 1999-03-10 |
| HUP9602331A2 (en) | 1997-05-28 |
| PL315800A1 (en) | 1997-03-03 |
| KR970010739A (ko) | 1997-03-27 |
| DE59606269D1 (de) | 2001-02-08 |
| CN1150947A (zh) | 1997-06-04 |
| AU6214896A (en) | 1997-02-27 |
| ES2154370T3 (es) | 2001-04-01 |
| SK108196A3 (en) | 1997-06-04 |
| HU9602331D0 (en) | 1996-10-28 |
| AU718430B2 (en) | 2000-04-13 |
| DE19531138A1 (de) | 1997-02-27 |
| GR3035481T3 (en) | 2001-05-31 |
| ZA967204B (en) | 1997-03-03 |
| DK0760365T3 (da) | 2001-05-14 |
| EP0760365B1 (de) | 2001-01-03 |
| JPH09124583A (ja) | 1997-05-13 |
| UA41393C2 (uk) | 2001-09-17 |
| HUP9602331A3 (en) | 1999-12-28 |
| US5731351A (en) | 1998-03-24 |
| EP0760365A2 (de) | 1997-03-05 |
| NO963525D0 (no) | 1996-08-23 |
| NO963525L (no) | 1997-02-25 |
| CA2183937A1 (en) | 1997-02-25 |
| CZ243696A3 (en) | 1997-03-12 |
| CN1063438C (zh) | 2001-03-21 |
| ATE198470T1 (de) | 2001-01-15 |
| MX9603568A (es) | 1997-06-28 |
| PT760365E (pt) | 2001-05-31 |
| TW401390B (en) | 2000-08-11 |
| SI0760365T1 (en) | 2001-08-31 |
| NO306991B1 (no) | 2000-01-24 |
| CZ288609B6 (cs) | 2001-07-11 |
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