SK281442B6 - Bicyklické amidínové deriváty, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie - Google Patents

Bicyklické amidínové deriváty, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie Download PDF

Info

Publication number
SK281442B6
SK281442B6 SK390-97A SK39097A SK281442B6 SK 281442 B6 SK281442 B6 SK 281442B6 SK 39097 A SK39097 A SK 39097A SK 281442 B6 SK281442 B6 SK 281442B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
amino
methyl
nxy
Prior art date
Application number
SK390-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK39097A3 (en
Inventor
James Edwin Macdonald
William Calvin Shakespeare
Robert John Murray
James Russell Matz
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of SK39097A3 publication Critical patent/SK39097A3/sk
Publication of SK281442B6 publication Critical patent/SK281442B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
SK390-97A 1995-08-10 1995-08-10 Bicyklické amidínové deriváty, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie SK281442B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1995/001896 WO1997006158A1 (en) 1995-08-10 1995-08-10 Bicyclic amidine derivatives useful in therapy

Publications (2)

Publication Number Publication Date
SK39097A3 SK39097A3 (en) 1998-08-05
SK281442B6 true SK281442B6 (sk) 2001-03-12

Family

ID=10768883

Family Applications (1)

Application Number Title Priority Date Filing Date
SK390-97A SK281442B6 (sk) 1995-08-10 1995-08-10 Bicyklické amidínové deriváty, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie

Country Status (7)

Country Link
KR (1) KR970706272A (ko)
BR (1) BR9509297A (ko)
CZ (1) CZ287969B6 (ko)
EE (1) EE9700207A (ko)
IS (1) IS4452A (ko)
SK (1) SK281442B6 (ko)
WO (1) WO1997006158A1 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9701681D0 (sv) 1997-05-05 1997-05-05 Astra Ab New compounds
US6166030A (en) * 1997-05-05 2000-12-26 Astra Aktiebolag Compounds
DE19844291A1 (de) * 1998-09-18 2000-03-23 Schering Ag Benzoxazin- und Benzothiazin-Derivate und deren Verwendung in Arzneimitteln
SE9803710L (sv) 1998-09-25 2000-03-26 A & Science Invest Ab Användning av vissa substanser för behandling av nervrotsskador
US7115557B2 (en) 1998-09-25 2006-10-03 Sciaticon Ab Use of certain drugs for treating nerve root injury
US7229986B2 (en) * 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
PE20020870A1 (es) 2001-02-13 2002-11-18 Aventis Pharma Gmbh 6,7,8,9-tetrahidro-5h-benzocicloheptenil aminas aciladas
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
AR038420A1 (es) 2002-02-15 2005-01-12 Glaxo Group Ltd Compuesto de amida, procedimiento para la preparacion del mismo, su uso para la fabricacion de un medicamento y composicion farmaceutica que lo comprende
EP1388535A1 (en) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylated arylcycloalkylamines and their use as pharmaceuticals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6286294A (en) * 1993-03-23 1994-10-11 Astra Aktiebolag Guanidine derivatives useful in therapy
EP0713483B1 (en) * 1993-08-12 2003-01-15 AstraZeneca AB Amidine derivatives with nitric oxide synthetase activities
DE69511260T2 (de) * 1994-05-07 2000-03-16 Astra Ab Bicyclische amidinderivate als no-synthetase inhibitoren

Also Published As

Publication number Publication date
SK39097A3 (en) 1998-08-05
BR9509297A (pt) 1998-07-07
CZ108697A3 (cs) 1998-04-15
WO1997006158A1 (en) 1997-02-20
EE9700207A (et) 1998-02-16
IS4452A (is) 1997-03-25
KR970706272A (ko) 1997-11-03
CZ287969B6 (cs) 2001-03-14

Similar Documents

Publication Publication Date Title
US5807885A (en) Amidine derivatives with nitric oxide synthetase activities
EP0690851B1 (en) Guanidine derivatives useful in therapy
EP0759027B1 (en) Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
US5721247A (en) Isothiourea derivatives useful in therapy
SK281442B6 (sk) Bicyklické amidínové deriváty, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie
RU2157802C2 (ru) Бициклические производные изотиомочевины, способ их получения и фармацевтическая композиция на их основе
AU734394B2 (en) Compounds
SK140599A3 (en) Amidine derivatives as inhibitors of nitric oxide synthase
RU2155761C2 (ru) Бициклические производные амидина, способ их получения, фармацевтическая композиция и способ ингибирования синтетазы окиси азота
HUT77376A (hu) Biciklusos amidinszármazékok, eljárás előállításukra, a vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk
IL115482A (en) Bicyclic amidine derivatives, their preparation and pharmaceutical compositions containing them
NZ290918A (en) Bicyclic amidines
TW317565B (ko)
CZ388999A3 (cs) Sloučeniny
MXPA00001586A (es) Proceso para la creacion de un plano optico que genera una vision en tercera dimension.
MXPA97005965A (en) Derivatives of istitiourea biciclicos, useful in tera